• Title/Summary/Keyword: 이두식

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Distribution of Fluoroquinolones in the Carp (Cyprinus carpio) and Eel (Anguilla japonica) following their Oral Administration (양식 잉어 및 뱀장어에 경구투 fluoroquinolone계 항생제의 체내 잔류량의 변화)

  • Jo, Mi-Ra;Park, Kun-Ba-Wui;Lee, Hee-Jung;Kim, Ji-Hoe;Lee, Tae-Seek;Jung, Sung-Hee;Lee, Doo-Seog;Yoon, Ho-Dong;Kim, Poong-Ho
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.43 no.6
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    • pp.623-628
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    • 2010
  • The distribution of fluoroquinolones was investigated in the carp (Cyprinus carpio) and eel (Anguilla japonica) after an oral dose of 20 mg/kg body weight/day for 35 days. Blood samples were collected at 5 and 10 hours and 1, 2, 3, 5, 7, 9, 13, 20, 30, and 35 days after treatment. The fluoroquinolone concentrations were determined high- performance liquid chromatography with an ultraviolet detector. The recovery rates of fluoroquinolones in the fish samples ranged from 91.4-96.6, 91.2-96.5, and 90.4-98.6% for concentrations of 0.1, 0.5, and $1.0\;{\mu}g/g$, respectively. In the blood of carp, ciprofloxacin, enrofloxacin, norfloxacin, and sarafloxacin reached maximums level of 11.03, 9.37, 9.10, and $9.81\;{\mu}g/g$ 10 hours, 1 day, 10 hours, and 10 hours after treatment, respectively. In the eel blood, these reached maximum levels of 12.65, 11.18, 11.91, and $8.74\;{\mu}g/g$ all at 10 hours. Carp sample concentrations of ciprofloxacin, enrofloxacin, norfloxacin, and sarafloxacin were not measurable 20, 30, 20, and 20 days after treatment, respectively, in all experiments (

Characteristic Analysis of Reduced Motion due to the Shape of Floating Structure (부유구조체 형상에 따른 동요감소 특성분석)

  • Lee, Du Ho;Jeong, Youn Ju;You, Young Jun;Park, Min Su
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.25 no.6
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    • pp.357-364
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    • 2013
  • In previous study, the hybrid floating structure composed of a pontoon and a semi-submersible was suggested to reduce the motions of floating structure. It was reported that the suggested hybrid floating structure could reduce the motions. However, the hybrid floating structure could not support enough buoyancy. In this study, the combination floating structure is newly suggested to resolve the problem. In order to adopt the shape of floating structures reducing the motions, the hydrodynamic analysis of various floating structures such as the pontoon, the hybrid and the combination of floating structure is carried out through hydrodynamic analysis program ANSYS AQWA. It is found that the combination floating structure is remarkably effective to reduce the motions compared to the other cases. Thus, the suggested combination floating structure may be a useful offshore structure for constructing a very large floating structure.

A Study on the Speaker Adaptation in CDHMM (CDHMM의 화자적응에 관한 연구)

  • Kim, Gwang-Tae
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.39 no.2
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    • pp.116-127
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    • 2002
  • A new approach to improve the speaker adaptation algorithm by means of the variable number of observation density functions for CDHMM speech recognizer has been proposed. The proposed method uses the observation density function with more than one mixture in each state to represent speech characteristics in detail. The number of mixtures in each state is determined by the number of frames and the determinant of the variance, respectively. The each MAP Parameter is extracted in every mixture determined by these two methods. In addition, the state segmentation method requiring speaker adaptation can segment the adapting speech more Precisely by using speaker-independent model trained from sufficient database as a priori knowledge. And the state duration distribution is used lot adapting the speech duration information owing to speaker's utterance habit and speed. The recognition rate of the proposed methods are significantly higher than that of the conventional method using one mixture in each state.

The Surgical Treatment of Esophageal Perforation (식도 파열의 수술적 치료)

  • Hwang Jung Joo;Joung Eun Kyu;Lee Doo Yun;Paik Hyo Chae
    • Korean Journal of Bronchoesophagology
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    • v.11 no.1
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    • pp.15-20
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    • 2005
  • Background : It is well-known that esophageal perforation (EP) is difficult in diagnosis and has high mortality rate despite proper management. There are disputes in regarding the reatment in cases of delayed diagnosis although in the early diagnosed cases, operation is recommended without arguments. Methods: From April, 2001 to December, 2004, nine patients who were diagnosed as EP in our hospital were analyzed retrospectively about the causes, the interval between the cause and the treatment, and operation methods. Results: There were 8 male and one female with men age of 49.3 years (range: 25-67 years). The causes of EP included perforations following operations of corvical spine in three cases, spontaneous perforation(Boehaave syndrome) in two cases, foreign bodies in two cases, operation of esophageal diverticulum in one case and blunt trauma bytraffic accident in one case. Mean interval between the first treatments and the causes was 11.6 days (range: 2-30 days). The sites of perforation were upper third of esophagus in three cases, middle third in three cases and lower third in three cases. All except two cervical cases presented as mediastinitis or empyema at the time of diagnosis. Primary repair and irrigation had been performed in 7 cases but five cases out of them required more than two procedures. Conclusions : More than one procedure wasrequired in the treatment of EP because of contaminations and infections which had been spread at the time of initial manifestatios, howeverprimary closure and massive irrigation is the best method in order to preserve esophagus unless the remaining esophagus is extensively damaged.

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A Study on the Construction of Port Communication Infra based on Mesh Network (Mesh Network 기반의 항만통신 인프라 구축방안)

  • Choi, Hyung-Rim;Lee, Doo-Won;Yoo, Dong-Ho;Kwon, Hae-Kyoung;Jeon, Yong-Sik;Lee, Ho-In
    • Journal of Korea Port Economic Association
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    • v.25 no.2
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    • pp.259-276
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    • 2009
  • The study herein has focused on offering foundation infrastructure in order for seamen who arrive at Korean ports to use internet service smoothly in waiting time and free time. It also concentrated on how to build communication infrastructure for efficient operations when improving existing ports and developing new ports. For this, it has grasped the tendency of researches concerning the existing port communication and has also investigated the status and problems of communication infrastructure being used currently in ports. So it has suggested several realistic development methods based on mesh network and has reviewed them in terms of the stability, economic feasibility and efficiency. Additionally, this research offers the results of the performance test conducted on major equipment in market by the suggested methods. This research can be a good guideline in building wireless communication systems of ports and is expected to contribute to creating traffic volume by improving the image of ports.

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Limits and improvements of the river master plan with the change of public water management system (물관리 체계 개편에 따른 하천기본계획의 한계 및 개선방안)

  • Lee, Du Han;Kim, Ji Sung
    • Proceedings of the Korea Water Resources Association Conference
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    • 2020.06a
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    • pp.6-6
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    • 2020
  • 하천관리정책은 국가의 자연적, 사회적 환경에 크게 영향을 받으며 각 나라에 맞는 고유한 방향으로 정착하였다. 우리나라의 경우 치수와 개발이 중심이 있는 되는 일본식 하천관리체계를 오랫동안 유지하여 왔으며 개별 하천의 관리에 기본이 되는 하천기본계획체계는 일본의 신하천법의 형식을 유지하고 있다. 이에 반해 물관리체계는 2019년 6월에 시행된 물관리기본법에 의해 수량과 수질 통합관리 체계로 크게 개편되었다. 현행 물관리체계에서는 수질과 수량은 관리주체가 통합되었으나 하천관리는 하천시설물과 하천수의 관리주체가 분리되어 있다. 기후변화로 인해 주요 선진국은 하천관리에서 치수의 중요성이 높아지고 있으나 우리나라의 경우에는 하천의 치수관리에 대한 정책적 중요도는 떨어지고 있으며 환경관리에 대한 중요도가 높아지고 있다. 하천기본계획은 개별 하천에 대한 치수, 이수, 환경의 유일한 종합적 계획으로 광범위한 조사/분석/계획 등을 포함하고 있으나 타계획과의 연관성이나 활용성이 높지 않은 편이다. 본 연구에서는 국가 차원의 종합적인 하천관리정책 수립, 일관성 있는 치수, 이수, 환경 계획의 수립, 정부의 효율적인 하천관리 실행 등의 관점에서 현행 하천기본계획의 한계를 살펴보고 변화하는 기후 및 사회 환경에 탄력적으로 대응할 수 있는 개선방안을 검토하였다. 이를 위해서 우리나라와 일본, 미국, 유럽 등 선진국의 하천관리체계를 검토하고 도로, 상하수도 등 유사 분야의 계획 체계와 하천계획 체계를 비교하였다. 물관리 체계 개편을 고려한 현행 하천기본계획의 주요 논점을 정리하고 현행 법체계와 사회환경을 고려하여 하천기본계획이 실질적인 하천에 대한 종합적 계획의 의미를 살릴 수 있는 체계 개편 방안과 구체적인 실행방안에 대해서 고찰하였으며 장단기 개선방안을 제시하고자 한다.

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A Study on Elastic Shear Buckling Coefficients of Horizontally Curved Plate Girder Web Panels (강곡선 플레이트거더 복부판의 전단좌굴계수에 관한 연구)

  • Lee, Doo-Sung;Lee, Sung-Chul
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.28 no.3A
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    • pp.367-373
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    • 2008
  • In the design of horizontally curved plate girder web panels, it is required to evaluate accurately the elastic buckling strength under pure shear. Currently, elastic shear buckling coefficients of curved web panels stiffened by transverse intermediate stiffeners are determined by assuming conservatively that straight web panels without curvature are simply supported at the juncture between the flange and web. However, depending upon the geometry and the properties of the curved plate girder, the elastically restrained support may behave rather closer to a fixed support. The buckling strength of curved girder web is much greater (maximum 38%) than that of a straight girder calculated under the assumption that all four edges are simply supported in Lee and Yoo (1999). In the present study, a series of numerical analyses based on a 3D finite element modeling is carried out to investigate the effects of geometric parameters on both the boundary condition at the juncture and the horizontal curvature of web panel, and the resulting data are quantified in a simple design equation.

Experimental Study on Ultimate Shear Strength of Horizontally Curved Plate Girder Web Panels (강곡선 플레이트거더 복부판의 극한전단강도에 관한 실험연구)

  • Lee, Doo Sung;Park, Chan Sik;Lee, Sung Chul
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.26 no.4A
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    • pp.727-734
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    • 2006
  • Although a limited number of experimental investigations and finite element analyses revealed that a curved web panel in practical design has a considerable reserve strength after the elastic buckling as a straight girder web panel, the current Guide Specifications for Horizontally Curved Steel Girder Highway Bridges (AASHTO, 2003) do not consider the postbuckling strength in the ultimate shear strength due to lack of a comprehensive study. In this study, the ultimate shear strength behavior of horizontally curved steel web panels was investigated through nonlinear finite element analysis and experimental test. It was found that curved web panels used in practical designs are able to develop the postbuckling strength that is equivalent to that of straight girder web panels having the same dimensional and material properties.

Earthquake Resistance of Modular Building Units Using Load-Bearing Steel Stud Panels (내력벽식 스터드패널을 적용한 모듈러건물유닛의 내진성능)

  • Ha, Tae Hyu;Cho, Bong-Ho;Kim, Tae Hyeong;Lee, Doo Yong;Eom, Tae Sung
    • Journal of Korean Society of Steel Construction
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    • v.25 no.5
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    • pp.519-530
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    • 2013
  • Cyclic tests on modular building units for low-rise buildings composed of stud panels and a light-weight steel perimeter frame, were performed to evaluate the earthquake resistance such as stiffness, load-carrying capacity, ductility, and energy dissipation per load cycle. The strap-braced and sheeted stud panels were used as the primary lateral load-resistant element of the modular building units. Test results showed that the modular building units using the strap-braced and sheeted stud panels exhibited excellent post-yield ductile behaviors. The maximum drift ratios were greater than 5.37% and the displacement ductility ratios were greater than 5.76. However, the energy dissipation per load cycle was poor due to severe pinching during cyclic loading. Nominal strength, stiffness, and yield displacement of the modular building units were predicted based on plastic mechanisms. The predictions reasonably and conservatively correlated with the test results. However, the elastic stiffness of the strap-braced stud panel was significantly overestimated. For conservative design, the elastic stiffness of the strap-braced stud panel needs be decreased to 50% of the nominal value.

Effect of Long-Term Pyridoxine Depletion on Asparte Aminotransferase and Pyridoxal 5'-Phosphate of Rat Liver Mitochondrial and Cytosolic Fractions (장기간의 Pyridoxine 부족이 쥐 간의 Mitochondria 및 Cytosolic Fraction 에 있는 Aspartate Aminotransferase 및 Pyridoxal 5'- Phoshate에 미치는 영향)

  • 임경숙
    • Journal of Nutrition and Health
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    • v.19 no.4
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    • pp.246-254
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    • 1986
  • Weanling female Sprague Dawley rats were fed d diets containing 22mg pyridoxine. BCI/kg diet (control diet) and l.2mg pyridoxine. BCI/kg diet (deficient diet). One control group and one defi­c dent group were fed their diet throughout growth, g gestation and lactation. After the pups were born and weaned, the deficient group was divided into two groups. One switched to control diet(supple­I mented group) and the other continued the same d deficient diet( deficient group) until 10 week -old. The liver mitochondrial and cytosolic asparate a aminotransferase activity and pyridoxal phosphate content were determined in offspring rats. The aspartate aminotransferase activities in both liver mito$\phi$ondrial and cytosolic fractions of den­d cient group were significantly lower than those of controls, but there were no significant differences between two groups after addition of 1O^{-4}M pyri­d do뼈I phosphate to the medium. By pyridoxine s supplementation after weaning, the reduced aspar­a tate aminotnmsferase activities were only partialy I restored to control levels. The pyridoxal phospha­t te content of deficient group in Iiver mitochondr­ial and cytosoIic fractions were alo significantly different from those of controls, but readily restored by dietary supplementation. These results suggest that there is a quantitative and a qualitative changes of aspartate amino trans­f ferase and pyridoxal phosphate in liver mitochon­d drial and cytosolic fraction by long-term pyrido­x xine deficiency and these reductions can partially recovered by dietary pyridoxine supplementation after weaning.

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