• Title/Summary/Keyword: 전자선치료

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The Calculation of Energy Distributions for Clinical Electron Beams from Mono Energetic Depth dose Data (단일에너지 깊이선량률 자료에 의한 치료용 전자선의 에너지분포 계산)

  • 이정옥;정동혁
    • Progress in Medical Physics
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    • v.15 no.1
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    • pp.39-44
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    • 2004

  • The energy distributions for clinically used electron beams from measured and calculated mono energetic depth dose values were calculated. The energy distributions having the minimum difference between the measured and reduced values of depth dose are determined by iterations based on least square method. The nominal energies of 6, 9, 12, 15 MeV clinical electron beams were examined. The Monte Carlo depth dose calculations with determined energy distributions were peformed to evaluate those distributions. In a comparison of the calculated and measured depth dose data, the standard errors are estimated within $\pm$ 3% from surface to R$_{80}$ depth and within $\pm$4% from the surface to near the range for all electron beams. This can be practically applied to determine the energy distributions for clinically used electron beams.

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Cell Death of Human Promyelocytic Leukemia Cell after Low Dose of Electron Beam Irradiation with TNF-α (저 농도의 전자선을 조사한 전골수구성 백혈병 세포 죽음에서의 TNF-α 작용 효과)

  • Kim, Dong Hyun;Ko, Seong-Jin
    • The Journal of the Korea Contents Association
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    • v.14 no.6
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    • pp.241-246
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    • 2014

  • Acute promyelocytic leukemia (APL) is a cancer of the blood. Although electron beam (EB) irradiation is used with other anti-cancer agents, EB irradiation can be harmful to normal tissues around the cancer. In the present study, we evaluate the differential cytotoxic effect of EB irradiation with other molecules, including TNF-${\alpha}$, on DMSO-treated HL-60 cells and HL-60 cells. HL-60 cells are the human promyleocytic leukemia cell line and are differentiated by DMSO. DMSO-treated HL-60 cells are considered to be normal granulocytic cells. In these results, TNF-${\alpha}$ may be used as the potential agent for the treatment of blood cancer without side effects in low dose of EB irradiation therapy.

  • https://doi.org/10.5392/JKCA.2014.14.06.241 인용 PDF KSCI

Evaluating Surface dose of Treatment Immobilization Devices according to their Electron Energy (전자선에너지에 따른 치료보조기구의 표면선량 평가)

  • Park, Chul-Woo;Im, In-Chul
    • The Journal of the Korea Contents Association
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    • v.10 no.6
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    • pp.360-363
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    • 2010

  • This study evaluated surface dose of treatment immobilization devices such as Themo-plastic, Vac-lock, Cotton and Plaster according to their electron energy. Using a linear accelerater, a plane parallel chamber was set up on 6Mev, 9Mev, 12Mev and 15Mev. A distance between a source and a surface was 100cm and a field size was 10cm*10cm. An incident angle was 0 degree and a radiation dose was 100MU. To decrease an error, the measurement repeated 3 times. The analysis reveals that the surface dose of Vac-lock was the highest and Themo-plastic, Plaster and Cotton were high in order.

  • https://doi.org/10.5392/JKCA.2010.10.6.360 인용 PDF KSCI

Dose distribution at junctional area abutting X-ray and electron fields (X-선과 전자선의 인접조사에서 접합 조사면에서의 선량분포)

  • Yang, Kwang-Mo
    • The Journal of Korean Society for Radiation Therapy
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    • v.16 no.1
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    • pp.91-99
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    • 2004

  • Purpose : For the head and neck radiotherapy, abutting photon field with electron field is frequently used for the irradiation of posterior neck when tolerable dose on spinal cord has been reached. Materials and methods : Using 6 MV X-ray and 9 MeV electron beams of Clinac1800(Varian, USA) linear accelerator, we performed film dosimetry by the X-OMAT V film of Kodak in solid water phantom according to depths(0 cm, 1.5 cm, 3 cm, 5 cm). 6 MV X-ray and 9 MeV electron(1Gy) were exposes to 8cm depth and surface(SSD 100cm) of phantom. The dose distribution to the junction line between photon($10cm{\times}10cm$ field with block) and electron($15cm{\times}15cm$ field with block) fields was also measured according to depths(0 cm, 0.5 1.5 cm, 3 cm, 5 cm). Results : At the junction line between photon and electron fields, the hot spot was developed on the side of the photon field and a cold spot was developed on that of the electron field. The hot spot in the photon side was developed at depth 1.5 cm with 7 mm width. The maximum dose of hot spot was increased to $6\%$ of reference doses in the photon field. The cold spot in the electron side was developed at all measured depths(0.5 cm-3 cm) with 1-12.5 mm widths. The decreased dose in the cold spot was $4.5-30\%$ of reference dose in the electron field. Conclusion : When we make use of abutting photon field with electron field for the treatment of head and neck cancer we should consider the hot and cold dose area in the junction of photon and electron field according to location of tumor.

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