• Title/Summary/Keyword: 전달단위수

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3-Dimensional Coating Polymer Microneedles for Economical and Efficient Transdermal Drug Delivery (경제적이고 효과적인 경피 약물전달을 위한 3차원 구조의 코팅 고분자 마이크로니들)

  • Lee, Han-Sol;Park, Jung-Hwan
    • Polymer(Korea)
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    • v.38 no.3
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    • pp.391-396
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    • 2014
  • Polymer microneedles can be fabricated by a micromolding method, an easy and cost-effective method. However, it is not easy to achieve uniform coating with an aqueous coating solution due to hydrophobic surface of polymer microneedles. 3-Dimensional coating polymer microneedles could deliver more than twice as much dose as in-plane metal microneedles by increasing coating area and the number of microneedles per unit area. A uniform coating was not obtained by addition of coating additives in the coating solution. The satisfied coating was achieved by treatment of surface of polymer microneedle with metal deposition and UV/ozone, and UV/ozone treatment was an ultimate surface treatment method based on biological safety. Calcein coating polymer microneedles were prepared by using UV/ozone treatment and followed dip-coating, and they delivered calcein in porcine skin successfully after 15 min of insertion.

Design of Decision Support System Algorism for Smart Agricultural Water Information Service (지능형 농촌용수 정보서비스의 의사결정지원 알고리즘 설계)

  • Kim, Sun Joo;Kwon, Hyung Joong;Kim, Phil Shik;Kang, Seok Man
    • Proceedings of the Korea Water Resources Association Conference
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    • 2016.05a
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    • pp.581-581
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    • 2016
  • 물 정보의 대부분은 자연현상과 관련되는 것으로 지속적인 관측과 조사를 통하여 획득된 자료에 의존하며, 최근 정보통신의 발달과 함께 다양한 수문자료를 실시간으로 입수하는 것이 가능하게 되었다. 이와 같은 다양한 수집정보를 필요로 하는 사람들이 정보를 쉽게 입수 할 수 있도록 기술적 지원이 필요하고 국가는 이를 충족시킬 수 있는 정보 서비스 체계를 구축해야 한다. 하지만, 물 관련 정보시스템은 물 정보를 종합적으로 제공하기 보다는 일부 한정된 자료를 대상으로 하고 있고, 표준 체계도 갖추지 못하고 있지 못해 이용하기가 불편하고 정보로서의 가치도 떨어지고 있는 실정이다. 특히, 국내 홍수 및 가뭄재해 정보 제공 시스템은 정보 전달체계가 복잡하고, 각 시스템의 연계성이 부족하여 중복적인 자료를 제공하거나 자료들이 분산되어 있으며, 최신자료의 업데이트가 되지 않아 실질적인 효용성이 떨어지는 시스템이 대부분인 것으로 확인되었다. 또한 재해에 대한 예측 및 대응방안 등 신속한 의사결정 시스템은 현재까지 제공되고 있지 않다. 따라서 홍수 및 가뭄재해에 대한 일원화된 통합 시스템이 요구되며, 재해예방 및 신속한 대처를 위한 의사결정 시스템의 도입이 시급한 실정이다. 이에 본 연구에서는 농촌용수 재해정보서비스의 방향을 정립하고, 의사결정지원 알고리즘 설계를 위한 알고리즘 및 시스템 적용을 위한 예측 평가 기법을 조사하고 분석하여 제시하였다. 본 경구 결과 국토교통부와 기상청의 제공자료를 기초자료로 농림축산식품부의 제공정보를 수정 보완하여 사용할 경우 GIS 기반으로 해정구역 단위, 용수구역 단위로 재해현황 자료 및 전망자료를 제공 할 수 있을 것으로 판단된다.

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Modeling of Microalgal Photosynthetic Activity Depending on Light Intensity, Light Pathlength and Cell Density (빛의 세기, 투과거리 및 세포농도에 따른 미세조류의 광합성 활성 모델링)

  • Yun, Yeong-Sang;Park, Jong-Mun
    • KSBB Journal
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    • v.14 no.4
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    • pp.414-421
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    • 1999
  • The influenced of light intensity, cell density, and light pathlength on photosynthetic activity of Chlorella vulgaris were investigated. Since the light respon curve varied according to reaction conditions, the parameters estimated from nonlinear regression were proved to be apparent and could not be applied to various situations. The light response model incorporating the light penetration through the microalgal suspension was developed based upon the spatial distribution of the photosynthetic activity. This model showed a good agreement with experimental data at different cell densities and light intensities. Using the model the effects of cell density and light pathlenth were simulated and some dicussions about optimization of operation conditions of photobioreactors were carried out. Concludingly, the developed model can be useful for predicting microalgal photosynthesis and for determining the optimal operating conditions.

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Performance of GFR service for TCP traffic in ATM switches with FIFO shared buffer (FIFO 공유 버퍼를 갖는 ATM 스위치에서 TCP 트래픽을 위한 GFR 성능 평가)

  • Park Inyong
    • Journal of Korea Society of Industrial Information Systems
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    • v.10 no.1
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    • pp.49-57
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    • 2005
  • ATM Form has defined the guaranteed frame rate (GFR) service to provide minimum cell rate (MCR) guarantees for TCP traffic in ATM networks and allow it to fairly share residual bandwidth. GFR switch implementation consists of the frame-based generic cell rate algorithm (F-GCRA) and a frame forwarding mechanism. The F-GCRA identifies frames that are eligible for an MCR guarantee. The frame forwarding mechanism buffers cells at a frame unit according to information provided by the F-GCRA and forwards the buffered cells to an output port according to its scheduling discipline. A simple GFR mechanism with shared buffer with a global threshold is a feasible implementation mechanism, but has been known that it is insufficient to guarantee the MCR. This paper has estimated performance of GFR service for TCP traffic over ATM switches with the simple FIFO-based mechanism

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Simulator Development and Analysis for Signal Flow Pathway in Vertebrate Retina (척추동물 망막의 신호 전달 경로 시뮬레이터 개발 및 분석)

  • Baek, Seungbum;Jang, Young-Jo;Cho, Kyoungrok
    • The Journal of the Korea Contents Association
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    • v.18 no.11
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    • pp.655-664
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    • 2018
  • Retina transforms the external light into electrical signal that stimulates visual cortex of the brain. Electrical modeling of the retina is useful to understand its structure and action that is a prerequisite to implement the retina as a hardware device. This paper introduces a 2-D electrical network model of vertebrate's retina considering signal pathway of retinal cells and synapses. We implemented a simulator of the retina based on the electrical network model to analyze its operation under various circumstances. Compared to the prior studies, It might contribute designing of artificial retina device in terms of that this study specifically observed input and output reactions of each cell and synapse node under various light intensity on the retina.

Data Origin Authentication Scheme for Wireless Mesh Networks (무선 메쉬 네트워크를 위한 데이터 송신 인증 기술)

  • Kang, Nam-Hi
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.47 no.7
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    • pp.135-142
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    • 2010
  • Wireless mesh network, which is an access network technology, adopts ubiquitous features of ad-hoc network that includes capabilities of self-configuration and self-management. This paper proposes a scheme which enables nodes along route in wireless mesh network to authenticate data and verify data integrity. The scheme distinguishes infra-node, which is a network device used to form mesh network, and user node in ad-hoc network, which operates functions as a sender, receiver or relayer, to deploy different authentication scheme. That is, hop-based authentication scheme along route forming wireless backbone differs from authentication scheme for user nodes in route over MANET. The proposed scheme is less complex than previously proposed schemes from the repects of security setup procedures and managements. In addition, the scheme is able to reduce transmission delay from a source to a destination owing to fast authentication over wireless backbone.

Numerical Simulation of Heat Transfer in Chip-in-Board Package (Chip-in-Board 패키지의 열전달 해석)

  • Park, Joon Hyoung;Shim, Hee Soo;Kim, Sun Kyoung
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.37 no.1
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    • pp.75-79
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    • 2013
  • Demands for semiconductor devices are dramatically increasing, and advancements in fabrication technology are allowing a step-up in the number of devices per unit area. As a result, semiconductor devices require higher heat dissipation, and thus, cooling solutions have become important for guaranteeing their operational reliability. In particular, in chip-in-board packages, in which chips and passives are embedded in the substrates for efficient device layout, heat dissipation is of greater importance. In this study, a thermal model for layers of different materials has been proposed, and then, the heat transfer has been simulated by imposing a set of appropriate boundary conditions. Heat generation can be predicted based on the results, which will be utilized as practical data for actual package design.

Geomorphological Approach to the Skewed Shape of Instantaneous Unit Hydrograph (순간단위도의 왜곡된 형상에 대한 지형학적 접근)

  • Kim, Joo-Cheol;Jung, Kwansue;Jeong, Dong Kug
    • Journal of Korea Water Resources Association
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    • v.48 no.2
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    • pp.91-103
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    • 2015
  • This paper presents the systematic approach to positively skewed shape of instantaneous unit hydrograph (IUH), that is one of the universal features of hydrologic response function. To this end an analytical expression of statistical moments for IUH is derived within the framework of geomorphologic instantaneous unit hydrograph (GIUH) theory and quantified according to the concept of hydrodynamic, geomorphologic and kinematic heterogeneity. There is a big scale difference between hillslope and channel flow path system. Although the former has the much smaller level of scale its variation coefficient tends to be higher and coefficient of skewness has the different trend than the latter. The shape of IUH is likely to be much more affected by kinematic heterogeneity rather than hydrodynamic heterogeneity and its combined effect with geomorphologic heterogeneity is the major cause of skewing hydrologic response function. Statistical features of hillslope and channel flow path can be transferred into hydrologic response function in the form of dimensionless statistics and their relative importance forms the general shape of hydrologic response function.

Distribution Maps for Waste generation using GIS (GIS 이용 폐기물 발생량 분포지도 작성)

  • Kim, Yi-Hyun;Hong, S. Young;Hong, Seung-Gil;Choe, Eunyoung;Nam, Jae Jak;So, Kyu Ho
    • Journal of the Korea Organic Resources Recycling Association
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    • v.18 no.2
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    • pp.55-61
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    • 2010
  • This study was carried out to analyze national and regional distribution of the organic wastes generation and build their distribution maps including food wastes, paper and wood wastes, wastewater and slaughterhouse wastes. The information for the annual waste production was modified using statistics from Ministry of Environment (MOE). Based on waste generation resources data, we established database architecture table about waste generation. The distribution maps for food wastes were built up in both national and regional scales and distribution maps for paper and wood wastes, wastewater and slaughterhouse wastes were also produced, respectively. The distribution maps of waste generation graphically provide the information regarding biomass resources to policy-makers, farmers, general users and it is highly expected to be utilized for policy-making of environmental-friendly agriculture and bioenergy.

Analysis of water quality smart meter data using dynamic time warping (Dynamic Time Warping을 이용한 수질 스마트미터 데이터 분석)

  • Lim, Soyeon;Jung, Donghwi
    • Proceedings of the Korea Water Resources Association Conference
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    • 2021.06a
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    • pp.173-173
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    • 2021
  • 현재까지 상수도관망 내 수질적 거동에 대한 분석은 (1) 네트워크 수질 모델(EPANET 수질모의 등)에 기반한 방법과 (2) 시공간적 저해상도 데이터에 기반한 데이터 분석법이 주를 이루었다. 그러나 현존 네트워크 수질 모델은 수질 사고의 복잡한 물리·화학적 거동을 상세히 모의하기 어렵다. 반면 계측 및 통신기술의 발달로 고해상도 수질 데이터의 실시간 수집이 가능해지면서 사고의 사전감지, 발생시 즉각적 탐지 및 대응을 위한 데이터 분석법에 관심이 증가하고 있다. 서울 문래동, 인천, 포항의 경우에서도 알 수 있듯이, 수질사고 발생 시 원인물질의 시공간적 이송 또는 전파에 대한 정보는 사고대응에 유용하게 활용된다. 본 연구는, 비정상적인 수질변화의 계통 내 전달 시간을 계산하기 위해 고해상도 수질 스마트 미터 데이터에 기반한 데이터 분석법을 개발하였다. 물공급 하류방향의 수질변화 전달 시간 정량화를 위해 화음탐색법 기반 동적시간워핑(Dynamic time warping; DTW) 기술을 이용하였고, 원데이터의 전처리를 위해 이동평균필터링을 수행하였다. 개발된 분석법은 A시 생산 및 배·급수과정의 감시지점에서 10초 단위로 계측된 다양한 수질변수(pH, 탁도, 잔류염소, 전기전도도, 수온 등)의 공간적 변이 전파시간을 결정하기 위해 적용되었다. 분석에 활용한 데이터는 데이터 통신 및 측정 기기에 의한 이상값과 운영상황의 변화에 따라 변동한 값을 처리하기 이전의 데이터이다. 데이터 품질에 의한 영향을 배제하기 위해 이상값이 발생하지 않은 기간을 파악한 후, 그 기간에 대하여 분석하였다. 계통 내 위계에 따라 두 지점의 측정값의 전파시간을 정량화한 결과, 지점에 따라 전파시간이 다르게 나타났다. 또한, 같은 두 지점에 적용한 결과라도 DTW를 적용하는 기간과 이동평균필터링의 크기에 따라 수질변화 전달 시간이 다르게 나타나는 것을 확인할 수 있었다. 본 연구에서 개발된 분석법은 다변량 수질변수 간의 영향관계를 파악하는데 확장 적용이 가능하다. 또한, 이 방법의 실시간 적용을 통해 동적으로 변화하는 전달시간을 주기적, 공간적으로 갱신하여 관망 수질 변화 모니터링이 가능하다.

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