• Title/Summary/Keyword: 인지저하

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Behavioral Variant Frontotemporal Dementia Phenocopy Syndrome (행동증상 아형 전측두엽 치매 표현형모사 증후군)

  • Cheon, Jin Sook
    • Korean Journal of Psychosomatic Medicine
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    • v.25 no.1
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    • pp.3-11
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    • 2017
  • Objectives : The aim of this study was to draw attention toward so called 'behavioral variant frontotemporal dementia(bvFTD) phenocopy syndrome', which is difficult to discriminate with the primary psychiatric disorders, showing poor response to conventional therapeutic drugs, leading to higher risk to misdiagnoses and legal problems. Furthermore, the author insisted that our interest and study on them must be continued. Methods : English articles published during 2000 thru 2016 had been searched by internet with the combination of words such as 'frontotemporal', 'phenocopy' and 'behavioral', and reviewed. Besides, two clinical vignettes were described. Results : Precise diagnosis is important because patients' behavioral symptoms can influence on their families and community. However, disease-modifying treatment for bvFTD are not developed until now, and recent therapeutic drugs are only good for specific symptoms, while deterioration progresses in spite of proper psychiatric management. The possible bvFTD patients are not progressed into probable bvFTD clinically, showing no decline of cogntive and social function, no decrease of activity function, longer survival time, and normal neuroimaging for several years. Conclusions : Rather than expected, there are much more patients having clinical symptoms, course and diagnostic findings including neuroimaging, which are atypical to classical frontotemporal dementia and primary psychiatric disorders. If our knowledge and discriminating ability is improved, discovery rate of that cases will be increased. However, the identity of these atypical features are not clarified until now, it must be further actively investigated.

A Study on the Determinants of the Incidence and the Transition of Older Adult Disability: Findings from the Korea Longitudinal Study of Aging(KLOSA) (노년기 장애발생과 장애정도의 변화에 미치는 영향요인 연구: KLOSA 1차와 2차 자료를 중심으로)

  • Koo, Bonmi;Seok, Jae Eun
    • 한국노년학
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    • v.32 no.4
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    • pp.993-1011
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    • 2012
  • The purpose of this study is to investigate the factors associated with the incidence and the transition of disability among Korean older adults. Samples consist of 1,454(42.7%) men and 2,032(58.3%) women aged 65 and over who participated in the 1st and 2nd wave of the Korea Longitudinal Study of Aging: KLOSA. To estimate the level of disability, ADL and IADL disability indexes are used. As the results, major risk factors for ADL/IADL disability incidence include injury, vision problem, cognitive function, depression, health behavior, socioeconomic characteristics and age. Among the normal older adults, the odds ratio of having dementia symptoms at 2nd wave(2008) are 2.0 times greater for the older adults who have less cognitive function than those who don't have at 1st wave(2006). Among the older adults with chronic diseases, the odds ratio of having disability at 2nd wave are 1.8 times greater for the older persons who have depression than those who don't have at 1st wave. Secondly, concerning the predictors affecting the disability transition among the disabled older adults at 1st wave, the likelihood of remaining at the same level or deteriorating the level of IADL disability, as compared with improving the level, is associated with having less instrumental support or being older. These results indicate that it is necessary to prefer multilevel intervention in order not only to prevent the incidence of disability, but also to prolong the deterioration of disability in the older adults.

Analysis on the Effect of Lessons with the GIS Application in Teaching and Learning of Geography of Elementary School (초등학교 지리학습에 있어서 GIS 활용수업의 효과분석)

  • Park, Soon-Ho;Jung, Eun-Ju
    • Journal of the Korean association of regional geographers
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    • v.14 no.3
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    • pp.269-278
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    • 2008
  • This research analyzed the effect of lessons with the GIS application as an alternative scheme of teaching and learning of geography in elementary school. Two classes in the third grade at Y elementary school in Andong were selected to conduct lessons on 'The Landscape of My Hometown' from March 6 through June 30, 2006. In the experimental class, the lessons were conducted with the GIS application; while, in a comparative class, the lessons were carried with usual teaching and learning method. To find out the effect of lessons with the GIS application, differences of spatial cognition of students were figured out between groups, and before and after lessons. The difference between the spatial concept development stages and materials on the textbook discouraged students to pursue their learning as well as made them hard to achieve the goals of lessons. The GIS application had been suggested as an alternative teaching and learning method to overcome the difference; however, it has been hard to find any empirical research to verify the effect of the lessons with GIS application in elementary school. The ability of spatial cognition of the third graders at an elementary school was very low as the result of that curricula in the first and second grades dealt with sketch maps as teaching and learning media. The map learning of third grader on the transitional stage would play the critical role to develop the spatial cognition ability in the future. The field study contributing to developing spatial cognition ability would not be conducted at school. It was required to have the alternative learning schemes such as lessons with GIS application. The lessons with GIS application verified effect of GIS application as the alternative method. The GIS application helped students to recognize landmarks, directions and distance effectively as well as reduced the spatial cognition difference among individuals and/or groups.

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The Effects of Sleep Apnea and Variables on Cognitive Function and the Mediating Effect of Depression (수면무호흡증과 수면변수가 인지기능에 미치는 영향과 우울증의 매개효과)

  • Park, Kyung Won;Kim, Hyeong Wook;Choi, Mal Rye;Kim, Byung Jo;Kim, Tae Hyung;Song, Ok Sun;Eun, Hun Jeong
    • Sleep Medicine and Psychophysiology
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    • v.24 no.2
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    • pp.86-96
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    • 2017
  • Objectives: This study aimed to analyze causality among sleep apnea, depression and cognitive function in patients with obstructive sleep apnea. Methods: We reviewed the medical records of 105 patients with sleep apnea and snoring who underwent overnight polysomnography (PSG). We analyzed various biological data, sleep variables (sleep duration and percentage) and respiratory variables [arousal index (AI), periodic leg movement index (PLM index), snoring Index (SI), mean SpO2, minimum SpO2, apnea-hypopnea index (AHI), and respiratory disturbance index (RDI)]. We also analyzed various data by sleep, cognition, and mood related scales: Pittsburgh sleep quality index (PSQI), Epworth sleepiness scale (ESS), snoring index by scale (SIS), Montreal Cognitive Assessment-Korean (Moca-K), Mini-mental State Examination-Korean (MMSE-K), clinical dementia rating (CDR), and Beck Depression Inventory (BDI). We analyzed causation among sleep, and respiratory, mood, and cognition related scales in obstructive sleep apnea patients. We analyzed the mediating effects of depression on sleep apnea patient cognition. Results: As Duration N1 increased and Total sleep time (TST) decreased, MOCA-K showed negative causality (p < 0.01). As BDI and supine RDI increased, causality was negatively related to MOCA-K (p < 0.01). As PSQI (p < 0.001) and SIS (p < 0.01) increased and as MMSE-K (p < 0.01) decreased, causality was positively related to BDI. BDI was found to mediate the effect of age on MOCA-K in patients with obstructive sleep apnea. Conclusion: Duration N1, total sleep time, BDI, and supine RDI were associated with cognitive function in obstructive sleep apnea patients. Depression measured by BDI partially mediated cognitive decline in obstructive sleep apnea patients.

Effects of a Short-term Multimodal Group Intervention Program on Cognitive Function and Depression of the Elderly (단기 집단 복합중재가 정상 노인의 인지기능 및 우울에 미치는 영향)

  • Jung, Beom-Jin;Choi, Yu-Jin
    • Therapeutic Science for Rehabilitation
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    • v.8 no.3
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    • pp.57-68
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    • 2019
  • Purpose: This study aimed to investigate the effects of a short-term group multimodal intervention program that mixes physical activity, cognitive motion, and social interaction, on the cognitive function and depression level of healthy over 75-year-old individuals. Method: This study used a one group pre-test-post-test design, and intervention was made for 70 minutes per session, once a week, for four sessions in total. To compare changes in cognitive function, depression level and physical function before and after intervention, this study used the Mini-Mental State Examination-Dementia Screening (MMSE-DS), Geriatric Depression Scale-Short Form (GDS-SF), and Berg Balance Scale (BBS). Result: After applying group multimodal interventions to healthy over 75-year-old individuals, there was a statistically significant improvement in their cognitive function (p < 0.01), and there was a statistically significant decrease in their depression level (p < 0.05). Also, there was an increase in the rating score of the degree of balance from $46.83{\pm}9.11$ points before the intervention, to $48.08{\pm}7.00$ points after the intervention; however, it was not statistically significant (p > 0.05). Conclusion: Short-term group multimodal intervention that mixes physical activity, cognitive motion, and social interaction had a significant effect on slowing down the deterioration of cognitive function in healthy over 75 year-old individuals, and decreased their depression level. This study is significant in that it presents a foundation for providing more systematic intervention for the prevention of dementia and depression in the healthy older individuals. Follow-up studies should verify the result through research on the effects of an occupational therapist's professional treatment, and experimental group-control research.

The Effect of Visual and Hearing Impairment on Depression and Cognitive Function in Community-dwelling Elderly : The Korean Longitudinal Study of Aging 2008 (노인의 시력 및 청력 저하가 우울 및 인지기능에 미치는 영향: 2008년 고령화연구패널조사)

  • Kim, Hee-Jeong;Kim, Bo-Hye;Kim, Ok-Soo
    • Korean Journal of Adult Nursing
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    • v.23 no.6
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    • pp.584-594
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    • 2011
  • Purpose: The purpose of this study was to identify the prevalence of visual and hearing impairment and to investigate the effect of visual and hearing impairment on depression and cognitive function in community-dwelling Korean elderly. Methods: The study population consisted of a representative community sample of 4,028 persons aged 65 and older from the Korean Longitudinal Study of Aging 2008. Depression and cognitive function were measured by CES-D 10-item scale and K-MMSE. Visual and hearing impairment were measured by 5-Likert scale. Data were analyzed using Rao-Scott ${\chi}^2$-test, simple and multiple logistic regression. Results: The prevalence of visual and hearing impairment were 37.3% and 14.0%, respectively. Of the participants, the prevalence of depression was 58.4% and cognitive impairment was 50.6%. There were significant differences in depression and cognitive function according to visual and hearing impairment. Far vision and hearing impairment were predictors for both depression and cognitive impairment even after covariates had been adjusted. Conclusion: These data suggest that visual and hearing impairment in older adults may increase their probability of experiencing depression and cognitive impairment. Thus sensory impairment should be considered a risk factor for mental health and the cognitive function of elderly.

Simple Frame Marker: Implementation of In-Marker Image and Character Recognition and Tracking Method (심플 프레임 마커: 마커 내부 이미지 및 문자 패턴의 인식 및 추적 기법 구현)

  • Kim, Hye-Jin;Woo, Woon-Tack
    • 한국HCI학회:학술대회논문집
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    • 2009.02a
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    • pp.558-561
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    • 2009
  • In this paper, we propose Simple Frame Marker(SFMarker) to support recognition of characters and images included in a marker in augmented reality. If characters are inserted inside of marker and are recognised using Optical Character Recognition(OCR), it doesn't need marker learning process before an execution. It also reduces visual disturbance compared to 2D barcode marker due to familarity of characters. Therefore, proposed SFMarker distinguishes Square SFMarker that embeds images from Rectangle SFMarker with characters according to ratio of marker and applies different recognition algorithms. Also, in order to reduce preprocessing of character recognition, SFMarker inserts direction information in border of marker and extracts it to execute character recognition fast and correctly. Finally, since the character recognition for every frame slows down tracking speed, we increase the speed of recognition process using the result of character recognition in previous frame when frame difference is low.

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Dwelling Depression Measurement Based on Image Analysis Modeling: Focusing on K-HTP (이미지분석 모델링 기반 고령자 주거우울 측정 연구 -K-HTP를 중심으로-)

  • Lee, Yewon;Park, Chongwook;Woo, Sungju
    • The Journal of the Convergence on Culture Technology
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    • v.4 no.3
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    • pp.1-6
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    • 2018
  • With the increase of the elderly population, demand for improvement of quality of life and measurement of mental state has increased. However, much of the self-reported diagnosis does not reflect cognitive impairment. This study aims to measure the dwelling depression by applying K-HTP and verify the validity. 301 persons over 65 years old who live as single and couple households in Daejeon and surrounding districts were surveyed during 22 January to 2 February, 2018. The correlations between the dwelling depression and K-HTP are clarified and the validity was evaluated. The correlations between the geriatric dwelling depression index(GDDI) and the GDDI based on K-HTP(GDDI-K) are clarified and the accuracy was analyzed. The results showed that the K-HTP can be utilized to measure the dwelling depression. We suggested a new measurement tool and provide further benefits for researches on diagnoses using the projective method.

A Study on the Daylight Illumination Environment of a Classroom and a Glare Phenomenon on the Blackboard (교실의 주광 조명환경과 철판의 눈부심 현상에 관한 연구)

  • 임윤빈;장우진
    • Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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    • 1996.11a
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    • pp.42-48
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    • 1996
  • Glare phenomenon by sun's altitude and strong sunlight make a much visual handicap. And so, it reaches to unreadable situation although enough illumination in the fore site student of a window site and passage site. In school student seat arrange in the order of their height. So, cause the eyesight acuity according to distance is different, eyesight of backseat's student drop 1.0 and less in spite of 1.0, a learning effect reduces rather then that of the fore site student for site and Passage sitestudents. Therefore. in school, the conclusion's alteration of school structure, position's alteration and material quality's improvement of blackboard are needed, should be local lighting in blackboard. Therefore, we think that in other in improve the effect of lesson by the student, the student seats are not given by uniform disposition in the order of their height but change by a specified period.

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The Detection of Intracranial Calcification by MR : Experimental Model (실험적 모델을 이용한 자기공명영상에서 석회화의 인지)

  • 박승진
    • Progress in Medical Physics
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    • v.5 no.1
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    • pp.3-12
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    • 1994
  • Purporse : It is known that detection of calcification by MRI is difficulty in intracranial calcified lesions, but author tried to evaluate the signal intensity image of calcification by MR with experimental model. Subjects & Methods : Author analyzed and compared with values of calcium carbonate and hydroxyapatite phantoms by each concentration (10, 20, 30, 40, 50%) and size(1-10mm), measured ROI attenuating from CT and MRI(TlWI & T2WI). Results : The high concentration of calcium carbonate is, the lower the signal intensity of calcium carbonate phantom is both T1 & T2WI. For concentration of Hydroxyapatite of up to 30% by weight the signal intensity on standard T1 weighted images increased but subsequently decreased. Hyperintensity does not preclude calcification as a cause of the signal alteration-an observation that all radiologists interpreting MR images need to be aware of. Conclusion: The signal intensity of intracranial calcification is various on MR imaging in concerning with components, concentration, & size of calcification, and especially high signal intensity of intracranial calcification noted differencial diagnosis.

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