• Proceedings of the Korean Society of Crop Science Conference
• /
• 2023.04a
• /
• pp.146-146
• /
• 2023

• Proceedings of the Korean Information Science Society Conference
• /
• 2002.10c
• /
• pp.76-78
• /
• 2002

본 논문에서는 지역사회 유전체역학센터 및 질환군별 유전체연구센터로부터 수집되는 한국인 유전체 시료와 이에 관련된 시료 접수 정보, 시료 보관 위치 정보, 시료 정도 관리(Quality Control) 정보, 분양 정보 등을 체계적으로 저장ㆍ관리하기 위하여 시료 정보 관리 시스템을 구축하였다. 시료 접수자 및 정보 관리자는 시료 정보 관리 시스템을 통해 인간의 DNA, cell, serum, urine 등과 같은 유전체 시료를 접수하고 관리할 수 있으며 이들 정보에 대한 집계 현황을 참조할 수 있다. 또한, 지역사회 유전체역학센터 및 질환군별 유전체연구센터에서 입력한 개인식별 정보, 임상 정보, 생활습관 정보 등과 유전체 시료 정보와의 연계가 가능하다. 이는 관련 연구진에게 인간 유전체 시료를 활용할 수 있는 기반을 제공함으로써 유전체 연구의 활성화에 기여할 수 있다.

• Journal of Genetic Medicine
• /
• v.8 no.2
• /
• pp.89-99
• /
• 2011

Over the years Korean health care system has improved in delivery of quality care to the general population for many areas of the health problems. The system is now being recognized in the world as the most cost effective one. It is covered by the uniform national health insurance policy for which most people in Korea are mandatory policy holders. Genetic counseling service, however, which is well recognized as an integral part of clinical genetics service deals with diagnosis and management of genetic condition as well as genetic information presentation and family support, is yet to be delivered in comprehensive way for the patients and families in need. Two major obstacles in providing genetic counseling service in korean health care system are identified; One is the lack of recognition for the need for genetic counseling service as necessary service by the national health insurance. Genetic counseling consumes a significant time in delivery and the current very low-fee schedule for physician service makes it very difficult to provide meaningful service. Second is the critical shortage of qualified professionals in the field of medical genetics and genetic counseling who can provide the service of genetic counseling in clinical setting. However, recognition and understanding of the fact that the scope and role of genetic counseling is expanding in post genomic era of personalized medicine for delivery of quality health care, will lead to the efforts to overcome obstacles in providing genetic counseling service in korean health care system. Only concerted efforts from health care policy makers of government on clinical genetics service and genetic counseling for establishing adequate reimbursement coverage and professional communities for developing educational program and certification process for professional genetic counselors, are necessary for the delivery of much needed clinical genetic counseling service in Korea.

• The Korean Journal of Applied Statistics
• /
• v.28 no.2
• /
• pp.295-308
• /
• 2015

We have experienced a substantial improvement in and cost-drop for genotyping that enables genetic epidemiological studies with large-scale genetic data. Genome-wide association studies have identified more than ten thousand causal variants. Many statistical methods based on linear mixed models have been developed for various goals such as estimating heritability and identifying disease susceptibility locus. Empirical results also repeatedly stress the importance of linear mixed models. Therefore, we review the statistical methods related with to linear mixed models and illustrate the meaning of their estimates.

• Smart Media Journal
• /
• v.2 no.4
• /
• pp.34-40
• /
• 2013

Rapid sequencing of individual genomes with next generation sequencer opens new horizon to biology and personalized medicine. The analyzed sequences help to check several genomic abnormality, genomic expression, epigenomic phenotypes, gene annotation after assembly of their reads. Several trials integrating genomic information and clinical data will assist disease diagnostics and clinical treatments. To have a large step towards individualized medicine, development of smart interface linking specialized sequence data to the public is necessary.

• Management & Information Systems Review
• /
• v.35 no.3
• /
• pp.95-113
• /
• 2016

The study examines the question of what discriminant factors may affect differences between two groups classified by researchers' satisfaction with and continuous use intention of genetic resources(microorganisms). Survey data from researchers who are using microorganisms from a gene bank was used to empirically test. The survey, covering 150 researchers, was conducted from March 26 through April 17 2015. Linear discriminant analysis was used to test the research questions described in the study. Results from the tests show that utilization value and suitability of genetic resources for researchers' R&D activities play key roles in discriminating between the two groups classified by researchers' satisfaction with and continuous use intention of genetic resources, relatively lower and higher groups. The results indicate that useful trait information of and degree in promotion of researches by genetic resources appear to be weak in discriminating between the two groups, and that novelty of genetic resources does not play a crucial role in making a distinction between the two groups. We propose some policy implications based on the results of the study.

• Proceedings of the Korean Vacuum Society Conference
• /
• 2014.02a
• /
• pp.301.2-301.2
• /
• 2014

집적회로의 밀도가 높이기 위해 단일 소자의 크기를 줄이는 과정에서 발생하는 소자의 성능 저하를 줄이기 위해 새로운 구조 및 구성 물질을 변경하는 연구가 활발하게 진행되고 있다. 기존의 평면 구조를 변형한 3차원 구조의 n-channel FinFet는 소자의 구성 물질을 바꾸지 않고도 쇼트 채널효과와 누설전류를 줄일 수 있다. 다양한 구조의 유전 물질을 응용한 n-channel FinFEET은 기존의 n-channel FinFET보다 소자의 크기를 줄일 수 있는 가능성을 제시하고 있다. FinFETs에 관한 많은 연구가 진행되어 왔지만, 유전체 물질을 이용한 n-channel FinFETs의 구조에 대한 연구는 매우 적다. 본 연구는 FinFET의fin channel 영역에 유전 물질을 삽입하여 그 영향을 분석한 연구이다. FinFET의 fin channel 영역에 유전 물질을 삽입하여 평면 구조의 MOSFET에서 fully depletion SOI 구조와 같은 동작을 하도록 만들었다. 유전 물질을 삽입한 FinFET 소자의 전기적 특성을 3차원 TCAD 시뮬레이션을 툴을 이용하여 계산하였다. 유전 물질을 삽입한 n-channel FinFET에서 전자 밀도와 측면 전계의 영향이 기존의 FinFET보다 좋은 특성을 확인하였다. 또한 유전물질을 삽입한 FinFETs은 subthershold swing, 누설전류, 소비전력을 줄여 주었다. 이러한 결과는 n-Channel FinFETs의 성능을 향상시키는데 많은 도움이 될 것이다.

• Journal of the Korean Society of International Agriculture
• /
• v.23 no.5
• /
• pp.560-569
• /
• 2011

In Japan, plant genomics research is mainly leaded by the national research institutes. The various structural studies such as rice genome has allowed researchers to analyze useful traits, and to focus their commercialization. With aims to facilitate structural and functional study in plant genome, NIAS (National Institute of Agrobiological Sciences) constructed Poaceae genome DB and RIKEN (Rikagaku Kenkyusho) built DB for Arabidopsis genome and plant full-length cDNA. NIG (National Institute of Genetics) constructed a national biological resources DB (National Bio Resource Project). This compiling DB provides a variety of genome-related research materials for researchers in the field. Recently, as an effort to resolve global issues of food supply and environmental problems, New Agri-genome Project has been performed aiming to develop an innovative agricultural technologies for the quantity, disease resistance and identifying useful genes related to environmental problems. In addition, in order to improve agricultural productivity in developing countries, JIRCAS assisted technical supports for the plant genome research and developed NERICA rice, which is suitable for African area. Such these approaches are expected to contribute to solving the global issues about food, energy and environment in the world.

• Proceedings of the Optical Society of Korea Conference
• /
• 2003.07a
• /
• pp.242-243
• /
• 2003

최근 유전체와 유전체, 유전체와 금속 물질 경계면에서 일어나는 계면 현상에 대한 연구가 활발히 진행되고 있다. 본 연구에서는 유전체와 유전체 경계면에 형성된 소산파의 크기를 maxwell의 방정식을 이용하여 계산하고, 광학 trap을 이용한 광압 측정법을 사용하여 경계면에서 소산파의 크기를 실험적으로 측정하였다. 광압 측정 장치는 그림 1과 같다. (중략)

• Journal of the East Asian Society of Dietary Life
• /
• v.11 no.4
• /
• pp.247-258
• /
• 2001

This study focused on the recognition and information need for GMO(Genetically Modified Organism). The data were collected from 350 adults living in Daegu and Busan by means of a self-administered questionnaire. Frequencies and chi-square tests were conducted by SPSS Windows. The results of the survey were as follows: (1) the concerns about GMO were high but recognition was low. (2) many respondents were worried about the safety of GMO. (3) many people desired the labelling of GMO, and (4) the need for information about GMO was high and most respondents wanted to be informed about safety of GMO. This study suggests that the consumer education about GMO should be conducted through mass media and consumer protection organizations.