• Title/Summary/Keyword: 잠재 감염

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Relationship of Environmental tobacco smoke and urinary cotinine levels of passive smokers in their residence (일반 가정에서의 공기 중 nicotine 노출 정도와 간접흡연자의 뇨중 cotinie 농도와의 상관성연구)

  • 김효진;신동천;임영욱;이석주;박성은;양지연
    • Proceedings of the Korea Air Pollution Research Association Conference
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    • 2001.11a
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    • pp.447-448
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    • 2001
  • 최근에는 직접 흡연 뿐만 아니라, 간접 흡연에 의한 인체 유해 영향에 대한 가능성이 공중 보건 문제의 하나로 그 중요성이 증가하고 있다. Brownson등은 1997년 간접 흡연이 폐암의 위험을 증가시킨다는 보고를 하였으며, 간접 흡연은 아동들의 호흡기 질환을 증가시켜 흡연자 가정에 가는 아이들은 비흡연자 가정에 사는 아이들보다 호흡기 감염(기관지염, 폐렴)에 더욱 민감하다고 보고되고 있다(Greenberg, 1988; Zmirou D 등, 1990; Tredaniel J 등, 1989). 따라서 최근에는 간접흡연자들의 환경중 담배연기(ETS) 노출의 잠재적인 건강 영향에 대한 관심이 증가하고 있는 추세이다. (중략)

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치료용 레이저를 이용한 대상포진 (Herpes Zoster)치료 19례에 대한 보고

  • 배성동
    • The Journal of Korean Physical Therapy
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    • v.2 no.1
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    • pp.123-125
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    • 1990
  • 문헌에 의하면 대상포진의 원인은 바이러스에 대한 세포성 면역이 저하될 때, 또는 악성종양 등으로 면역억제제 치료를 받아서 2차적으로 면역이 저하될 때 체내에 잠재해 있던 바이러스가 재활되어 발병하는 것으로 추정하고 있다. 본 저자도 이에 대하여 의견을 같이하고 있는데 노령층의 $60\~70$대 여자환자수가 압도적으로 많았다는 점과, $20\~39$세 사이의 청${\cdot}$장년층에서는 단1명의 대상자가 없다는 점뿐 아니라, 본 대상자중 11세의 소녀는 7세때 뇌종양 수술을 2차례에 걸쳐 실시한 후 면역제제를 계속적으로 사용하는 있는 점 등은 문헌의 발병원인과 상당히 일치하였다. <전파 양식> 비말 감염 (droplet infection)으로 전파되며, 수두와 달리 전염성이 높지 않다. <잠복기> 잠복해 있던 바이러스가 언제 재활할지 알 수 없으므로 불명이다. 그러나 본조사에서는 대상포진에 대한 병력을 가진 사람이 없었고, 발생 원인을 본인 자신도 모르고 있었다. <합병증> Ramsay Hunt의 증후에 의하면 합병증은 외이도의 수포, 안면신경마비, 혀의 2/3부분의 미각상실, 간혹 청각 및 평행장애를 일으킨다고 한다. <치료> 대상포진의 대증요법으로 calamine lotion Burrow solution의 wet dressing 진통제 및 cytosine arabinoside나 adenosine arabinoside와 같은 항히스타인제, 최근에는 Acyclovir가 많이 사용되고 있는 것으로 알려졌다.

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Bacterial Contamination of Dental Unit Water Systems in a Student Clinical Simulation Laboratory of College of Dentistry (치과대학 임상 시뮬레이션 실습실 치과용 유니트 수계의 세균 오염도 조사)

  • Yoon, Hye Young;Lee, Si Young
    • Journal of dental hygiene science
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    • v.15 no.2
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    • pp.232-237
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    • 2015
  • The water supplied from dental unit water systems (DUWS) in dentistry may be heavily contaminated with bacteria and thus may be a potential source of infection for both practice staff and patients. The aim of this study was to evaluate the level of heterotrophic bacteria and to confirm the presence of opportunistic pathogens from DUWS in student clinical simulation laboratory of college of dentistry. Water samples were collected from 36 ultrasonic scalers in student clinical simulation laboratory. The levels of heterotrophic bacteria in water samples were quantified by counting colony forming units (CFUs) on R2A agar media. In addition, opportunistic pathogens were detected by using the polymerase chain reaction (PCR) method. The mean CFUs were 16,095 CFU/ml for water samples and all of water samples exceeded current American Dental Association recommendations of 200 CFU/ml. Pseudomonas species and non-tuberculous Mycobacterium species were detected in the one sample and two samples, respectively, among the 36 water samples by the PCR with specific primers for these bacteria. Our study indicated that DUWS in student clinical simulation laboratory can cause potential infection in students and participants. This study suggested the dental unit water line management and wearing personal protective equipment in student clinical simulation laboratory will be needed to reduce bacterial contamination.

Molecular Epidemiology of Norovirus in Asymptomatic Food Handlers in South Korea

  • Lee, Jeong Su;Jeong, Min Hee;Ju, Si Yeon;Kang, Kyung Ah;Joo, In Sun
    • Journal of Food Hygiene and Safety
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    • v.32 no.6
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    • pp.455-459
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    • 2017
  • Norovirus (NoV) is the most common cause of acute gastroenteritis in all age groups worldwide. In this study, prevalence of asymptomatic norovirus infection was investigated in food handler being employed at food catering facilities in South Korea. A total of 2,729 fecal specimens from asymptomatic food handlers were analyzed, and 1.06% of food handlers (29/2,729) had asymptomatic NoV infection. Of these, 17.2% (5/29) were positive for NoV GI and 82.7% (24/29) were positive for NoV GII. Especially, sequencing and phylogenetic analysis showed that GII-4 was the most prevalent genotype and a large number of asymptomatic food handlers were infested with norovirus GII-4 strains. The results of this study show that asymptomatic food handlers may be potential transmission sources for NoV infection. These results emphasize the need for training of food catering employees about norovirus prevention. Asymptomatic norovirus infection should receive more attention.

Coronaviruses: SARS, MERS and COVID-19 (코로나바이러스: 사스, 메르스 그리고 코비드-19)

  • Kim, Eun-Joong;Lee, Dongsup
    • Korean Journal of Clinical Laboratory Science
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    • v.52 no.4
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    • pp.297-309
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    • 2020
  • Coronaviruses were originally discovered as enzootic infections that limited to their natural animal hosts, but some strains have since crossed the animal-human species barrier and progressed to establish zoonotic diseases. Accordingly, cross-species barrier jumps resulted in the appearance of SARS-CoV, MERS-CoV, and SARS-CoV-2 that manifest as virulent human viruses. Coronaviruses contain four main structural proteins: spike, membrane, envelope, and nucleocapsid protein. The replication cycle is as follows: cell entry, genome translation, replication, assembly, and release. They were not considered highly pathogenic to humans until the outbreaks of SARS-CoV in 2002 in Guangdong province, China. The consequent outbreak of SARS in 2002 led to an epidemic with 8,422 cases, and a reported worldwide mortality rate of 11%. MERS-CoVs is highly related to camel CoVs. In 2019, a cluster of patients infected with 2019-nCoV was identified in an outbreak in Wuhan, China, and soon spread worldwide. 2019-nCoV is transmitted through the respiratory tract and then induced pneumonia. Molecular diagnosis based on upper respiratory region swabs is used for confirmation of this virus. This review examines the structure and genomic makeup of the viruses as well as the life cycle, diagnosis, and potential therapy.

Control of Gray Mould(Botrytis cinerea) on Roses by Pre-and Post-harvest Treatments with Agricultural Chemicals (채화 전.후 약제처리에 의한 절화장미 잿빛곰팡이병 발병억제)

  • Lee, Jung-Sup;Han, Kyoung-Suk;Park, Jong-Han;Cheong, Seung-Ryong;Jang, Han-Ik
    • Research in Plant Disease
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    • v.12 no.3
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    • pp.249-253
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    • 2006
  • Several fungicides such as polyoxine B, fludioxonil, tebuconazole, tebuconazole+dichlofluanid, and fenbuconazole were sprayed once a week on roses in greenhouse. Botrytis infection on stalks was reduced by 71-89% after regular fungicide spray. The reduction of conidial inoculum by these treatments is also observed. The rose petal infections were controlled significantly by these fungicides only 2 days after the application. The development of gray mold on rose flowers harvested just after spray of fludioxonil, tebuconazole and tebuconazole+dichlofluanid were reduced compared to untreated control. This beneficial effect was also shown in flowers artificially inoculated with B. cinerea conidia after harvest. Post-harvest treatments by spraying cut flowers with the fungicides such as iprodine plus thiram, tebuconazole+dichlofluanid and polyoxin D reduced disease incidence by 50-55%.

Head Tilt Associated with Encephalitozoonosis in Four Pet Rabbits (애완 토끼에서 뇌포자육충에 의한 사경)

  • Shin, Jin-Cheol;Kim, Sang-Hun;Kim, Suk;Song, Kun-Ho
    • Journal of Veterinary Clinics
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    • v.32 no.2
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    • pp.212-214
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    • 2015
  • Encephalitoozoon cuniculi is an obligate intracellular microsporidian parasite commonly found in rabbits, causing encephalitozoonosis. This organism can also infect a wide range of hosts including humans, which is known to cause opportunistic infections in immunocompromised individuals. In this case, four rabbits presented with head tilt and nystagmus were diagnosed for E. cuniculi infection using ELISA. The rabbits were treated with fenbendazole for 4 weeks and therapeutic success was evaluated by assessing the neurological symptoms. Three out of 4 rabbits showed improved health condition 3 to 5 days after treatment, but one rabbit showed persistent anorexia and head tilt after treatment and then died after 10 days. This report is the first to investigate the therapeutic response of fenbendazole for rabbit encephalitozoonosis in Korea, and suggests that pet rabbits may serve as potential E. cuniculi reservoirs for both pet animals and humans.

A Study on the Role of Private-led Information Provision: Case of COVID-19 Pandemic (코로나19 팬데믹 상황에서 살펴본 민간 주도 정보제공의 역할 분석)

  • Cho, Hosoo;Jang, Moonkyoung;Ryu, Min Ho
    • The Journal of the Korea Contents Association
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    • v.21 no.4
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    • pp.1-13
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    • 2021
  • With the global pandemic of COVID-19, it is pointed out that exposure to false information to the public could cause serious problems. However, in pandemic situations, there is also an positive effect for the public to share private-led information rather than centralized unilateral delivery of information. This study analyzes the role of private-led information provision in infectious disease situations. To this end, topic modeling and sentiment analysis is carried out on online reviews of all COVID-19-related applications in Google Playstore provided by the Korean government and the private. The results showed that the user's evaluation of private apps, which were used from the early stage of COVID-19, was much higher than the apps provided by the government. In particular, users responded more positively to private apps than government apps in all aspects such as reliability of information, risk avoidance, timeliness, usefulness, and stability. Based on these results, a post-monitoring system is recommended rather than a pre-block of all private apps.

Analysis of Library User Needs in the New Normal Era: Focusing on Social Media (뉴노멀 시대의 도서관 이용자 요구 분석 - 소셜 미디어를 중심으로 -)

  • Park, Tae-Yeon;Oh, Hyo-Jung
    • Journal of Korean Library and Information Science Society
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    • v.52 no.2
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    • pp.303-330
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    • 2021
  • The coronavirus infection-19 (hereinafter referred to as Corona 19) that occurred last year has not been ended until now. There have also been major changes in the library environment. This study focuses on changes in the library environment due to prolonged infectious diseases. In addition, it aims to derive implications for library services in the New Normal era by analyzing changes in user needs over time. For this purpose, we have comprehensively summarized the response activities of libraries due to the spread of Corona 19 in 2020, and analyzed changes in user needs that appeared on social media. Key terms were selected by collecting 496,741 tweets related to libraries in 2019 and 2020, and analysis by year and period by operation type was conducted. Through the analysis, the needs of library users in 2020 were classified into four issues, and the implications for each issue were derived.

Microbial Risk Assessment (미생물학적 위해성 평가)

  • 이건형
    • Korean Journal of Microbiology
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    • v.37 no.2
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    • pp.101-108
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    • 2001
  • Risk assessment defines as the process of estimating both the probability that an event will occur and the probable magnitude of its adverse effects. Chemical or microbial risk assessment generally follows four basic steps, that is, hazard identification, exposure assessment, dose-response assessment, and risk characterization. Risk assessment provides an effective framework for determining the relative urgency of problems and the allocation of resources to reduce risks. Using the results of risk analyses, we can target prevention, reme-diation, or control effects towards areas, sources, or situations in which the greatest risk reductions can be achieved with resources available. Risk assessment is also used to explain chemical and microbial risks as well as ecosystem impacts. Moreover, this process, which allows the quantitation and comparison of diverse risks, lets risk managers utilize the maximum amount of complex information in the decision-making process. This information can also be used to weigh the cost and benefits of control options and to develop standards or treatment options.

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