• The korean journal of orthodontics
• /
• v.16 no.1
• /
• pp.7-34
• /
• 1986

본 연구목적은 여자성인교정을 위한 치료목표를 수립하기 위한 기준을 설정하는데 있다. 이용된 연구자료는 96명의 한국인 TV탈랜트와 영화배우 또는 패션모델중 교합과 안모를 평가하여 선정된 30명의 측모두부X선규격사진이었으며 선정된 표본의 평균연령은 20.16세였다. 연구방법은 측모경조직분석을 위해 Downs분석, Northwestern분석, Steiner분석, Wylie분석, Tweed분석, Dimensional linear분석법이 이용되었고 측모연조직분석을 위해 Holdaway연조직분석법이 적용되었다. 조사된 계측치들은 Apple II 48K system을 이용하여 각항목에 대한 평균치와 표준편차를 산출하였으며 백인, 한국인, 일본인의 기존계측치와 비교하였다. 그 연구결과는 다음과 같다. I. 경조직분석 (1) 본 연구와 백인과의 비교 본 연구에서는 백인에 비해 하악이 후퇴되었고 상${\cdot}$하악절치는 순측경사를 보였다. 또한 하악하연경사가 심했다. (2) 본 연구와 한국인정상성인여자(이 연구)의 계측치 비교 이의 연구계측치에 비해서 상악이 후퇴되어있고 상${\cdot}$하악절치는 설측경사를 보였다. 따라서 본 연구의 안모형태는 이의 한국인정상성인여자에 비해서 직선형안모를 보였다. (3) 본 연구와 일본정상인의 계측치 비교 일본정상인에 비해 하악이 돌출되었고 상${\cdot}$하절치는 설측경사를 보였다. 또한 안모의 상부고경과 하악크기는 일본정상인에 비해 크게 나타났다. II. 연조직분석 연조직분석의 11항목중 H-선에 대한 연조직 subnasal과 하순의 계측치가 Holdaway의 acceptable range를 벗어났다. 그 이유는 본연구에서 하악이 상대적으로 후퇴양상을 보였기 때문이라고 사료된다. 이외항목의 계측치들이 acceptable range내에 있다는 것은 연조직이 경조직의 이동에 따라 움직이고 있음을 의미한다. III. Downs분석, Northwestern분석, Steiner분석, Wylie분석, Tweed분석, Dimensional linear measurements분석을 위한 평균치, 표준편차, Polygon도표를 작성함으로써 한국성인여자교정의 진단과 치료목표를 정하는데 지침이 된다고 사료된다.

• Proceedings of the KSLP Conference
• /
• 1996.11a
• /
• pp.79-79
• /
• 1996

최근 들어 음성에 대한 일반인들의 관심이 높아지면서 음성이상을 호소하며 이비인후과 외래를 방문하는 환자가 점차적으로 증가하는 추세에 있다. 그러나 이러한 음성이상을 객관적으로 평가할 수 있는 기준이 국내에는 거의 없는 실정이다. 이에 저자들은 본 연구에서 기왕력 상 폐질환이나 신경계질환, 후두질환을 앓은 적이 없으며 음성조율 기관에 이상이 없고 정상적인 청력을 가진 10세에서 69세까지의 무작위 추출된 정상 한국인 남자 112명과 여자 122명을 대상으로 Aerophone II voice function analyzer를 이용하여 공기역동학적 검사 중 최대발성지속시간(maximum phonation time), 평균호기류율(mean airflow rate), 발성율(phonation quotient), 발성시 기류량(phonatory flow volume) 및 성문하압(subglottal pressure)의 정상 한국인의 남녀 년령별 평균치를 측정하고자 하였다. (중략)

• Proceedings of the Korean Society of Applied Pharmacology
• /
• 1993.04a
• /
• pp.168-168
• /
• 1993

신의약품의 생식독성 평가를 위해서는 타독성시험의 경우와 마찬가지로 NOEL (no observed effect level) 의 범위를 확립하는 일이 매우 중요한데, 이것은 정상치(control values), 자연발생소견 (spontaneous findings)등과 비교함으로서 가능하다. SPF 동물을 이용한 독성실험은 선진국에 비해 역사가 짧을 뿐만 아니라 아직 풍부한 기초자료가 확립되지 않아 외국의 자료들을 인용하고 있는 실정이다. 본 연구에서는 랫트를 이용한 최기형 시험결과의 효율적인 평가를 위해 생식독성 검사항목의 기초 데이타를 확립하였다. 이를 위해 화학연구소 실험동물육종실에서 입수한 SPF: Sprague- Dawley 랫트를 이용해 1989년부터 1991년까지 실시한 생식독성 시험의 대조준 데이타 (체중, 사료소비량, 장기중량, 제왕절개성적, 외표, 내부장기 및 골격검사성적, 자연분만군 시험성적 등)를 분석하였다. 요늑의 발현율, 견인력 시험결과 및 피모발생 일평이 외국의 타 연구기판 데이타와 다소 차이를 나타냈을 뿐 기타 항목들은 거의 일치하는 정상치를 보였다. 아울러 기형, 변이, 골화지연 등으로 구분되는 골격소견의 합리적인 평가를 위해 랫트 골격소견 평가기준을 정했고 최기형 시험에서 얻어지는 데이터의 통계처리 방법을 보완, 체계화하였다. 본 연구결과는 Sprague-Dawley 계통 랫트외 생물학적 정외는 물론 효율적인 생식독성 평가를 위한 소중한 기초 자료가 될 것으로 사료된다.

• The Korean Journal of Zoology
• /
• v.29 no.2
• /
• pp.107-120
• /
• 1986

The activities of serum of serum lactate dehydrogenase (SLDH), serum alkaline phosphatase (SALP), serum creatine phosphokinase (SCPK), and their isozymes were determined in adult male Sprague-Dawley rats acclimated to cold environment $(4\\pm1^\\circC)$ for 36 days. The SLDH activity was significantly higher in the early stage of acclimated period. The steady state of SLDH activity seemed to be reached by the end of acclimated period. Electrophoretic separation of serum of control rat showed three SLDH isozymes. Isozymes SLDH4 and SLDH5 appeared most prominently, whereas only trace of SLDH1 or SLDH2 was found. The increase in SLDH level during acclimation to cold environment is a reflection of an immediate increase in the SLDH1, SLDH2, and SLDH3 type of SLDH isozyme. The acclimation to cold environment increased significantly level of SALP in the early state of acclimated period. SALP activity showed a attaining steady state with the resting level after transient rise. Electrophoretic separation of SALP of control rats showed the SALP1 and SALP2 fractions. The transient rise in SALP activity of rats acclimated to cold environment coincided with a transient rise in SALP1 fraction. Immediately after exposure to cold environment, there was significant elevation in SCPK activity. Value returned to normal after transient rise. A new steady state of SCPK activity seemed to be reached by 36 days. It may be inferred from the above data that thermal compensation appears to result from a change in the activity of an enzyme and that the SLDH, SLDH-isozyme, SALP-isozyme, and SCPK may be involved directly or indirectly in thermoregulation during acclimation to cold environment.

• Journal of the korean academy of Pediatric Dentistry
• /
• v.38 no.1
• /
• pp.75-81
• /
• 2011

Supernumerary teeth are in excess of the normal number of teeth in either the primary or permanent dentitions. They are classified into supplemental teeth resembling those of the normal series and rudimentary teeth with abnormal shapes, according to their form. Most of the supernumerary teeth are rudimentary form, and supplemental teeth are much less common. Sulppemental teeth are most common in the permanent maxillary lateral incisor area and clinicians should be careful with differential diagnosis from normal teeth. Unerupted supernumerary teeth may produce several complications such as delayed eruption, displacement of permanent teeth, diastema, root resorption and cyst formation. Early detection and proper treatment plan according to the tooth alignment and root formation stage are important. Here we report 3 cases of unilateral or bilateral normal incisor shaped supernumerary lateral incisors treated by eruption observation, surgical extraction and orthodontic treatment with resin build-up.

• Tuberculosis and Respiratory Diseases
• /
• v.50 no.3
• /
• pp.320-333
• /
• 2001

Background : Peak expiratory flow (PEF) provides a simple, quantitative, and reproducible measure of the existence and severity of airflow obstructions. Peak flow meters are designed to monitor the condition asthma patients. There are many reports showing the normal predicted value of PEF in other countries. Studies on healthy Korean adults have been performed in a relatively small sample number and a lower limit for the normal value was not reported. Therefore, an attempt to provide normal predictive PEF value with a lower limit was made. Method : The PEF(Mini-Wright Peak Flow Meter) measurements and spirometry were done in 233 men and 631 women without history of respiratory disease. All subjects were non-smokers with no respiratory symptoms. The normal predictive value and its lower limit were developed by multiple regression analysis. The result was compared with regression equations in other reports. Results : The regression equation for the normal PEF predictive value(L/min) is $25.117+4.587{\times}$Age(year)-$0.064{\times}Age^2+2.931{\times}$Height(cm) in men($R^2=025$), and 146.942-$0.011{\times}Age^2+1.795{\times}$Height(cm)+$0.836{\times}$Weight(kg) in women($R^2=0.21$). The regression equation for the lower limit of this value (L/min) is $25.117+4.587{\times}$Age(year)-$0.064{\times}Age^2+1.936{\times}$Height(cm) in men, and $146.942-0.011{\times}Age^2+1.232{\times}$Height(cm)+$0.481{\times}$Weight(kg) in women. The residuals were normally distributed. The PEF in Korean males was sililar to those reported in British and Japanese subjects. The PEF in Korean females was similar to that in British subjects, but higher than the PEF in Japanese subjects. The lower limit of normal value was 71% of normal predictive PEF value in men and 76% in women. Conclusion : The normal predictive PEF value and its lower limit was measured from 233 male and 631 female asymptomatic, lifelong non-smoking participants. The normal predictive value was different from those of other studies on Korean subjects. Therefore, further studies are required.

• 치위협보
• /
• s.96
• /
• pp.1-12
• /
• 2005

• Journal of the korean academy of Pediatric Dentistry
• /
• v.37 no.1
• /
• pp.136-142
• /
• 2010

Ectopic eruption is defined as the eruption of the tooth in an abnormal position or orientation. In the molar region, ectopic eruption may cause distal root resorption and premature exfoliation of the neighbor teeth and uncontrolled space loss is followed. Prolonged partial impaction of the permanent molar may also cause undetected caries or abscess formation of the neighbor teeth. While 66% of ectopically erupting permanent molars are corrected spontaneously without treatment, the treatment is necessary for the irreversible ectopic eruption cases. The optimal treatment approach depends on a number of factors including the clinical eruption status of the molar, amount of enamel ledge and the mobility of the neighbor tooth, and the presence of pain or infection. This case report presents the results of treatment of the ectopically erupting maxillary first permanent molars and mandibular second molars using elastic separators or modified Halterman appliance with or without surgical approach.

• The korean journal of orthodontics
• /
• v.39 no.2
• /
• pp.112-119
• /
• 2009

Objective: To develop a mixed dentition analysis method in consideration of the normal variation of tooth sizes. Methods: According to the tooth-size of the maxillary central incisor, maxillary 1st molar, mandibular central incisor, mandibular lateral incisor, and mandibular 1st molar, 307 normal occlusion subjects were clustered into the smaller and larger tooth-size groups. Multiple regression analyses were then performed to predict the sizes of the canine and premolars for the 2 groups and both genders separately. For a cross validation dataset, 504 malocclusion patients were assigned into the 2 groups. Then multiple regression equations were applied. Results: Our results show that the maximum errors of the predicted space for the canine, 1st and 2nd premolars were 0.71 and 0.82 mm residual standard deviation for the normal occlusion and malocclusion groups, respectively. For malocclusion patients, the prediction errors did not imply a statistically significant difference depending on the types of malocclusion nor the types of tooth-size groups. The frequency of prediction error more than 1 mm and 2 mm were 17.3% and 1.8%, respectively. The overall prediction accuracy was dramatically improved in this study compared to that of previous studies. Conclusions: The computer aided calculation method used in this study appeared to be more efficient.

• Korean Journal of Plant Resources
• /
• v.19 no.5
• /
• pp.602-605
• /
• 2006

Effects of Codium fragile ext. on lipid lowering and antioxidant activities were investigated in hyperlipidemic rat. Concentration of FFA and triglyceride in plasma showed a tendency to decrease in Codium fragile ext. groups. Concentration of plasma total cholesterol and LDL-cholesterol in Codium fragile ext. groupsshowed a low values than those of control group. However concentration of HDL-cholesterol showed no significant difference in all treatment groups. Concentration of liver total cholesterol and triglyceride showed a tendence to decrease in Codium fragile ext. groups. Concentration of plasma and liver TBARS showed a low values in Codium fragile ext. groups. The values of GSH-Px activity showed a tendency to increase in the Codium fragile ext. groups, However the values of SOD and CAT activity showed no significant difference in all treatment groups.