• The Journal of the Korea Contents Association
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• v.18 no.2
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• pp.248-261
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• 2018

This study, the Fear of Missing Out Scale (FoMO Scale) developed by Przybylski et al. (2013) was adapted and validated to the Korean culture. 3-factors were constructed through EFA and item content analysis. In the CFA, 3 models were constructed to verify the fit of the model. Compared the goodness of fit, 3-factors model with 8 items proved to be the most appropriate. Sub-factors extracted through the characteristic context and rationale of Korean culture are 'belonging needs', 'extrinsic motivation', and 'relative deprivation'. K-FoMO scale and the reliability level of each sub-factor were good. Convergent validity was assessed by significant correlation the K-FoMO scores with life satisfaction, positive emotions, negative emotions, and SNS addiction proneness. Discriminant validity was assessed by low correlation with gratitude. At the end, limitation and suggestions for the future research were discussed.

• Journal of Trauma and Injury
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• v.26 no.1
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• pp.6-13
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• 2013

Purpose: Sulforaphane is a naturally-occurring isothiocyanate abundant in broccoli. It has been suggested as a promising antioxidant. In this study, the therapeutic effect of sulforaphane in paraquat intoxication was investigated. Methods: Paraquat was administered via the tail vein, after which sulforaphane or a vehicle (4% DMSO) was administered intraperitoneally 15 minutes after paraquat administration. Histological injury, lipid peroxidation, plasma cytokine (IL-6, IL-10), and nitric oxide were measured. In addition, the effect of sulforaphane on survival in paraquat-intoxication was observed. Results: Regarding histological injury, lipid peroxidation, and plasma cytokine and nitric-oxide response, sulforaphane administration showed no protective effects in paraquat-intoxicated rats. Rather, it increased mortality (log rank p=0.03) and caused lipid peroxidation, as well as plasma cytokine and nitric-oxide production, to be increased. Conclusion: Sulforaphane had no therapeutic effect on paraquat-intoxicated rats; rather, it increased mortality.

• Journal of The Korean Society of Clinical Toxicology
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• v.16 no.1
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• pp.9-14
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• 2018

Purpose: Intravenous lipid emulsion (ILE) has been shown to have significant therapeutic effects on calcium channel blocker overdose in animal studies and clinical cases. In this preliminary experiment, we investigated the hemodynamic changes and survival in a rat model of verapamil intoxication. Methods: Fourteen male Sprague-Dawley rats were sedated and treated with ILE or normal saline (control), followed by continuous intravenous infusion of verapamil (20 mg/kg/h). Mean arterial pressure and heart rate of rats were monitored during the infusion. In addition, the total dose of infused verapamil and the duration of survival were measured. Results: Survival was prolonged in the ILE group ($32.43{\pm}5.8min$) relative to the control group ($24.14{\pm}4.3min$) (p=0.01). The cumulative mean lethal dose of verapamil was higher in the ILE group ($4.3{\pm}0.7mg/kg$) than in the control group ($3.2{\pm}0.5mg/kg$; p=0.017). Conclusion: ILE pretreatment prolonged survival and increased the lethal dose in a rat model of verapamil poisoning.

• The Journal of the Korea institute of electronic communication sciences
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• v.15 no.4
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• pp.717-724
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• 2020

Due to the important role played by emotion in human interaction, affective computing is dedicated in trying to understand and regulate emotion through human-aware artificial intelligence. By understanding, emotion mental diseases such as depression, autism, attention deficit hyperactivity disorder, and game addiction will be better managed as they are all associated with emotion. Various studies for emotion recognition have been conducted to solve these problems. In applying machine learning for the emotion recognition, the efforts to reduce the complexity of the algorithm and improve the accuracy are required. In this paper, we investigate emotion Electroencephalogram (EEG) feature reduction and classification using Stack AutoEncoder (SAE) and Long-Short-Term-Memory/Recurrent Neural Networks (LSTM/RNN) classification respectively. The proposed method reduced the complexity of the model and significantly enhance the performance of the classifiers.

• Journal of Acupuncture Research
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• v.27 no.4
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• pp.55-65
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• 2010

목적 : 기존 연구에서 신문혈 자침은 알코올 및 코카인을 자가섭취하는 동물 모델에서 효과적이라는 점이 밝혀졌으며, 또한 모르핀 자가섭취를 억제할 수 있음이 밝혀졌다. 이러한 결과를 바탕으로 본 연구에서는 자침의 효과가 얼마나 지속될 수 있는지 알아보았다. 재료 및 방법 : 체중 270~300g의 수컷 SD계 흰쥐를 이용하였다. 먹이섭취 훈련을 통과한 후 오른쪽 경정맥에 관을 삽입하는 수술을 거쳐, 0.1mg/kg의 모르핀을 매일 1시간, 총 3주 동안 자가섭취 하도록 하였다. 모르핀을 일정하게 섭취한 동물에게는 다음날 침술을 시행하였다. 두 번째 실험에서는 GABAA 및 GABAB 길항제를 자침 30분 전에 투여하여 침술의 효능과 GABA 수용체계 사이의 관계를 검증하였다. 결과 : 모르핀 자가섭취를 억제하는 신문혈 자침의 효과는 매일 비슷하게 나타나지 않았으며, 4일째에는 유의한 효과가 없는 것으로 나타났다. 그러나 5일째와 6일째에는 다시 유의한 효과가 나타나 뒤집어진 U 자형 곡선을 나타내었다. 또한 GABA 수용체의 길항제들은 자침의 효과가 유의하게 나타났을 때 이를 차단하는 결과를 보였다. 결론 : 모르핀 중독 치료에서 침술의 효과는 항상 비슷하게 발휘되는 것이 아니므로 침 치료는 적어도 1주일에 2회 이상 받을 필요가 있다. 아울러 보다 심도 있는 연구를 위하여 뇌신경 체계에 대한 연구가 이루어질 필요가 있는 것으로 사료된다.

• Korean Journal of Social Welfare
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• v.64 no.4
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• pp.209-231
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• 2012

Recently, the many anti- stigma program use the 'mental illness is an illness like any other biogenetic illness' approach. This is based on Weiner's attribution affection theory. However, mental illness is difficult to be applied with attribution affection premise because attributing no blame for mental problem(biogenetic cause) leads to fear and dangerousness. We proposed a modified attribution affection model that explains the relations between biogenetic causal belief and social distance. Our model assumed that attributing personal responsibility for each mental problem leads to anger and social distance. And attributing no blame for mental problem(biogenetic causal belief) reinforces perception of dangerousness and social distance. This study presented typical vignettes of schizophrenia, depression and alcoholism according to the diagnosis criteria of DSM-IV to 768 university students randomly. Path analysis was used to test modified attribution affection model. The major findings are, First our original model modified partially for fit index. So final model assumed that i) The more respondents believed personal responsibility, the more anger, the more anger reaction corresponded closely with more social distance. ii) biogenetic causal beliefs leads to a worsening of dangerousness and perception of dangerousness leads to a increasing of social distance. Second, multi-group analysis was conducted to verify how a modified attribution affection model would be applicable to three groups. The result is that there is no difference among three groups. Finding from this research suggest to change anti-stigma program that use medical model.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.5
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• pp.1257-1269
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• 2010

The internet which is fast spread over all areas of our lives provides us with benefits of efficiency, productivity, and amusement; however, its features as an anonymous and non-face-to-face medium have raised a serious social issue of the collapse of internet ethics due to the abuse of it. Thereupon, the importance of internet ethics education has been highlighted to prevent side effects resulted from the internet and cultivate human-centered internet culture. In this paper, we suggests desirable methods for internet ethics education based on the investigation and analysis of the status of university freshmen's internet ethics. This research conducted a survey and analyzed its result after categorizing the status of internet ethics into the invasion of private information, invasion of intellectual property rights, harmful information, internet communication culture, cyber violence, internet addiction, and internet fraud. And based on the result of analyzing their internet ethics, this paper suggests desirable methods for internet ethics education. Next, internet ethics education was conducted by applying the proposed methods for internet ethics education, and its educational effect was evaluated. According to the result of verifying the educational effect measured statistically, it has proved that the suggested internet ethics education is effective to improve undergraduates' internet ethics.

• Journal of the Korean Society of Food Culture
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• v.25 no.6
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• pp.839-846
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• 2010

This study was designed to investigate the effects of Korean Eucommia ulmodies Oliver tea extract on aluminum administered rats. Forty-eight male Sprague-Dawley rats (100${\pm}$10 g) were divided into the following six groups; control group, 3% E. ulmodies tea extract group, 1,000 and 2,000 ppm aluminum ($Al_2(SO_4)_3$ in distilled water) groups, and 1,000 and 2,000 ppm aluminum plus 3% E. ulmodies tea extract groups. The aluminum content in the rat tissues of the aluminum administered group was lower than that in the rat tissue of the aluminum group administered 3% E. ulmodies tea extract. Asparate aminotransferase and alanine aminotransferase levels increased in the aluminum-administered group but were lower in the 3% E. ulmodies tea extract group. Lactate dehydrogenase was lower in the 3% extract E. ulmodies teaaluminum group than that in the aluminum group. Cholinesterase was higher in the 3% E. ulmodies tea-aluminum group than that in the aluminum group. Plasma renin activity levels increased in the aluminum administration group, compared with the aluminum plus 3% E. ulmodies tea group. Plasma aldosterone levels increased in the aluminum administration group compared with the aluminum plus 3% E. ulmodies tea group. These results suggest that an extract of E. ulmodies tea in water has lowering effects on the accumulation of aluminum. It is believed that the E. ulmodies tea had some protective effects in the aluminum-administered rats, but the mechanisms remain obscure.

• Journal of Music and Human Behavior
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• v.3 no.2
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• pp.29-44
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• 2006

Trust and understanding relationship promoted between a therapist and a client is the basic building block to successful recovery. Its importance is not only pertaining to the music therapy but also to counseling and psychological therapy. Because of its gnificance, broad spectrum of research has been conducted for quite a long time. Historically, researches have been focused on therapists or client's chological variables rather than emotional effects on each other that occur during the therapy session. Recently researchers turned their attention to emotional relationship between a therapist and a client. With recent advances in the field of music and psychological therapy, subsequent study has been conducted to investigate the role that music plays in the therapeutic relationship. For this research, eleven music therapy sessions were conducted for the adult females who are alcoholics. The first three sessions were of group therapy. Fourth to eleventh therapy session was done individually. Throughout the research case-by-case study has been conducted on the basis of the analysis of video and audio taped materials. Analysis depends heavily on its reference from the Amir's music research of 1990, which used Ferrara's seven phases of phenomenological study. Especially, verbal and nonverbal communications were closely analyzed in musical perspective. Research revealed that music and musical instruments act as a mediator between a therapist and a client. By doing so, it protects a therapist from unnecessary negative emotional displacements of a client and creates mutual reliability between a therapist and a client. Here, research suggests that music and musical instrument play a central role in building relationship between a therapist and a client, and it indicates that it has positive effect on treatment.

• Tuberculosis and Respiratory Diseases
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• v.46 no.6
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• pp.775-785
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• 1999

Background : The herbicide paraquat can cause severe lung injury and fibrosis in experimental animals. In this study we have investigated the changes in lung endothelin-1(Et-1) levels and immunohistochemical localization in relation to treatment with cyclophosphamide and methylprednisolone in paraquat induced pulmonary fibrosis in guinea pigs. Material and methods : 29 male Hartley guinea pigs were divided into 4 groups. Group I was normal control. Paraquat was instilled into the lung of guinea pig of group II, III and IV unilaterally. Group II was treated with cyclophosphamide and methylprednisolone. Group III was treated with methlprednisolone. Group IV was not treated. The degree of fibrosis was evaluated by H-E stains and Masson's trichrome stains and cell activity was assessed by Et-1 immunohistochemical stains. Statistical evaluation was performed using the Kruskawallis oneway analysis. Results : Paraquat induced an increase in numbers of fibroblasts and total amount of lung collagen in Group IV compared to the normal controls. There was no significant difference in total numbers of fibroblasts between any of paraquat instilled groups, but there was significant increase in total amount of collagen in Group IV compared to group II and III (p<0.05). The treatment of cyclophosphamide and methyprednisolone suppressed the growths of both fibroblasts and collagen, but this suppression was stastically significant only in the case of collagen Et-1 immunoreactivities of bronchial epithelium, type II pneumocytes, endothelial cells and fibroblast in group II and III were decreased compared to those in group IV. Conclusion : These results demonstrate that Et-1 is an important contributing factor in the pathogenesis of pulmonary fibrosis. Et-1 is synthesized and released by bronchial epithelium, Type II pneumocyte, endothelial cells, alveolar macrophages and fibroblasts. Especially they are associated with alveolar macrophage and fibroblasts. We conclude that combined therapy of cyclophosphamide and methylprednisolone are more effective in the control of Et-1 expression and collagen deposition.