• Title/Summary/Keyword: 임상 결과 예측

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Combined Effects of Aerobic Exercise Training and Diacylglycerol Ingestion on Blood Lipid Profiles and Resting Metabolic Rate Changes in Obese Man (유산소운동과 diacylglycerol 섭취가 비만인의 혈중 지질성분 및 안정 시 대사량의 변화에 미치는 영향)

  • Lee, Moon-Youl;Paik, Il-Young;Kwak, Yi-Sub
    • Journal of Life Science
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    • v.20 no.8
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    • pp.1261-1267
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    • 2010
  • The aim of this study was to investigate the combined effects of aerobic training and diacylglycerol ingestion on lipid profiles and resting metabolic rate changes in obese men. The subjects were divided into 3 groups: the Diacylglycerol group (D, n=6), aerobic training group (E, n=6), and diacylglycerol ingestion and aerobic training group (DE, n=6). Diacylglycerol was ingested and aerobic exercise training performed for 12 weeks. The information from the research was calculated through a Windows SPSS/PC+ Ver. 12.0K statistics package to standardize the means and deviations for each group. Then, two-way repeated measures ANOVA was used to evaluate the research hypothesis. Percent body fat, blood lipid profiles and resting metabolic rate changes were tested to evaluate the combined effect of aerobic exercise training and diacylglycerol ingestion. The results of this study were as follows; DG ingestion was shown to have a positive effect on body weight and body fat, while having a negative effect on resting metabolic rate changes. However, aerobic training was shown to have a positive effect on all factors including body weight, body fat, and resting metabolic rate. In conclusion, DG ingestion and exercise training were not shown to have synergistic effects on resting metabolic rate changes, percent body fat and lipid profiles, while aerobic exercise training was shown to have a positive effect on resting metabolic rate changes, percent body fat, and lipid profiles. To investigate the therapeutic effect of DG ingestion and aerobic exercise for obese men, analysis of catecholamine, cAMP, HSL, or insulin sensitivity should be considered.

Relationship between Pre-Eruptive Buccal Pit Radiolucency and Restoration in Mandibular First Molar (하악 제1대구치 협측 소와의 맹출 전 방사선 투과상과 수복의 연관성)

  • Jung, Seo-Hyun;Song, Ji-Soo;Shin, Teo Jeon;Hyun, Hong-Keun;Kim, Young-Jae;Kim, Jung-Wook;Lee, Sang-Hoon;Jang, Ki-Taeg
    • Journal of the korean academy of Pediatric Dentistry
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    • v.45 no.1
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    • pp.57-64
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    • 2018
  • Pre-eruptive intracoronal resorption (PEIR) is a developmental defect in the crown of a pre-eruptive tooth. The purpose of this study was to investigate the relationship between the size of the pre-eruptive buccal pit radiolucency, which is suspected as PEIR on a panoramic radiography, and the need for restoration after the eruption of a mandibular first molar. The experimental group included 35 mandibular first molars, in which lesions requiring definite restoration were observed during eruption. The control group consisted of 64 sound mandibular first molars after eruption. The sex, age, tooth position, tooth formation stage, size of the pre-eruptive buccal pit radiolucency, and restoration methods in the experimental group and control group were examined. Compared with the control group, the experimental group showed a statistically significant difference in the size of the buccal pit before eruption. The buccal pit size for predicting the need for restoration was further examined by receiver operating characteristic curve analyses, and the area under the curve was $0.813{\pm}0.047$. If radiolucency is observed at the buccal pit of the mandibular first molar before eruption, periodic observations and post-eruption examinations are required.

Comparison of Vessel Disease and Gensini Score according to Ankle-Brachial Index in Patients with Cardiovascular Disease (심혈관 질환자의 발목-상완 지수에 따른 Vessel disease 및 Gensini score 비교 융복합 연구)

  • Choi, Suk-Kyeong;Choi, Hye-Ran
    • Journal of Digital Convergence
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    • v.15 no.1
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    • pp.267-275
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    • 2017
  • The purpose of this study was to evaluate the clinical availability of ankle-brachial index(ABI) according to severity of cardiovascular disease. The subjects of this study were the patients who had ABI in a general hospital. In this study, total 441 patients were enrolled for analysis. Electric medical records were reviewed to investigate the result of ABI and severity of cardiovascular disease measured vessel disease and Gensini score. Collected data were analyzed using SPSS 21.0 program. Subjects with $ABI{\leq}0.90$ and > 0.90 were classified as having abnormal and normal ABI. There were significant differences in vessel disease categorization($x^2=4.731$, p=.030) and Gensini score(t=2.351, p=.019) between two groups. Therefore, ABI is an effective and non-invasive tool for the diagnosis of cardiovascular disease with high severity. ABI is a valuable predictive index of ischemic heart disease.

Factors Influencing Nursing Practices of Physical Restraint Use among Nurses working in Long-term Care Hospitals (요양병원 간호사의 신체적 억제대 사용과 관련된 간호실무에 영향을 미치는 요인)

  • Ha, Sun-Mi
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.3
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    • pp.526-534
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    • 2019
  • This study was undertaken to identify knowledge, attitude, perception and nursing practice toward use of physical restraints, among nurses in long-term care hospitals. We further explored the impact of factors associated with nursing practice toward use of physical restraints. This was a cross-sectional descriptive study in which self-administered questionnaires were collected from 128 nurses working at 11 long-term care hospitals. Descriptive statistics, including t-test, one-way ANOVA, Welch's test, Pearson correlation coefficients and multiple regression, were applied to analyze the data collected. Our results reveal that the participants possess moderate levels of knowledge, attitude, perception and nursing practice toward use of physical restraints. Significant positive correlations were observed between nursing practice and knowledge. Multiple regression analysis showed that the factors significantly related to nursing practice and use of physical restraint were knowledge (${\beta}=0.27$, p=0.002) and attitude (${\beta}=-0.17$, p=0.044), having a total explained variance of 9.0%. The findings from this study suggest that knowledge is the strongest predictor on nursing practice toward use of physical restraints. Thus, we propose that developing and applying evidence-based educational intervention programs to reduce the use of physical restraints in long-term care hospitals are required.

The convergence Influence of nurse's emotional intelligence, Job Engagement and interpersonal relationship on moral sensitivity (간호사의 감성지능, 직무열의, 도덕적 민감성이 대인관계능력에 미치는 융합적 영향)

  • Bae, Du-Yi;Kim, Hyang-Soo;Kim, Song-Soon;Kim, Yun-Jeong
    • Journal of the Korea Convergence Society
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    • v.10 no.3
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    • pp.93-103
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    • 2019
  • This study is aiming tu clarify the factors that influence the interpersonal relationship of nurses and to use them as basic data for the development of educational programs to help nurse 's interpersonal relationship in the clinical field. The subjects were 179 nurses working at 3 hospitals B city and Y city. The results showed that the interpersonal relationship of the subjects were 3.51 points out of 5 points, emotional intelligence had 3.44 points out of 5 points, job enthusiasm was 3.15 points out of 5 points, and moral sensitivity was 4.5 points out of 7 points. The emotional intelligence (${\beta}=.551$, p = .000) was the predictor for the nurse's interpersonal relationship, and emotional intelligence was 37.3% explained by interpersonal relationship of the nurse. In conclusion, higher emotional intelligence, job engagement, and moral sensitivity of nurses showed higher interpersonal relationship, Emotional intelligence was the factor influencing interpersonal relationship. Therefore, it is necessary to develop an educational program to enhance the emotional intelligence of individual nurses to improve interpersonal skills of nurses.

Influencing Factors of Nursing Performance for Life Care of Delirium Patients among Nursing Students (섬망환자의 라이프케어를 위한 간호학생의 섬망간호 수행 영향요인)

  • Oh, Hyo-Sook;Chang, Mi-Young
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.4
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    • pp.401-410
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    • 2019
  • This study was conducted to identify factors affecting nursing performance of delirium among nursing students. A total of 252 fourth year students were recruited from nursing department in Gwangju. Structured questionnaire was self-administrated from April to September, 2017. The used statistical analysis were t-test, ANOVA, Pearson's coefficient and multiple regression analysis. Knowledge of delirium 29.0±7.24, self-confidence in the care for delirium 71.65±28.55 and nursing performance level for patients with delirium was 41.16±8.97. Nursing performance of delirium had significant positive correlations with delirium knowledge, self-confidence of delirium care. In multiple regression analysis, nursing experience for delirium patients, self-confidence of delirium care, practice experience in intensive care unit, use of nursing diagnosis related to delirium, and satisfaction of clinical practice were significant factors of nursing performance of delirium explaining 29.8% of the variables. In conclusion, to enhance nursing performance of delirium, it is necessary to develop educational program for increasing nursing experience for delirium patients during clinical practice and self-confidence of delirium care.

Nursing Sudents' Experiences of Online Psychiatric Nursing Practice in COVID-19 : A Parse Research Method Study (COVID-19 상황에서 간호대학생의 정신건강간호학 온라인 실습 경험: Parse 연구방법 적용)

  • Gyun-Young Kang;Jinju Kim
    • The Journal of the Convergence on Culture Technology
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    • v.9 no.6
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    • pp.1127-1134
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    • 2023
  • This study is a qualitative study to uncover the meaning and structure of nursing students' online psychiatric nursing practice experience by applying Parse's research method. The subjects of the study were 9 fourth-year nursing students at K University who took psychiatric nursing practice online in the COVID-19 situation. Data collection was conducted from March 7, 2022 to May 27, 2022. As a result of the study, the core concepts of nursing students' online practice experience in psychiatric nursing in the COVID-19 situation were: 'Recognizing the importance of understanding oneself and others', 'Preparing for communication to build therapeutic relationships', and 'A perspective on the future through exploration of the meaning of nursing'. Structural transposition was presented as 'Empathy for self and others', 'Mindset for interpersonal human relationship', 'Exploring the essence of nursing and self-realization'. Conceptual integration appeared as 'Valuing', 'Revealing-Concealing', 'Revealing-Concealing'. In conclusion, nursing students' online practice experience in mental health nursing in the COVID-19 situation was an experience of growing and transcending as future nurses by recognizing the importance of human understanding and communication for the therapeutic relationship that is the purpose of mental nursing. This study will serve as basic data for efficient clinical practice operations in various unpredictable situations, such as future pandemics.

Analysis of Research Trends Related to drug Repositioning Based on Machine Learning (머신러닝 기반의 신약 재창출 관련 연구 동향 분석)

  • So Yeon Yoo;Gyoo Gun Lim
    • Information Systems Review
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    • v.24 no.1
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    • pp.21-37
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    • 2022
  • Drug repositioning, one of the methods of developing new drugs, is a useful way to discover new indications by allowing drugs that have already been approved for use in people to be used for other purposes. Recently, with the development of machine learning technology, the case of analyzing vast amounts of biological information and using it to develop new drugs is increasing. The use of machine learning technology to drug repositioning will help quickly find effective treatments. Currently, the world is having a difficult time due to a new disease caused by coronavirus (COVID-19), a severe acute respiratory syndrome. Drug repositioning that repurposes drugsthat have already been clinically approved could be an alternative to therapeutics to treat COVID-19 patients. This study intends to examine research trends in the field of drug repositioning using machine learning techniques. In Pub Med, a total of 4,821 papers were collected with the keyword 'Drug Repositioning'using the web scraping technique. After data preprocessing, frequency analysis, LDA-based topic modeling, random forest classification analysis, and prediction performance evaluation were performed on 4,419 papers. Associated words were analyzed based on the Word2vec model, and after reducing the PCA dimension, K-Means clustered to generate labels, and then the structured organization of the literature was visualized using the t-SNE algorithm. Hierarchical clustering was applied to the LDA results and visualized as a heat map. This study identified the research topics related to drug repositioning, and presented a method to derive and visualize meaningful topics from a large amount of literature using a machine learning algorithm. It is expected that it will help to be used as basic data for establishing research or development strategies in the field of drug repositioning in the future.

Dental Caries Risk Can Be Predicted by Simply Measuring the pH and Buffering Capacity of Saliva (치아우식과 연관된 타액의 pH와 완충력)

  • Jeong, Soon-Jeong;Apostolska, Sonja;Jankulovska, Mira;Angelova, Dragana;Nares, Salvador;Yoon, Mi-Sook;Lim, Do-Seon;Angelov, Nikola;Jeong, Moon-Jin
    • Journal of dental hygiene science
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    • v.6 no.3
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    • pp.159-162
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    • 2006
  • This study examined the relationship between the quantity of Streptococcus mutans and Lactobacillus spp. related to dental caries and the degree of acidity in saliva. A total of 240 saliva samples were taken from 80 subjects at the faculty of dentistry in Skopje, Macedonia. The saliva samples were taken by stimulating saliva production stimulation with paraffin chewing. However, no stimulation was applied when obtaining the samples used for measuring the pH. The data showed that in the caries group, S. mutans in 1 ml of saliva formed colonies with confluent growth (CFU > $10^6$ and $10^4-10^5$) in 100% of samples, whereas the Lactobacillus spp. formed colonies with confluent growth in 78.3%. In contrast, no colonies with confluent growth (CFU > $10^6$ and $10^5$) were found in the control group (with healthy intact teeth). In the caries group, the pH of the saliva was slightly acidic (pH = 5.90 - 6.50) and the buffering capacity was very low (below 0.7 ml of saliva per min). On the other hand, the pH of the saliva in the control group was neutral (pH 7.01 - 7.7) and the buffering capacity was high (over 1 ml of saliva per min). The increased number of S. mutans and Lactobacillus spp. in 1 ml of saliva (above $10^5$ CFU or more) from the CRT (Caries Risk Test, Vivadent, Liechtenstein) bacteria test can indicate an increased caries risk as well as slightly higher acidity of the saliva. Overall, these results reveal that the caries risk can be predicted by simply measuring the pH and buffering capacity of saliva, and can be used to monitor the effect of dental hygiene practices with the aim of preventing dental caries.

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A Study on the Development of Aerobic Exercise Equipment Design for User-Centered -Focusing on Elliptical Cross Trainer- (사용자 중심의 유산소 운동기구 디자인 개발에 관한 연구 -Elliptical Cross Trainer를 중심으로-)

  • Chung, Kyung-Ryul;Song, Bok-Hee;Yoon, Se-Kyun;Park, Il-Woo
    • Archives of design research
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    • v.19 no.5 s.67
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    • pp.129-138
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    • 2006
  • It is expected that the typical lifestyle of the future will be transformed into an opulent and comfortable existence as the quality of life improves due to the increase in household income and reduction in working hours. In the meantime, as the standard of living becomes increasingly more comfortable and plentiful, the toll on physical health becomes magnified as a result of obesity and insufficient exercise caused by super nutrition and change in labor conditions (from physical labor to mental labor). This has instigated a deep awareness in fitness on the part of many people, forcing them to recognize the significance of daily exercise and physical activity. The high annual growth rate in the fitness and athletic apparatus market, which is more than 20%, is attributed to this phenomenon. The Elliptical Cross Trainer(ECT), which has drawn wide attention recently, is a non-impact athletic apparatus that not only promotes exercise of the upper body parts in such sports as skiing but also the exercise of lower parts of the body on a treadmill. It is a type of cross training athletic gear that has been developed for aerobic exercise throughout the entire body. It has already formed a market as big as that of the treadmill in Europe, America, etc. Recently, its demand is growing sharply in the Korean markets as well as those in Northeast Asian countries, Despite such demand increase and expansion, since most of the expensive ECTs are exclusively supplied by suppliers in only a few advanced countries, localization of the ECT is urgently required in order to enhance competitiveness of Korean manufacturers and to expand the market. This paper introduces the process and results of a design-engineering cooperative study that was peformed for the development of the ECT.

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