• Title/Summary/Keyword: 이차분석

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Functional Analysis of the Residue 789 in Escherichia coli 16S rRNA and Development of a Method to Select Second-site Revertants (Escherichia coli 16S rRNA의 789 염기의 기능분석 및 이차복귀돌연변이체 발췌를 위한 방법 개발)

  • Kim Jong-Myung;Go Ha-Young;Song Woo-Seok;Ryou Sang-Mi;Lee Kang-Seok
    • Korean Journal of Microbiology
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    • v.42 no.2
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    • pp.156-159
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    • 2006
  • A base substitution was introduced at the position 789 in Escherichia coli 16S rRNA, which was previously identified as an invariant residue for ribosome function and the ability of the mutant ribosomes to translate chloramphenicol acetyltransfernse mRNA was measured by determining the degree of resistance to chloramphenicol of cells expressing these mutant ribosomes. As expected, mutant ribosomes containing a base sub-stitution at the position 789 showed significantly reduced protein-synthesis ability and to identify a functional role played by this residue in protein synthesis, we developed an efficient genetic method to select second-site revertants in 16S rRNA that restore protein-synthesis function to these mutant ribosomes.

Physical Activity and Anxiety of Adolescents during the COVID-19 Pandemic in South Korea (코로나19 팬데믹 시대에 한국 청소년의 신체활동과 불안)

  • Choi, Hye-Seon;Shin, Miah
    • Journal of Industrial Convergence
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    • v.20 no.10
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    • pp.95-101
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    • 2022
  • The purpose of this study is to determine the association between physical activity and anxiety levels in Korean adolescents after COVID-19 Pandemic. This study performed a secondary analysis of the 16th Korea Youth Risk Behavior Survey 2020. Complex-sample descriptive statistics and the chi-square test were used for data analysis in SPSS 27. As a result, 60.9% of adolescents engaged in physical activity for more than 60 minutes a day and 39.1% of those did not. The level of anxiety among adolescents was found to be mild anxiety at 22.2%, moderate anxiety at 7.6%, and severe anxiety at 3.6%. A significant association was found between physical activity and anxiety levels (p <.001). Therefore, there should be a plan to increase physical activity in the national policy for the promotion of youth mental health.

Flow Characteristics through the Singok Submerged Weir in Downstream of the Han River (한강하류 신곡수중보의 흐름특성)

  • Kim, Su Jin
    • Proceedings of the Korea Water Resources Association Conference
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    • 2020.06a
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    • pp.20-20
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    • 2020
  • 신곡수중보는 한강종합개발사업(1982년~1986년) 중 하도정비로 인하여 상시 수위가 저하됨으로써 조수의 과도한 역류 등으로 발생하는 이수상의 문제점을 해결하고 상류에 설치된 잠실수중 보 사이의 수위유지 및 하천 공간 이용의 극대화, 연안 농경지의 용수공급 및 하천환경 보전을 목적으로 건설되어, 「잠실 및 신곡수중보 관리규정(1986)」 및 「신곡수중보 운영 매뉴얼」에 의해 관리·운영되고 있다. 신곡수중보는 준공된 이래로 한강하류의 흐름 해석에 있어 중요한 기준과 경계로서 이와 관련한 다양한 연구가 진행되었다. 신곡수중보로 인한 흐름의 변화가 하상과 생태에 미치는 영향에 관한 연구와 하구역에서의 조위 및 흐름특성과 밀도류의 거동에 관한 1, 2차원 수치해석연구가 활발히 진행되었다. 본 연구에서는 그동안 1, 2차원 수치해석연구로 한정되었던 신곡수중보 흐름특성에 관련하여 실제 수문 운영 방식을 반영한 3차원 수치해석을 수행하여 구조물의 상·하류에서 발생하는 와류 및 이차류와 같은 3차원적 흐름 구조와 이에 따른 지형의 침식·퇴적 및 구조물에 미치는 영향 등을 구체적으로 분석하였다. 우선, 신곡수중보 운영 매뉴얼과 실제 가동보 운영시스템을 비교하여 수문개방 시기, 유량 기준의 수문 운영 방법, 수위 변화에 따른 수문 운영 방법, 수문개방 순서를 분석하고 신곡수중보 주변 흐름에 대한 3차원 수치해석모형 구축을 위한 경계조건을 산정하였다. 수치해석에는 상용프로그램인 FLOW-3D를 사용하였으며, 경계처리기법 및 난류해석을 위해 FAVOR 기법과 RNG k-ε 모델을 적용하였다. 수문 동시개방 개수, 수문 개방 위치 및 순서, 개방 높이에 대한 조건을 변화시켜 구성한 시나리오에 대해 수치해석 후, 유속, 난류에너지, 이차류 등의 흐름특성을 분석하고 상·하류 수위차에 따른 방류량을 산정하여 시설물의 관리안을 도출하고 운영 매뉴얼의 개정안을 제시하였다.

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Effect of Plant Growth Regulator Treatment on Isoflavones in Soybean (생장조정제 처리에 따른 콩 이소플라본 영향 분석)

  • Jinhee Seo;Seoyeon Hong;Jaesung Park;Okjae Won;Wonyoung Han
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2023.04a
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    • pp.64-64
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    • 2023
  • 콩은 중요한 식량 작물로 단백질, 기름 및 이차대사산물인 이소플라본을 다량으로 함유하고 있다. 이소플라본은 폴리페놀의 일종으로 일부 암을 예방하며 심혈관 질환을 완화하는 데에도 도움을 준다고 알려져 있다. 콩에 인위적으로 식물호르몬인 ABA를 처리할 때 이차대사산물인 kaempferol의 함량이 증가한다고 보고 되었다. 따라서 이 연구는 식물 생장조정제 처리가 콩잎의 이소플라본 함량에 미치는 영향을 알아보기 위해 수행되었다. 연구는 밀양 남부작물부 유리온실에서 수행되었으며, 콩(품종:선풍)은 와그너포트 1/2000에 1주 2본 파종하여 재배하였다. Ethephone(500, 1000, 2000 ppm)과 ABA(100, 200, 400 ppm)를 사용하였으며 각각 R2, R5, R7기에 처리하였다. 처리 후 잎을 5일 간격으로 3회 채취하여 이소플라본 6종과 쿠메스트롤의 함량을 분석하였다. 초고성능 액체 크로마토그래피(Acquity UPLC H-Class system, Waters)를 사용하여 분석하였다. 이소플라본 함량은 R5 단계에서 전반적으로 높게 나타났으며, R2 및 R7 단계에서는 무처리와 유사한 수준을 보였다. ABA를 처리하였을 때 생장조정제 간의 차이가 에테폰보다 더 큰 것으로 나타났다. 쿠메스트롤 함량은 처리시간에 따라 R7, R5, R2 순으로 높은 것으로 확인되었으며, 처리시간이 지날수록 함량이 증가함을 알 수 있었다. 생장조정제 처리에 쿠메스트롤 함량은 ABA보다 에세폰 처리 시 더 높은 경향을 보였다.

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The Relationship Between Self-Esteem, Disability Acceptance, and Depression in Adults with Physical Disabilities (성인 지체장애인의 자아존중감, 장애 수용 및 우울간의 관련성)

  • Moonkyoung Park;Younghee Jeong
    • Journal of Advanced Technology Convergence
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    • v.3 no.3
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    • pp.1-7
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    • 2024
  • This study aimed to identify the factors influencing depression in adults with physical disabilities through a secondary data analysis. The study analyzed data from 867 adults who reported having physical disabilities in the 2018 Panel Survey on Disability conducted by the Korea Disabled People's Development Institute. Descriptive statistics and logistic regression analysis were performed using SPSS 29.0 with a complex sample design. The cause of disability was acquired in 98.1% of the participants, and 53.8% of them reported experiencing depression. Self-esteem (OR=0.18, 95% CI=0.08-0.39) and disability acceptance (OR=0.17, 95% CI=0.08-0.38) were significant factors influencing depression in adults with physical disabilities. These findings suggest that interventions aimed at promoting disability acceptance and enhancing self-esteem may effectively alleviate depression in this population.

Proposing Shape Alignment for an Improved Active Shape Model (ASM의 성능향상을 위한 형태 정렬 방식 제안)

  • Hahn, Hee-Il
    • Journal of Korea Multimedia Society
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    • v.15 no.1
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    • pp.63-70
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    • 2012
  • In this paper an extension to an original active shape model(ASM) for facial feature extraction is presented. The original ASM suffers from poor shape alignment by aligning the shape model to a new instant of the object in a given image using a simple similarity transformation. It exploits only informations such as scale, rotation and shift in horizontal and vertical directions, which does not cope effectively with the complex pose variation. To solve the problem, new shape alignment with 6 degrees of freedom is derived, which corresponds to an affine transformation. Another extension is to speed up the calculation of the Mahalanobis distance for 2-D profiles by trimming the profile covariance matrices. Extensive experiment is conducted with several images of varying poses to check the performance of the proposed method to segment the human faces.

SHRIMP V-Pb Zircon Age of a Felsic Meta-tuff in the Ogcheon Metamorphic Belt, Korea: Neoproterozoic (ca. 750 Ma) Volcanism (옥천변성대 규장질 변성응회암의 SHRIMP U-Pb 저어콘 연대: 신원생대(약 7.5억년전) 화산활동)

  • 조문섭;김태훈;김현철
    • The Journal of the Petrological Society of Korea
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    • v.13 no.3
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    • pp.119-125
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    • 2004
  • Using a SHRIMP ion microprobe, we have dated zircon grains of a felsic meta-tuff from the so-cal1ed Munjuri Formation, Ogcheon metamorphic belt. The weighted mean $^{206}$ Pb/$^{238}$ U zircon ages obtained from 13 spot analyses of 10 grains provide an essentially concordant age of 747${\pm}$7Ma. This result corroborates the conventional U-Pb zircon age (756${\pm}$1Ma; Lee et al., 1998) for the Neoproterozoic bimodal volcanism in the Ogcheon belt. Thus, proto-basins associated with intracontinental, high-volcanicity rift in the Ogcheon belt are most likely to have formed at ca. 750 Ma.

Design of Open Vector Graphics Accelerator for Mobile Vector Graphics (모바일 벡터 그래픽을 위한 OpenVG 가속기 설계)

  • Kim, Young-Ouk;Roh, Young-Sup
    • Journal of Korea Multimedia Society
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    • v.11 no.10
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    • pp.1460-1470
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    • 2008
  • As the performance of recent mobile systems increases, a vector graphic has been implemented to represent various types of dynamic menus, mails, and two-dimensional maps. This paper proposes a hardware accelerator for open vector graphics (OpenVG), which is widely used for two-dimensional vector graphics. We analyze the specifications of an OpenVG and divide the OpenVG into several functions suitable for hardware implementation. The proposed hardware accelerator is implemented on a field programmable gate array (FPGA) board using hardware description language (HDL) and is about four times faster than an Alex processor.

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A Path Analysis on Factors Influencing Second Primary Cancer Screening Practices in Stomach, Colon, and Breast Cancer Survivors (암 생존자의 이차암 검진 영향요인에 대한 경로분석: 위암, 대장암, 유방암 생존자 대상으로)

  • Yang, Young Hee
    • Journal of Korean Academy of Nursing
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    • v.44 no.2
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    • pp.139-148
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    • 2014
  • Purpose: This study was conducted to identify the factors influencing second primary cancer (SPC) screening practice by examining the relationships of physical symptoms, knowledge and attitudes regarding SPC screening, perceived risk, primary cancer type, and demographic factors of cancer survivors. Methods: Participants were 308 survivors of stomach, colon, or breast cancer recruited from 2 university hospitals in Korea. Data were collected using a questionnaire and analyzed using IBM SPSS 21.0 and AMOS 18.0. Results: The proportion of participants taking all cancer screenings according to national guidelines was 40%. They had moderate knowledge and a relatively positive attitude regarding SPC screening and high cancer risk perception. The participants had taken fewer SPC screenings after than before cancer diagnosis. The factors influencing cancer risk perception were age, physical symptoms, knowledge regarding SPC and primary cancer type (stomach). The factors influencing SPC screening practice were age, gender, economic status, knowledge regarding SPC screening, and primary cancer types (colon). Conclusion: It is important for clinical professionals to recognize that survivors of cancer are susceptible to another cancer. Education on SPC screening for these survivors should focus on communicating with and encouraging them to have regular cancer screenings.

Analysis of Factors Influencing Secondary Traumatic Stress, Burnout, and Physical Symptoms in Firefighters (소방대원의 이차 외상성 스트레스, 소진 및 신체적 증상의 영향요인 분석)

  • Oh Jin-Hwan;Lim Nan-Young
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.13 no.1
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    • pp.96-106
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    • 2006
  • Purpose: This study was dont: to evaluate the factors that influence secondary traumatic stress, burnout, and physical symptoms experienced by firefighters. In addition, a hypothetical model was developed. Method: The data were collected using self-reported questionnaires from 410 field service firefighters. Data analysis was done with the SPSSWIN 10.0 program for descriptive statistics and Windows LISREL program to determine the causal relationship between the measurement variables. Results: The hypothetical model which was developed fits well with actual data(${\chi}^2$=3.16, p=0.99, GFI=1.00, AGFI=0.99, NFI=0.99, and NNFI=1.06). The variable, personality type, social support, and impact mobilization frequency had a significant effect and accounted for 7% of the secondary traumatic stress in firefighters. The variables, career, social support, and secondary traumatic stress had a significant effect and accounted for 24% of the burnout in firefighters. Social support, impact mobilization frequency, and secondary traumatic stress were important variables and accounted for 31% of the physical symptoms in firefighters. Conclusion: It is necessary for firefighters to manage themselves according to their personality types. Strategies that can increase the firefighters' social support and decrease their perceived secondary traumatic stress also need to be developed to minimize or prevent a negative effect on their health.

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