• Title/Summary/Keyword: 인지적 평가

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Pseudoepidemic of Mycobacteria Other Than Tuberculosis (MOTT) Due to Contaminated Bronchoscope (기관지경 오염에 의한 비결핵항산균증의 위발생)

  • Kwak, Seung-Min;Kim, Se-Kyu;Jang, Joong-Hyun;Lee, Hong-Lyeol;Lee, Yi-Hyung;Kim, Sung-Kyu;Lee, Won-Young;Jeong, Yoon-Sup
    • Tuberculosis and Respiratory Diseases
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    • v.40 no.1
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    • pp.29-34
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    • 1993
  • Background: The development of the flexible fiberoptic broncoscope by Ikeda was an important technologic advance in the diagnosis and management of patients with pulmonary disease. But, cross contamination related to fiberoptic bronchoscope was reported in cases involving tubercle bacilli, MOTT and other agents. Therefore, cleaning and disinfecting of fiberoptic bronchoscope requires careful attention. Methods: From September 1991 to May 1992, medical records of all patients with positive culture for MOTT in bronchial washing specimens were reviewed. Also to evaluate bactericidal effect of 2% glutaraldehyde, culture was performed after inoculum of MOTT, Serratia marsescens and Pseudomonas aeruginosa to the disinfectant solution. Results: In 2% alkaline glutaraldehyde, MOTT was not survived only after 30 minute exposure, but P. aeruginosa and S. marsescens were rapidly inactivated with no survivors after exposure to 2% glutaraldehyde. Since vigorous mechanical cleansing and more than 30 minute of contact time within washing machine, no more outbreak was observed. Conclusions: It is also very important that bronchoscopes must be meticulously cleaned after each procedure and more than 30 minute exposure would be required for eradication of MOTT with 2% glutaraldehyde. However even the most strictly applied infection control measures cannot exclude contamination completly and clinicians have to stay alert to this possibility. Prompt detection of pseudoepidemics is possible if abrupt increase in isolation rates, especially if they involve unusual or generally nonpathogenic organisms, are readily recognized.

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Development of Multiclass Assignment For Dynamic Route Guidance Strategy (동적 경로안내전략수행을 위한 다계층 통행배정모형의 개발)

  • Lee, Jun;Lim, Kang-Won;Lee, Young-Ihn;Lim, Yong-Taek
    • Journal of Korean Society of Transportation
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    • v.22 no.7 s.78
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    • pp.91-98
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    • 2004
  • This study focuses on the development of dynamic assignment for evaluation and application for dynamic route guidance strategy. Travelers are classified according to information contents which they received pre/on trip. The first group have no traffic information, so they travel with fixed route. The second group have real-time shortest path and travel according to it. The last group have car navigation system or individual method(cellular phone, PDA-two way communication available) for traffic information on trip. And then they are assigned in accordance with the proposed multiclass dynamic assignment model. At this time the last group is gotten under control with DFS(decentralized feedback strategy). In use of this Process we expect that various traffic information strategy can be tested and also be the key factor for success of ITS, location of VMS(variable message sign), cycle of information, area of traffic information, etc).

The Survey of Children's and Their Parent's Satisfaction for School Lunch Program in Elementary (초등학교급식 운영에 대한 학생과 학부모의 만족도 조사연구)

  • Kim, Eun-Mi;Jeong, Mi-Kyoung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.6
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    • pp.809-814
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    • 2006
  • The satisfaction of elementary school children and their parents with the school lunch program by foodservice system was assessed by questionnaire. The subjects Participated in this survey were 1,136 students, first-6th grade elementary school children and 1,140 parents in Seongnam area. The result was as follows: the satisfaction score for school lunch program by foodservice system was rated as 'high'. Students' and parents' satisfaction score were 3.63 point and 3.62 point (5-point Likert rating scale), respectively. Difference of satisfaction score by grades was that high grade students were significantly lower than low grade students' (P<0.001). Five grade students' score was 3.23 point and 2 grade students' score was 4.04 point. Children's favorite food types were meat, dessert, cooked rice and fried food. The least preferred food types were green and seasoned vegetable, kimchi, soup and fish. Students felt shortage of favorite foods and a lot of dislike foods. Parents answered that thorough sanitary management (22.5%) and use of good quality foodstuffs (11.5%) were the most important factors in improvement of the school lunch program.

Characteristics of Pain Threshold and Pain Experience in Elderly Patients with Dementia (노인 치매 환자의 통증 역치 및 통증 경험의 특성)

  • Bang, Hyeon-Cheol;Park, Ki-Chang;Kim, Min-Hyuk;Lee, Yeong-Bok;Roh, Hyun-Jean
    • Korean Journal of Psychosomatic Medicine
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    • v.21 no.2
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    • pp.140-146
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    • 2013
  • Objectives: We compared the characteristics of the pain threshold and pain experience between demented group and non-demented group. Methods: This study was part of Gangwon projects for early detection of dementia in 2010. We recruited 8302 local resident ages over 65 years old. Of theses, 1259 people who scored low MMSE were selected and 365 of them completed CERAD-K(Consortium to Establish a Registry for Alzheimer's disease). Finally, 90 in non-demented group and 57 in demented group(mild to moderate Alzheimer's disease) were analyzed. Pain threshold was experimentally measured by pressure algometer and we investigated the pain experience, by Brief pain inventory (BPI), a self-report test. Results: In the demographic characteristics, there are more female, higher ages, lower education in the demented group. There was no significant difference between the two groups in the pain threshold. On the BPI results, 'shoulder pain', 'the number of pain' and 'interference of working' were significantly more prevalent in non-demented group. However, there are no significant differences between the groups in the 'pain severity', 'prevalence of pain' and 'pain treatment'. Conclusions: Demented group report less pain experience but, still perceived pain. It support previous studies that patient with dementia have increased pain tolerance but preserved pain threshold. Thus, active pain assessment and treatment for patients with dementia is needed.

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A Comparative Study on Gifted Programs Abroad for Economically Disadvantaged or Minority Students: The Cases of US, UK, Germany, Australia, and Israel (외국의 소외계층 학생을 위한 영재교육 프로그램 비교: 미국, 영국, 독일, 호주, 이스라엘 사례 중심으로)

  • Lee, Shin-Dong;Lee, Kyung-Sook
    • Journal of Gifted/Talented Education
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    • v.25 no.3
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    • pp.439-463
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    • 2015
  • This study compared 14 programs for the economically disadvantaged or minority students with potentials in 5 countries - US, UK, Germany, Australia, and Israel, attempting contents and characters of Korean Head Start to be developed, that is the program for economically disadvantaged gifted students or students from multi-cultural families, who are gifted at risk of under-representation and under-achievement. School wide enrichment programs, which served all students with gifted programs, using RTI model in the pursuit of equity and excellence, turned out to be effective as early interventions and identification implemented for economically disadvantaged or minority students with potentials. Gifted programs for low Social Economic Status (SES) or minority students played a role as a bridge for disadvantaged students to get into a regular gifted program or even higher gifted schools and to have a competency to compete with affluent gifted students. The principles of the programs were acceleration and differentiation. Most programs also ran a parents' education and a mentor program to motivate and support disadvantaged students socially and emotionally. Collaboration among governmental offices and usage of external resources were more effective to support these students and the programs.

The cooling effects of a paddy field area during 2006 summer (2006년 여름철 논에 의한 기온저감효과)

  • Kwon, Sung-Il;Kim, Jin-Soo;Park, Jong-Hwa;Oh, Kwang-Young;Song, Chul-Min
    • Proceedings of the Korea Water Resources Association Conference
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    • 2007.05a
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    • pp.628-632
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    • 2007
  • 본 연구에서는 2006년 여름철(2006년 7월 15일${\sim}$9월 30일) 동안 서로 다른 토지피복형태(논, 밭, 도시녹지대 및 도시주택지)에서의 기온변화 특성을 비교하여 논에 의한 기온저감 효과를 파악하였다. 혹서기 동안 총 3회(2006년 8월 3일, 11일, 15일)에 걸쳐 논으로부터의 거리에 따라 기온을 실측한 결과, 논으로부터 거리가 멀어짐에 따라 기온이 상승하였으며, 170m 지점에서의 기온은 논 지점보다 14시에는 $2.3^{\circ}C$, 22시에는 $1.8^{\circ}C$, 익일 06시에는 $1.3^{\circ}C$ 높게 나타났다. 혹서기 동안 논, 밭, 녹지대, 주택지에서의 열대야 완화효과를 비교해보면, 논이 열대야를 완화시키는 효과가 가장 큰 것으로 나타났다. $25^{\circ}C$이하로 낮아지는 평균시각은 논이 22.36시, 밭이 24.0시, 녹지대가 2.2시, 주택지가 2.3시로 나타났고, 이 시각으로부터의 평균 지속시간은 논이 7.7시간, 밭이 7.3시간, 녹지대가 4.3시간, 주택지가 1.0시간으로 나타났다. 또한 평균 일최저기온은 논이 $23.1^{\circ}C$로서 밭과는 동일하게 나타났으며, 녹지대보다 $0.9^{\circ}C$, 주택지보다 $3.0^{\circ}C$ 낮게 나타났다. 그러나 논과 밭에서의 기온저감효과는 큰 차이를 보이지 않았는데, 이는 기온저감효과가 식생피복상태에 의해 크게 좌우되기때문으로 생각된다. 본 연구에서는 논과 밭에 의한 기온저감효과의 메커니즘은 파악되지 않았으나, 이는 다양한 논지대 및 밭지대를 대상으로 열수지 특성을 분석함으로써 구명할 수 있을 것으로 생각된다.자로서는 제방 마루의 토지이용 및 식생구조, 하도의 식생유형, 하도주변 토지이용, 하안(bank) 형상 및 구조, 수종 및 구조, 하도 및 하안 특징 및 구조 등으로 선정, 검토하였다. 이상의 하천교란과 관계되는 지표를 선정하여 물리적, 생태적 조사 및 교란평가기법(안)을 개발, 제시하였다.EX>)를 보였으며, 그 중 3명에서는 혈역학적으로 큰 의미가 없는 잔여단락이 있었다. 결론: 급성 심근경색증 후 심실중격 결손은 수술위험도가 높은 질환이지만, 수술 전 대동맥내 풍선펌프를 삽입하고 조기에 심실중격 결손부의 infarct exclusion 술식과 함께 관상동맥우회술을 시행함으로써 만족할 만한 수술 및 중기 결과를 얻을 수 있었다.출물 투여로 저하되었으나 NC군보다는 높게 나타났다. 간 중 중성지질 함량은 참나물 에탄올 추출물 투여 용량에 따른 유의차가 없었으나, 총콜레스테롤 함량은 고용량 병합투여한 HC-PBH군만 유의하게 저하되었다. 혈청 및 간 중의 지질 함량 변화는 정상식이를 급여한 NC군과 NC-PB군 간에는 유의차가 없었다. 따라서 고콜레스테롤식이를 급여하면서 참나물 에탄올 추출물을 병합투여 시에만 지질대사 개선 효과가 있는 것으로 여겨지며, 고용량 병합투여 시 효능이 더 큰 것으로 나타났다. 고콜레스테롤식이로 인한 산화적 스트레스가 고콜레스테롤혈증을 유발하였으며, 이는 참나물 에탄올 추출물에 함유된 항산화물질을 포함한 여러 생리활성물질이 영향을 미친 것으로 사료된다. 이상의 실험 결과에서 참나물 에탄올 추출물은 고콜레스테롤식이로 증가된 총콜레스테롤, LDL-콜레스테롤 및 중성지질 함량은 감소시켰고, HDL-콜레스테롤과 인지질 함량은 증가시킴으로써 지방간 및 동맥경화의 예방과 치료에 효과적일 것으로 판단되어 진다./hr/g$, 섭취 7일중 $8.123\;{\mu}g/hr/

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Surface treatment of polysaccharide by flexible active species generator (플렉서블 활성종 발생기를 이용한 다당류 표면처리)

  • Lee, Yu-Ri;Lee, Seung-Hun;Kim, Do-Geun
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2018.06a
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    • pp.39-39
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    • 2018
  • 최근 플라즈마 의학이 발달하면서 제트, 펜, 니들, 토치 등의 다양한 형태의 플라즈마 발생기가 개발되었으며 내부의 가스라인으로 가스의 종류, 유속, 조성 등을 조절하여 생물학적 효과를 극대화 할 수 있고 안정적으로 플라즈마 방전상태를 유지할 수 있으나 처리 면적이 좁아 실제 생물학적 시스템 (세포, 조직, 그리고 박테리아) 적용에 있어 한계점이 존재한다. 이러한 한계점을 극복하기 위해서 유전체격벽방전 (Dielectric barrier discharge, DBD) 방식을 이용한 플렉서블 활성종 발생기를 제작하고 생물학적 시스템에 적용하기 위한 방전 특성 평가를 진행하였으며, 간단한 in vitro 모델인 한천 젤을 이용하여 플라즈마 처리에 따른 전달물질의 침투거리를 확인하였다. 플라즈마 방전 시 생성되는 수산화기 [OH], 과산화수소 [$H_2O_2$], 초산소음이온 [$O_2{^-}$], 오존 [$O_3$], 그리고 산화질소 [$NO_x$]와 같은 산소 및 질소 활성종 (Reactive oxygen and nitrogen species, RONS)은 세포벽 또는 세포막의 주요 구성성분인 다당류와 인지질의 과산화 반응을 통해 구조를 변화시키고 생물학적 시스템의 표면의 pH를 낮춘다. 이러한 RONS의 작용은 살균, 소독 뿐만 아니라 약물의 침투를 돕는다. 일반적으로 한천 겔은 농도에 따라 생체 내 뇌 조직과 물리적 특성이 유사하고, 미생물학 기질, 방사선학 연구를 위한 조직모델로 사용되기 때문에 본 연구에서는 3%와 5% 농도의 한천 젤을 사용하여 침투거리를 확인하였다. 한천 젤은 $2.5{\times}2.5{\times}2.5cm^3$의 크기로 준비되었고 대조군으로 염료가 포함된 에멀젼을 0.01 g 도포하고, 실온에서 30분간 보존 후 단면을 잘라 현미경으로 침투거리를 확인하였으며, 실험군으로 플라즈마 전처리 후 에멀젼을 도포한 시표와 에멀젼 도포 후 플라즈마 처리한 시료에 대해 에멀젼 침투거리의 변화를 확인하였다. 본 연구의 플렉서블 활성종 발생기는 인체에 부착하여 사용되기 때문에 화상, 홍반을 유발을 방지하기위해 $40^{\circ}C$의 온도에서 실험을 진행하였고 이때에 플라즈마 방전조건은 $0.065W/cm^2$ 수준의 전력을 소모하는 1.7 kV의 전압, 16 kHz의 주파수로 10분간 처리하였다. 그 결과 3%의 한천 젤의 경우 침투거리 0.779 mm에서 0.826 mm, 0.942 mm까지 침투거리가 증가하였고 5%의 한천 젤의 경우 0.859 mm, 0.949 mm로 증가하였다. 이러한 침투거리 증가는 젤 표면의 다당류를 구성하고 있는 단량체가 플라즈마 처리시 화확적 구조가 끊어져 결론적으로 약물 침투가 증가된 것으로 판단된다.

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Amyloid-β Levels in Mice Hippocampus According to the ALDH2 Enzyme Activity followed Ethanol Exposure for 8-Weeks (ALDH2 효소 활성과 8주간 에탄올 노출에 따른 해마조직의 아밀로이드 베타 발현)

  • Moon, Sun-In;Eom, Sang-Yong;Yim, Dong-Hyuk;Song, Sun-Ho;Kim, Yong-Dae;Kim, Heon
    • Journal of Life Science
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    • v.21 no.11
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    • pp.1636-1640
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    • 2011
  • Alzheimer's disease (AD) is a progressive neurodegenerative disease, resulting in the loss of cognitive function. Mitochondrial aldehyde dehydrogenase (ALDH2) has been proposed to be a risk factor for the development of AD, but there is still controversy about that. In this study, we demonstrated the role of ALDH2 enzyme activity on amyloid-beta (A${\beta}$) and nuclear factor kappa B (NF-${\kappa}B$) expression in mice brain following ethanol exposure for 8 weeks. Five male Aldh2 (+/+) and Aldh2 (-/-) mice, 8 weeks-old of age (C57BL/6J strain), in each group were exposed to ethanol for 8 weeks (2 g/kg wt./day) using gavage. Those in the control groups received 0.9% saline alone. Results showed a difference in expression level of A${\beta}$ in the hippocampus after ethanol exposure according to the ALDH2 enzyme activity (p<0.05), but not in the level of NF-${\kappa}B$). Our results suggest a possibility that ALDH2 enzyme activity may be an important role in the development of AD.

A Study on the Elaboration of Request for Proposal of Localization Parts using AHP method (AHP 기법을 적용한 부품국산화 제안요청서 정교화 연구)

  • Song, Hyeong-Min
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.1
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    • pp.35-44
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    • 2020
  • The purpose of this study is to elaborate the request for proposal (RFP) for the localization parts development support project of core parts carried out by the Defense Agency for Technology and Quality. The RFP is the most important document throughout the localization parts project, including project announcement and developer selection, design and test of the development product, final evaluation, and standardization of the project. However, if the RFP is not established at the beginning of the project, there is an increased risk of business failure due to frequent changes by various reasons. In this study, we recognized the necessity of elaboration of RFP and applied the AHP method for quantitative elaboration. Eight requirements of the RFP related to the mechanical/electrical performance of localized development products and three elaboration methods for each requirement were designed in a hierarchical structure, and each weight was calculated by applying the 5-point scale AHP method. The AHP survey was conducted with 20 developers participating in the localization parts project, and the consistency ratio of the AHP survey result was less than 0.1. The elaboration method with the highest value among the calculated weights is classified, and the analysis results and future research directions of the elaboration method are presented.

Development and Validation of the Parental Role Responsibilities Scale (부모의 양육 역할 책임 척도 개발 및 타당화 연구)

  • Hwang, Ock-Kyeung;Jung, Youn-Ah;Song, Mi-Ryoung;Myung, Jun-Hee
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.2
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    • pp.440-451
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    • 2021
  • The purpose of this study is to develop and validate the parental roles and responsibilities for young children. A survey was conducted on 301 parents with children attending preschools. The parental roles and responsibilities scale were determined from a total of 60 items and 11 sub-factors based on the criteria for goodness, validity, and reliability of items (i.e., factor load ≥ 0.5; AVE ≥ 0.5; CR ≥ 0.7; Cronbach's alpha ≥ 0.7). The parental roles and responsibilities scale include 'hygiene management' (4 items), 'physical activities' (6 items), 'survival and health care' (6 items), 'cognitive development' (5 items), 'emotional stability' (5 items), 'social skills' (6 items), 'social norms and values' (7 items), 'physical environment' (5 items), 'protection' (5 items), 'family community consciousness and family tradition' (4 items), and 'the role and responsibility of parents for childcare institutions' (7 items). It is significant that the indicators on the parental roles and responsibilities for young children were developed and verified to fit the situation in Korea. Findings will help identify the characteristics of parental role responsibilities and serve as a basis for efficient communication between parents and preschoolers.parental role responsibilities and serve as a basis for efficient communication between parents and preschools.