• Title/Summary/Keyword: 이재근

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Development of Trans-Admittance Scanner (TAS) for Breast Cancer Detection (유방암 검출을 위한 생계 어드미턴스 스캐너의 개발)

  • 이정환;오동인;이재상;우응제;서진근;권오인
    • Journal of Biomedical Engineering Research
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    • v.25 no.5
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    • pp.335-342
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    • 2004
  • This paper describes a trans-admittance scanner for breast cancer detection. A FPGA-based sinusoidal waveform generator produces a constant voltage. The voltage is applied between a hand-held electrode and a scan probe placed on the breast. The scan probe contains an 8x8 array of electrodes that are kept at the ground potential. Multi-channel precision digital ammeters using the phase-sensitive demodulation technique were developed to measure the exit current from each electrode in the array. Different regions of the breast are scanned by moving the probe on the breast. We could get trans-admittance images of resistor and saline phantoms with an anomaly inside. The images provided the information on the depth and location of the anomaly. In future studies, we need to improve the accuracy through a better calibration method. We plan to test the scanner's ability to detect a cancer lesion inside the human breast.

An Efficient Correction Process of CT-Simulator Couch with Current Diagnostic CT Scanners (진단용 CT-모의치료기 테이블의 효율적인 교정 방법)

  • Goo, Eun-Hoe;Lee, Jae-Seung;Cho, Jung-Keun;Moon, Seong-Kwon
    • The Journal of the Korea Contents Association
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    • v.9 no.11
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    • pp.254-261
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    • 2009
  • This study suggested that the table of CT-simulator and the laser alignment system using diagnostic CT scanner have an efficient method for improvement in alignment between the planned target center of traverse image with CT scanner. It was conducted on the daily QA when presented in the AAPM TG66 with correcting the laser alignment system using geometric trigonometric functions and investigated the effectiveness of correction methods as compared with those before and after correction. Before correction error was 3.82mm between the planned target center of image, the table longitudinal axis was twisted with 0.436o. The laser alignment system using geometric trigonometric functions in after correction was satisfied with tolerance limits of ${\pm}2mm$ when occurred about 0.7mm in errors between the planned target center. The table correction to satisfy the geometric accuracy is very inefficient over against the time and economic loss as well as technical limits in the case of application as only radiation therapy associated with CT-simulator with diagnostic CT scanner in use. But, the method which corrects the laser alignment system is economic and relatively simple with possibility of getting well geometric accuracy and we suppose that it is efficient method for applying in the clinic.

Construction of A Bacteriocidal Yeast Producing Bacteriocin OR-7 (박테리오신 OR-7을 생산하는 항균 효모의 제작)

  • Lee, Ok-Hee;Jang, Min-Kyung;Lee, Dong-Geun;Lee, Jae-Hwa;Ha, Jong-Myung;Ha, Bae-Jin;Ahn, Ik-Yong;Cho, Dong-In;Lee, Sang-Hyeon
    • Microbiology and Biotechnology Letters
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    • v.36 no.2
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    • pp.101-105
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    • 2008
  • In order to obtain yeast cells producing a bacteriocin OR-7, the 180 bp polynucleotide corresponding to the OR-7 gene including codons for start and stop was chemically synthesized and cloned into pAUR123, an yeast expression vector. Transformed yeast cells exhibited growth inhibition of Bacillus subtilis, Campylobacter jeuni, Escherichia coli and Pseudomonas aeruginosa. This result indicates that yeast cells producing OR-7 possess bacteriocidal properties against both Gram positive B. subtilis and Gram negative C. jejuni, E. coli and P. aeruginosa cells. The recombinant yeast strain constructed in this study can be applied in the food preservative or animal feed.

Comparison of compost product quality with nature soil standard (국내생산퇴비의 부숙토 기준에 대한 적합성 검토)

  • Choi, H.G.;Lee, J.A.;Kim, K.Y.;Lee, K.C.;Lee, J.G.;Park, K.H.;Park, J.S.;Phae, C.G.
    • Journal of the Korea Organic Resources Recycling Association
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    • v.9 no.2
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    • pp.77-86
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    • 2001
  • As construction and expansion of wastewater treatment works is continuing, generation of sludge is increasing. Bur most sludge is not used appropriately but disposed by landfill dumping to sea. Furthermore direct landfilling of sludge cake containing moisture content over 75% has been legally prohibited since 2001 that's enforcement will be more strict in 2003. Such a situation means nowadays recycling of organic waste such as sludge and food waste is necessary. Composting is one of recycling methods commonly and used as an effective means of stabilizing organic waste and then compost can be used as fertilizer. However fertilizer law management which include standard of compost products and other fertilizers applied all sludge products indiscriminiately and was not flexible. So MOE has graded organic composts according to land applications to improve recycle of organic wastes. The classified organic compost which contains low contaminants has been possible to use as various purpose. This study enalyzed 30 samples which were raw materials for compost and compost products management well and to estimate the quality of compost products. Heavy metals were measured in Raw materials and OM/N, NaCl and VS were tested in compost products as well as heavy metals. As a result, approximate 10% of raw materials was not suitable to the grade A and 6.7% over the grade B of the regulation on raw materials for compost. In the case of 30 produced compost propducts approximate, 57% of composts was not compatible with the grade A and B of the regulation on composting product. The qualities of compost products were worse than raw materials, because the compost products have more regulation item raw materials have.

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Microanatomy of Philtral ridge (인중의 미세해부학적 고찰)

  • Lee, Jong-Ho;Jeon, Se-Il;Myung, Hoon;Lim, Koo-Young;Seo, Byung-Moo;Choi, Jin-Young;Choung, Pill-Hoon;Kim, Myung-Jin;Hong, Sam-Pyo;Lee, Jae-Il;Lim, Chang-Yun
    • Korean Journal of Cleft Lip And Palate
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    • v.3 no.1
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    • pp.11-16
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    • 2000
  • Many efforts are made to achieve satisfactory cosmetic and functional result in the repair of cleft lip. However, repair may be complicated in many cases by distortion of the vermilion border, obliteration of the normal contour of the philtrum, and eclabium in spite of many methods used in these days. To achieve better results in cleft lip repair, thorough understandings of the relationship between the surface morphology of the upper and lower lip and the underlying musculature is necessary but reports about this topic is rare. So, our studies were performed on the full-thickness upper lips containing both philtral ridge up to columelar base and lower lip, 4 post-mortem specimens of 2 females and 2 males aged from 16 to 42, using serial histological sections taken in the transverse and vertical planes under light microscopy. Thorough understanding of the anatomical relationships is established and on the basis of our findings, we can postulate some criteria to create a normal and natural philtrum in a patient with a cleft lip, it would be necessary to restore the normal deep muscle attachments and superficial dermal attachments of the orbicularis muscle, to close the lip without tension, to restore thickness of the philtral ridge, and to minimise nonelastic scar tissue.

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The Role of Bone Scans in Routine Preoperative Evaluations of Non-Small Cell Lung Cancer Patients. (비소세포 폐암의 병기에 있어 통상적인 골 스캔의 역할)

  • 김영태;홍장미;이재익;이정상;성숙환;김주현
    • Journal of Chest Surgery
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    • v.35 no.9
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    • pp.659-663
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    • 2002
  • The objective of this study was to assess the usefulness of bone scans in routine preoperative examinations of patients with newly diagnosed non-small cell lung carcinoma. Material and Method: We reviewed the medical records of 258 patients who were newly diagnosed with non-small cell lung cancer in our hospital between January 2000 and December 2000. More than half of the patients (132) were deemed to be inoperable due to their advanced stage based on the CT scans. The remaining 126 patients were considered potentially operable. For these patients, clinical evaluation including the presence of bone pain, serum alkaline phosphatase, and calcium levels was used as clinical predictors of bone metastasis. All patients received bone scans. Bone X-rays, MRI or bone biopsy were performed to confirm the presence of bone metastasis. The usefulness of the bone scan was evaluated by comparing its power of predicting bone metastasis to that of the clinical information. Result: In all patients, the positive and negative predictive values of bone scans for the bone metastasis were 44%, and 99%, respectively. Those of the clinical information were 38% , and 94%. However, in potentially operable patients, the negative predictive value of the clinical information was as high as 99%. Conclusion: If newly diagnosed non-small cell lung cancer patients are presented as potentially operable on the basis of CT scan with no clinical evidence of distant metastases, curative resection could be considered without performing routine bone scans because of the low probability of bone metastasis. However, if there are positive clinical findings, further evaluations, including bone scan should be followed as metastasis will be documented in more than 30% of patients.

Discussion of Neurologic Factor Influencing on Chewing Ability of Implant (임플란트 저작능에 영향을 주는 신경학적 원인에 대한 고찰)

  • Kim, Tae-Seon;Yoon, Jun-Ho;Kim, Sung-Hoi;Kim, Jee-Hwan;Shim, June-Sung;Lee, Jae-Hoon;Moon, Hong-Suk;Park, Young-Bum
    • Journal of Dental Rehabilitation and Applied Science
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    • v.28 no.3
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    • pp.269-276
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    • 2012
  • Many researches have been published about the numerous factors related to the chewing ability of implant prosthesis. Most respective studies have concluded that the chewing ability of implant prosthesis is mostly fine compared to other type of prosthesis. However, some patients are not satisfied with their chewing ability of implant prosthesis. Therefore the neurologic factor, one of the factors related to dissatisfaction of chewing ability was reviewed in this study to understand the mechanism of action of mastication. Data was searched using the keywords; 'implant chewing ability, masticatory ability' in Pubmed database and reviewed. Definitions of chewing ability, factors of chewing ability are reviewed and the neurologic factor, one of the factors influencing on chewing ability, is reviewed. Mechanoreceptor of Periodontal ligament(PDL) is providing the mastication information to brainstem. Due to the absence of mechanoreceptions of PDL in implant, masticatory ability is decreased especially when chewing hard food. Masticatory muscles and mechanoreceptor in TMD may compensate the lack of mechanoreceptor of PDL in implants. Furthermore sensitivity of nerve fiber around peri-implant tissues may support the mechanoreception and sensory reaction in the implant mastication. However, further studies should be conducted to prove the relationships between neurologic factors and mastication.

Unplanned Excision of Soft Tissue Sarcoma: Patient Profile and Treatment Outcomes (연부 조직 육종에 대한 무계획적 절제술: 환자의 임상적 특징 및 치료 결과)

  • Lee, Jae Hoo;Cho, Yong Jin;Kim, Seung Hyun;Shin, Kyoo Ho
    • The Journal of the Korean bone and joint tumor society
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    • v.18 no.2
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    • pp.72-77
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    • 2012
  • Purpose: Unplanned excision of a soft tissue sarcoma is defined as the operation performed for gross removal of a soft tissue sarcoma without regard for preoperative imaging or the necessity to removal a margin of normal tissue covering the cancer. We report our experience of treating primary soft tissue sarcoma after an unplanned excision. Materials and Methods: We retrospectively reviewed 31 patients referred to our hospital after unplanned excision at other hospitals for treatment of a STS. The clinical information was reviewed with a focus on the patient's age, gender, tumor location, tumor size, tumor depth, presumptive diagnoses at the previous surgery, refer hospital, definitive diagnosis, interval between the initial and additional surgery and local recurrence. Results: There were 19 males and 12 females with a median age of 48 years (range, 17-75 years) at the time of referral. Seventeen patients (54.8%) had tumors in their lower limb, 6 (19.4%) had tumors in their upper limb, and 8 (25.8%) had tumors in their trunk. Tumor depth could be determined for 8 patients (25.8%), with superficial and 22 deep tumors (71%). The medial interval between unplanned excision to re-excision ranged from 2 weeks to 1 year (median, 5 weeks). Local recurrence was detected in 2 patients. All patients were alive without metastasis at last follow up. Conclusion: Even in upper class general hospital, many unplanned excision had been performed, which is considered to be avoided. When the relatively huge mass located in deeper layer it requires enough preoperative imaging studies and biopsy.

Response of Ozone Sensitivity in Open-Pollinated Families of Pinus densiflora Seedlings (소나무 풍매차대묘(風媒次代苗)의 가계간(家系間) 오존에 대한 민감성(敏感性) 반응(反應))

  • Lee, Jae-Cheon;Oh, Chang-Young;Han, Sim-Hee;Kim, Jang-Su
    • Journal of Korean Society of Forest Science
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    • v.94 no.3 s.160
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    • pp.191-196
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    • 2005
  • This studies were conducted to compare ozone sensitivity among half-sib families of Japanese red pine (Pinus densiflora S. et Z.). 90 families were exposed in walk-in type chambers to charcoal-filtered air and 100 ppb ozone for 8 hours daily, 5 consecutive months. We surveyed the foliar injury, Relative DRC (diameter at root collar) growth and relative dry weight after fumigation. After 5 months of exposure, foliar injury ranged from 1.9% at tolerant group to 15.2% at sensitive group. Relative DRC growth rates showed increased 12% at tolerant group, but reduced 23% at sensitive group. Total dry weight increased 17% at tolerant group, otherwise reduced by 33% at sensitive group, relative to the control. The root biomass showed more sensitive than the other part biomass. On the basis of the results of these screening studies, families Kangwon 04, 16, 26, 27 and 73 were determined to be tolerant; Kangwon 40, 52, 83, Gyeonggi 01 and Gyeongbuk 20 to be sensitive to ozone. Considerable genetic variation in ozone responses occurred, as shown by differences in sensitivities among families and among groups. These results indicate that tolerant groups of P. densiflora exhibited a high degree of resistance to ozone pollution injury.

The Effects and Adverse Events of Gamiwolbigachultang on the Changes of Body Composition and Musculoskeletal Pain in 28 Overweight Patients: A Retrospective Observational Study (근골격계 통증을 호소하는 과체중 환자 28례에 대한 가미월비가출탕의 효과 및 부작용에 관한 임상적 관찰)

  • Kwak, Hyun-Young;Kim, Ji-Hye;Seon, Jong-In;Lim, Sung-Keun;Kwon, You-Jung;Kim, Dong-Hyuk;Lee, Ung-In;Kang, Jung-Won;Lee, Jae-Dong;Choi, Do-Young
    • Journal of Acupuncture Research
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    • v.28 no.5
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    • pp.103-110
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    • 2011
  • Objectives : The purpose of this study is to investigate the effect and adverse events of Gamiwolbigachul-tang on the changes of body composition and musculoskeletal pain in overweight patients. Methods : A total of 28 patients with overweight patients who were complaining musculoskeletal pain were treated with Gamiwolbigachul-tang more than 4 weeks between January 2011 and August 2011 in Kyung Hee University Oriental Medical Hospital were observed. We have evaluated the efficacy of treatments by measuring the changes of body composition (Body weight, Body mass index, Skeletal muscle mass, Body fat mass and Waist hip ratio) and musculoskeletal pain. The 28 patients were analyzed according to the distribution of sex, age, body compostition and musculoskeletal pain. Results : 1. There were statistically significant changes on Body weight and BMI in 28 patients after 4 weeks of treatment. 2. Gamiwolbigachul-tang had effect on reducing Body fat mass rather than Fat free mass. 3. There were statistically significant changes on musculoskeletal pains such as lower back pain, knee pain after treatment. 4. There were few side effects except those common complications such as insomnia(3 patients), palpitation(2 patients) and indigestion(1 patients), which did not have effects on everyday living. Conclusions : These results suggest that Gamiwolbigachul-tang will be beneficial for overweight patients with musculoskeletal pain, having both effectiveness and safety.