• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.2
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• pp.449-454
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• 2010

In this paper, flow characteristics of R600a in an adiabatic capillary tube were investigated employing the homogeneous flow model. The model is based on fundamental equations of mass, energy and momentum which are solved simultaneously. Two friction factors(Churchill) and viscosity(McAdams) are comparatively used to investigate the flow characteristics. Thermodynamic and transport properties of R600a are calculated employing EES property code. Flow characteristics analysis of R600a in an adiabatic capillary tube is presented to offer the basic design data for the operating parameters. The operating parameters considered in this study include condensation temperature, evaporation temperature, subcooling degree and inner diameter tube of the adiabatic capillary tube. The main results were summarized as follows: condensation and evaporation temperature, inlet subcooling degree and inner diameter tube of an adiabatic capillary tube using R600a have an effect on length of an adiabatic capillary tube. The length of an adiabatic capillary tube using R600a is expressed to the correlation shown in Eq. (15).

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.24 no.4
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• pp.436-447
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• 2013

In this paper, Integrated circuit(IC) electromagnetic(EM) conducted immunity measurement and simulation using bulk current injection(BCI) and direct power injection(DPI) methods were conducted for 1.8 V I/O buffers. Using the equivalent circuit models developed for IC electromagnetic conducted immunity tests, we investigated the reliability of the frequency region where IC electromagnetic conducted immunity test is performed. The insertion loss for the noise injection path obtained from the simulation indicates that using only one conducted immunity test method cannot provide reliable conducted immunity test for broadband noise. Based on the forward power results, we analyzed the actual amount of EM noise injected to IC. We propose a more reliable immunity test methods for broad band noise.

• Journal of the Korean Society of Propulsion Engineers
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• v.18 no.5
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• pp.1-11
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• 2014

Sympathetic detonation (SD) of high explosives occurs when a detonating donor initiates neighboring acceptors. The present study focuses on the hydrodynamic simulation of one-on-one sympathetic detonation of 155 mm charge filled with PBXN-109. Both unbuffered and buffered SD configurations are performed while changing the distance between each charge, in order to investigate the detonation sensitivity to a donor initiation. The cause of a SD is by a shock impact for the unbuffered case at a close range, while at a distant range, blast fragment penetration is the primary cause. The buffers can reduce the incident sensitivity to a SD by reducing the strengths of shock wave and impinging fragments.

• Korean Chemical Engineering Research
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• v.56 no.6
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• pp.826-831
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• 2018

This study presents fabrication of bi-compartmental particles labeled by multiple fluorescence. To compartmentalize fluorescent expression at the particle, two fluorescent dyes with less overlap of the excitation and emission spectra are selected. To ensure the fluorescence stability, the fluorescent dyes contain acrylate functional groups in the molecules so that they can be cross-linked together with monomers constituting the particle. Strong fluorescent expression and compartmentalization were observed at the particle fabricated using the selected fluorescent dyes through confocal microscopy. Furthermore, long-term fluorescence stability was verified by measuring fluorescent expression and intensity for 4 weeks. We anticipate that the bi-compartmental particles labeled by multiple fluorescence can be widely used for multi-target drug delivery system, analysis of 3 dimensional Brownian motion, and investigation of 3 dimensional complex self-assembled morphologies.

• Journal of Digital Convergence
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• v.19 no.6
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• pp.91-101
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• 2021

As many CSR activities grow steadily, how charitable giving messages affect donation attitude is received attention. In the current research, temporal orientation and donation recipients is presented an effective variables to judge a organization activities. This article based on CLT theory, we establish the experimental condition focused on interaction effects between two variables: time orientation in charitable activities outcomes(near future: a week vs. far future: a year); and based on the recognizability of recipients(a individual child vs. collective group). Result from study, charitable activities outcomes generated in near future orientation(far future orientation) increase donation attitude and affective when messages are used in a specific(general group) context. Furthermore, empathy of CSR organization is a mediator on donation attitude and affective. We expect that these findings have important implication for charitable giving strategy.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.20 no.6
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• pp.769-778
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• 2007

In this paper, excitation systems using linear mass shaker (LMS) and active tuned mass damper (ATMD) are presented in order to simulate the wind induced responses of a building structure. The actuator force for the excitation systems is calculated by using the inverse transfer function of a target structural response to the actuator. Filter and envelop function are used such that the error between the wind and actuator induced responses is minimized by preventing the actuator from exciting unexpected modal response and initial transient response. The analyses results from a 76-story benchmark building problem in which wind load obtained by wind tunnel test is given, indicate that the excitation system installed at a specific floor can approximately embody the structural responses induced by the wind load applied to each floor of the structure. The excitation system designed by the proposed method can be effectively used for evaluating the wind response characteristics of a practical building structure and for obtaining an accurate analytical model of the building under wind load.

• Journal of Life Science
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• v.25 no.9
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• pp.984-992
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• 2015

Sanguinarine is a benzophenanthridine alkaloid originally isolated from the roots of Sanguinaria canadensis. It has multiple biological activities (e.g., antioxidant and antiproliferative) and immune-enhancing potential. In this study, we explored the proapoptotic properties and modes of action of sanguinarine in human hepatocellular carcinoma HepG2 cells. Our results revealed that sanguinarine inhibited HepG2 cell growth and induced apoptosis in a dose-dependent manner. The induction of apoptosis by sanguinarine was associated with the up-regulation of Fas and Bax, the release of cytochrome c from the mitochondria to the cytosol, and the loss of the mitochondrial membrane potential. In addition, sanguinarine activated caspase-9 and -8, initiator caspases of the intrinsic and death extrinsic pathways, respectively, and caspase-3, accompanied by proteolytic degradation of poly (ADP-ribose) polymerase. Sanguinarine also triggered the generation of reactive oxygen species (ROS). The elimination of ROS by N-acetylcysteine reversed sanguinarine-induced apoptosis. Furthermore, sanguinarine induced the dephosphorylation of Akt and the phosphorylation of mitogen-activated protein kinases, including extracellular signal-regulated kinase (ERK), c-jun N-terminal kinase (JNK), and p38. The growth inhibition was enhanced by the combined treatment of sanguinarine with a phosphatidylinositol 3'-kinase (PI3K) inhibitor and an ERK inhibitor but not JNK and p38 inhibitors. Overall, our data indicate that the proapoptotic effects of sanguinarine in HepG2 cells depend on ROS production and the activation of both intrinsic and extrinsic signaling pathways, which is mediated by blocking PI3K/Akt and activating the ERK pathway. Thus, our data suggest that sanguinarine may be a natural compound with potential for use as an antitumor agent in liver cancer.

• Journal of the Korean Geosynthetics Society
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• v.18 no.4
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• pp.75-85
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• 2019

The lateral load from traffic depends on standard truck's axle loads and locations, loading distance from the inner wall. The method of limit state design has been adopted and used for design of roads in the Republic of Korea since 2015. The concept of equivalent height of soil accounting for traffic loading is often used for design of retaining walls to quantify the traffic loads transmitted to the inner wall faces. Due to the different characteristics of the standard design trucks between Korea and US (AASHTO), the direct use of the guidelines from AASHTO LRFD leads to incorrect estimation of traffic load effects on retaining walls. This paper presents the results of evaluation of equivalent height of soil to reflect the standard truck of the nation, based on the findings from analytical solutions using 3D finite element method. Compare to US, the standard truck loading has a structure where the axle load is concentrated so that the equivalent load height is estimated to be slightly larger than AASHTO for lower retaining wall height. It would be reasonable to present the equivalent load height in Korea more conservatively than AASHTO in terms of securing long term stability of the retaining wall structure.

• Journal of the Korean Geosynthetics Society
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• v.17 no.4
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• pp.119-128
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• 2018

Limit state design has been implemented in Korea since 2015; however, there exists no specification of lateral load determination on retaining wall due to the Korean standard traffic load on retaining wall's backfill surface. The lateral load from traffic depends on lane number, standard truck's axle loads and locations, loading distance from the inner wall. The concept of equivalent height of soil accounting for traffic loadings is typically used for design of retaining walls to quantify the traffic loads transmitted to the inner wall faces. Due to the different characteristics of the standard design trucks between Korea and US (AASHTO), the direct use of the guidelines from AASHTO LRFD leads to incorrect estimation of traffic load effects on retaining walls. This paper presents the results of evaluation of equivalent height of soil to reflect the Korean standard truck, based on the findings from analytical solutions using Bounessq's theory and numerical assessment using 2D finite element method. Consequently, it was found that the equivalent heights of soil from the Korean standard truck load were lower for lower retaining wall height.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.5D
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• pp.831-838
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• 2006

An experimental/analytic study has been conducted to understand the adverse effects of low vehicle speed, high axle load and high tire pressure on the performance of asphalt pavements. Of 33 asphalt sections at KHC test road, two sections having different base layer thickness (180 mm versus 280 mm) are adopted for rollover tests. During the test, a standard three-axle dump truck maintains a steady state condition as moving along the wheel path of a passing lane, and lateral offsets and real travel speed are measured with a laser-based wandering system. Test results suggest that vehicle speed affects both longitudinal and transverse strains at the bottom of asphalt layer (290 mm and 390 mm below the surface), and even slightly influences the measured vertical stresses at the top of subbase and subgrade due to the dynamic effect of rolling vehicle. Since the anisotropic nature of asphalt-aggregate mixtures, the difference between longitudinal and transverse strains appears prominent throughout the measurements. As the thickness of asphalt pavement increases, the measured lateral strains become larger than its corresponding longitudinal strains. Over the limited testing conditions, it is concluded that higher axle weight and higher tire pressures induce more strains and vertical stresses, leading to a premature deterioration of pavements. Finally, a layered elastic analysis overestimates the maximum strains measured under the 1st axle load, while underestimating the maximum vertical stress in both pavement sections.