• Korean Journal of Food Science and Technology
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• v.22 no.4
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• pp.466-472
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• 1990

The effect of sugar addition and heat treatment on the myofibrillar protein extractability was studied. Maillard reaction was dependent on heating time significantly and glucose revealed the highest reactivity for Maillard reaction. The extractability of myofibrillar proteins was lowest in case of glucose addition and decreased according to increasing of heating time, Higher extractability was resulted in by digestion of myofibrillar proteins with enzymes after sugar addition and heat treatment than the undigested samples, as the sample was digested with trypsin that is the highest. And by digestion with trypsin, chymotrypsin and peptidase at a time the extractability of meat proteins increased remarkably.

• The korean journal of orthodontics
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• v.12 no.1
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• pp.61-68
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• 1982

Tooth Positioner는 band를 제거한 후 가능한 빨리 장착시켜야 susceptible하며 무엇보다도 환자의 생리학적 jaw movement를 설정해서 제작해야 하고 적어도 hingeaxis relation은 찾아서 제작해야한다. Positioner의 장착시간은 하루에 $3\~4$시간의 active biting exercise와 수안시간동안 사용하게 한다. 처음 장착시에 가장 tight하고 이 tightness 는 치아가 요망되는 위치로 근접함에 따라서 점차 감소되고 이 tightness의 감소가 작용효과의 가장 좋은 지침이 되며 자는 하루 하루 그 변화를 느껴야 한다. Positioner가 느슨하게 적합되고 좋은 교합관계를 보이면 장착을 수안시간동안으로 제한시키거나 혹은 깨어 있을 동안 한 두시간 장착하게 한아. 대개 $3\~4$주 후에 predetermined pattern과 유사하게 되며, 일반적으로 장착 후 $8\~10$주 후에 더 장착할 것인가를 결정하고 필요성이 없다면 conventional retainer로 바꾸어 준다. Tooth Positioner는 기능적인 구호흡, thumb sucking, snoring을 해소시켜 줄 수 있으며 jaw relationship이나 overbite문제를 해결할 수 있다. 그리고 chair time을 감소시켜 줄 수 있으며 tissue tone을 자극해서 치아위치를 증진시키는데 끊임없이 작용한다. 그러나 제작에 많은 시간이 걸리고 치아를 배열하는 술자의 능력에 따라 치료효과가 많이 좌우되며 너무 bulky하므로 이물감이 커서 유용하게 장착할 수 있는 시간이 제한적이고 natural muscle balance에 대해 간헐적인 교정력을 가함으로써 치아를 loosening 시킬 수 있다. 이 장치물은 다른 removable appliance와 같이 환자의 협조가 무엇보다 중요하므로 환자에게 장착동기를 유발시켜 주는 것이 좋으며 True Blocked Nasal Airway가 있는 환자에게는 금기증이 된다.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1993.04a
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• pp.169-169
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• 1993

동물의 일반활동은 중추신경계에 작용하는 약물에 관한 많은 정보를 제공한다. 따라서 약물의 중추신경계에 대한 독성평가는 물론이고 중추신경계 작용약물의 검색에도 널리 이용된다. 본 연구에서는 여러 가지 기전으로 중추신경계에 작용하는 약물들의 일반활동을 분석하여 중추신경계 작용 약물들의 작용기전에 따르는 일반활동의 특성을 비교 분석하고자 하였다. 실험장치는 UGO BASILE제 활동측정 장치를 이용하였으며, 실험동물은 서울대학교 의과대학 실험동물 사육장에서 사육한 ICR mouse를 사용하였다. 동물의 활동측정은 환경요인을 최소한으로 배제하기 위하여 매일 9:00-11:00 까지 2시간 동안의 행동을 10분 간격으로 측정 기록토록 하였다. 중추신경 흥분제 amphetamine, 진정수면제 phenobarbital, 항불안제 diazepam, 항정신병약 chlorpromazine, 항우울제 haloperidol는 모두 용량 의존적으로 동물의 자발운동에 영향을 미쳤다. 특기할 것은 항불안제 diazepam 은 용량의존적으로 운동 억제를 나타내었으나 진정수면제 phenobarbital의 경우는 용량 의존전 운동억제를 나타내기 이전에 초기약물 유발성 aggressive behavior를 나타내었다. 본 실험결과는 동물의 자발행동의 분석으로 중추신경계 작용약물의 작용기전 규명 및 이에 따르는 약물의 분류 방법으로 유용하게 이용될 수 있을 것으로 생각된다.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1993.04a
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• pp.124-124
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• 1993

녹용은 강심작용, 여성홀몬작용, 강장작용, 창상치유작용 등의 약리작용이 있는 것으로 보고되어 있는데 녹용의 상용량에서는 강장작용, 창상치유작용이 있는 것으로 알려져 있다. 녹용의 창상치유작용은 생체내 질소 평형이 음의 방향으로 되었을 때 이를 빠른 시간내에 정상적으로 회복시키는 약리효과에 기인하는 것으로 볼 수 있겠다. 본 연구에서도 흰쥐에 turpentineee oil (TPO)를 주사하여 acute-phase response를 일으켜 질소평형을 깨뜨린 실험 모델에서 녹용의 효과를 측정하였다. Acute-phase reactants중에서 $\alpha$$_2$-macroglobulin, $\alpha$$_1$-cysteine pretense inhibitor (T-kininogen), ceruloplasmin을 측정 하였는데 이 중에서 creuloplasmin의 측정이 재현성이 높았다. TPO로 급성염증을 유발시키면 2일 후에 ceruloplasmin의 혈청내 농도가 약 100% 증가하며 4일까지 지속하다가 5일째부터 감소하는데 이때 미리 녹용추출물을 투여한 군은 TPO주사 후 4일째에 50% 감소하였다. TPO로 염증을 유발하기 전에 녹용을 투여했을 때가 염증유발 후에 투여했을 때보다 녹용의 효과가 현저히 나타났다. 이러한 결과는 급성염증에 의해 깨어진 단백질 평형을 신속히 정상화시키는 효과가 있음을 나타내는 것으로 이러한 녹용의 효과를 지표로 하여 녹용의 유효성분 분리를 수행하고자 한다.

• Korean Journal of Childcare and Education
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• v.9 no.1
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• pp.101-128
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• 2013

This study investigated the interactions between infants of differing natures and teachers in a nursery, and to find the right way to foster the relationship. This study was carried out for 13 weeks, in a class consisting of eight children between one and two years old and with two teachers. The sources of data collection included observations, interviews with teachers, taking videos and voice recording. The results were as follows. (1) Infants with different natures show different reactions in the same situation and it affects the interaction between them and the teachers. (2) The types of interactions among infants with different natures are distinct and the interaction is influenced by factors other than just their nature. A constant interaction between infants and teachers based on the natures of infants and situational reacting strategies toward infants tremendously influence infants' development.

• Journal of Ginseng Research
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• v.24 no.4
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• pp.202-205
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• 2000

KJHST (Kejihongsarntang) is a modified oriental prescription that consists of five herbs such as Ginseng Radix rubra Koreana, Atractylodis Rhizoma, Zingiberis Rhiaoma, Cinnamomi Ramulus and Glycyrrhizae Radix. For the evaluation of antioxidant and staminal activities of KJHST (Kejihongsarntang), the study was done in comparison of Ginseng Radix rubra (GR). For the antioxidant study, KJHST inhibited hemolysis of erythrocyte and decolored the DPPH(2,2-diphenyl-1-picrylhydrazyl) free radical in a dose depenrlent manner more effectively than GR alone in vitro. KJHST and GR significantly suppressed the time course (1 hr∼6 hr)-level of MDA (malondialdehyde) following AAPH (2,2'-azo-bis-(2-amidino-propane) dihydrochloride) treatment in vivo as compared with control data with no statistical difference. From the evaluation of stamina by swimming test GR and KJHST significantly increased the swimming time in a time and dose dependent manner as compared with control data, while GR was more effective than KJHST in 2 weeks after treatment, though KJHST was more effective than GR at low dose (25 m/kg) 4 weeks after treatment. From the results it can be concluded GR and KJHST had antioxidant and staminal activities.

• Parasites, Hosts and Diseases
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• v.25 no.1
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• pp.24-36
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• 1987

The effect of praziquantel on P. westermani exposed in vitro was observed by stereomicroscope, light microscope and scanning electron microscope. Following results were found. 1. The worms incubated in $0.01{\;}{\mu}g/ml$ praziquantel were moving after 26-hour incubation. However, all of them were immobilized immediately after incubation in solutions over $0.01{\;}{\mu}g/ml$ concentration. 2. All of the exposed worms showed severe vacuolization not only in tegument but in subtegument, intestine, ovary, testis, Mehlis' gland and excretory bladder. 3. Vacuoles in tegument burst out to form craters. As incubation time went on, tegumental structure was disintegrated severely. The worms exposed to praziquantel were observed to be immobilized and be vacuolized of all tissues. Disintegration of reproductive organs suggests that praziquantel have suppressive effect on egg production when the flukes are not killed. The drug effects were found more related with incubation time than with drug concentration.

• Korean journal of food and cookery science
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• v.10 no.1
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• pp.71-75
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• 1994

This study attempted to examine the effect on sensory characteristics and texture of Kyongdan in various volume of adding water and volume of adding salt the most favorite tendency on the guality was at the 25% adding water and 1∼1.5% adding salt. Evaluation was conducted through sensory evaluation and objective evaluation The results were summarized as follows. 1. In sensory evaluation on various volume of water and volume adding salt the most favorite tendency on the gualtity was at the 25vo adding water and 1∼1.5% adding salt. 2. This condition corresponded to the low level of hardness, adhesiveness, gumminess, chewiness and high level of springiness in compa-rison with Instron measurement. In summary the most favorite factor is 12 hours soaking time, 25% adding water (hot water), 1∼1.5% adding salt, over 50 times kneading.

• Phonetics and Speech Sciences
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• v.13 no.4
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• pp.75-87
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• 2021

The purpose of this study was to investigate, longitudinally, interruption behavior which children who do stutter (CWS), children who do not stutter (CWNS) and their mothers and relationship with disfluency of children showed during interactions with their mothers. Subjects for this study consisted of 2-5 year old CWS (male 2 and female 4), an age-matched group of CWNS (male 3 and female 3), and their mothers. Frequencies of normal disfluency (ND) and abnormal disfluency (AD) in children group and frequency of interruption and simultalk duration in children and mothers group were measured two times (initial visit and 12 months later) over the course of one year. As a result, no significant difference was observed in frequency of interruption and simultalk duration both between two mother groups and between two child groups at initial visit and 12 months later. However, frequency of interruption increased significantly over the course of one year in CWS group. A significant group difference was found in frequency of interruption of mothers but, no significant difference was observed in simultalk duration of mothers at initial visit. In the CWS·mothers group, no factors were related with disfluency of children at initial visit and 12 months later. These findings suggest that interruption is not just negative behavior, and that reducing interruption should be considered in child·parent interaction therapy for CWS.

• Journal of The Korean Association of Information Education
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• v.12 no.2
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• pp.141-149
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• 2008

Congruence of figure is a basic to learn a symmetrical figure and helps to understand the characteristics of figure and know the way of drawing figures. The knowledge of congruence provides us art attainments to understand design and fine pieces of art. However, it is difficult to expect the interaction between students or between teachers and students, because of spending too much time for cutting papers and making the shapes of figure during the class for establishing the concepts. This study utilized a question-based interaction model which would foster elementary school student's learning effectiveness and make them understood the concept of congruence, also developed a congruence learning system which could communicate in both synchronous and asynchronous situation.