• Title/Summary/Keyword: 중추원

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Clinical Manifestation of Children with Failure to Thrive (Failure to Thrive를 주소로 내원한 환아들의 임상상)

  • Moon, Jeong-Hee;Kim, Ji-Young;Beck, Nam-Sun
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.3 no.1
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    • pp.68-74
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    • 2000
  • Purpose: This study was to investigate the clinical manifestations of FTT in children. Methods: From March 1997 to July 1999, clinical observations were made on patients with FTT who had visited to Samsung Medical Center. Detailed histories and through physical examinations were taken, and when suspected organic FTT, basic laboratory studies were done. Results: Upon the review of medical records, we investigated the clinical manifestations of 74 children, aged 1 month and 13 year 1 month. The causes of FTT were composed of either physiologic (47.8%) or pathologic (52.2%) ones. Among the physiologic FTT, were there familial short stature (FSS, 14.5%), intrauterine growth retardation (IUGR, 14.5%), constitutional growth delay (CGD, 11.6%), idiosyncrasy and prematurity. Among pathologic causes, neurologic disorders (20%) are the most common causes of FTT, and then follow by GI (13.4%), allergic and infectious disorders in decreasing order. The data showed that average caloric intake in patients with FTT was 76,2% of recommended amount. FTT patients with CGD, IUGR, and idiosyncrasy had tendency to take small foods. The FTT children with prematurity, IUGR and pathologic FTT, were short and thin for their ages. However FTT children with CGD and FSS had tendency to be thin with relatively normal heights for their ages, in comparison with those of the children with prematurity, IUGR and pathologic FTT. Conclusion: The diagnosis of FTT was easily obtained with simple and through medical history, physical examination, and minimal laboratory tests. In this study, organic FTT was more prevalent than physiologic one. This results indicate that early intervention is mandatory, because children may develop significant long-term sequelae from nutritional deficiency.

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원전 제어실의 인간공학 실험평가연구현황

  • 이현철;오인석;차경호;심봉식
    • Proceedings of the ESK Conference
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    • 1994.04a
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    • pp.157-157
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    • 1994
  • 원자력발전소 운영의 중추적 역할을 담당하고 있는 운전원과 발전소시스템 사이에서 발생하는 인간공학적 요인(인적요인)은 다중방호벽의 존재와 자동화 기술의 확대에도 불구하고 원전의 가동 성 및 안전성을 위협하는 최대의 요인이다. 최근 원자력발전소 시스템에 고도화된 전자공학 및 인공 지능기술 등이 반영되고 있는 추세이나 이러한 기술의 도입이 운전원과의 복합적 상호작용관점에서 원전의 안전성과 효율성에 적합한가를 실험적으로 평가할 수 있는 실험평가기술의 확보가 필요한 실정이다. 한국원자력연구소에서는 차세대 주제어실의 설계 및 평가를 위한 실험적 자료의 생성 및 설계 대안의 평가를 위한 기술확보라는 목적을 가지고 1992년도부터 수행하고 있다. 1992년도(1차년 도)에는 새로운 주제어실에서 실험적으로 평가해야 할 평가항목을 구체화하였고, 4년간의 연구추진 내용을 설정하였다. 기존의 원자력산업계에서 요구하고 있는 인가/허가 요건, 사업자요건서, 인간 공학분야에서 제기하고 있는 문제점 등을 분석하여 10개의 실험평가항목을 도출하였으며, 실험평가 항목을 실제로 실험을 통하여 연구하기 위한 장비 및 설비 그리고 소요기술 등을 고려하여 연구방향을 설정하였다. 1993년도(2차년도)에는 차세대 주제어실의 특징을 규명하고 실험연구의 대상시스템을 설정하였다. 설정된 대상시스템을 기능별로 분석하여 설계변수를 도출하였으며, 인간공학 실험실의 구축에 필수적인 원자력발전소 시뮬레이터의 기능요건 및 실험실의 구성요건 등을 개발하고 있다. 3차년도부터는 인간공학실험을 수행하면서 자료분석체계의 개발, 원전직무 시나리오의 개발, 측정방법의 개발, 인간공학 실험실의 설계, 구축 및 검증, 평가기법 연구, 실시간 자료수집체계의 개발 등을 수행할 예정이며, 연구종료시점인 1996년도(5차년도)에는 원자력발전소 주제어실의 인간공학적 평가를 위한 실험 환경의 구축 및 실험평가기술의 확립이라는 목표가 달성된다.하는 것으로 간주된다. 2. KR 53234 10mg/kg 정맥투여후의 최고혈중농도는 1.14ug/ml, 반감기는 0.50hr, 분포용적은 2.2L이었다. 20mg/kg 경구 투여시의 최소 혈중 농도는 0.33 ug/ml, 소실반감기는 1.5시간, AUC는 0.942ug.hr/ml, 분포용적 11L, Ka는 3.05 $hr^{-1}$ 그리고 Cl는 5.3L/hr/kg이었다. 이는 KR 53170에서와 같이 매우 적은량이 흡수되고 배설되었다. 3. KR 53170의 혈청단백 결합율은 5-500 ug/ml 범위에서 78.7-86.2%이었고 KR 53234의 혈청단백결합율은 5-100 ug/ml 범위에서 79.6-71.2%이었다.이었다.tic techniques, and we have recently cloned two of the major subunits; some of the data will be presented.LIFO, 우선 순위 방식등을 선택할 수 있도록 확장하였다. SIMPLE는 자료구조 및 프로그램이 공개되어 있으므로 프로그래머가 원하는 기능을 쉽게 추가할 수 있는 장점도 있다. 아울러 SMPLE에서 새로이 추가된 자료구조와 함수 및 설비제어 방식등을 활용하여 실제 중형급 시스템에 대한 시뮬레이션 구현과 시스템 분석의 예를 보인다._3$", chain segment, with the activation energy of carriers from the shallow trap with 0.4[eV], in he amorphous regions.의 증발산율은 우기의 기상자료를 이용하여 구한 결과 0.05 - 0.10 mm/hr 의 범위로서 이로 인한 강우손실량은 큰 의미가 없음을 알았다.재발이 나타난 3례의 환자를 제외한 9례 (75%)에서는 현재까지 재발소견을 보이지 않고 있다. 이러한 결과는 다른 보고자들과 유사한 결과를 보이고 있

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MR Imaging Characteristics of Primary T-Cell Lymphoma of the Cauda Equina: A Case Report and Literature Review (말총의 원발성 T세포 림프종에서 MR 영상 소견: 증례 보고와 문헌 고찰)

  • Younguk Kim;Guen Young Lee;Sujin Kim;Kwang-sup Song;Hee Sung Kim
    • Journal of the Korean Society of Radiology
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    • v.82 no.6
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    • pp.1613-1618
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    • 2021
  • Primary central nervous system lymphoma is a rare form of extranodal non-Hodgkin lymphoma, and primary T-cell lymphoma of the cauda equina is extremely rare. We describe a case involving a 56-year-old female who presented with low back pain and radiating leg pain for 4 months. MRI of the lumbar spine revealed an elongated, multinodular intradural lesion of approximately 10 cm from the L4 body to the S2 body level with iso-signal intensity on T1-weighted imaging, heterogeneous iso- and high-signal intensity on T2-weighted imaging, and a heterogeneous intense enhancement on gadolinium contrast-enhanced T1-weighted imaging. A peripheral T-cell lymphoma of the cauda equina was diagnosed on the basis of immunohistochemical and T-cell receptor gamma gene rearrangement analysis after intradural biopsy of the mass.

Effect of the Water Extract of Persicae Semen on Promotion of Axon Regeneration (도인(桃仁)이 중추신경 재생 촉진에 미치는 영향)

  • Shin, Jin-Bong;Moon, Goo;Lee, Jong-Deuk;Won, Jin-Hee;Lee, Jae-Won
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.21 no.1
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    • pp.145-152
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    • 2007
  • Following CNS injury, inhibitory influences at the site of axonal damage occur. Glial cells become reactive and form a glial scar, gliosis. Astrocyte-rich gliosis relates with up-regulation of GFAP and CD81, and eventually becomes physical and mechanical barrier to axonal regeneration. It is postulated that the astrocytic reaction is absent, regeneration of axons can occur. And it was reported that treatment with anti CD81 antibodies enhanced functional recovery in the rat with spinal cord injury. So in this current study, the author investigated the effect of the water extract of Persicae Semen on the regulation of GFAP and CD81 that increase when gliosis occurs. Persicae Semen decreased the expression of GFAP and CD81 in astrocyte cell by ELISA method. Persicae Semen decreased the RNA expression of CD81 and GFAP. The proteins that separate in whole cell were analaysed by western blot, and the expression of GFAP and CD81 was decreased. In vivo, rats brains were peformed cortical stab wound, the water extracts of Persicae Semen were injected for 7 days, 30 days. As a result, GFAP and CD81 expression were decreased in immunohistochemistry. These findings demonstrate that Persicae Semen decreases GFAP and CD81 expression. Accordingly, Persicae Semen could be a candidate for promotion of axon regeneration after CNS injury.

A Study on the Diffusion of NCS-based Curriculum in Junior Colleges based on the Analysis of Research Trends (NCS기반교육 연구동향 분석을 통한 전문대학의 NCS확산연구)

  • Choi, Yeon-Sook
    • Journal of the Korea Convergence Society
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    • v.11 no.4
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    • pp.221-231
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    • 2020
  • In Korea's national competency standards, competency is defined as a concept that includes the common skills required to be a member of an organization, the knowledge, skills, attitudes, and values necessary to perform the task, in addition to the skills necessary to perform the task in the field. This study examines the recently published NCS-related paper, and summarizes the key findings in the areas of the design and operation of NCS-based curriculum, key factors that should be included in the design of each individual NCS-based curriculum, positive effects and negative effects of NCS-based education and training processes. Based on these findings and educational implications, the feasibility of expanding the NCS-based curriculum in junior colleges is discussed. In addition, the roles of Human Resources Development Service of Korea and NCS web site are discussed and some suggestions concerning their roles are provided.

Design and manufacture of supersonic waves system that there is no invasion that there is no stimulation of embedded base for crush bone fracture patient's treatment (II) (파쇄 골절환자의 치료를 위한 임베디드 기반의 무자극, 무침습 초음파 시스템의 설계 및 제작(II))

  • Kim, Whi-Young
    • Journal of the Korea Computer Industry Society
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    • v.7 no.5
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    • pp.583-590
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    • 2006
  • BT technology, medical treatment engineering technology is offering important role and grow by creative technology. Specially, bone fracture treatment can achieve very important role in research of bone, physiology and dynamics of bone is very useful patient's diagnostic and treatment in presence at a sickbed. <중략>Furthermore embedded base of in administration aspect as well as if supersonic waves curer is treatment innocuously and without invasion very efficient tell. If apply supersonic waves in bone fracture treatment, can reduce curer about 40%. Operation frequency through bone fracture treatment supersonic waves curer of embedded base designs and manufactured 1m Hz, 1.2mHz, 1.3mHz, 1.4mHz, supersonic waves origination that have 1.5mHz's tranducer, and embodied protocol in PDA base in this research, and did so that is interfaced to general PC. If is using but supplement research water that see clinically by diagnosis in city, is seen to become convenient medical treatment assistance mounting to bone fracture patient's treatment and courtesy call. Specially, tried to approach basic form after modeling processing if may be applied variously to physiotherapy, orthopaedics patient who gouge late, and study standardization special quality little more.

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Consideration for Application of Wind Environment Assement on Ecological Parks in Cities (도시 생태공원의 풍환경 평가 적용에 관한 고찰)

  • Kim, Wonsul;Jung, Il Won;Kwon, Ji-Hye
    • Journal of Wetlands Research
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    • v.21 no.spc
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    • pp.117-122
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    • 2019
  • City parks play an important role in reducing the air pollution and mitigating the city heat island effect caused by global warming. However, from July 2020, restricted parks over 20-year will be partially lifted due to sunset regulation on parks. As a result, the government and local governments have been making efforts to revitalize parks, such as creating ecological parks and securing park sites. However, building winds generated by high-rise buildings constructed around ecological parks in the city may cause discomfort to pedestrians and threaten the ecosystems of plants and animal that live in ecological parks. There are no clearly proposed as standards for wind environment assessment in Korea, but also it has been rarely studied on pedestrian wind environment. In this study, wind environment studies have been reviewed to find the important parameters related to wind environment assessment. Further, wind climate analysis using wind data obtained by Seoul meterological station was performed to examine the possibility of applicability of the wind environment assessment on the city ecological parks.

Acute cerebral infarction associated with thrombocytopenia in primary Sjogren's syndrome : A Case Report (저혈소판증을 동반한 급성 대뇌경색을 보인 원발성 쇼그렌 증후군 1례)

  • Choi, Pahn Kyu;Kang, Hyun Goo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.7
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    • pp.565-568
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    • 2017
  • Sjogren's syndrome is an autoimmune disease characterized by dry mouth and neutropenia. Although it does not commonly involve the central nervous system, Sjogren's syndrome sometimes affects small vessels through microangiopathic alterations. A 34-year-old woman was hospitalized for left upper quadrantanopia and a tingling sensation in the left hemibody. Brain magnetic resonance imaging revealed acute infarction in the right posterior cerebral artery territory. In laboratory tests, antinuclear (FANA2+) and anti-DNA antibodies (anti-SS-A (Ro)) were detected. Salivary gland scintigraphy revealed moderately decreasedexcretion of saliva. Based on these findings, we concluded she had Sjogren's syndrome. As in this patient, large vessel involvement in Sjogren's syndrome is far less common. Furthermore, it is difficult to administer antiplatelet drugsto patients with thrombocytopenia in Sjogren's syndrome. This is a case of the patient with Sjogren's syndrome that involved thrombocytopenia and large vessel invasion who was treated with antiplatelet drugs and hydroxychloroquine.

The Study on the Connection of SWMM and HEC-RAS for Urban Flood Forecasting (도시홍수예보를 위한 과 의 SWMM과 HEC-RAS의 연계 검토)

  • Yoon, Seong-Sim;Bae, Deg-Hyo
    • Proceedings of the Korea Water Resources Association Conference
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    • 2008.05a
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    • pp.340-344
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    • 2008
  • 최근의 급속한 도시화로 인한 불투수면적의 증가는 첨두유량의 증가, 홍수도달시간의 단축을 야기해 도시유역의 홍수 피해를 증가시키고 있다. 특히 하천 홍수위 상승에 의한 외수피해와 순간적인 집중호우에 의해 도로 노면수의 배수불량에서 기인하는 내수피해가 겹치는 경우 도시유역의 홍수피해는 더욱 가중된다. 이러한 도시홍수의 피해를 방지하기 위해서는 구조적 또는 비구조적인 대책수립이 필요하다. 구조적 대책의 경우 효과적이나 예산과 공기 등의 문제가 있으며, 중추적인 해결책이 되지 않으므로 도시홍수예보 시스템의 개발이 필요하다. 일반적으로 홍수예보에는 유출해석모형이 활용되고 있다. 유출해석모형 중 SWMM 모형은 맨홀 및 우수관망의 고려가 가능하여 하천과 우수관로가 연계된 도시 유출특성의 모의가 가능하여 도시홍수예보에 적합한 모형이다. 그러나 SWMM은 소배수유역의 분할 및 계산시간의 제약으로 대체적으로 유역면적이 $100km^2$ 내에 적용되는 한계를 가지고 있다. 따라서 본류 및 지류하천과 우수관로가 연계되는 $100km^2$ 이상인 도시유역의 홍수예보를 위해서는 우수관망 해석 및 하천흐름해석의 연계가 필요하다. 본 연구에서는 중규모 유역의 도시홍수예보를 위해 SWMM과 HEC-RAS 모형을 연계하는 방안을 제시하였다. 중랑천 유역을 대상으로 SWMM 모형을 이용하여 소유역의 지표 및 관망유출과 지류하천의 유출 분석을 수행하였고, 중랑천 본 류구간에 대해서는 HEC-RAS 모형을 구축하여 하천의 부정류 해석을 수행하였다. 또한, SWMM으로 계산된 배수구역별 유출해석 결과를 HEC-RAS의 지류유입량으로 활용하여 본류의 지류유입 영향을 고려하도록 하였으며, 원할한 연계를 위해 SWMM과 HEC-RAS를 연계한 시스템을 구축하였다. 결과적으로 SWMM과 HEC-RAS를 연계시스템 통한 모의유량이 관측유량과 유사한 결과를 보였으며, 도시홍수예보를 위한 SWMM과 HEC-RAS의 연계는 복잡한 도시유역의 홍수관리에 활용성이 클 것으로 판단된다.

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Separation and Recovery of F-gases (불화 온실 가스 저감 및 분리회수 기술의 연구개발 동향)

  • Nam, Seung-Eun;Park, Ahrumi;Park, You-In
    • Membrane Journal
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    • v.23 no.3
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    • pp.189-203
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    • 2013
  • F-gases, gases containing fluorine such as perfluorocarbons (PFCs), sulfurhexafluoride ($SF_6$), nitrogen trifluoride ($NF_3$) are known to have green house effects. Although the net emission rates of gases containing fluorine are much lower than those of $CO_2$, their contribution to global warming cannot be ignored because of their extremely high global warming potential (GWP). F-gases mainly have been used for a variaty of applications in the semiconductor/LCD processes and in the electric power distribution industry of the national key industry. One of practical solutions of controlling the emission rates of F-gases is to reuse by separation and recovery of F-gases of low concentration from the gases mixtures with nitrogen or air. This work investigates some methods for F-gases recovery and separation around the membrane-based process.