To investigate the work-relatedness of carpal tunnel syndrome of some workers at packing department in a rayon manufacturing company, reseracher studied the symptoms and physical sign related to carpal tunnel syndrome of the workers at packing, ysrning, and washing department. The results are as follows: 1. By the results of ergonomic study, the packing work had the considerable probability to develop the carpal tunnel syndrome. 2. The prevalences of symptoms, physical sign and case by definition were higher in woman workers than in man workers. 3. In female workers, the age-agjusted prevalence rates of symptoms were 11.6/1, 000 in workers at washing department, 111.6/1, 000 in workers at packing department, and 70.1/1, 000 in workers at yarning department. In male workers, the age- adjusted rates of symptoms were 92.1/1, 000 in workers at washing department, 210.1/1, 000 in workers at packing and delivery department, and 0.0/1, 000 in workers at yarning department. 4. In female workers, the age-adjusted prevalence rates of physical signs were 119.5/1, 000 in workers at washing department, 104.4/1, 000 in workers at packing department, and 84.5 in workers at yarning department. In male workers, the age-adjusted rates of physical signs were 65.7/1, 000 in workers at washing department, 59.0/1, 000 in workers at packing and delivery department, and 176.9/1, 000 in workers at yarning department. 5. In female workers, the age- adjusted prevelence rates of carpal tunnel cases by case definition were 123.1/1, 000 in workers at washing department, 1117.2/1, 000 in workers at packing department, and 60.2/1, 000 in workers at yarning department. In male workers, the age-adjusted of cases were 355.9/1, 000 in workers at packing and delivery department, and 0.0/1, 000 in workers at other two departments. 6. The most of female workdrs at washing departmentn had the work history at packing department. 7. We concluded the carpal tunnel syndrome of female workers at packing department were work related.