• Title/Summary/Keyword: 전도 내성

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Implementation of Classic McEliece Public Key Generation Quantum Circuit (Classic McEliece 공개키 생성 양자회로 구현)

  • Yu-jin Oh;Kyung-bae Jang;Se-jin Lim;Hwa-jeong Seo
    • Proceedings of the Korea Information Processing Society Conference
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    • 2023.11a
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    • pp.179-182
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    • 2023
  • 양자 알고리즘인 Shor 알고리즘으로 공개키 암호의 보안성이 붕괴됨에 따라 NIST는 양자내성암호 표준화 공모전을 진행하였다. 또한 암호시스템의 양자 후 보안을 위해, 양자 컴퓨터상에서 암호 알고리즘들을 미리 구현하고 분석하는 연구가 진행되고 있다. 이에 본 논문에서는, NIST 양자내성암호 공모전 Round 4의 후보 알고리즘인 Classic McEliece의 공개키 생성 양자 회로 구현을 제시하고 회로에 필요한 양자 자원을 추정한다.

Drug Resistance and R Plasmid of Enterococcus Isolated from Patients (환자(患者)에서 분리(分離)한 Enterococcus의 약제내성(藥劑耐性)과 R Plasmid)

  • Lee, Hern-Ku;Ha, Tai-You
    • The Journal of the Korean Society for Microbiology
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    • v.13 no.1
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    • pp.7-16
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    • 1978
  • One hundred and three clinical isolates of enterococci were examined for susceptibility to 8 antibiotics, and transferability and transfer frequency of R plasmid. Ampicillin was the most active, followed in decreasing order by rifampin, amikacin and chloramphenicol, and tetracycline. High-level resistance(${\geq}2,000{\mu}g/ml$) to kanamycin, streptomycin, and gentamicin, known as the most active of the aminoglycosides to enterococcus, was present in 26.2%, 21.4%, and 18.3% of the isolates, respectively. In the drug susceptibility of the species, S. zymogenes was the most resistant and S. durans was the most sensitive to tested antibiotics. We could observed the transferability of enterococcal R plasmid in mixed culture: among the 28 strains which showed multiple drug resistance, 17 strains transferred all or part of their resistance with $2{\times}10^{-4}-2{\times}10^{-6}%$ of transfer frequency to a plasmid-free recipient, S. faecalis strain JH 2-2.

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Design of a Lightweight Security Protocol Using Post Quantum Cryptography (양자내성암호를 활용한 경량 보안 프로토콜 설계)

  • Jang, Kyung Bae;Sim, Min Joo;Seo, Hwa Jeong
    • KIPS Transactions on Computer and Communication Systems
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    • v.9 no.8
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    • pp.165-170
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    • 2020
  • As the IoT (Internet of Things) era is activated, a lot of information including personal information is being transmitted through IoT devices. For information protection, it is important to perform cryptography communication, and it is required to use a lightweight security protocol due to performance limitations. Currently, most of the encryption methods used in the security protocol use RSA and ECC (Elliptic Curve Cryptography). However, if a high performance quantum computer is developed and the Shor algorithm is used, it can no longer be used because it can easily solve the stability problems based on the previous RSA and ECC. Therefore, in this paper, we designed a security protocol that is resistant to the computational power of quantum computers. The code-based crypto ROLLO, which is undergoing the NIST (National Institute of Standards and Technology) post quantum cryptography standardization, was used, and a hash and XOR computation with low computational consumption were used for mutual communication between IoT devices. Finally, a comparative analysis and safety analysis of the proposed protocol and the existing protocol were performed.

Deep Learning Based Side-Channel Analysis for Recent Masking Countermeasure on SIKE (SIKE에서의 최신 마스킹 대응기법에 대한 딥러닝 기반 부채널 전력 분석)

  • Woosang Im;Jaeyoung Jang;Hyunil Kim;Changho Seo
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.33 no.2
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    • pp.151-164
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    • 2023
  • Recently, the development of quantum computers means a great threat to existing public key system based on discrete algebra problems or factorization problems. Accordingly, NIST is currently in the process of contesting and screening PQC(Post Quantum Cryptography) that can be implemented in both the computing environment and the upcoming quantum computing environment. Among them, SIKE is the only Isogeny-based cipher and has the advantage of a shorter public key compared to other PQC with the same safety. However, like conventional cryptographic algorithms, all quantum-resistant ciphers must be safe for existing cryptanlysis. In this paper, we studied power analysis-based cryptographic analysis techniques for SIKE, and notably we analyzed SIKE through wavelet transformation and deep learning-based clustering power analysis. As a result, the analysis success rate was close to 100% even in SIKE with applied masking response techniques that defend the accuracy of existing clustering power analysis techniques to around 50%, and it was confirmed that was the strongest attack on SIKE.

Antimicrobial Drug Resistance and Transferable Resistance Plasmid in Escherichia coli (대장균(大腸菌)의 항균제내성(抗菌劑耐性) 및 전달성(傳達性) Plasmid)

  • Cho, Dong-Taek;Chun, Do-Ki
    • The Journal of the Korean Society for Microbiology
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    • v.17 no.1
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    • pp.21-34
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    • 1982
  • One hundred and twenty-one strains each of Escherichia coli isolated from stools of 60 patients who received various antimicrobial drugs in hospital for more than one week and apparently healthy 60 students who have no history of taking antimicrobial drugs during recent one month, were tested for their resistance to 13 antimicrobial drugs. The frequency of resistance strains was highest to tetracycline with 69.2%, and followed by streptomycin(Sm), sulfisomidine(Su), chloramphenicol(Cm), ampicillin(Ap), and carbenicillin(Cb) in the decreasing order, ranging from 61.2% to 39.3%. Strains resistant to kanamycin(Km), cephaloridine(Cr), and trimethoprim(Tp) occupied about one-fourth of strains, and only four strains were resistant either one or more of nalidixic acid, gentamicin and amikacin, and no strain was resistant to rifampicin. The frequency of resistant strains to Cm, Ap, Km, Cr, and Cb was much higher among patient isolates than student strains, but strains resistant to the other drugs showed almost the same frequencies between patient and student isolates. There was a marked difference in average minimum inhibitory concentrations of between resistant and susceptible strains, suggesting that the resistance to drugs is the plasmid origin. Seventy-six percent of strains were resistant to one to 10 drugs tested, and no much difference was observed between strains from patients and students. However, strains resistant to four or more drugs were much more frequently found among patient isolates than student strains, with the increasing tendency of multiply resistant strains among patient isolates following the increase in the number of resistant drugs. The transfer of drug resistance by conjugation was tested and 98 strains(67.5%) among 145 which were resistant to two or more drugs were found to transfer their drug resistance to E. coli. Among 74 strains resistant to 7 or more drugs, all except one transferred the resistance, and the number of strains with transferable resistance decreased, as the number of resistant drugs decrease. A R plasmid from randomly selected p13 strain was tested for the incompatibility group, and the plasmid was classified into Inc F II. R plasmM DNA bands were identified by polyacrylamide gel electrophoresis.

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Biocontrol of Isolated Cronobacter spp. (Enterobacter sakazakii) by Heat, Sanitizer, and Antibiotic (열, 살균소독제, 항생제에 의한 분리 Cronobacter spp. (Enterobacter sakazakii) 제어)

  • Lee, Eun-Jin;Park, Jong-Hyun
    • Food Science of Animal Resources
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    • v.30 no.3
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    • pp.479-486
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    • 2010
  • Tolerance against heat, sanitizers, and antibiotics of 112 Cronobacter isolates classified by desiccation was determined to permit effective biocontrol in powdered foods. The isolates were classified into three groups: dry-tolerant (n=37), dry-sensitive (n=7), and dry-intermediate (n=68). The strains that were highly tolerant to drying also showed high heat tolerance that they seemed to have high tolerance to heat after dry stress in powdered foods like infant formula. Sodium hypochlorite and benzalkonium chloride concentrations necessary to achieve a 5-log reduction in viable counts (CFU/mL) were 15-25 ppm and 5-15 ppm, respectively. However, there was little difference of the efficacy of these sanitizers between dry-sensitive and -tolerant strains for planktonic cells suspended in 3% albumin. The minimal inhibition concentration (MIC) of $\beta$-lactam ampicillin was 64-128 ppm for 90% of the strains. The isolates were consistently sensitive to kanamycin and naldixic acid (MIC=4 ppm). Dry-tolerant strains displayed more antibiotic resistance than dry-sensitive strains. The results indicate that dry-tolerant Cronobacter isolates often possess heat and antibiotic resistance, indicated the need for potent sterilization treatments of powdered foods.

Differential Response in Ethylene Evolution and Membrane Permeability Between Rice Cultivars as Affected by Oxyfluorfen (Oxyfluorfen 내성 수도품종의 Ethylene 발생 및 세포막삼투성 차이)

  • 구자옥;이영만
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.33 no.4
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    • pp.375-379
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    • 1988
  • To identify the evidence in tolerance to oxyfluorfen between selected rice cultivars (cv. Chokoto as the tolerant and cv. Weld Pally as the susceptible), the differences in ehtylene evolution, chlorophyll contents and electro-conductivity as affected by various concentrations of oxyfluorfen were assessed. -Under 10$^{-5}$ M oxyfluorfen, the susceptible cultivar showed rapid and higher rate of ethylene evolution, and under 10$^{-4}$ M oxyfluorfen, less difference in ethylene evolution between both cultivars. -Upto 10$^{-6}$ M oxyfluorfen, no difference in chlorophyll contents of both cultivars, however, at 10$^{-5}$ ~10$^{-4}$ M, the susceptible showed as less chlorophyll contents as half of the tolerant. At 10$^{-3}$ M, both cultivars showed complete decomposition of chlorophyll. -At 10$^{-4}$ ~10$^{-3}$ M oxyfluorfen. both cultivars indicate the increased rate in electro-conductivity, and the susceptible cultivar released as much electrolytes as 10% of the tolerant.

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Analysis of Sequence Type and Fluoroquinolone Resistance in Ciprofloxacin-Resistant Escherichia coli (Ciprofloxacin 내성 대장균에서 Sequence Type과 Fluoroquinolone 내성의 분석)

  • Cho, Hye Hyun
    • Korean Journal of Clinical Laboratory Science
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    • v.53 no.3
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    • pp.217-224
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    • 2021
  • Fluoroquinolone (FQ) resistant gram-negative pathogens have emerged worldwide, and the recent increase in FQ resistant Escherichia coli is of great concern in Korea. This study investigated FQ resistance determinants and the epidemiological relationship of 56 ciprofloxacin-resistant E. coli isolated from a tertiary hospital in Daejeon, South Korea from June to December 2018. Molecular epidemiology was investigated by multilocus sequence typing (MLST). Polymerase chain reaction (PCR) and sequence analysis were performed to identify chromosomal mutations in the quinolone resistance determining regions (QRDR) of gyrA, gyrB, parC, and parE and to describe the occurrence of the following plasmid-mediated quinolone resistance (PMQR) genes: aac(6)-Ib-cr, qepA, qnrA, qnrB, qnrC, qnrD, and qnrS. MLST analysis showed 12 sequence types (STs) and the most prevalent ST was ST131 (31/56, 55.4%), followed by ST1193 (13/56, 23.2%), and ST405 (3/56, 5.4%). In 56 ciprofloxacin-resistant E. coli isolates, Ser83→Leu and Asp87→Asn in gyrA and Ser80→Ile and Glu84→Val in parC (51.8%, 29/56) were the most frequent amino acid substitutions and aac(6)-Ib-cr (33.9%, 19/56) was the most common PMQR gene. These results of FQ resistance determinants were more frequently observed in ST131 compared with other clones. Continuous monitoring of the epidemiological characteristics of ciprofloxacin-resistant E. coli isolates and further investigation of FQ resistance determinants are necessary.