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http://dx.doi.org/10.5762/KAIS.2017.18.7.565

Acute cerebral infarction associated with thrombocytopenia in primary Sjogren's syndrome : A Case Report  

Choi, Pahn Kyu (Department of Neurology, Chosun University School of Medicine)
Kang, Hyun Goo (Department of Neurology, Chosun University School of Medicine)
Publication Information
Journal of the Korea Academia-Industrial cooperation Society / v.18, no.7, 2017 , pp. 565-568 More about this Journal
Abstract
Sjogren's syndrome is an autoimmune disease characterized by dry mouth and neutropenia. Although it does not commonly involve the central nervous system, Sjogren's syndrome sometimes affects small vessels through microangiopathic alterations. A 34-year-old woman was hospitalized for left upper quadrantanopia and a tingling sensation in the left hemibody. Brain magnetic resonance imaging revealed acute infarction in the right posterior cerebral artery territory. In laboratory tests, antinuclear (FANA2+) and anti-DNA antibodies (anti-SS-A (Ro)) were detected. Salivary gland scintigraphy revealed moderately decreasedexcretion of saliva. Based on these findings, we concluded she had Sjogren's syndrome. As in this patient, large vessel involvement in Sjogren's syndrome is far less common. Furthermore, it is difficult to administer antiplatelet drugsto patients with thrombocytopenia in Sjogren's syndrome. This is a case of the patient with Sjogren's syndrome that involved thrombocytopenia and large vessel invasion who was treated with antiplatelet drugs and hydroxychloroquine.
Keywords
Autoimmune disease; Neutropenia; Sjogren's syndrome; Stroke; Thrombocytopenia;
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