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Development of an In Vitro Pigmented Skin Model to Evaluate the Effectiveness of Whitening Functional Cosmetic Ingredients (미백 기능성 화장품 원료의 유효성 평가를 위한 In Vitro 색소화피부모델 개발)

  • Kim, Seolyeong;Lee, Geonhee;Gwak, Eun Ji;Kim, Su Ji;Lee, Su Hyon;Lim, Kyung-Min
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.47 no.4
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    • pp.297-304
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    • 2021
  • In this study, we prepared a pigmented skin model, KeraSkin-MTM for the in vitro evaluation of whitening agents. For the purpose of complementing the existing mono-layer cell culture testing method, KeraSkin-MTM was produced through the co-culture of human skin-derived keratinocytes and melanocytes. The efficacy of four well-known whitening agents (arbutin, ascorbic acid, kojic acid, niacinamide) was evaluated in KeraSkin-MTM in order to assess its usefulness in assessing whitening efficacy. As a result, it was possible to observe additional details such as the distribution of melanin granules and melanin capping in each skin layer through KeraSkin-MTM, which was previously difficult to assess in the traditional 2D cell culture system. In addition, quantification through image analysis of KeraSkin-MTM allowed for a statistical analysis of the whitening effects. These results suggest that the KeraSkin-MTM can be used as a new evaluation method of evaluating whitening efficacy, as well as complement the traditional total melanin content and tyrosinase inhibition assays.

Electrochemical Deposition Characteristics of Ca2+ on Cu Wire Electrode in CaCl2 Molten Salt (CaCl2 용융염에서 Ca2+의 Cu 전극에 대한 전기화학적 증착 특성평가)

  • Hwang, Dong Wook;Lee, Jong Hyeon;Jeong, Sang Mun
    • Korean Chemical Engineering Research
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    • v.60 no.2
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    • pp.175-183
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    • 2022
  • With the expansion of the automobile market, the demand for Nd as an essential rare earth material for automobile motors is rapidly increasing. Research on the calcio-thermic reduction process between Nd2O3 and calcium-based alloys has been extensively studied in order to manufacture Nd. In this study, Ca-Cu, as a reducing for Nd2O3, was prepared by electrolysis in CaCl2 molten salt. Cu wire and graphite were employed as a working electrode and a counter electrode for electrolysis reaction, respectively. The reference electrode was manufactured by putting Ag wire in a mixture of AgCl and CaCl2 at a ratio of 1:99 mol%. The cyclic voltammetry results showed that the deposition of Ca2+ on the surface of working electrode was observed from a potential of -1.8 V, and the reduction potential of Ca2+ decreased as the reaction temperature increased. The diffusion coefficient of Ca2+ calculated by the chronoamperometry experiment was found to be 5.4(±6.8)×10-6 cm2/s. In addition, Ca-Cu liquid alloy was prepared by applying a constant potential to Cu electrodes. The element ratio of Ca-Cu alloy formed by applying a potential of -2.0 V was found to Ca:Cu=1:4.

A Fundamental Study on Shearing/Bonding Characteristics of Interface Between Rock Mass and Backfills in Mine Openings (폐광산 채움재와 암반 경계부의 전단 및 접합특성에 관한 기초 연구)

  • Kim, Byung-Ryeol;Lee, Hyeon-woo;Kim, Young-Jin;Cho, Kye-Hong;Choi, Sung-Oong
    • Tunnel and Underground Space
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    • v.31 no.6
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    • pp.623-646
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    • 2021
  • As the demand for electric power increases with acceleration of electrification at home and abroad, the needs for coal-fired electrical power plant are accordingly increased. However, these coal-fired electrical power plants induce also many environmental problems such as increase of air pollutants, increase of possibility of land contamination by reclamation of coal ash, even though these power plants have a good economical efficiency. In case of a by-product of coal-fired electrical power plants, only 70% of them are recycled and the remaining 30% of by-product are fully buried in surrounding ground. Consequently, this study deals with coal ash backfilling mechanism in abandoned mine openings for the purposes of increasing the coal ash recycling rate as well as securing the mine area stability. In order to analyze the backfill and ground reinforcement by interaction between rock mass and backfills, the copying samples of discontinuous surface with different roughnesses were produced for bond strength tests and direct shear tests. And statistical analysis was also conducted to decide the characteristics of bond and shear behavior with joint roughness and their curing day. Numerical simulations were also analyzed for examining the effect of interface behavior on ground stability.

Application of Dimensional Expansion and Reduction to Earthquake Catalog for Machine Learning Analysis (기계학습 분석을 위한 차원 확장과 차원 축소가 적용된 지진 카탈로그)

  • Jang, Jinsu;So, Byung-Dal
    • The Journal of Engineering Geology
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    • v.32 no.3
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    • pp.377-388
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    • 2022
  • Recently, several studies have utilized machine learning to efficiently and accurately analyze seismic data that are exponentially increasing. In this study, we expand earthquake information such as occurrence time, hypocentral location, and magnitude to produce a dataset for applying to machine learning, reducing the dimension of the expended data into dominant features through principal component analysis. The dimensional extended data comprises statistics of the earthquake information from the Global Centroid Moment Tensor catalog containing 36,699 seismic events. We perform data preprocessing using standard and max-min scaling and extract dominant features with principal components analysis from the scaled dataset. The scaling methods significantly reduced the deviation of feature values caused by different units. Among them, the standard scaling method transforms the median of each feature with a smaller deviation than other scaling methods. The six principal components extracted from the non-scaled dataset explain 99% of the original data. The sixteen principal components from the datasets, which are applied with standardization or max-min scaling, reconstruct 98% of the original datasets. These results indicate that more principal components are needed to preserve original data information with even distributed feature values. We propose a data processing method for efficient and accurate machine learning model to analyze the relationship between seismic data and seismic behavior.

Nanofibers Comprising Mo2C/Mo2N Nanoparticles and Reduced Graphene Oxide as Functional Interlayers for Lithium-Sulfur Batteries (Mo2C/Mo2N 나노 입자와 환원된 그래핀 옥사이드가 복합된 나노 섬유 중간층이 적용된 리튬-황 전지)

  • Lee, Jae Seob;Yang, Ji Hoon;Cho, Jung Sang
    • Korean Chemical Engineering Research
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    • v.60 no.4
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    • pp.574-581
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    • 2022
  • Nanofibers comprising reduced graphene oxide (rGO) and Mo2C/Mo2N nanoparticles (Mo2C/Mo2N rGO NFs) were prepared for a functional interlayer of Li-S batteries (LSBs). The well-dispersed Mo2C and Mo2N nanoparticles in the nanofiber structure served as active polar sites for efficient immobilization of dissolved lithium polysulfide. The rGO nanosheets in the structure also provide conductive channels for fast ion/electron transport during charging-discharging and ensured reuse of lithium polysulfide during redox reactions through a fast charge transfer process. As a result, the cell assembled with Mo2C/Mo2N rGO NFs-coated separator and pure sulfur electrode (70 wt% of sulfur content and 2.1 mg cm-2 of sulfur loading) showed a stable discharge capacity of 476 mA h g-1 after 400 charge-discharge cycles at 0.1 C. Furthermore, it exhibited a discharge capacity of 574 mA h g-1 even at a high current density of 1.0 C. Therefore, we believe that the proposed unique nanostructure synthesis strategy could provide new insights into the development of sustainable and highly conductive polar materials as functional interlayers for high performance LSBs.

Exploring the Potential of Podcasts in Flower Design Industry (플라워디자인 산업 활성화를 위한 팟캐스트 콘텐츠의 가능성 연구)

  • Yang, Dongbok
    • Journal of the Korean Society of Floral Art and Design
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    • no.44
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    • pp.75-100
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    • 2021
  • The purpose of this study is to explore ways in which the flower design industry can utilize podcasts that are rapidly growing in recent years. I selected foreign flower podcasts that are ranked on the global podcast chart, and examined the genre, content, components, show hosts and etc. By analyzing the characteristics of the podcast, the type of communication between the host and the audience, the audience interaction, the industry connection, and the media expansion strategy, I tried to derive the possibility of the flower podcast in Korea. As a result of analyzing foreign flower podcasts, podcasters built listener communities based on their rich experience and knowledge through podcasts and used them for education and marketing. They acted as leaders in the industry or led public opinion such as the sustainable flower industry. Podcast shows were repurposed as various content and used to spread flower design culture. In Korea, flower podcasts can be the basis for the formation of a community related to the flower design industry. Flower design experts can use podcasts as a source asset for various content. Listeners within the industry can get hands-on knowledge about the business from flower podcasts. The popular flower podcast will contribute to the vitalization of flower design culture and industry. Flower podcasts can be a starting point to actively cope with the era of personal media.

Evaluation for the Manufacturing Characteristics and Thermal Conductivity of Engineering Scale Bentonite-Sand Buffer Blocks (공학규모 벤토나이트-모래 완충재 블록의 성형특성 및 열전도도 평가)

  • Lee, Deuk-Hwan;Yoon, Seok;Kim, Jin-Seop;Lee, Gi-Jun;Kim, Ji-Won;Kim, Min-Jun
    • Journal of the Korean Geotechnical Society
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    • v.38 no.12
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    • pp.113-123
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    • 2022
  • The required density relationship according to the press pressure of the floating die method and the homogeneity of the density distribution in the buffer block was evaluated to analyze the manufacturing characteristics of engineering scale bentonite-sand buffer blocks. In addition, the thermal conductivity was measured and compared with that of the pure bentonite buffer block to evaluate the level of thermal conductivity performance improvement of the bentonite-sand buffer material. As a result, it was confirmed that the standard deviation of dry density decreased to 0.011 and showed a homogeneous density distribution under the condition of press pressure greater than 400 kg/cm2. Furthermore, as a result of the thermal conductivity test, the thermal conductivity of the buffer with optimum moisture content conditions was 1.345 and 1.261 W/(m·K) under the press pressure of 400 and 600 kg/cm2, respectively. It increased by 16.1% and 11.0% compared to the pure bentonite buffer material. Based on the results of this study, it is judged that it can be used as fundamental data for manufacturing a homogeneous bentonite-sand buffer block on an engineering scale.

Optimal Design for Weight Reduction of Rotorcraft Shaft System (회전익기의 축계 경량화를 위한 최적설계)

  • Kim, Jaeseung;Moon, Sanggon;Han, Jeongwoo;Lee, Geun-Ho;Kim, Min-Geun
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.35 no.4
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    • pp.243-248
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    • 2022
  • Weight optimization was performed for a rotorcraft shaft system using one-dimensional Euler-Bernoulli beam elements. Torsion, shaft support stiffness such as bearings, flange mass are all considered. To guarantee structural dynamic stability, eigenvalue analysis was performed to avoid critical speed and tooth mesh excitation form the gearbox. The weight optimization was performed by adjusting the thickness and radius while the length of the shaft was fixed, and the optimization process was divided into two stages. In the first, the weight is optimized with the torsional strength constraint. In the second, the difference between the primary mode of shaft and the critical speed is maximized so that the primary mode of the shaft can avoid the critical speed while the constraint on the torsional strength of the shaft is satisfied according to the standard for shaft system stability (AMC P 706-201, 1974). The proposed method was verified by comparing the results of the optimal design using the given one-dimensional beam elements with the stress results of the 3D finite element and the actual manufactured shaft.

Assessment of the Coupled Electric-Thermal Numerical Model for Microwave Sintering of KLS-1 (한국형 인공월면토(KLS-1) 마이크로파 소결을 위한 전기장-열 연계해석 모델 평가)

  • Jin, Hyunwoo;Go, Gyu-Hyun;Lee, Jangguen;Shin, Hyu-Soung;Kim, Young-Jae
    • Journal of the Korean Geotechnical Society
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    • v.38 no.5
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    • pp.35-46
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    • 2022
  • The in-situ resource utilization (ISRU) for sustainable lunar surface and deep space explorations has recently gained attention. Also, research on the development of construction material preparation technology using lunar regolith is in progress. Microwave sintering technology for construction material preparation does not require a binder and is energy efficient. This study applies microwave sintering technology to KLS-1, a Korean lunar simulant. It is crucial to secure the homogeneity to produce a sintered specimen for construction material. Therefore, understanding the interactions between microwaves, cavities, and raw materials is required. Using a numerical model in terms of efficient assessment of several cases and establishment of equipment operating conditions is a very efficient approach. Therefore, this study also proposes and verifies a coupled electric-thermal numerical model through cross-validation and comparison with experimental results. The numerical model proposed in this study will be used to present an efficient method for producing construction material using microwave sintering technology.

Characteristics of Dynamic Shear Behavior of Pile-Soil Interface Considering pH Conditions of Groundwater (지하수 pH조건을 고려한 말뚝-지반 접촉면의 동적 전단거동 특성)

  • Kwak, Chang-Won
    • Journal of the Korean Geotechnical Society
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    • v.38 no.5
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    • pp.5-17
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    • 2022
  • A pile is a type of medium for constructing superstructures in weak geotechnical conditions. A pretensioned spun high-strength concrete (PHC) pile is composed of high-strength concrete with a specified strength greater than 80 MPa. Therefore, it has advantages in resistance to axial and bending moments and quality control and management since it is manufactured in a factory. However, the skin friction of a pile, which accounts for a large portion of the pile bearing capacity, is only approximated using empirical equations or standard penetration test (SPT) N-values. Particularly, there are some poor research results on the pile-soil interface under the seismic loads in Korea. Additionally, some studies do not consider geoenvironmental elements, such as groundwater pH values. This study performs sets of cyclic simple shear tests using submerged concrete specimens for 1 month to consider pH values of groundwater and clay specimens composed of kaolinite to generate a pile-soil interface. 0.2 and 0.4 MPa of normal stress conditions are considered in the case of pH values. The disturbed state concept is employed to express the dynamic behavior of the interface, and the disturbed function parameters are newly suggested. Consequently, the largest disturbance increase under basic conditions is observed, and an early approach to the failure under low normal stress conditions is presented. The disturbance function parameters are also suggested to express this disposition quantitatively.