• Korean Journal of Environmental Biology
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• v.27 no.1
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• pp.73-81
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• 2009

Population viability analysis of a Gold-spotted pond frog (Rana chosenica) population at Cheongwon-gun, Chungbuk, in South Korea was conducted and we proposed several suggestions for effective conservation and re-introduction of the species. Simulating a developed model over 1,000 times predicted that the population will exist over 30 years with a relatively low growth rate of 0.113, but with a high probability of extinction as 81.1%. Population growth and extinction probability were the most greatly depended on the rate of successful metamorphosis. In the case of outbreak of amphibian diseases such as Chytridiomycosis and Ranavirus, the population will be easily extinct within 4 years with 100% probability. In a habitat of which carrying capacity is 200, to successfully re-introduce an extinct population, it is initially needed to put 100 individuals of which 83% is males and its age structure is normal-distributed. If we additionally conducts artificial supplementation of 10% individuals every 2 years from 4 years to 10 years after initial reintroduction, the population will become a stable with 0.297 growth rate and 0.290 extinction rate. Our results are the first case of amphibian population viability analysis in Korea and could be used to develop effective conservation and re-introduction plans for endangered Gold-spotted pond frog.

• 대한방사선치료학회:학술대회논문집
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• 2005.06a
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• pp.23-26
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• 2005

Introduction: To evaluate whether modified MUPIT applicator can effectively eradicate recurrent tumor in uterine cervix cancer and reduce rectal complication after complete radiation treatment. Methods and Materials: Modified MUPIT applicator basically consists of an acrylic cylinder with flexible brain applicator , an acrylic template with a predrilled array of holes that serve as guides for interstitial needles and interstitial needles. CT scan was performed to determine tumor volume and the position of interstitial needles. Modified MUPIT applicator was applied to patient in operation room and the accuracy for position of interstitial needles in tumor volume was confirmed by CTscan. Brachytherapy was delivered using modified MUPIT applicator and RALS (192-Ir HDR) after calculated computer planning by orthogonal film. The daily dose was 600cGy and the total dose was delivered 3000cGy in tumor volume by BID. Rectal dose was measured by TLD at 5 points so that evaluated the risk of rectal complication. Result: The application of modified MUPIT applicator improved dramatically dose distributions in tumor volume and follow-up of 3 month for this patient was clinically partial response without normal tissue complication, Rectal dose was measured 34.1cGy, 57.1cGy, 103.8cGy, 162.7cGy, 165.7cGy at each points, especially the rectal dose including previous EBRT and ICR was 34.1cGy, 57.1cGy Conclusion: Patients with locally recurrent tumor in uterine cervix cancer treated with modified MIUPIT applicator can expect reasonable rates of local control. The advantages of the system are the fixed geometry Provided by the template and cylinders, and improved dose distributions in irregular tumor volume without rectal complication

• Journal of Nutrition and Health
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• v.50 no.5
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• pp.447-459
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• 2017

Purpose: Metabolic Syndrome (MetS) is defined as a cluster of inter-connected metabolic disorders involving the glucose metabolism, dyslipidaemia, high blood pressure, and abdominal obesity. The worldwide prevalence has been rapidly increasing to approximately 20~25%, and the prevalence in Korea as of 2012 was reported to be 31.3%. The association of MetS with various diseases needs to be analyzed by conducting an investigation of frequently consumed foods, such as dairy products, fish, and shellfish in prediabetic subjects. Methods: The dietary intake of subjects who met the criteria of the study from January to December 2015 was assessed using the 24-hour recall method. After adjusting the age, sex, BMI, and total energy intake, which are confounding factors that may affect the dietary intake of the subjects, the associations of dairy products, fish, and shellfish intake with the MetS risk factors was analyzed. Results: In prediabetes, the intake of subjects who consumed more than the dairy products median (187.0 g) and the elevation risk of TC [OR, 2.369; 95% CI, 1.057 to 5.312] showed a significant positive association. In prediabetes, the intake of subjects who consumed more than the fish and shellfish median (44.0 g) and the elevation risk of BP showed a significantly weak negative association [OR, 0.073; 95% CI, 0.010 to 0.520]. The probability that the blood LDL cholesterol was ${\geq}100mg/dL$ decreased 0.397 times [95% CI, 0.189 to 0.832]. Conclusion: To control the metabolic risk factors of pre-diabetic and vascular disease subjects, proper dairy, fish and shellfish intake will be important.

• Journal of Life Science
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• v.26 no.2
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• pp.234-240
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• 2016

The Y-maze is widely used to test working memory in behavioral science. For this purpose, spontaneous alternation behavior is monitored, and an increased percentage of spontaneous alternation is regarded as enhanced working memory. However, in some cases, the percentage of spontaneous alternation does not accurately reflect the extent of working memory in rodents. To complement the short-comings of this measure, we developed a new method to evaluate working memory on the Y-maze. This is done by defining all spontaneous alternation cases and P_i, the probability that the rodent achieved spontaneous alternation from each alternation case. After all P_i-values acquired in each animal are summarized, the result is considered as entropy. To validate the new analytical method, mice were raised under either control or an enriched environmental condition for 10 weeks, and working memory behavior on the Y-maze was monitored. The results showed that the new analytical method successfully reproduced significance. In addition, the new method turned out to be more accurate than measurement of the percentage of spontaneous alternation, meaning that, to get higher entropy, alternation should be recorded in all arms and directions. Together, these data indicate that the new analytical method is a useful supplement to the method that compares the percentage of spontaneous alternation, and thus is a good tool with which to evaluate working memory in rodents.

• Current Research on Agriculture and Life Sciences
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• v.31 no.3
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• pp.200-208
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• 2013

The purposes of this study are developing a stress index for each individual major trail in the national parks and contribute to establishing a park management policy based on scientific analyses using the index. We collected data from 144 sections of trails in national parks, conducted the Delphi survey and factor analysis, and generated the stress index by standardizing scores of factors contributing to the stress for each trail. As aresult, total eight factors contributing to the stress were considered and four of them, i.e. the amount of visits, the effect of visits, the degree of trail destruction, and species diversity, were selected to generate the stress index. How to weigh factors was determined by their importance obtained in the second Delphi survey and the average from a 5 point Likert scale. Then, the cumulative probabilities from the standardized scores were graded into five groups. In conclusion, there were twenty trails from the six national parks including Jirisan, Bukhansan, Deogyusan, Naejangsan, Seoraksan in the first grade which gained over 80 as the stress index.

• Journal of the Korea Society for Simulation
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• v.19 no.2
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• pp.73-80
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• 2010

A wireless sensor network which is deployed in hostile environment can be easily compromised by attackers. The selective forwarding attack can jam the packet or drop a sensitive packet such as the movement of the enemy on data flow path through the compromised node. Xiao, Yu and Gao proposed the checkpoint-based multi-hop acknowledgement scheme(CHEMAS). In CHEMAS, each path node enable to be the checkpoint node according to the pre-defined probability and then can detect the area where the selective forwarding attacks is generated through the checkpoint nodes. In this scheme, the number of hops is very important because this parameter may trade off between energy conservation and detection capacity. In this paper, we used the fuzzy rule system to determine adaptive threshold value which is the number of hops for the ACK packets. In every period, the base station determines threshold value while using fuzzy logic. The energy level, the number of compromised node, and the distance to each node from base station are used to determine threshold value in fuzzy logic.

• The Journal of Engineering Geology
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• v.32 no.1
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• pp.27-40
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• 2022

Every year landslides cause serious casualties and property damages around the world. As the accurate prediction of landslides is important to reduce the fatalities and economic losses, various approaches have been developed to predict them. Prediction methods can be divided into landslide susceptibility analysis, landslide hazard analysis and landslide risk analysis according to the type of the conditioning factors, the predicted level of the landslide dangers, and whether the expected consequence cased by landslides were considered. Landslide susceptibility analyses are mainly based on the available landslide data and consequently, they predict the likelihood of landslide occurrence by considering factors that can induce landslides and analyzing the spatial distribution of these factors. Various qualitative and quantitative analysis techniques have been applied to landslide susceptibility analysis. Recently, quantitative susceptibility analyses have predominantly employed the physically based model due to high predictive capacity. This is because the physically based approaches use physical slope model to analyze slope stability regardless of prior landslide occurrence. This approach can also reproduce the physical processes governing landslide occurrence. This review examines physically based landslide susceptibility analysis approaches.

• Proceedings of the KSR Conference
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• 2007.11a
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• pp.480-493
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• 2007

Many railway-advanced countries are using the various types of track to reduce the track maintenance and repair cost according to the improvement of velocity. It spends on much maintenance and repair cost for ballast track due to abrasion of ballast, track irregularity and unisotropical ballast-support stiffness. The ballast track on railway bridge is accelerating the deterioration of ballast according to interaction of railway bridge and track. As continuing the deterioration, it is caused dynamic loads. Due to these effects, it increases negative loads of track and bridge. However, when designing the railway bridge, the effect of ballast track was applicate only dead load, so elastic behavior effect of ballast track is not influenced. Therefore, this paper presumes the stiffness of ballast track on railway bridge considering dynamic behavior of railway bridge, it was evaluated that effect on dynamic behaviors of railway bridge according to ballast track stiffness.

• The Korean Journal of Nuclear Medicine
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• v.30 no.3
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• pp.332-337
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• 1996

Purpose : It has been known that the activity of extracellular matrix degradative enzymes such as collagenase correlate well with the metastatic potential of various tumor cells in experimental study. This study was aimed at comparing the activities of type IV collagenase with bone scan findings in patients with breast cancer. Materials and Methods : We retrospectively correlated bone scan findings with the results of immunohistochemical staining for 92kDa, 72kDa type IV collagenase in 28, and 30 patients with metastatic breast cancer, respectively, as well as 23, and 27 patients with primary breast cancer, respectively. The immunohistochemical staining was performed with tissue specimens obtained from primary or metastatic breast tumor lesions. The amounts of the enzyme were graded from 0 to 4 and scored by multiplication with the percentage of tumor cells. The confidence of bone scan interpretation for metastasis was also scored from 1 to 5 with increasing probability. Results : There was a significant difference in enzyme scores between patients with and without metastasis. In patients with primary breast cancer group, the frequency of patients with enzyme score of less than 170 were 96%(26/27) and 100%(26/26) with 92kDa and 72kDa collagenase, respectively. In contrast, in patients with metastatic breast cancer group, the frequency of patients with enzyme score of more than 200 were 93%(28/30) and 87%(26/30) with 92kDa and 72kDa collagenase, respectively. All patients with each enzyme score of less than 170 show no active bony metastasis, however, there were variable bone scan findings in patients with each enzyme score of more than 200. Conclusion : Bone scan is useful to confirm, localize or follow up of bony metastasis in patients with each enzyme scores of more than 200. Acitve metastatic lesions were hardly seen on the bone scintigraphy in patients with collagenase scores of less than 170.

• Childhood Kidney Diseases
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• v.2 no.2
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• pp.145-151
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• 1998

Purpose : DMSA renal scan is known as a valuable method for evaluating acute pyelonephritis and renal scar in patients with febrile urinary tract infection or vesicoureteral reflux. We made this study, to determine the most effective use of DMSA renal scan. Methods : 155 children were admitted to the Pediatric Department of Yonsei University, Severance hospital with the symptom of urinary tract infection from January, 1992 to June, 1995. DMSA scan, renal ultrasound and VCUG were performed. One consisted of 29 patients with the diagnosis of acute pyelonephritis without vesicoureteral reflux and the otherconsistedofllpatientswithvesicoureteralreflux. Results : The follow-up DMSA scans at mean $0.99{\pm}0.46$ months after the initial DMSA scans were performed in the 29 children with acute pyetonephritis. 21($72.4\%$) of 29 children showed normal DMSA scans. 8 children with abnormal DMSA scans had follow-up DMSA scans at 2.5 months after the initial scans and 6 of 8 children showed normal DMSA scans. Only 12($41.4\%$) of 29 children showed abnormal renal ultrasound. The data about DMSA scans in 32 children with vesicoureteral reflux showed that there were abnormal DMSA scans in Grade $I;25.0\%$, Grade $II;44.5\%$, Grade $III;64.3\%$, Grade $IV;92.9\%$ and Grade $V;100.0\%$. There was a significant difference in that 36 renal unit ($68.0\%$) on DMSA renal scan and 26 renal units ($49.1\%$) on renal ultrasound showed abnormal finding(P<0.05). Conclusion : DMSA renal scan is more useful than renal ultrasound for the diagnosis of acute pyelonephritis. It is considered that if the initial DMSA scan is abnormal, a follow-up DMSA scan must be performed after 10weeks (8-12weeks) and the change in DMSA scan evaluated.