• Journal of the Korean Medical Association
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• v.61 no.12
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• pp.765-775
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• 2018

With growing interest in novel digital healthcare devices, such as artificial intelligence (AI) software for medical diagnosis and prediction, and their potential impacts on healthcare, discussions have taken place regarding the regulatory approval, coverage, and clinical implementation of these devices. Despite their potential, 'digital exceptionalism' (i.e., skipping the rigorous clinical validation of such digital tools) is creating significant concerns for patients and healthcare stakeholders. This white paper presents the positions of the Korean Society of Radiology, a leader in medical imaging and digital medicine, on the clinical validation, regulatory approval, coverage decisions, and clinical implementation of novel digital healthcare devices, especially AI software for medical diagnosis and prediction, and explains the scientific principles underlying those positions. Mere regulatory approval by the Food and Drug Administration of Korea, the United States, or other countries should be distinguished from coverage decisions and widespread clinical implementation, as regulatory approval only indicates that a digital tool is allowed for use in patients, not that the device is beneficial or recommended for patient care. Coverage or widespread clinical adoption of AI software tools should require a thorough clinical validation of safety, high accuracy proven by robust external validation, documented benefits for patient outcomes, and cost-effectiveness. The Korean Society of Radiology puts patients first when considering novel digital healthcare tools, and as an impartial professional organization that follows scientific principles and evidence, strives to provide correct information to the public, make reasonable policy suggestions, and build collaborative partnerships with industry and government for the good of our patients.

• Korean Journal of Heritage: History & Science
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• v.47 no.4
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• pp.48-57
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• 2014

More than 30 lead beads have been excavated from buddhist temples and sites but the production times are unknown the origin. The aim of this study is to estimate manufacturing technique and provenance of 11 beads through the chemical composition and isotope analysis. Results shows that the lead beads are composed of high-purity lead and cast using for 2 semicircle moulds. Furthermore, 11 lead beads are similar in size, chemical composition and casting methods. Lead isotope analysis data suggest that the provenance of lead beads are not Korea peninsula. Also it is estimated that 11 lead beads were divided in 2 groups considering the time and places of production. The future works will be executed additional scientific analysis and historical background due to confirm the manufacturing system and provenance.

• Korean Journal of Heritage: History & Science
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• v.39
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• pp.5-38
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• 2006

Although in Korea there are only three examples of wooden coffins being found in burial mounds - from the Daho-ri, Songhyun-dong, and Munyung tombs, in Japan data on the shape and structure of wooden coffins from the Gofun era is relatively abundant. The wooden coffins of the Gofun era of Japan can be classified into either the dugout log style or the combined boards style according to their method of manufacture. They can also be divided by shape, into such categories as the boat shape, the split bamboo shape, the box shape, and so on. The box shape category can be further divided into the assembled type and the nailed type, according to how the boards are put together. Japanese Umbrella Pine (Sciadopitys verticillata) was favored as coffin-wood in all ages, but during the later Gofun era easily obtained woods such as the Japanese cedar (Cryptomeria japonica) or the Hinoki Falsecypress (Chamaecyparis obtusa) were also used. The coffins found at Daho-ri and Songhyun-dong are similar to the Japanese dugout log style in shape and manufacture, while the king's and queen's coffins excavated at Munyung Tomb are seen to have had direct influence on the appearance of nailed coffins Japan. The coffin in Songhyun-dong 7th mound was originally a dugout log boat. It was probably used for practical reasons such as the bugproof, anti-corrosion qualities of camphor wood, not because of ideological reasons such as in a boat burial (in which the boat takes the deceased to the after world). Because the Changnyong region is inland, where camphor trees do not grow, using an already existing boat may have been the only way to procure a camphor-wood coffin. From historical circumstances, it may be inferred that the camphor trees were imported into Korea from Japan, between which there was much cultural exchange.

• The Korean Journal of Archival Studies
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• no.44
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• pp.155-197
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• 2015

Disaster of Sewol took place in one year. Meanwhile, the victim's family and the call time record academics have tried to record it. Ansan activists have moved to objectives such as civil records committee also pivotal. The citizens committee under the dictation recording oral history team has a diverse group of people associated with the time issue. bereaved families were collected from the oral as well as volunteers, religious personnel, activists, Ansan citizens and various people. Disasters around the world is also an important event to remember and honor the people together, and one of the most effective means to record There it is establishing an oral history archive. Does not leave a lot of nature history of sudden disasters that occur, as well as a tribute record dictation telling people of diverse perspectives on events helps a lot closer to the reality of the event. Erected in the National September 11 Memorial Museum to honor the Sept. 11 attacks and provide a variety of programs to chaerok dictation of the people involved with 9/11. To remember the 2013 Boston Marathon bombing 'Our Marathon' of crowdsourcing digital archive was built. In the archives of the local universities and institutions were created to collaborate actively and gathering oral history. Pan Am Flight 103 pieces terror has established an archive from Syracuse University. Here, neither graduates, faculty, and to the victim's family and friends gather and oral hitory. Disaster-related Sewol neither should be able to be used as in the case of foreign well, and it should continue to honor the victims of the collection. It also ought to occasion again to avoid this disaster on earth.

• The Korean Journal of Archival Studies
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• no.39
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• pp.101-138
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• 2014

This study examined the influence and meaning of SNS as the hot topic of our time from the archival perspective and also studied the 'SNS records management'. The many users mean a high accessibility and utilization of SNS, which increase the influence and value of SNS as a record. Politically, SNS is a tool that strengthens the communication among the voters, politicians and the public while economically, it is a window to accept the complaints of the customers and a marketing tool. In addition, the voices of social minorities are also recorded unlike in the traditional media, which makes the SNS record a method to gain the social variety and diversity. SNS is a place of formation of collective memory and collective memory itself. Furthermore, it can play the role of public sphere. It also is a place for generation of 'big data' in an archival sense. In addition, this study has classified the SNS records management into primary and secondary management that include record management entities, subjects, periods, methods, and causes. This study analyzed the history, status, and the meaning of SNS to assess the values and meanings as the preliminary study for the future SNS record management studies.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.12
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• pp.758-764
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• 2018

This study was performed to investigate the effects of Occupation based Reminiscence therapy on cognitive function, depression, and quality of life in elderly patients with mild dementia. Thirty-one elderly patients with mild dementia underwent Occupation based Reminiscence therapy for 40 minutes per session, once weekly, for 8 weeks. Montreal Cognitive Assessment Korean Version (MoCA-K), Short Form of Geriatric Depression Scale-Korean Version (SGDS-K), and Geriatric Quality of Life-Dementia (GQOL-D) were used to measure cognitive function, depression level, and quality of life, respectively. Mean MoCA-K score increased from $14.62{\pm}5.07$ before intervention to $16.88{\pm}4.55$ after intervention; mean SGDS-K score decreased from $7.28{\pm}4.28$ to $6.10{\pm}4.09$, and mean GQOL-D score increased from $26.05{\pm}5.45$ to $28.55{\pm}5.74$. Furthermore, these positive changes were all statistically significant. Based on the results of this study, it was concluded Occupation based Reminiscence therapy may positively affect cognitive function, depression, and quality of life in elderly patients with mild dementia.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.6
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• pp.201-209
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• 2019

This study aimed to find out the morphological evolution process for future vision of world smart city. The contents and methods of study was divided and compared by 4 continents and Korea focused on the convergence numbers of ET and IT in smart city and did correlation analysis and analysis of convergence number in device/technology by periods. The analysis materials were 32 cases of smart city in whole world and times were 4 periods. The results of study were listed below. First, the smart city in period 1 was morphological evolutions preserved environment and kept natural form of existing city and filled up device/technology. Second, the smart city in period 2 was morphological evolutions through ET-centric development. Third, the smart city in period 3 was morphological evolutions through advancement of ET and device/technology related to production of energy. Forth, the smart city in period 4 was morphological evolutions fusing, dissipating and creating new ET and IT through the advancement process of all technologies. In conclusion, morphological evolution of smart city will change systematic city structure of convergence form, not each discriminating development between ET and IT, and the forming of smart city will be evolved by repetitive convergence process of technologies continually.

• Korean Chemical Engineering Research
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• v.59 no.4
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• pp.487-492
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• 2021

In this study, the electrochemical properties of pitch coated silicon sheets/graphite anode materials were investigated. Using NaCl as a template, silicon sheets were prepared through the stöber method and the magnesiothermic reduction methode. In order to synthesize the anode composite, the silicon sheets and graphite were combined with SDBS. The pitch coated silicon sheets/graphite was synthesized using THF as a solvent for the anode material composite. The physical properties of the prepared anode composites were analysed by XRD, SEM, EDS and TGA. The electrochemical performances of the prepared anode composites were performed by the current charge/discharge, rate performance, cyclic voltammetry and EIS tests in the electrolyte LiPF₆ dissolved solvents (EC:DMC:EMC=1:1:1 vol%). As the silicon composition of silicon sheets/graphite composite material increased, the discharge capacity also increased, but the cycle stability tended to decrease. The anode material of pitch coated silicon sheets/graphite composite (silicon sheets:graphite=3:7 weight ratio) showed the initial discharge capacity of 1228.8 mAh/g and the capacity retention ratio of 77% after 50 cycles. From these results, it was found that the cycle stability of pitch coated silicon sheets/graphite was improved.

• Journal of Korea Foundry Society
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• v.41 no.2
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• pp.127-131
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• 2021

Based on its good compatibility with high-temperature environments, the Ti-48Al-2Cr-2Nb alloy is used for high-temperature materials of industrial equipment. In this study, a Ti-48Al-2Cr-2Nb alloy turbocharger turbine wheel was fabricated by a vacuum centrifugal casting method. The conditions that prevent misrun defects of the turbocharger turbine wheel blade from centrifugal casting using alumina molds were investigated. The microstructure of the alloy prepared by vacuum centrifugal casting was studied by means of optical microscopy (OM), with a micro-Vickers hardness analyzer (HV), by X-ray diffraction (XRD) and by SEM-EDS. The HV and SEM-EDS examinations of the as-cast Ti-48Al-2Cr-2Nb alloy showed that the thickness of the oxide layer (α-case) was typically less than 50 ㎛. At a high preheating temperature of 1,100℃, a moderate RPM of 260, and with an alumina mold with a large gate size, there were almost no misrun defects. Therefore, it was confirmed that a Ti-48Al-2Cr-2Nb alloy turbocharger turbine wheel with fewer misrun defects could be achieved through a high preheating temperature, a moderate RPM, a large gate size and an alumina mold to suppress the formation of alpha-case components.

• Proceedings of the Plant Resources Society of Korea Conference
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• 2019.10a
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• pp.5-5
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• 2019

DMZ는 살아있는 생물다양성의 보고로 지난 60여년동안 자연적으로 재생이 일어나고 환경적인 강제 보존 영향으로 높은 생태학적인 가치가 유지되고 있으며, 최근에는 남북교류에 대한 활발한 의지로 DMZ생태자원의 남북공동활용 방안에 대한 이슈가 급부상하고 있다. 이에 본 연구진은 3년전부터 DMZ에서 자생하는 식물에 대한 조사를 진행하여 총 200여종 이상의 자생식물의 표본과 추출물들을 보유하고 있으며, 이 추출물들을 활용 in vitro 와 in vivo 평가를 통해 비임상 평가에서 유효한 효과를 나타내는 후보물질들을 다수 찾아낼 수 있었다. 그 중 조팝나무(Spiraea prunifolia var. simpliciflora)는 쌍떡잎식물 장미과에 속하는 낙엽활엽관목으로 동북아시아 지역에 널리 분포되며 우리나라에서는 중부지방에 주로 서식한다고 알려져 있다. 예로부터 해열 및 소염, 신경통완화 치료등에 이용해왔다고 알려져 있으며 그 속에는 다양한 terpenoids, flavonoid 및 phenolic 화합물이 다량 함유되어 있다고 알려져 있다. 본 연구에서는 조팝나무 추출물을 이용하여 전구지방세포에서의 지방세포분화 억제 및 관련 유전자들의 활성을 확인한 후 고지방식이로 유도된 high-fat diet mouse model을 이용하여 체지방 감소 및 내장지방감소, 간 조직내의 지방량 감소등을 확인하였으며, 혈액분석을 통해 총콜레스테롤과 고중성지방등 동맥경화와 심혈관계 질환을 유도시킬수 있는 지표들에서 억제 활성도 확인하였다. 특히 내장 지방의 경우는 Micro-CT를 통해 정밀한 분석을 진행하였고, 체지방뿐만 아니라 전체 체중감소도 나타나는 것을 확인하였다. 현재 실험을 통해 적출된 간 조직과 지방조직을 이용하여 항 비만 활성의 작용기전을 지속적으로 확인하고 있으며, 이 결과는 국제적인 연구저널에 보고되어 향후 체지방 감소 또는 항 비만 치료제로 개발되는 비임상 연구자료로 활용될 계획이다. 이미 조팝나무에 대한 연구결과는 특허로 출원이 완료되어 PCT출원까지 진행중에 있으며 개별인정형 건강기능식품 개발 기업에 기술이전이 될 예정이다. 또한 원활한 원료 수급을 위해 기초단체 소속 농업기술센터와 원료 재배 및 대량 수급에 관한 논의를 마친 상태로 접경지역 근처 농가소득 증대로도 이어지는 제품화 사례이기도 하다. 이는 접경지역에서 자생하는 원료의 활성을 과학적으로 검증하여 기업과의 연계를 통해 기초시군 단체의 농가 소득과도 연계한 우수한 제품개발 사례로 향후에도 이와 같은 연구성과가 지속적으로 도출되기를 기대해본다.