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http://dx.doi.org/10.7318/KJFC.2010.25.6.839

Effects of Eucommia ulmodies Oliver Tea Extract on aluminum Accumulation Rate and Tissue Function in Aluminum-administered Rats  

Han, Sung-Hee (Department of Food & Nutrition, Wonkwang Health Science Unuversity)
Publication Information
Journal of the Korean Society of Food Culture / v.25, no.6, 2010 , pp. 839-846 More about this Journal
Abstract
This study was designed to investigate the effects of Korean Eucommia ulmodies Oliver tea extract on aluminum administered rats. Forty-eight male Sprague-Dawley rats (100${\pm}$10 g) were divided into the following six groups; control group, 3% E. ulmodies tea extract group, 1,000 and 2,000 ppm aluminum ($Al_2(SO_4)_3$ in distilled water) groups, and 1,000 and 2,000 ppm aluminum plus 3% E. ulmodies tea extract groups. The aluminum content in the rat tissues of the aluminum administered group was lower than that in the rat tissue of the aluminum group administered 3% E. ulmodies tea extract. Asparate aminotransferase and alanine aminotransferase levels increased in the aluminum-administered group but were lower in the 3% E. ulmodies tea extract group. Lactate dehydrogenase was lower in the 3% extract E. ulmodies teaaluminum group than that in the aluminum group. Cholinesterase was higher in the 3% E. ulmodies tea-aluminum group than that in the aluminum group. Plasma renin activity levels increased in the aluminum administration group, compared with the aluminum plus 3% E. ulmodies tea group. Plasma aldosterone levels increased in the aluminum administration group compared with the aluminum plus 3% E. ulmodies tea group. These results suggest that an extract of E. ulmodies tea in water has lowering effects on the accumulation of aluminum. It is believed that the E. ulmodies tea had some protective effects in the aluminum-administered rats, but the mechanisms remain obscure.
Keywords
eucommia ulmodie oliver tea extract group; aluminum; AST; ALT; LDH; ChEase; renin; aldosterone;
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1 喬木敬次郞, 木村正廉, 原田正敏, 大土家公男. 1982. 和漢藥物學, 東京, 南山堂. p 159
2 Amador E, Dorfman E, Wacker WE. 1963. Serum lactic dehydrogenase activity an analytical assessment of current assays. Clin Chem, 8(12):391-399
3 Armstrong RA, Winsper SJ, Blair JA. 1996. Aluminum and alzherimer's disease review of possible payhogenic mechanisms. Dementia, 7(1):1-9
4 Aksari P, Stoppe G. 1996. Risk factors in alzheimer's dementia. Fortschritteder Neurologie-psychiartrie, 64(11):425-432   DOI   ScienceOn
5 Brenner BM, Rector FC. 1981. The kidney. Saunders, pp. 371-399, 650-679:723, 741
6 Bergmeyer HU. 1995. Methods of enzymatic analysis. Verlag chemic, Academic press weinheim, 6(1):20-28
7 Berlyne, NC, Yagil. R, Ben Ari J, Weinberger G, Knopf E, Danovith GM. 1972. Aluminum toxicity in rats. Lancet, 299(7750): 546-567
8 Bioshop NJ, Morley R, Day JP, Lucas A. 1997. Aluminum neurotoxicity in preterm infants receving intravenous-feeding solution. N Engl J Med, 336(22):1557-1561   DOI   ScienceOn
9 Bowen DM, Benren JS, Allen SJ, Good hardt MJ. 1983. Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzherimer's disease. J Neurochem, 41(1):266-272   DOI
10 Candy JM, Oakley AE, Klinowski J, Carpenter TA, Perry RH, Attack JR, Perry EK, Blessed G, Fairbrain A, Edwawdson JA. 1986. Aluminosilicates and sensile plague formation in Alzherimer's disease. Lancet, 327(8477):354-356   DOI   ScienceOn
11 Cho KW, Malvin RL. 1979. Renin inactivation during in vitro. Experimental Am J Physiol, 236(4):501-504
12 Cho KW, Kim SH. 1982. Factors affecting the relationship between renal renin activity and plasma renin activity. Kor J Physiol, 16(1):63-69
13 Cho KW, Kim SH, Koch GY. 1987. Radioimmunoassay and characterization of renin-angiotensin system in the fresh water turtle. J Exp Zool, 242(3):255-262   DOI
14 Cho KW, Kim SH, Koh GY, Seul KH, Huh KS, Chu D, Rap NS, Moon HB, Kim KK, Kook YJ. 1989. Plasma concentration of atrial natriuretic peptide in different phase of korean hemmorrhagic fever. Nephron, 51(2):215-219   DOI
15 Choi BS, Park YJ, Kweon IH, Hong YP, Park JD. 2002. Reference values of mercury in liver and kidney of korean. Korean J Environ Toxicol, 17(2):119-115   DOI   ScienceOn
16 Chung Y, Hwanf MS, Yung GY, Jo SJ. 1999. Health risk assessment of lead exposure through multi-pathways in korea. Korean J Environ Toxicol, 14(4):203-216   DOI
17 Deloncle R, Huguet F, Babin P, Fermandez B, Quellard N, Guillard O. 1999. Chronic administration of aluminum L-glutamate in young mature rats, effects in iron levels and lipid peroxidation in selected brain areas. Toxicology letters, 10(1):65-73
18 El-Maraghy SA, Gad MZ, Fahim AT, Hamdy MA. 2001. Effects of cadmiun and aluminum intake in the antioxidant state and lipid peroxidation in rat tissues. J Biochem Molecular toxicoligy, 15(2):207-214   DOI
19 Ganje JJ, Page AL. 1976. Rapid acid dissoulation of plant tissue for cadium determination by atomic absorption spectrophotometry. At Absorpt Newsl, 131(37):108-110
20 Ginsberg AL. 1970. Very high levels of SGOT and LDH in patients with extrahepatic billiary tract obstruction. J Amer Dig Dis, 15(9):803-805   DOI   ScienceOn
21 Goodfriend TL, L Levine, Fasma GD. 1964. Antibodies to bradykinin and angiotensin. A use of carbodiimide in immunololgy. Science, 144(2):1344-1346   DOI
22 Han SH, Shin MK. 2005. Effects of water in extracts of pueraria radix on serum enzymes activities in aluminumadministerates. J Korean Soc Food Culture, 20(1):113-122   과학기술학회마을
23 Hsieh CI, Yen GC. 2000. Antioxidant actions of du-zhong (Eucommia ulmoides oliver) toward oxidative damage in biomoleucules. Life Sci, 66(5):1387-1400   DOI   ScienceOn
24 John MC,Quinlan GJ, Clark I, Halliwell B. 1985. Aluminum salts accerate peroxidation of menbrane lipids stimulated by iron salts. Biochem Biopaths Acta, 835(3):441-447   DOI   ScienceOn
25 Jeffery EH, Abreo K, Burgess E, Cannata J, Greger LJ. 1996. Systemic aluminum toxicity; effects on bone, hematopoietic tissue, and kidney. J Toxicology environmental health, 48(6):649-665   DOI   ScienceOn
26 Karmen A. 1955. A note on the spectrophtometric assay of glutamic oxaloacetic transaminase in human blood serum. J Clinic Invest, 95(1):131-139
27 Krischbaum BB, Werth AC. 1989. Acute aluminum toxocity associated with oral citrate and aluminum-containg antacids. American Journal of Medical sciences, 297(1):9-11   DOI   ScienceOn
28 Landsberg JP, Mc Donald B, Watt F. 1992. Absence of aluminum in neuritic plague cores in Alzherimer's disease. N ature, 360(1):65-68   DOI
29 Lee IK, Kim JG. 2000. Effects of extract of eucommia ulmoides oliver on the reduction of lead and cadmium in organs rats. J Korean Public Health Assoc, 26(1):22-28
30 Lee HS. 1992. Analysis of aluminum concentration in serum and phospholipid composition and catecholamin concentration in the brain of rats feed aluminum in drinking water. Dept of food. sukmong univ.
31 Marquis & Black. 1984. Aluminum activation and inactivation of bovine caudate acetylcholinerserase. Bull Environ Contam Toxicol, 32(1):704-710   DOI   ScienceOn
32 Neill D, Leake A, Hunghes D, Keith AB, Taylor GA, Allsop D, Rima BK, Morris C, Candy JM, Edwardson JA. 1996. Effect of aluminum on expression and processing of amyloid precursor protein. J of Neuroscience Reserach, 46(4):395-403   DOI   ScienceOn
33 Metori K, Furutsu M, Takahashi S. 1997. The preventive effect of ginseng with Du-zhong leaf on protein metabolism in aging. Biol Pharm Bull, 20(3):237-242   DOI   ScienceOn
34 Nagasawa H, Mitamura T, Sakamoto S, Yamamoto K. 1995. Effects of lycopene on spontaneous mammary tumour development in SHN virgin mice. Anticancer Res, 15(4):1173-1178
35 Nakamura T, Nakazawa Y, Onizuka S, Satoh S, Chiba A, Sekihashi K, Miura A, Yasugahara N, Sasaki Y. 1997. Antimutagenicity of Tochu tea; 1. The clastogen-suppressing effect of Tochu tea in CHO cells and mice. Mut Res, 38(1):7-20
36 Park SA, Choi MS, Jung UJ, Kim MJ, Kim DJ, Park HM, Park YB, Lee MK. 2006. Eucommia ulmoides oliver leaf extractincreases endogenous antioxidant activity in type 2 diabetic mice. J Med Food, 9(3):472-479
37 Reitman S, Frankel S. 1957. A Colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Amer J Clin Pathol, 28(1):56-60   DOI
38 Rhee SJ, Hung PC. 1989. Metallothionein accumulation in CHO, cd cells in response to lead treatment. Chem Biol Interations, 72(3):347-361   DOI   ScienceOn
39 Sasaki Y, Satoh, S, Chiba A, Murakami M, Sekihashi K, Tanaka M, Moribayashi N, Kudou C, Hara Y, Nakazawa Y, Nakamura T, Onizuka O. 1996. Antimutagenicity of Tochu tea 2. Suppressing effect of tochu tea. Mut Res, 371(3):203-214   DOI
40 Salib E Hillier V. 1996. Acase-control study of alzherimer's disease and aluminum occupation. Brith J Psychiatry, 168(2):244-249   DOI   ScienceOn
41 Sedman AB, Wikening GN, Bradely PD, Warady BA, Lum GM, Alfrey AC. 1984. Encephalopathy in childhood secondary to aluminum toxicity. Journal of pediatrics, 105(5):835-836
42 Yoshida H, Yoshimasu F. 1996. Alzherimer's disease and trace elements. Nippon rinsho Japanese. J Clin Med, 54(1):111- 116
43 Sealey JE, Laragh JH. 1973. Searching out low renin patients limitation of some commonly used methods. Am J Med, 55(3):303-314   DOI   ScienceOn
44 Wroblewski F, LaDue JS. 1955. Lactic dehydrogenase activity in blood. Proc Soc Exper Biol Med, 90(1):210-213   DOI