• Journal of Chest Surgery
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• v.37 no.8
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• pp.672-683
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• 2004

Background: The treatment results of the advanced lung carcinoma is not satisfactory with the present therapeutic modalities: surgical resection, anti-cancer chemotherapy, and radiotherapy or combination therapy. To predict the prognosis of the non-small-cell lung carcinoma, TNM classification has been was as the basic categorization; however, it has been not satisfactory. It is necessary to consider the causes and the prognosis of the lung carcinoma from another points of view rather the conventional methods. We intended to find out the relationship between the major apoptotic factor, p53 gene and the prognosis of the patient with lung carcinoma. Material and Method: Three hundreds and fifty-nine patients with lung carcinoma who underwent surgery were analysed. We observed p53 protein accumulated in the cellular nuclei. The p53 protein was detected by immuno-histo-chemical method. We collected information of the patient retrospectively. Result: p53 protein densities were observed in 40% in average as a whole. The protein density was 44 percent in man, 25 percent in woman, 49 percent in the squamous cell carcinoma, and 38 percent in the adenocarcinoma. There were significant correlations between the p53 protein density and the mortality in the squamous cell carcinoma (p=0.025), follow-up duration in TNM stage I group (p=0.010), and follow-up duration in the lobectomy patient group (p=0.043), and tumor cell differentiation (p=0.009). p53 protein densities were significantly different between the lobectomy and the pneumonectomy group (p=0.044). Conclusion: The authors found that p53 protein had some correlations with the prognosis of the lung cancer partially in some factors. We suggest the p53 protein density could be used as a marker of prognosis in the non-small-cell lung carcinoma.

• The Korean Journal of Nuclear Medicine Technology
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• v.12 no.1
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• pp.91-98
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• 2008

Purpose: Radio-isotopes (RI) use has been steadily developing due to industrial and technical development in the modern medical society. Particularly, popularization of domestic cyclotrons dramatically enable hospitals to produce and use diagnostic radio-isotopes. Generally, only specific facilities such as hospitals, research institutes, nuclear power plants and universities can use radio-isotopes, they are also responsible for ventilation system. The strength of radioactivity in the air is strongly regulated and controlled by korea atomic energy law in Korea Institue of Nuclear Safety (KINS), so that air radioactivity exposure can lead to environmental pollution surrounding places. In this study, we'd like to find out the investigation and the present condition of the controlled ventilation system in domestic hospitals by an emission standard from KINS, and try to reach an agreement about how to use the ventilation system. Result: Definition of filters, features and structures of pre-filters, hepa-filters, charcol filters, filter exchange procedures and precautions are explained. RI deflation concentration and filter exchange cycle have been presented as a standard prescribed in the rules of KINS. The Radiation Control Management System (RCMS) introduced by Seoul National University Bundang Hospital linking to digital pressure gauge with computer controller in another medical facilities were described in details. Conclusions: The system of medical facilities using RI has been remarkably developing in 21 century. Especially, radiation safety control system has also been grown rapidly into the subdivision, specialization, advanced technology along with international technical improvement. However, As far as current RI ventilation system is concerned, it has nothing better than doing in the past. Preferentially, to reinforce this, more sophisticated system with strict periodic filter exchange and exhaust air control guidance should be introduced by applying brilliant domestic information technology for RCMS and digital gauge method. From personal point of view as a radiation safety manager, I have provide with present problems and improvements. Futhermore, more improved guidance should be conducted.

• Korean Journal of Ecology and Environment
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• v.48 no.4
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• pp.229-237
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• 2015

This study aims to offer basic data to effectively preserve and manage pine forests using more precise pine forests' distribution status. In this regard, this study predicts the geographical distribution change of pine forests growing in South Korea, due to climate change, and evaluates the spatial distribution characteristics of pine forests by age. To this end, this study predicts the potential distribution change of pine forests by applying the MaxEnt model useful for species distribution change to the present and future climate change scenarios, and analyzes the effects of bioclimatic variables on the distribution area and change by age. Concerning the potential distribution regions of pine forests, the pine forests, aged 10 to 30 years in South Korea, relatively decreased more. As the area of the region suitable for pine forest by age was bigger, the decreased regions tend to become bigger, and the expanded regions tend to become smaller. Such phenomena is conjectured to be derived from changing of the interaction of pine forests by age from mutual promotional relations to competitive relations in the similar climate environment, while the regions suitable for pine forests' growth are mostly overlap regions. This study has found that precipitation affects more on the distribution of pine forests, compared to temperature change, and that pine trees' geographical distribution change is more affected by climate's extremities including precipitation of driest season and temperature of the coldest season than average climate characteristics. Especially, the effects of precipitation during the driest season on the distribution change of pine forests are irrelevant of pine forest's age class. Such results are expected to result in a reduction of the pine forest as the regions with the increase of moisture deficiency, where climate environment influencing growth and physiological responses related with drought is shaped, gradually increase according to future temperature rise. The findings in this study can be applied as a useful method for the prediction of geographical change according to climate change by using various biological resources information already accumulated. In addition, those findings are expected to be utilized as basic data for the establishment of climate change adaptation policies related to forest vegetation preservation in the natural ecosystem field.

• Korean Journal of Remote Sensing
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• v.31 no.5
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• pp.441-448
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• 2015

Lack of agricultural information for food supply and demand in Democratic People's republic Korea(DPRK) make people sometimes confused for right and timely decision for policy support. We carried out a study to estimate paddy rice yield in DPRK using MODIS NDVI reflecting rice growth and climate data. Mean of MODIS $NDVI_{max}$ in paddy rice over the country acquired and processed from 2002 to 2014 and accumulated rainfall collected from 27 weather stations in September from 2002 to 2014 were used to estimated paddy rice yield in DPRK. Coefficient of determination of the multiple regression model was 0.44 and Root Mean Square Error(RMSE) was 0.27 ton/ha. Two-way analysis of variance resulted in 3.0983 of F ratio and 0.1008 of p value. Estimated milled rice yield showed the lowest value as 2.71 ton/ha in 2007, which was consistent with RDA rice yield statistics and the highest value as 3.54 ton/ha in 2006, which was not consistent with the statistics. Scatter plot of estimated rice yield and the rice yield statistics implied that estimated rice yield was higher when the rice yield statistics was less than 3.3 ton/ha and lower when the rice yield statistics was greater than 3.3 ton/ha. Limitation of rice yield model was due to lower quality of climate and statistics data, possible cloud contamination of time-series NDVI data, and crop mask for rice paddy, and coarse spatial resolution of MODIS satellite data. Selection of representative areas for paddy rice consisting of homogeneous pixels and utilization of satellite-based weather information can improve the input parameters for rice yield model in DPRK in the future.

• Neonatal Medicine
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• v.17 no.1
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• pp.94-101
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• 2010

Purpose:In recent years, Korea has showed a steady increase in the frequency of teenage birth, while the overall birth rate has declined. As the teenage birth is known as a high risk pregnancy itself, we examined perinatal complications of teenage mothers and whose neonates in aspects of medical problem, and social status and support. Methods:We examined the perinatal characteristics of teenage mothers and whose babies, who were hospitalized at Korea University Ansan Hospital from January 2004 to July 2009 using medical records retrospectively. Twenty-seven teenage mothers and their 28 babies were enrolled in this study. Results:Teenage mothers were all unmarried and showed high rates of preterm labor, maternal anemia, and unexpected delivery. Among them, 11 (40.7%) were from families that were separated. Eleven mothers (40.7%) did not have any antenatal care. There were high rates of prematurity and low birth weight (60.7% and 64.3%, respectively). The complication included: respiratory distress syndrome, patent ductus arteriosus and necrotizing enterocolitis. Fourteen babies (51.9%) were not going to be brought up by their biological parents. Conclusion:Teenage pregnancy had high rates of preterm labor and associated complications, often caused by the lack of proper antenatal care. Babies from unmarried mothers were likely to be adopted and this could be a social burden. Therefore, to reduce unplanned teenage pregnancy and births, sex education and social supports should be provided to all teenagers.

• Korean Journal of Agricultural and Forest Meteorology
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• v.7 no.2
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• pp.132-140
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• 2005

This study was conducted to develop regional site index equations for main tree species in Gangwon, Gyunggi-Chungcheong, Gyungsang, and Jeolla area of Korea, using environmental and soil factors obtained from a digital forest site map. Using the large data set obtained from the digital forest map, a total of 28 environmental and soil factors were regressed on site index by tree species for developing the best site index equations for each of the regions. The selected main tree species were Larix 1eptolepis, Pinus koraiensis, Pinus densiflora, Pinus thunbergii, and Quercus acutissima. Finally, four to five environmental and soil factors by species were chosen as independent variables in defining the best regional site index equations with the highest coefficients of determination $(R^2)$. For those site index equations, three evaluation statistics such as mean difference, standard deviation of difference and standard error of difference were applied to the data sets independently collected from fields within the region. According to the evaluation statistics, it was found that the regional site index equations by species developed in this study conformed well to the independent data set, having relatively low bias and variation. It was concluded that the regional site index equations by species had sufficient capability for the estimation of site productivity.

• Korean Journal of Agricultural and Forest Meteorology
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• v.3 no.4
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• pp.199-205
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• 2001

This study was conducted to figure out temperature profiles of a partially developed paddy rice canopy, which are necessary to run plant disease forecasting models. Air temperature over and within the developing rice canopy was monitored from one month after transplanting (June 29) to just before heading (August 24) in 1999 and 2001. During the study period, the temporal march of the within-canopy profile was analyzed and an empirical formula was developed for simulating the profile. A partially developed rice canopy temperature seemed to be controlled mainly by the ambient temperature above the canopy and the water temperature beneath the canopy, and to some extent by the solar altitude, resulting in alternating isothermal and inversion structures. On sunny days, air temperature at the height of maximum leafages was increased at the same rate as the ambient temperature above the canopy after sunrise. Below the height, the temperature increase was delayed until the solar noon. Air temperature near the water surface varied much less than those of the outer- and the upper-canopy, which kept increasing by the time of daily maximum temperature observed at the nearby synoptic station. After sunset, cooling rate is much less at the lower canopy, resulting in an isothermal profile at around the midnight. A fairly consistent drop in temperature at rice paddies compared with the nearby synoptic weather stations across geographic areas and time of day was found. According to this result, a cooling by 0.6 to 1.2$^{\circ}C$ is expected over paddy rice fields compared with the officially reported temperature during the summer months. An empirical equation for simulating the temperature profile was formulated from the field observations. Given the temperature estimates at 150 cm above the canopy and the maximum deviation at the lowest layer, air temperature at any height within the canopy can be predicted by this equation. As an application, temperature surfaces at several heights within rice fields were produced over the southwestern plains in Korea at a 1 km by 1km grid spacing, where rice paddies were identified by a satellite image analysis. The outer canopy temperature was prepared by a lapse rate corrected spatial interpolation of the synoptic temperature observations combined with the hourly cooling rate over the rice paddies.

• Korean Journal of Agricultural and Forest Meteorology
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• v.12 no.1
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• pp.1-10
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• 2010

A regional climate model (RCM) can be a powerful tool to enhance spatial resolution of climate and weather information (IPCC, 2001). In this study we conducted dynamical downscaling using Weather Research and Forecasting Model (WRF) as a RCM in order to obtain high resolution regional agroclimate indices over the Korean Peninsula. For the purpose of obtaining detailed high resolution agroclimate indices, we first reproduced regional weather for the period of March to June, 2002-2008 with dynamic downscaling method under given lateral boundary conditions from NCEP/NCAR (National Centers for Environmental Prediction/National Center for Atmospheric Research) reanalysis data. Normally, numerical model results have shown biases against observational results due to the uncertainties in the modelis initial conditions, physical parameterizations and our physical understanding on nature. Hence in this study, by employing a statistical method, the systematic bias in the modelis results was estimated and corrected for better reproduction of climate on high resolution. As a result of the correction, the systematic bias of the model was properly corrected and the overall spatial patterns in the simulation were well reproduced, resulting in more fine-resolution climatic structures. Based on these results, the fine-resolution agro-climate indices were estimated and presented. Compared with the indices derived from observation, the simulated indices reproduced the major and detailed spatial distributions. Our research shows a possibility to simulate regional climate on high resolution and agro-climate indices by using a proper downscaling method with a dynamical weather forecast model and a statistical correction method to minimize the model bias.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.56 no.3
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• pp.233-243
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• 2011

This experiment was conducted to investigate the effect of future climate change on growing period and temperature in different rice maturity types as global warming progressed, where Odaebyeo, Hwaseongbyeo, Ilpumbyeo were used as a representative cultivar of early, medium, and medium-late rice maturity type, respectively, and A1B scenario was applied to weather data for future climate change at 57 sites in Korea. When cropping season was not adjusted to climate change, entire growing period and growing temperature were shorten and risen, respectively, as global warming progressed. On the other side, when cropping season was adjusted to climate change, growing period and temperature after heading date were not changed in contrast to growing period and growing temperature before heading which were more seriously shortened and risen as global warming progressed than in not adjusted cropping season. It is supposed that adjusting cropping season to climate change can alleviate rice yield reduction and quality deterioration to some degree by improving growing temperature condition during grain-filling period, but also still have a limit such as seriously shortened growing period indicating that there need to develope actively new rice cultivation methods and varieties for future climate change.

• Applied Microscopy
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• v.39 no.1
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• pp.57-64
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• 2009

The trapping leaves of Drosera capture insects by secreting sticky mucilage from numerous glandular trichomes (GTs) that are developed on the leaf epidermis. The present study examines and compares the structural features of those trichomes in Drosera binata and D. pygmy with the use of light and electron microscopy. The study focuses primarily on the development and differentiation pattern of the GTs during growth. Upon examination, the upper and lower epidermis were readily distinguishable by the features of GTs in developing leaves. In particular, the GTs were dense in the upper epidermis and along the leaf margin. In D. binata, the capitate GTs with elongated stalk and sessile peltate GTs were found most commonly, whereas only capitate GTs with varying degrees of the stalk length were observed in D. pygmy. Up to ca. $2.2{\sim}3.4\;mm$ long capitate GTs were seen in the leaf margins of D. binata and ca. $3.7{\sim}4.2\;mm$ long GTs having racket-like head with adaxial hemispheric structures, otherwise known as tentacles, were noted in the leaf margin of D. pygmy. The peltate GTs were found to be distributed in the lower epidermis of D. binata. In both species, head cells were dense with cytoplasm containing high numbers of Golgi bodies, ER, mitochondria and small vesicles. Secretory materials accumulated within numerous small vacuoles, then fused together to form a single large vacuole, which serves as a secretory cavity. Flection movement of the marginal GTs and leaf blade GTs, and increased mucilage secretion from the head cells upon contact with prey during the capturing process are considered to be major factors in their active insectivorous mechanism. The findings of this study will be useful in comparisons to similar findings in other species that form adhesive trapping leaves, such as Drosophyllum or Pinguicula., further contributing a better understanding of the function and structure of the trapping leaves of carnivorous plants.