• Title/Summary/Keyword: 인지저하

Search Result 520, Processing Time 0.033 seconds

Comparing Construct and Predictive Validities of the Measurement of Children's Approximate Number Acuity Depending on Numerosity Comparison Task Format (수량 비교 과제의 형식에 따른 아동의 수 민감도 측정치의 구성 타당도 및 예측 타당도 비교)

  • Park, Yunji;Cho, Soohyun
    • Korean Journal of Cognitive Science
    • /
    • v.25 no.2
    • /
    • pp.159-187
    • /
    • 2014
  • Approximate number sense(hereafter, ANS) is the ability to compare and operate upon numerosity information. The numerosity comparison task is used to measure ANS. However, there is considerable variance among previous reports of ANS acuity which may be related to different task formats used. Here, we aim to investigate whether the format of the numerosity comparison task influences measurements of ANS acuity. We compared two task formats; 1) an intermixed format presenting two intermixed arrays of black and white dots, and 2) a side-by-side format showing two arrays of dots side by side. The intermixed format likely makes additional demands on general cognitive resources for inhibitory control, selective attention, or visuospatial working memory. The performance on the intermixed format was significantly lower than that of the side-by-side format resulting in an underestimation of ANS acuity compared to the expected trajectory of ANS development. In addition, the ANS acuity measured from only the side-by-side format was correlated with children's mathematical achievement and age. Our results demonstrate that measurement of ANS from the side-by-side format has higher construct and predictive validity compared to that of the intermixed format.

Effect of Stereotype Threat on Spatial Working Memory and Emotion Recognition in Korean elderly (노화에 대한 고정관념 위협이 노인의 공간 작업기억 및 정서인식에 미치는 영향)

  • Lee, Kyoung eun;Lee, Wanjeoung;Choi, Kee-hong;Kim, Hyun Taek;Choi, June-seek
    • 한국노년학
    • /
    • v.36 no.4
    • /
    • pp.1109-1124
    • /
    • 2016
  • We examined the effect of stereotype threat (STT) on spatial working memory and facial emotion recognition in Korean elderly. In addition, we investigated the role of expected moderator such as self-perception of aging. Seventeen seniors (male=7) received basic cognitive tests including K-WMS-IV, MMSE and answered self-report questionnaires including self-perception of aging, anxiety of aging, attitude toward aging and age identity on the first visit. On the second visit, they were exposed to negative stereotype by reading a script detailing cognitive decline related to aging while a control group was exposed to a neutral content. Following the exposure, they were tested on a spatial-working memory task (Corsi-block tapping task) and emotion recognition task (facial expression identification task). The results showed that the seniors exposed to STT showed significantly lower performance on emotion recognition task (p < .05) (i.e., especially on the more difficult facial stimuli). In addition, there was a significant interaction between STT and self-perception of aging (p< .05), indicating that those who have positive self-perception of aging did not show impairment in emotion recognition task and difficult spatial working memory task under STT. On the other hand, those with negative self-perception of aging showed impaired performance under STT. Taken together, the current study suggests that being exposed to STT could negatively influence cognitive and emotional functioning of elderly. Interestingly, having a positive self-perception of aging could protect the underperformance caused by STT.

Survey and Analysis of Vitality of the Senior to Safe Driving License in Korea (한국의 고령자 생체능력 조사로 안전한 운전면허 적성검사 강화 연령 추정)

  • Lee, Jun;Bang, Han-Nah;Lee, Sang-Jo
    • Journal of the Society of Disaster Information
    • /
    • v.18 no.3
    • /
    • pp.622-635
    • /
    • 2022
  • Purpose: Due to the change of demography, the ratio of senior drivers has increased and the transition to a super-aged society is expected to make more seniors drive in the future. Method: In this research, we analyzed medical characteristics of the driver's age-specific decline in body function and saw that both the function of the physical as well as mental capacities deteriorates as people age. Among them, various functions are precipitously weakened after reaching 70, implying that those over the age of 70 are classified as seniors in a medical sense. In this context, we also could identify that based on such age criteria, various safety policies for senior drivers should be developed and set up in Korea. Result: We could find a steep fall in the physical function of body after reaching 70 from the chronological change of cognitive function and judgment ability. In particular, it is revealed that the driving license institution and aptitude test for drivers over 70 should be thoroughly examined, as physical functions necessary for driving such as eyesight and hearing ability is not strong enough in many drivers over 70. Conclusion: Focusing on the physical capacity to drive, we tried to find the hazardous age bracket of senior drivers which might influence driving behaviors. Going forward, we expect this work would help to understand the policies for senior drivers and drivers' physical differences.

The Metabolism of Lipids in Adipose Pads and Superficial Pectoral Muscle of Chicks (닭의 지방조직(脂肪組織) 및 천흉근(淺胸筋)에서의 지질(脂質)의 대사(代謝))

  • Koh, Tae-Song
    • Korean Journal of Food Science and Technology
    • /
    • v.9 no.4
    • /
    • pp.264-270
    • /
    • 1977
  • In order to investigate the effect of dietary fatty acids on lipids metabolism in adipose pads and superficial pectoral muscle of chicks, the present, experiment was carried out using signle comb White Leghorn male chicks fed a fat-free diet and diets containing margaric, stearic or linoleic acids. Total lipids of tissues were extracted with a chlorofrom-methanol solution. The lipid components were fractionated by thin layer chromatography and the fatty acid distribution of lipid fractions was determined by gas liquid chromatography. The neck adipose pads contained 34-62% total lipids, in which triglycerides, were dominant, being 97-98%. Margaric, stearic and linoleic acids were distributed at a relatively high rate in the adipose tissue when the corresponding acids were fed, and margaric acid feeding lowered palmitoleic acid distribution and linoleic acid feeding elevated stearic acid distribution. The wet superficial pectoral muscle contained 1.3-1.7% total lipids, of which 77-79% was phospholipids and 11-13% was free cholesterol. When margaric acid was fed, margaric and heptadecenoic acids appeared in the muscle lipids. When linoleic acid was fed, this acid was significantly highly distributed in every muscle lipid fractions, whereas, when stearic acid fed no elevation of stearic acid distribution was observed. In the muscle phospholipids, oleic acid was significantly highly distributed in the stearic acid fed chicks, and the linoleic acid feeding signigicantly lowered the distribution value of palmitic and oleic acids, but elevated the distribution value of stearic acid. And the linoleic acid feeding lowered the distribution value of eicosatrienoic acid and elevated the distribution value of arachidonic acid.

  • PDF

Effects of Meju Powder Supplementation on Lipid Metabolism in Rats Fed Hypercholesterolemic Diet (고콜레스테롤 식이를 섭취한 흰쥐에 메주 분말 급여가 지질대사에 미치는 영향)

  • Kim, Jong-Dai;Lee, Young-Il;Kim, Bok-Rhan;Choi, Yong-Soon;Lee, Sang-Young
    • Journal of the Korean Society of Food Science and Nutrition
    • /
    • v.26 no.2
    • /
    • pp.314-318
    • /
    • 1997
  • This study was performed to examine the effects of Meju supplementation to high cholesterol diet on lipid metabolism in rats. Male Sprague-Dawley rats were divided into two groups(Steamed soybean, Meju) and were fed with 0.5% cholesterol diet. Serum and liver lipid profiles and fecal bile acids excretion were examined after four weeks of experimental diet. Food intake, weight gain and liver weight were not significantly different between the two groups. Total cholesterol concentrations in serum was significantly lower in Meju group compared to steamed soybean group(p<0.05). HDL-cholesterol, triglyceride, phospholipids and nonestrified fatty acid concentrations in serum were not significantly different between the two groups. Cholesterol, triglyceride, and phospholipids concentrations in liver were not significantly different between the two groups. Fecal bile acid excretion were markedly higher in Meju groups than the group fed steamed soybean(p<0.05). These results suggest that the cholesterol lowering effect by Meju supplementation might be resulted from the modulation of fecal bile acid excretion in rats.

  • PDF

Deletion of the VPS26b-VPS29-VPS35 Retromer Complex Results in Learning Disabilities and Neurodegeneration (VPS26b-VPS29-VPS35 리트로머 복합체 결여가 마우스 뇌조직에 미치는 영향)

  • Kim, Ekyune
    • Journal of Life Science
    • /
    • v.30 no.8
    • /
    • pp.708-712
    • /
    • 2020
  • Vacuolar protein sorting (VPS) 26b is a newly discovered member of the retromer complex; it is encoded by a single-copy gene located on mouse chromosome 9, and the complex has been reported as being composed of proteins VPS26, VPS29, and VPS35. We have previously shown that mice lacking VPS26b exhibited no significant body size or health issues. Although retromer components are widely expressed in mouse tissue, their roles have not yet been completely elucidated. The current study investigates whether the VPS26b-associated retromer complex can be used as a neurodegeneration model. Previously, we observed a significant reduction in VPS35 and VPS29 in the brain cells of in VPS26b-deficient mice as well as an absence of the VPS26b-VPS29-VPS35 retromer complex despite the normal presence of VPS26a-VPS29-VPS35. Recent studies have suggested that low levels of VPS35 can lead to Alzheimer's disease-like phenotypes including cognitive memory deficits. In this study, we successfully demonstrate an association between the absence of the VPS26b-VPS29-VPS35 retromer complex, reduced cell density in the CA3 region of the hippocampus, and learning disability in VPS26b knock-out mice. The results also indicate that the VPS26b-associated retromer complex affects neurodegenerative disorders and learning processes.

A Study on Hydraulic Experiment for Improvement of Dredging Efficiency (준설 효율 향상을 위한 수리실험 연구)

  • Chae, Dong-Seok;Park, Jae-Hyeon;Kim, Young-Do;Lee, Man-Soo
    • Proceedings of the Korea Water Resources Association Conference
    • /
    • 2007.05a
    • /
    • pp.1373-1377
    • /
    • 2007
  • 준설은 수중굴착, 운반(배송), 매립 기술로 구분되는데, 국내에서는 아직까지 각 기술을 통합한 체계적인 연구가 수행되지 못하고 있다. 준설분야는 토질, 수리 등의 토목 분야 기술뿐만 아니라 기계, 제어, 환경 등 여러 분야의 기술들이 매우 복잡하게 연계되어 있으며, 제한된 소수의 기술자들과 특수 대형 장비-준설선에 의해 수행되기 때문이다. 최근에는 장비의 대형화, 첨단화가 진행되면서 선진국과의 기술격차로 인해 국제 경쟁력이 약화되어 심각한 위기에 처해있는 현장기술 분야이다. 유럽의 델프트 공대, IHC, 준설협회(CEDA)는 세계 기술 개발을 주도하고 있으며, 미국에서는 육군공병단의 수로국에서 준설을 담당하고 있으며 DOER(Dredging Operation & Environmental Research) 기술 개발을 주도하는 등 선진국에서는 이미 여러 연구가 진행되었으며 준설기술이 정착되어있다. 본 연구에서는 현재 현대건설에서 보유중인 아산3호를 모델로 축소모형을 제작하여 실험하였다. 본 연구에서는 선행실험으로 성층형성 및 석션펌프 작동시 물입자의 운동방향을 PIV로 촬영한 결과에 커터헤드를 추가 장착 시행하여 이를 바탕으로 수치해석시 발생할 수 있는 오류를 수정 보완 할 것이다. 차후 실험에서는 준설토의 조건과 기계적 조건 및 환경적인 영향력을 고려한 여러 가지 방법으로 진행할 계획이며, 실험 조건에서는 각 매개변수를 달리하여 이를 토대로 데이터를 구성하고, 측정을 통해서 얻어지는 결과 값을 기초로 하여 준설시에 환경과 매개변수의 조건에 따른 준설량의 특성을 파악하고 효율을 향상시킬 수 있는 방향을 제시할 것이며, 이를 통해서 기본적인 메뉴얼을 구성할 계획이다. 수리실험의 결과값을 바탕으로 이를 현실무 작업에 적용할 경우 효율적인 준설작업을 수행할 수 있을 것으로 판단된다. HDL-콜레스테롤 함량은 유의차가 없었다. 간조직 중 총지질, 총콜레스테롤 및 중성 지방 함량은 HC군이 NC군에 비하여 유의하게 증가되었다. HC-LREL 군과 HC-LREH군은 HC군에 비하여 간조직 중 총지질 함량만이 유의하게 저하되었다. 이상의 결과 연근 에탄올 추출물은 in vitro에서 HMG-CoA reductase 활성을 농도 의존적으로 저하시켰으며, in vivo 에서는 고콜레스테롤 식이급여로 증가되어진 LDL-콜레스테롤 및 중성지질 함량을 감소시키고, 감소되어진 인지질 함량을 증가시킴으로써 고콜레스테롤 혈증 및 지방간의 예방과 치료에 효과가 있을 것으로 사료되나 연근의 어떠한 성분의 작용 기전에 의한 것인지에 대해서는 더욱 체계적인 연구가 요구된다.}nlein$ nephritis가 3례로 가장 많았다. 미세변화 신증후군 71명 중 비재발군이 16명으로 22.5%, 비빈발 재발군 49.3%, 빈발 재발군 18.3%, 스테로이드 의존군 9.9%를 보였다. 결론 : 대전시에서의 신증후군 환아의 발생빈도는 15세이하 소아 10만명당 약 5명으로 추정되었으며 10여 년전과 비교하여 큰 변화를 보이지는 않았다. 또한 저자들의 임상병리학적 연구결과가 다른 문헌에서 보고된 소아 신증후군의 연구결과와 큰 차이를 보이지 않음을 알 수 있었다. 자극에 차이가 있지 않나 추측되며 이에 관한 추후 연구가 요망된다. 총대장통과시간의 단축은 결장 분절 모두에서 줄어들어 나타났으나 좌측결장 통과시간의 감소 및 이로 인한 이 부위의 통과시간 비율의 저하가 가장 주요하였다. 이러한 결과는 차가운 생수 섭취가 주로 결장 근위부를 자극하는 효과를 발휘하는 것이 아닌가 해석된다. 이와 같은 연구결과를 통해 생다시마를 주원료로 개발된 생다시마차와 생다시마 음료가 만성 기능성 변비 증세를 개선하는 효

  • PDF

The Effects of Elderly Care Facility Social Workers' Work Environment and Personal Tendencies on Their Exhaustion (노인요양시설 사회복지사의 직무환경과 개인적 성향이 소진에 미치는 영향)

  • Hong, Suk ja;Seo, Sang Bum
    • Korean Journal of Social Welfare Studies
    • /
    • v.42 no.4
    • /
    • pp.187-216
    • /
    • 2011
  • This study examined the effects of elderly care facility social workers' work environment (role conflict, role ambiguity, role overload, and adequacy of the reward system) and personal tendency (emotional empathy, cognitive empathy, external attribution, and internal attribution) on their burnout (emotional burnout, low personal achievement, and depersonalization about clients) and suggested strategies for preventing burnout in social workers at elderly care facilities. For this purpose, we conducted a questionnaire survey of social workers working at institutions designated as elderly long-term care facilities and collected a total of 312 questionnaires. According to the results of analyzing the data using a structural equation model, among the sub-factors of work environment, role ambiguity had a significant positive effect on low personal achievement and depersonalization about clients, role conflict on emotional burnout, and role overload on depersonalization about clients. Among the sub-factors of personal tendency, cognitive empathy and internal attribution had a significant negative effect on low personal achievement, and external attribution had a significant positive effect on emotional burnout and depersonalization about clients. This study is meaningful in that it illuminated social workers' burnout not only from the aspect of work environment but also from that of personal tendency.

The Impact of Social Exclusion on Consumer Response : The Moderating Effect of Embodied Cognition (사회적 배제가 소비자 반응에 미치는 효과 : 체화된 인지의 조절효과를 중심으로)

  • Son, Jung-sik;Lee, Byung-kwan
    • Science of Emotion and Sensibility
    • /
    • v.18 no.3
    • /
    • pp.107-114
    • /
    • 2015
  • In today's society, the experience of social exclusion caused by being rejected or ignored, leads to negative social consequences, such as aggressive behavior, self-defeating thoughts, and diminished intelligence. This study is performed to examine 1) how two types of social exclusion, rejection and ignorance, affect conspicuous consumption and prosocial behavior and 2) how embodied cognition formed with a firmed muscle moderates their causal relationships. For this purpose, half of the participants in ignorance and rejection conditions were asked to grip their hands to form a firmed muscle (firmed muscle group) while the other half (control group) were not. After the manipulation of embodied cognition, their conspicuous consumption and intention of prosocial behavior were measured. Results show that, in ignorance condition, the firmed muscle group exhibited lower conspicuous consumption and higher intention of prosocial behavior than the control group while, in rejection condition, there were no differences in conspicuous consumption and intention of social behavior between firmed muscle and control groups. Findings indicate that, in the case of social exclusion caused by ignorance, firmed muscle improves self-efficacy, which may increase prosocial behavior.

Effect of Complex Exercise Programs on Physical Fitness, Activities of Daily Living and Cognitive Status in Frail Elderly (허약노인의 복합운동프로그램 참여가 체력, 일상생활수행능력 및 인지상태에 미치는 영향)

  • Park, Hyunyoung;Shin, Sohee
    • 한국노년학
    • /
    • v.40 no.3
    • /
    • pp.429-442
    • /
    • 2020
  • The purpose of this research was to examine changes in the physical fitness, activities of daily living performance, and cognitive status of the frail elderly by combined exercise programs. The combined exercise program consisted of an aerobic exercise for the elderly and a four-color ladder exercise for improving of cognitive ability and physical fitness. Twenty-one frail elderly participated in this study, they were divided into 12 exercise groups and nine control groups. The exercise group conducted the combined exercise program of 60 minutes, twice a week, for10 weeks, while the control group maintained their normal lives. Strength, flexibility, agility, coordination, ADL and MMSE-K were measured. Exercise group showed significant improvement in grip strength compared to control group. In addition, ADL showed significant improvement only in the exercise group. The results of this study showed that participation in the combined exercise program of the el derl y was effective in improving the grip strength, and in preventing various physical functions and cognitive conditions decline.