• Clinical and Experimental Pediatrics
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• v.51 no.9
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• pp.956-963
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• 2008

Purpose : Indomethacin is widely used for the prophylaxis and treatment of patent ductus arteriosus (PDA); however, it is associated with side effects such as renal failure, intraventricular hemorrhage, and gastrointestinal bleeding. Intravenous ibuprofen has been shown to be as effective as indomethacin in prompting PDA closure. If treatment with oral ibuprofen is as effective as indomethacin, it would have the advantages of greater availability, simpler administration, and lower cost. We conducted this study to compare the efficacy and side effects of indomethacin with those of oral ibuprofen, vis-$\grave{a}$-vis on the pharmacological closure of PDA. Methods : As a randomized double-blind study, 34 preterm infants with respiratory distress syndrome and hemodynamically significant PDA were treated with either intravenous indomethacin or oral ibuprofen. Echocardiography was performed by one cardiologist who was blind to the treatment that any given infant received. The rate of ductal closure, the need for additional drug treatment or surgical ligation, clinical outcome, and the side effects of drug treatment were compared. Results : Ductal closure occurred in 16 of 18 patients (88.9%) from the indomethacin group and in 14 of 16 patients (87.5%) from the ibuprofen group (P>0.05). Three patients in the indomethacin group and four in the ibuprofen group required a second drug treatment (P>0.05). Three patients (i.e., one patient in the indomethacin group and two in the ibuprofen group) underwent surgical ligation (P>0.05). Between the two groups, there was no significant difference vis-$\grave{a}$-vis in side effects or clinical outcome. Conclusion : Compared to indomethacin, oral ibuprofen has the advantages of simpler administration and lower cost, while being as effective; in addition, there are no differences between the two drug treatments with regards to side effects or clinical outcomes. Therefore, the widespread use of oral ibuprofen should be considered in treating PDA in preterm infants.

• Journal of Chest Surgery
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• v.32 no.4
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• pp.353-357
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• 1999

Background: Mitral valve replacement(MVR) with chordal preservation in patients with mitral vlavular disease has been proven to be beneficial for left ventricular function and for reduction of postoperative complication. Material and Method: From January 1995 to July 1996, the early postoperative results of mitral valve replacement were compared between 20 patients who underwent chordae resection(classic MVR group) and 10 patients who underwent chordae preservation(preservation MVR group) in the Department of Thoracic and Cardiovascular Surgery, Chunbuk National University Hospital. Result: There was no significant difference between the two groups in age, sex, NYHA functional class, cardiothoracic ratio, echocardiographic finding, cardiopulmonary bypass time and aortic cross clamping time. The difference between preoperative and postoperative cardiothoracic ratio after 3 months was not statistically significant. At echocardiographic left ventricular evaluation, ejection fraction and fractional shortening decreased slightly in the preservation group then preoperative value (p=0.47, p=0.12), however, decreased significantly in the classic MVR group(p=0.03, p=0.04), and were statistically significant between the two groups(p=0.03, p=0.02). Conclusion: We conclude that MVR with chorda preservation seems to have a beneficial effect on postoperative left ventricular performance in mitral valve disease than the classic MVR.

• Science of Emotion and Sensibility
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• v.17 no.2
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• pp.101-110
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• 2014

High-frequency is sound produced in non-audible area, which couldn't be heard in daily life. The frequency range above 22Khz is called 'high-frequency' and its components are called 'HFC(High-Frequency Components)'. It is known that ocean wave sound is rich in HFC, because it brings serenity and causes ${\alpha}$-waves in human mind. When this natural sound is combined with high-frequency, it seems to give a pleasurable feeling, indicated by an ${\alpha}$-wave increase and a ${\beta}$-wave decrease. We call this phenomena "the hypersonic effects". In this experiment, subjects listened to the ocean wave sound simultaneously with corresponding frequencies similar to ocean wave frequency components created artificially in a electric circuit. Brain waves were measured by an EEG system with 8 channels using 8 electrodes on Fp1, Fp2, F3, F4, T3, T4, O1, and O2. The results showed that ${\alpha}$-wave increase and ${\beta}$-wave decrease were statistically significant while subjects were listening to the ocean wave sound along with the high frequency components, reflecting the hypersonic effect.

• Economic and Environmental Geology
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• v.48 no.5
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• pp.379-390
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• 2015

Multibeam backscatter strength is dependent not only on seafloor sediment facies but also on changed incidence angle due to the actual bottom slope. Therefore, the correction for actual bottom slope should be considered before the analysis of backscatter strength. This paper demonstrates the backscatter correction technique for the actual incidence angle and ensonified area. The target area is a part of the eastern Yellow Sea with water depths of 46~55 m. The area is located between the sand ridges and covered by large dunes with various bottom slopes. The dunes usually have the gentle slopes of about $1{\sim}3^{\circ}$, but show some steep slopes of $5{\sim}15^{\circ}$ on the crest. The backscatter strength values on the crest range from -34 to -23 dB, assuming that the bottom is flat. However, this study shows that the backscatter strength range was somewhat reduced (-32~-25 dB) after correction for actual bottom slope. In addition, the backscatter imagery was significantly improved; high and low backscatter strength values on the crest due to the actual bottom slope were normalized. The results demonstrate that the correction technique in this study is an effective tool for processing backscatter strength.

• Proceedings of the Acoustical Society of Korea Conference
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• autumn
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• pp.183-186
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• 2000

본 논문에서는 인식이 진행되는 동안 탐색 공간을 효과적으로 줄임으로써 음성인식의 고속화를 달성할 수 있는 새로운 프레임 단위 적응 프루닝 알고리즘을 제안하고 실험을 통하여 그 유효성을 확인하였다. 이것은 앞 프레임과 뒤 프레임 사이의 최대확률은 높은 상관성을 가지므로 프루닝 문턱치를 앞 프레임의 최대 확률로부터 효과적으로 구할 수 있다는 사실에 근거를 두고있다. 이 방법에서는 앞 프레임의 최대 우도 확률과 후보 확률들의 조합으로 현재 프레임의 프루닝 문턱치를 갱신함으로써 현재 프레임의 문턱치를 인식 과정 중에 얻을 수 있기 때문에, 인식 태스크가 바뀌어도 문턱치를 구하기 위한 사전 실험을 수행할 필요가 없게 된다. 또한, 프레임 단위로 적응적으로 얻어진 문턱치는 다른 환경 하에서도 인식 속도의 향상을 가져올 수 있게 된다. 제안된 알고리즘의 유효성을 확인하여 위하여 한국어 주소 인식 시스템에 적용하였다. 본 시스템은 48개의 유사음소단위(PLUs)를 인식의 기본단위로 하고, 적응알고리즘으로는 최대사후확률추정법((MAP: Maximum A Posteriori Probability Estimation)을, 인식 알고리즘으로는 OPDP(One Pass Dynamic Programming)법을 이용하였다 남성화자 3인이 25개의 연결 주소명을 대상으로 인식 실험을 수행한 결과, 제안된 프레임단위 적응프루닝 문턱치를 적용한 경우를 기존의 고정 프루닝 문턱치와 가변 프루닝 문턱치를 적용한 경우와 비교하였을 때 인식률의 변화 없이 탐색공간이 상대적으로 각각 $14.4\%와 $9.14\%가 감소되어 제안된 프레임 단위 적응 프루닝 알고리즘의 유효성을 확인할 수 있었다. 시,공간적 분포 특성이 구체적으로 규명되면 보다 정확한 음장변화 추정이 이뤄져야 할 것으로 보인다. 또한 내부파와 음파의 상대적인 진행 방향에 따라 음장변화가 크게 다를 것이 예상되므로 이를 규명하기 위해서는 궁극적으로 3차원적인 음장분포 연구가 필요하다. 음향센서를 해저면에 매설할 경우 수충의 수온변화와 센서 주변의 수온변화 사이에는 어느 정도의 시간지연이 존재하게 되므로 이에 대한 영향을 규명하는 것도 센서의 성능예측을 위해서 필요하리라 사료된다.가지는 심부 가스의 개발 성공률을 증가시키기 위하여 심부 가스가 존재하는 지역의 지질학적 부존 환경 및 조성상의 특성과 생산시 소요되는 생산비용을 심도에 따라 분석하고 생산에 수반되는 기술적 문제점들을 정리하였으며 마지막으로 향후 요구되는 연구 분야들을 제시하였다. 또한 참고로 현재 심부 가스의 경우 미국이 연구 개발 측면에서 가장 활발한 활동을 전개하고 있으며 그 결과 다수의 신뢰성 있는 자료들을 확보하고 있으므로 본 논문은 USGS와 Gas Research Institute(GRI)에서 제시한 자료에 근거하였다.ऀĀ耀Ā삱?⨀؀Ā Ā?⨀ጀĀ耀Ā?돀ꢘ?⨀硩?⨀ႎ?⨀?⨀넆돐쁖잖⨀쁖잖⨀／ࠐ?⨀焆덐瀆倆Āⶇ퍟ⶇ퍟ĀĀĀĀ磀鲕좗?⨀肤?⨀⁅Ⴅ?⨀쀃잖⨀䣙熸ጁ↏?⨀

• Journal of the Korea Society for Simulation
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• v.30 no.2
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• pp.11-22
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• 2021

Sonobuoy is widely used as a very important sensor in combat management system using P-3 patrol aircraft due to its advantages of rapid searching into wide exploration range. It is necessary to verify the performance of developed sonobuoy system using various maritime test data in order to be successfully applied in combat management system. But it is difficult to acquire various real maritime data because it needs much time and effort. Therefore we have developed in this paper a synthetic signal generator and a simulator that they can verify the performance of sonobuoy system and evaluate its operational effectiveness without conducting maritime test. We have synthesized target signals based on the characteristics of underwater sound sources, and then developed the synthesized signal generator which consider to sound propagation etc. like as underwater environment. And in the simulator development we use a HMI technique to enhance the convenience of operator, and design to verify the performance of sonobuoy system. The developed signal generator and simulator can be used as useful tools to evaluate the operational effectiveness such as optimal deployment of sonobuoy in combat management system using P-3 patrol aircraft.

• Journal of the Korean Society of Marine Environment & Safety
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• v.29 no.5
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• pp.512-519
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• 2023

Noise pollution poses significant challenges to human well-being and marine ecosystems. It is primarily caused by the flow around ships and marine installations, emphasizing the need for accurate noise evaluation of flow noise to ensure environmental safety. Existing flow noise analysis methods for underwater environments typically use a hybrid method combining computational fluid dynamics and Ffowcs Williams-Hawkings acoustic analogy. However, this approach has limitations, neglecting near-field effects such as reflection, scattering, and diffraction of sound waves. In this study, an alternative using direct method flow noise analysis via the lattice Boltzmann method (LBM) is incorporated. The LBM provides a more accurate representation of the underwater structural boundaries and acoustic wave effects. Despite challenges in underwater environments due to numerical instabilities, a novel DM-TS LBM collision operator has been developed for stable implementations for hydroacoustic applications. This expands the LBM's applicability to underwater structures. Validation through flow noise analysis in pipe orifice demonstrates the feasibility of near-field analysis, with experimental comparisons confirming the method's reliability in identifying main pressure peaks from flow noise. This supports the viability of near-field flow noise analysis using the LBM.

• Journal of Chest Surgery
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• v.37 no.9
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• pp.735-741
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• 2004

Blood cardioplegia is known as an established cardioplegic solution during open heart surgery. Recently, the Histidine-Tryptophan-Ketoglutarate (HTK) solution has been introduced as a cardioplegia in Korea. This study was designed to compare the myocardial protective effect between the cold blood cardioplegia (CBC) and HTK solution. Material and Method: Forty patients who underwent valve surgery or coronary artery bypass surgery were randomly divided into CBC group (n=20) and HTK group (n=20). The perioperative hemodynamic and clinical data were analyzed. The concentration of CK-MB, Troponin 1 and Lactate from coronary sinus and radial arterial blood were compared for the evaluation of the myocardial damage. The postoperative serial CK-MB levels were measured. Result: The characteristics of preoperative patients were similar in two groups. The hemodynamic parameters and postoperative clinical data were also similar between the two groups. There were no statistical significances between the CBC and HTK group in the difference of biochemical markers: Δ CK-MB (15.3$\pm$26.0 vs 19.3$\pm$14.3), ΔTro-1 (2.4$\pm$4.9 vs 2.0$\pm$2.20), ΔLac (1.6$\pm$1.0 vs 1.9$\pm$2.5). The serial CK-MB levels were not significantly different between the two groups. Conclusion: These results suggested that the myocardial protective effect of HTK solution was similar to cold blood cardioplegia during open heart surgery.

• Journal of Korea Multimedia Society
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• v.9 no.7
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• pp.808-817
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• 2006

Although the generally used the velocity index of doppler effect is a very significant factor in the functional evaluation of the left ventricle, it depends on the subjective evaluation of an inspector. The objective data of the motility can be obtained from the gated myocardial SPECT images by quantitative analysis. However, it is difficult to image visual of the velocity of the motion. The aim of our study is to develop a new method for the imaging velocity using the gated myocardial SPECT images and use it as an evaluation index for analyzing motility. First we visualized left ventricle into 3 dimensions using the coordinates of the points which were obtained through a segmentation of myocardium. Each point was represented by the different colors, according to the velocity of each point. We performed a validation study using 7 normal subjects and 15 myocardial infarction patients. To analyze motility, we used the average of the moved distance and the velocity. In normal cases, the average of the moved distance was 4.3mm and the average of the velocity was 11.9mm. In patient cases, the average of the moved distance was 3.9mm and the average of the velocity was 10.5mm. These results show that the motility of normal subjects is higher than the abnormal subjects. We expect that our proposed method could become a way to improve the accuracy and reproducibility for the functional evaluation of myocardial wall.

• Geophysics and Geophysical Exploration
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• v.14 no.1
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• pp.18-24
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• 2011

A multi-channel seismic reflection (MCS) survey was conducted in 2009 to explore the deep crustal structure of the Pacific Plate south of Hokkaido. The survey line happened to traverse a 250-km-wide Warm Core Ring (WCR), a current eddy that had been generated by the Kuroshio Extension. We attempted to use these MCS data to delineate the WCR fine structure. The survey line consists of two profiles: one with a shot interval of 200m and the other with a shot interval of 50 m. Records from the denser shot point line show much higher background noise than the records from the sparser shot point line. We identified the origin of this noise as acoustic reverberations between the sea surface, seafloor and subsurface discontinuities, from previous shots. Results showed that a prestack migration technique could enhance the signal buried in this background noise efficiently, if the sound speed information acquired from concurrent temperature measurements is available. The WCR is acoustically an assemblage of concave reflectors dipping inward, with steeper slopes (${\sim}2^{\circ}$) on th ocean side and gentler slopes (${\sim}1^{\circ}$) on the coastal side. Within the WCR, we recognised a 30-km-wide lens-shaped structure with reflectors on the perimeter.