• Transactions of the Korean Society of Mechanical Engineers A
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• v.34 no.2
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• pp.167-174
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• 2010

In this study, the optimal position for the backrest pivot of an office chair was investigated by evaluating its performance in terms of the lumbar support and sliding distance of the back from the backrest during tilting motions. The simulation was performed using a mathematical model, which included a human body and a chair. Forty-two backrest pivot points were selected on the sagittal plane around the hip joint of a sitting model. A motion analysis study was also performed using a prototype of an office chair (A-type) with a backrest pivot located on the hip joint of a normal Korean model and a typical office chair (B-type) with its pivot located under the seat. The simulation results showed that both the lordosis angle and the slide distance of the back were minimized when the backrest pivot was positioned close to the hip joint. The experimental results showed that the slide distance and gap between the sitter's lumbar and the backrest was smaller with the A-type than the B-type. Based on the simulation and experimental results, it can be concluded that the backrest can support the sitter's lumbar area more effectively as the pivot position for reclining approaches closer to the hip joint. In this position, the sitter can maintain a comfortable and healthy sitting posture. This paper presents the methods and guidelines for designing an office chair with ergonomic considerations.

• Polymer(Korea)
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• v.36 no.5
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• pp.651-655
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• 2012

Considerable effort has been directed toward the use of silk fibroin as a biotechnological material in biomedical applications on account of its excellent biodegradability, biocompatibility, and unique mechanical properties. For use in tissue engineering, it is very important to design and control the pore architecture of polymeric scaffolds, which provide the vital framework for seeded cells to organize into functioning tissue. In the present study, a silk fibroin scaffold with controlled interconnectivity and pore size was prepared using an electrospinning method with poly(ethylene oxide).

• Transactions of the Korean Society of Automotive Engineers
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• v.18 no.5
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• pp.20-24
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• 2010

The position of the automobile's head restraint is very important for the neck injury in rear end collision. This study is about influence of the head restraint height and distance on neck injury during rear end collision. The effects of the position have been evaluated experimentally. The neck injuries are calculated by the relative acceleration between the upper and lower neck. As a result, It is found that the head restraint should be close enough to the back of the head and high enough to the top of the head.

• Proceedings of the KSME Conference
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• 2000.11a
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• pp.376-380
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• 2000

All chairs are uncomfortable in the long run, but some chairs become uncomfortable more rapidly than others, and in any particular chair, some people will be more uncomfortable than others. Comfort will depend upon the interaction of chair characteristics, user characteristics, and task characteristics. In this study, we intend to design the comfortable office chair by investigating the anthropometric and biomechanical aspects for Korean. Therefore, we determine the design dimensions using the analysis of anthropometric data. With these dimensions, we design the chair mechanism of which backrest reclines with increasing chair pan declination. This mechanism allows the back to get adequate support at the correct level for any backrest declination. Also, the lumbar support in the backrest descends with increasing backrest reclining. By using this chair, a considerably better sitting posture can be obtained, and uncomfortable feeling and back pain may be prevented.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.38 no.4
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• pp.371-377
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• 2014

In tissue engineering, a scaffold is a three-dimensional(3D) structure that serves as a template for regeneration the functions of damaged tissues or organs. Among materials for scaffolds, polycaprolactone(PCL) and ${\beta}$-tricalcium phosphate(${\beta}$-TCP) are biodegradable and biocompatible. In this study, we fabricated 3D PCL, blended PCL (60 wt %)/${\beta}$-TCP (40 wt %), and pure ${\beta}$-TCP scaffolds by a multi-head scaffold fabrication system. Scaffolds with a pore size of $600{\pm}20{\mu}m$ was observed by scanning electron microscopy. The effects of 3D PCL, blended PCL (60 wt %)/${\beta}$-TCP (40 wt %) and pure ${\beta}$-TCP scaffolds were analyzed by evaluating their mechanical characteristics. In addition, in an in-vitro study using osteoblast-like saos-2 cells, we confirmed the effects of 3D scaffolds on cellular behaviors such as cell adhesion and proliferation. In summary, the 3D blended PCL (60 wt %)/${\beta}$-TCP (40 wt %) scaffold was found to be suitable for human cancellous bone in terms of its the compressive strength, biocompatibility, and osteoconductivity. Thus, blending PCL and ${\beta}$-TCP could be a promising approach for fabricating 3D scaffolds for effective bone regeneration.

• 프린팅코리아
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• v.8 no.9
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• pp.54-59
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• 2009

앞으로 환경문제에 대한 대책은 더욱 급속한 스피드로 진행되어 갈 것이다. 그 가운데 품질과의 양립이 중요해지지만, 사용하는 인쇄기의 성능을 최대한 끌어올려 높은 인쇄품질을 실현하려면 사용하고 있는 자재의 밸런스가 좋은 상태를 유지해야 한다. 오존층의 파괴 등 지구 온난화를 비롯한 지구 규모에서의 환경보호에의 대책은 기업이 솔선수범하여 도전할 테마다. 동시에 인체에도 영향이 적은 제품개발이 무엇보다 중요하다. 일반적으로 인쇄는 잉크 또는 롤러와 밀접한 관계를 가지고 있다. 잉크의 특성으로 인해 인쇄물의 건조가 되지 않거나 잉크의 지지도가 나쁘게 되며 세척에 많은 시간을 요구하게 된다면 인쇄 품질을 기대하기는 어려울 것이다. 또한 롤러를 반복적으로 세척하고 새로운 것으로 교체하는 경우에도 작업 능률의 저하를 가져 올뿐만 아니라 작업자의 피로를 유발하여 안전사고 위험에도 쉽게 노출될 수 있다. 이에 이러한 문제점들에 대해 알아보았다.

• Proceedings of the Korean Society of Fisheries Technology Conference
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• 2001.05a
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• pp.126-127
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• 2001

칼슘은 인체의 필수 원소로서 뼈나 치아의 조직에 강도를 부여하는 신체 지지기능 이외에 체액의 pH를 약 알칼리성으로 유지시켜 장관으로부터 흡수한 영양소를 각 세포에 부드럽게 전달하여 세포 및 효소의 활성화에 의한 근육의 수축, 혈액 응고 및 여러 가지 심혈관계 질환의 예방에 관여하는 기능을 한다. 따라서, 칼슘의 흡수가 부족한 경우에는 뼈나 치아의 발육이 나쁘게 되어 성장이 늦고, 피로를 쉽게 느끼며, 고혈압, 심장병 및 뇌졸증 등의 성인병 및 골다공증의 원인이 된다. (중략)

• Transactions of the Korean Society of Mechanical Engineers B
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• v.35 no.11
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• pp.1237-1242
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• 2011

Calcium phosphates are very interesting materials for use as scaffolds for bone tissue engineering. These materials include hydroxyapatite (HA) and tricalcium phosphate (TCP), which are inorganic components of human bone tissue and are both biocompatible and osteoconductive. Although these materials have excellent properties for use as bone scaffolds, many researchers have used these materials as additives to synthetic polymer scaffolds for bone tissue regeneration, because they are difficult to manufacture three-dimensional (3D) scaffolds. In this study, we fabricated 3D calcium phosphate scaffolds with the desired inner and outer architectures using solid freeform fabrication technology. To fabricate the scaffold, the sintering behavior was evaluated for various sintering temperatures and slurry concentrations. After the fabrication of the calcium phosphate scaffolds, in-vitro cell proliferation and osteogenic differentiation tests were carried out.

• Polymer(Korea)
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• v.32 no.5
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• pp.458-464
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• 2008

A successful scaffold should have a highly porous structure and good mechanical stability. High porosity and appropriate pore size provide structural matrix for initial cell attachment and proliferation enabling the exchange of nutrients between the scaffold and environment. In this paper the highly porous scaffold of poly(${\varepsilon}$-caprolactone) electrospun nanofibers could be manufactured with an auxiliary electrode and chemical blowing agent (BA) under several processing conditions, such as the concentration of PCL solution, weight percent of a chemical blowing agent, and decomposition time of a chemical blowing agent. To attain stable electrospinnability and blown nanofiber mats having high microporosity and large pore, a processing condition, 8wt% of PCL solution and 0.5wt% of a chemical blowing agent under $100^{\circ}C$ and decomposition time of $2{\sim}3\;s$, was used. The growth characteristic of human dermal fibroblasts cells cultured in the mats showed the good adhesion and proliferation on the blown mat compared to a normal electrospun mat.

• The Journal of the Korea institute of electronic communication sciences
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• v.11 no.10
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• pp.969-982
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• 2016

Recently, the researches to discovery drug candidates from natural herbs have received considerable attention. In human body, enzyme mostly metabolize the compounds of natural herbs. In this study, we analysis the enzyme interactions using assoication mining. We get this data from BRENDA(: BRaunschweig ENzyme DAtabase) system. Based on enzyme interaction model, we divide the metabolites into substrate metabolites, product metabolites, inhibitor metabolites, and activating metabolites. We then compose substrate metabolite transaction, product metabolite transaction with each metabolites and enzyme interaction transaction with all metabolites. Also we take account of organism for each transactions. We mine frequent metabolites and patterns from six transactions using association rule mining. And we analysis the relationship among metabolites. As a result, we identify the distributions and patterns of metabolites consist in enzyme interactions. We found that metabolites include in only substrate are identified and have very low supports. This results can be useful to develop the effective metabolism prediction model for compounds of natural herbs.