• Title/Summary/Keyword: 유전적 상관관계

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A Report on the Inter-Gene Correlations in cDNA Microarray Data Sets (cDNA 마이크로어레이에서 유전자간 상관 관계에 대한 보고)

  • Kim, Byung-Soo;Jang, Jee-Sun;Kim, Sang-Cheol;Lim, Jo-Han
    • The Korean Journal of Applied Statistics
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    • v.22 no.3
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    • pp.617-626
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    • 2009
  • A series of recent papers reported that the inter-gene correlations in Affymetrix microarray data sets were strong and long-ranged, and the assumption of independence or weak dependence among gene expression signals which was often employed without justification was in conflict with actual data. Qui et al. (2005) indicated that applying the nonparametric empirical Bayes method in which test statistics were pooled across genes for performing the statistical inference resulted in the large variance of the number of differentially expressed genes. Qui et al. (2005) attributed this effect to strong and long-ranged inter-gene correlations. Klebanov and Yakovlev (2007) demonstrated that the inter-gene correlations provided a rich source of information rather than being a nuisance in the statistical analysis and they developed, by transforming the original gene expression sequence, a sequence of independent random variables which they referred to as a ${\delta}$-sequence. We note in this report using two cDNA microarray data sets experimented in this country that the strong and long-ranged inter-gene correlations were still valid in cDNA microarray data and also the ${\delta}$-sequence of independence could be derived from the cDNA microarray data. This note suggests that the inter-gene correlations be considered in the future analysis of the cDNA microarray data sets.

Three Species Associations with Spatial Autocorrelation Analysis in Community (군락내 공간적 분석에 의한 세 종간 상관관계)

  • 허만규;허홍욱;김창호
    • The Korean Journal of Ecology
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    • v.23 no.1
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    • pp.17-23
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    • 2000
  • The spatial distribution of allelic frequencies was studied in the natural population of three species (Ligustrum obtusiflolium, Alnus japonica, and Pinus densflora). The distributional patterns of the crown-cover centers were compared between two populations in forests. L. obtusifolium and p. densiflora showed a significantly positive spatial autocorrelation as measured by Moran's I. In P densiflora, the genetic similarity was shown by individuals within up to a scale of 18 m distance and this is partly due to combination of pollen dispersal and long distance seed dispersal by wind or men. In L. obtusifolium, population structure in the distribution of allelic frequencies is related to mating systems and is consisted of a scale of 12.5 m intervals. No spatial structuring of allele frequencies was found for polymorphic enzyme loci within a natural population of Alnus japonica. The results also in- dicate that positive associations between L. obtusifolium and P densiflora can occur when both select the same habitat or have the same environmental requirements.

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Analysis of the hereditary factor in craniofacial morphology and fingerprints in Class III malocclusion (III급 부정교합에서 두개안면 형태와 지문의 유전성향 분석)

  • Oh, Tae-Kyung;Baik, Hyoung-Seon
    • The korean journal of orthodontics
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    • v.34 no.4 s.105
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    • pp.279-287
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    • 2004
  • In growing patients with Class III malocclusion, the various patterns of maxillofacial growth are a key element that affects the success or failure of treatment. Therefore it is important to correctly predict maxillofacial growth before initiating treatment. The purpose of this study was to find out the correlation between the maxillofacial morphology of parents and their Class III children by analyzing lateral cephalograms and hereditary factors. Among Class III preadolescent children, 50 families were obtained. To find out the specific hereditary factors involved, fingerprints were obtained and genetic correlation with the maxillofacial morphology was analyzed. The following conclusions were made. 1. A significant correlation (P<0.05-0.00l) was found in many of the cephalometric measurements between the offspring and their parents. The correlation in the skeleton measurements was higher than in the denture measurements. The father-offspring correlation was higher than the mother-offspring correlation 2. A significant correlation (P<0.05-0.00l) was found in fingerprint units between the offspring and their parents. The mother-offspring correlation was higher than the father-offspring correlation. 3. Between the maxillofacial morphology and fingerprint units, there was significant genetic correlation (P<0.05-0.01). Based on the analysis of genetic correlation, higher correlation was found in the parent-son pairing than the parent-daughter pairing.

Correlation of Forearm Circumference; With Hand Grip Strength (전완 원주와 악력과의 상관관계)

  • Cynn, Heon-Seock
    • Journal of Korean Physical Therapy Science
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    • v.8 no.2
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    • pp.1047-1050
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    • 2001
  • 이 연구의 목적은 전완 원주와 악력과의 상관관계를 알아보는 것이다. 오른손잡이 여성 30명이 이 연구에 참여하였으며, 연구의 대상자의 평균 연령은 31.0세였다. 전완 원주는 척골의 주두와 경상돌기의 1/2 지점과 근위 3/4 지점에서 줄자를 이용하여 측정하였다. 악력은 미국 수부 치료사 협회의 기준에 의하여 Jarmar dynamometer를 사용하여 측정하였다. 통계학적 분석은 피어슨 상관 관계 계수를 이용하여 상관관계를 조사하였다. 전완 두 지점에서 측정된 원주와 악력간에는 낮은 상관관계를 나타내었다(r=.02. p=.921; r=.02, p=.928). 연구 대상자 30명 중 정기적으로 상체 운동을 하는 18명의 연구 대상자들의 전완 두 지점에서도 낮은 상관 관계를 나타내었다(r=.16, p=.521: r=.18, p=.468). 본 연구의 결과는 선행된 다른 연구 결과와는 상이하게 높은 상관관계를 나타내지 않았다. 그 이유로는 본 연구에서 악력에 영향을 주는 여러 가지 요소들(신체 유형, 운동 습관. 직업 피하 지방성분, 유전적 요소 등)의 측정이 고려되지 않았고. 연구 대상자의 수(n=30)가 적었다는 점을 들 수 있다.

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Estimation of Genetic Parameters for Growth and Egg Production Traits in Black Korean Native Chicken and Korean White Leghorn Populations (흑색한국재래닭, 한국화이트레그혼 집단의 산육 및 산란 형질 유전모수 추정)

  • Cha, Jaebeom;Kim, Kigon;Choo, Hyojun;Kwon, Il;Park, Byeongho
    • Korean Journal of Poultry Science
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    • v.47 no.4
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    • pp.267-274
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    • 2020
  • This study was conducted to estimate genetic parameters for growth and egg production traits in Black Korean native chicken (L strain) and Korean White Leghorn (F, K strains) using a multi-traits animal model BLUP. Traits used for this study were body weight at 150 days (BW150) and 270 days (BW270), age at first egg (DAY1st), egg weight at first egg (EW1st) and 270 days (EW270), and number of eggs laid by 270 days (EP270), and included 68,688 pedigree and 123,905 performance records collected from 2001 to 2013. In L, F, K strains, heritability estimates of BW150 were high (0.48, 0.52 and 0.50, respectively); of BW270 were high (0.56, 0.57 and 0.56); of DAY1st were medium to high (0.45, 0.39 and 0.31); of EW1st were low (0.15, 0.16 and 0.15); of EW270 were high (0.58, 0.55 and 0.59) and of EP270 were moderate (0.22, 0.21 and 0.20). The genetic and phenotypic correlation of DAY1st with EP270 were highly negative (-0.73 to -0.63 and -0.48 to -0.42). The genetic and phenotypic correlation of EP270 with BW150 and BW270, respectively were low negative (-0.16 to 0.01 and -0.14 to -0.03) and low to moderate positive (-0.08 to 0.07 and -0.13 to 0.04). The genetic and phenotypic correlation of EW270 with BW150 and BW270, respectively were moderate to high positive (0.39 to 0.49 and 0.36 to 0.46) and (0.29 to 0.33 and 0.34 to 0.37). The study showed that there is a potential for genetic improvement of Korean Indigenous chicken through selection program.

Genetic relationship of Aloe vera 'Saengjang', a new forma, based on cpDNA and ITS sequence variation (cpDNA와 ITS 염기변이에 근거한 신품종 생장알로에 유전적 상관관계)

  • Srikanth, Krishnamoorthy;Jang, Seon Il;Whang, Sung Soo
    • Korean Journal of Plant Taxonomy
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    • v.44 no.4
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    • pp.250-256
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    • 2014
  • This study was carried out to understand the genetic relationship of three Aloe spp. cultivated in Korea, A. saponaria, A. vera and A. arborescens and a new variant in Korea based on three plastid (matK, trnL-F, rbcL) and one nuclear (ITS regions) DNA barcode markers. A total of 2,420 bp sequence was amplified. Two indels were detected in the trnL region, and also several species specific nucleotide loci were detected in all 29 parsimonious informative sites, and 148 variable sites were detected among four taxa studied while 170 variable and 75 parsimonious sites were detected when other Aloe spp. in worldwide were used. An UPGMA phenogram with 10,000 bootstrap replication showed that the new variant was closest to A. vera. The variant was not morphologically and genetically concurrent with any reported species so far. The clustering of Aloe species were broadly in agreement with previously reported results.

Estimation of Heritability and Genotypic Correlation through Diallel Corsses of the Silkworm, Bombyx mori L. (가잠 F1세대에 있어서 몇 가지 양적 형질에 대한 유전력 및 유전상관의 추정)

  • 정원복;장권열
    • Journal of Sericultural and Entomological Science
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    • v.28 no.2
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    • pp.21-27
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    • 1986
  • Since the estimate of the genetic relations between characters gave us effective basic informations about the selection of good strains of silkworm, the experiment was carried out to estimate the heritability and the genotypic correlation, etc. using the 21 combinations F1, 's by diallel crosses of seven strains of the silkworm. As the result of this experiment some conclusions obtained were as follows ; 1. The genotypic correlation is estimated highly positive in the heritability for all the 9 characters. 2. The correlations between all the characters are positive and the genotypic correlation is generally higher than the phenotypic one. 3. Since all the correlations between the have length and other characters are highly positive, it can be considered that the effects of the other characters on the have length are very important.

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A Study on Dielectrical Constant under Ground Conditions (지반조건에 따른 유전상수 변화에 관한 연구)

  • Cho, Jinwoo;Cho, Wonbeom;Kim, Jinman;Choi, Bonghyuck
    • Journal of the Korean GEO-environmental Society
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    • v.13 no.12
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    • pp.17-25
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    • 2012
  • In this study, dielectrical constant of the ground was measured using TDR method and correlated with water contents and density of ground. In order to evaluate the applicability as a cavity exploration, model experiments were carried out to analyze the effects of cavity size on the dielectrical constant. Test result indicated that dielectrical constant of the ground tended to linearly increase with the increase in water contents and density, which can be represented in a certain relational expression. Also, the dielectrical constant of ground varied sensitively with the cavity size of ground. The results conclude that the dielectrical constant, water contents and density of the ground proved to have a correlation among them, and the dielectrical constant is expected to be a basic data on cavity exploration.

Statistical Genetic Studies on the Selection for Grain Characteristics of Malting Barley (Hordeum distichum L.) (맥주맥(Hordeum distichum, L.)의 우량품종 육성에 있어서 입형질의 선발에 관한 통계유전학적 연구)

  • Bong-Ho Lee;In-Gul Lee
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.21 no.1
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    • pp.71-81
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    • 1976
  • This study was carried out to attain the selection information on grain characters of malting barley. Indirect selection, making use of information on grain thickness, seemed to be an effective method for the selection of 1, 000 grain weight, grain hull and grain yield which were directly affected by grain thickness. Grain yield which had a direct effect on grain, meal and protein content seemed to be an effective selection indicator for them, however, a better method is expected upon improvement of indirect effects of hull and grain yield.

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