• Journal of Animal Science and Technology
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• v.48 no.3
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• pp.353-360
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• 2006

This study was performed to investigate the effects of artificial stimulation on the increase of the oocyte activation, to evaluate the expression of cyclin B1 protein levels in enucleated mouse oocytes, and to investigate correlation between the oocyte activation and the cyclin B1 protein levels. The oocyte activation was induced by 7% ethanol (EtOH) or 10μg/ml Ca-ionophore with or without 10μg/ml cycloheximide (CH). The activation rate was significantly higher in both single (p<0.05) and combined (p<0.01) stimulated groups compared to control group. The cyclin B1 protein level was significantly reduced in both stimulated groups (p<0.05), except for EtOH+CH treatment group. The expression of cyclin B1 protein showed a higher negative correlation with activation rate in EtOH+CH (r=0.61, p<0.05) and Ca+CH (r=0.86, p<0.01) stimulation groups, but not in a both single stimulation groups. Taken together, it can be suggested that single (EtOH and Ca- ionophore) and combined (EtOH+CH and Ca+CH) stimulation increases the oocyte activation, especially combined stimulation, because it induces the degradation of cyclin B1 protein after artificial stimulation treatments in mouse oocytes.

• Applied Chemistry for Engineering
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• v.27 no.5
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• pp.472-477
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• 2016

We studied the effects of anodic oxidation treatments of carbon fibers on interfacial adhesion of the carbon fibers-reinforced epoxy matrix composites with various current densities. The surface of treated carbon fibers was characterized by atomic force microscope (AFM), field emission-scanning electron microscope (FE-SEM), Fourier transform infrared spectroscopy (FT-IR), and X-ray photoelectron spectroscopy (XPS). The interlaminar shear strength (ILSS) of the composites was determined by a short beam shear test. This result showed that both the roughness and oxygen group of the carbon fibers surface increased in proportion to the current density. After anodic-oxidation-treated, the ILSS also increased as a function of the current density. In addition, the proportional relationship between ILSS and phenolic hydroxyl group was confirmed. The ILSS of the CF-2.0 sample increased by 4% compared to that of the CF-AS sample, because the anodic oxidation treatment increased the oxygen group and roughness on the carbon fibers surface, which leading to the improvement of the interfacial adhesion of the carbon fibers-reinforced epoxy matrix composites. Among these, the phenolic hydroxyl group which has the proportional relationship with ILSS is found to be the most important factor for improving the interfacial adhesion of the carbon fibers-reinforced epoxy matrix composites.

• Journal of the Korean Institute of Traditional Landscape Architecture
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• v.33 no.3
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• pp.95-102
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• 2015

This study conducted the survey on the resources of traditional villages based on AHP in the subjects with the specialists in Korea and China to seek the resource evaluation standards to apply the preservation and development of traditional villages, and the differences of the importance on the resources among the specialists in both countries. We classified three levels of evaluation items to aim the deductions of the importance and priority in the resources of traditional villages. Upon the analysis results, natural resources were important in the level 1; environmental, historical, facility resources were important in the level 2; and the factors such as air, topography, traditional houses, agricultural landscape, shared community facilities, interchanges between urban and rural areas, family activities, and so on were important in the level 3. The factors that both Korean and Chinese groups evaluated as the most important ones were the same. In terms of overall importance by evaluation items, the factors such as air, water quality, noise, traditional houses, topography, shared community facilities, and so on were rated as relatively important in both Korean and Chinese groups. That is, the traditional villages have the necessity to preserve the cultural resources like their duties, however, it is required to control the natural environment with good quality preferentially. This study results can compare the importance on the resources of traditional village between Korea and China. Moreover, with calculation of the priority and scores for the preservation and management of traditional villages, they are expected to be used as the tool to apply the quantitative data in the evaluation process of traditional village resources in both countries.

• Journal of Dental Rehabilitation and Applied Science
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• v.29 no.4
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• pp.366-376
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• 2013

The purpose of this study is to evaluate the marginal and internal fit of coping made by CAD/CAM using different scanning methods. Zirconia coping was made by each CAD/CAM system followed by intra-oral scanning, model optical scanning and model contact scanning. It was embedded into Epoxy Resin and was cut by buccal to lingual. AMD (Absolute marginal discrepancy), MG (Marginal gap), GA (Gap of axial), GL (Gap of line angle) and GO (Gap of occlusal) of each sample were measured. The result is as followed; 1. The mean value of AMD in Group 1, Group 2, Group 3 are $141.21{\pm}42.94{\mu}m$, $140.63{\pm}31.64{\mu}m$, $109.37{\pm}28.42{\mu}m$. The averages of MG in Group 1, Group 2, Group 3 are $82.52{\pm}43.99{\mu}m$, $90.28{\pm}27.93{\mu}m$, $66.55{\pm}28.77{\mu}m$. Statistically there is no difference in AMD and MG among the three Groups (Anova, P>0.05). 2. GA of Group 2 revealed statistically difference compared with Group 1 and Group 3 (Anova, P<0.05). 3. GL and GO of Group 1 showed statistically significant differences compared with Group 2 and Group 3 (Mann-whitney test (P<0.05). Zirconia copings made by 3 ways of scanning methods have no difference with conventional ceramics in AMD and MG which are known as the most important factors.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.46 no.5
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• pp.57-70
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• 2009

A CAD design drawing based on vector data that is very important art work in industrial fields has been considered to content that the copyright protection is urgently needed. This paper presents a watermarking scheme based on k-means++ for CAD design drawing. One CAD design drawing consists of several layers and each layer consists of various geometric objects such as LINE, POLYLINE, CIRCLE, ARC, 3DFACE and POLYGON. POLYLINE with LINE, 3DFACE and ARC that are fundamental objects make up the majority in CAD design drawing. Therefore, the proposed scheme selects the target object with high distribution among POLYLINE, 3DFACE and ARC objects in CAD design drawing and then selects layers that include the most target object. Then we cluster the target objects in the selected layers by using k-means++ and embed the watermark into the geometric distribution of each group. The geometric distribution is the normalized length distribution in POLYLINE object, the normalized area distribution in 3DFACE object and the angle distribution in ARC object. Experimental results verified that the proposed scheme has the robustness against file format converting, layer attack as well as various geometric editing provided in CAD editing tools.

• Korean Journal of Food Science and Technology
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• v.40 no.2
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• pp.160-165
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• 2008

This study was conducted to analyze sensory profiles of commercial sojues using a standardized sensory evaluation procedure, and to investigate the effects of sensory characteristics and brands on consumer liking for soju. Descriptive analysis and consumer taste testing were conducted for seven commercial sojues. For the descriptive analysis, eight panelists generated and evaluated 12 flavor and one pain-sensation attributes for the soju, and there were significant differences among the soju samples for all the 13 sensory attributes. For the descriptive data, principal component analysis was performed to summarize the sensory characteristics of the sojues. For the consumer testing, 224 soju drinkers (20-29 year-olds) were recruited and randomly divided into two groups; a blind group and a group with the knowledge of brand. While the hedonic ratings obtained from the blind group didn't indicate significant differences among the sojues, the ratings obtained from the brand-informed group showed significant differences. Finally, the individual preferences of the 112 consumers in each group were investigated by preference mapping techniques.

• Proceedings of the Korea Water Resources Association Conference
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• 2018.05a
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• pp.86-86
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• 2018

본 연구는 한국의 도시재생과 스마트 물 관리의 정책 분석을 위하여 도시재생과 스마트 물 관리의 등장 배경, 주요 현안 및 연계성을 모색하고 도시재생방안으로서 스마트 물 관리체계의 가능성을 검토하는 것을 목적으로 한다. 1950년대의 도시재건(Urban Reconstruction)과 1970~80년대의 도시재개발(Urban Renewal, Urban Redevelopment) 등의 정비 사업은 물리적 환경정비에 초점을 맞추었다. 그러나 1990년대 환경문제가 세계적 이슈로 등장하면서 교외지역 난개발 문제에 대한 대응책이 필요하게 되었고 도시의 물리 환경적, 산업 경제적, 사회 문화적 측면을 부흥시키는 도시재생 접근법이 출현하였다. 한국 정부는 2017년부터 시작한 '도시재생 뉴딜사업'의 일환으로 스마트 기술을 적용한 도시재생사업을 통해 스마트도시 선도국가 도약과 세계적 흐름에 부합하는 도시성장을 기대하고 있다. 1980년대 초 등장한 스마트 기술은 2000년대 들어와 스마트 도시, 스마트 인프라, 스마트 그리드 등의 분야로 확대, 진보하였다. 물 분야의 스마트 기술은 2009년 스마트워터그리드 이니셔티브(Smart Water Grid Initiative)의 발족과 함께 IBM, CISCO, Intel 등의 IT 기반 물 관리 워킹그룹 형성, Suez, Veolia, Siemens 등 수처리 기업의 스마트워터그리드 분야 진출 모색과 함께 발전하기 시작하였다. 이후 2012년 유엔 스마트 물 관리 포커스 그룹(ITU-T SG 5)의 스마트 물 관리 표준화 연구가 착수되었고 한국은 국토교통부 건설교통기술 연구 개발사업 중 하나로 스마트 물 관리 장기 연구 사업을 시작하였다. 스마트 물 관리는 수자원 및 상하수도 관리의 효율성 제고를 위하여 스마트 미터, 센서, 디지털지도제작 등 ICT를 이용한 차세대 물 관리시스템이라고 정의할 수 있다. 구체적인 대상 분야를 고려한다면 하천수, 우수, 지하수, 하폐수처리수, 해수담수 등 다양한 수자원의 관리, 물의 생산과 수송, 사용한 물의 처리 및 재이용 등 물 관리 전 분야를 포함한다. 그러나 스마트 물 관리의 용어와 개념을 처음으로 도입한 미국 등 선진국과 관련기업들은 스마트 물 관리를 '스마트 워터 미터, 센서, 첨단 모델링, 수문 지도제작, 스마트 관개농업, 자동화 로봇 등 다양한 기술을 통합적으로 운영하는 지능적인 수자원 관리를 위한 정보네트워크'로 정의한다. 일찍이 도시재생으로의 패러다임 전환을 실시한 영국 및 일본과 달리 한국의 도시재생은 개념, 구성요소, 범위, 사업방식 등의 여러 가지 측면에서 아직 형성단계에 있다. 또한 한국의 스마트 물 관리 논의는 개념정립 측면에서 심층적 논의가 거의 부재하였다. 기존의 논의들은 수자원 혹은 상하수도서비스 분야에서의 연구결과와 기술개발성과를 기계적으로 적용하고 확대하는 측면만을 부각시켰다. 그러나 이와 같은 스마트 물 관리에 대한 논의는 정보통신기술과 물 관리 서비스를 단편적으로 연결하고 적용범위를 제한할 수도 있다는 점에서 한계성이 있다. 본 연구는 국내외 문헌검토를 바탕으로 한국의 도시재생과 스마트 물 관리의 정책을 분석하고 지금까지 별개로 간주된 두 개념의 장점을 융합하여 향후 지속가능한 도시개발 사업으로서의 가능성을 검토하고자 한다.

• The Korean Journal of Archival Studies
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• no.13
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• pp.41-90
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• 2006

It's needed for the archivists to design a flexible and stable ERMS(Electronic Records Management System) which can ingest and store records through a consistent way and let users search and use records easily what they want. The basis of the design for ERMS are the conceptual composition and the logical and physical structure of the records when they are stored and managed in the ERMS. This paper explains the process of defining components and designing structure of electronic records using 3-layered approaches which consist of conceptual, logical and physical layer and shows advantages of this approaches. After benchmarking the information models of OAIS which is a reference model for the long-term preservation of digital information objects, this paper applies the model of AIP to a record as a 'Record AIP' and discusses the composition and structure of it. It's a critical task to identify mandatory or optional metadata groups which consists of the 'Record AIP's in the conceptual layer. This paper emphases that the metadata group related to services for the record information to users is required as a result of benchmarking OAIS information models. Various issues about the structure of 'Record AIP's are discussed according to the kind of preservation strategy such as migration or emulation and whether the encapsulation of records is required or not in the logical layer.

• The Korean journal of helicobacter and upper gastrointestinal research
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• v.18 no.4
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• pp.277-279
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• 2018

전 세계적으로 Helicobacter pylori의 항생제 내성률은 지속적으로 증가하고 있으며, 기존의 제균 치료에 실패한 H. pylori 감염 환자들에 대한 효과적인 구제요법(rescue therapy)의 필요성 역시 증가하고 있다. 이 연구는 두 개 기관, 공개, 평행 그룹, 무작위 배정 연구로서 불응성 H. pylori 감염 환자들의 구제요법으로 유전자형 내성을 기반한 치료(genotype resistance-guided therapy)와 경험적 치료(empirical therapy) 중 어느 것이 보다 효과적인지를 비교하고자 하였다. 2012년 10월부터 2017년 9월까지 20세 이상의 불응성 H. pylori 감염 환자들을 대상으로 하였으며, 불응성 H. pylori 감염은 과거 두 종류 이상의 H. pylori 제균 치료를 받았음에도 불구하고 H. pylori 제균에 실패한 환자들로 정의하였다. 이들에게서 한 군은 14일간의 유전자형 내성을 기반한 순차 치료(n=21 in trial 1, n=205 in trial 2)를, 다른 한 군은 환자들의 과거 제균 치료 종류를 감안한 14일간의 경험적 순차 치료(n=20 in trial 1, n=205 in trial 2)를 시행하였다. 순차 치료법은 첫 7일은 esomeprazole 40 mg과 amoxicillin 1 g을 하루 두 번 복용한 다음, 나머지 7일은 esomeprazole 40 mg과 metronidazole 500 mg, 그리고 1) levofloxacin 250 mg 또는 2) clarithromycin 500 mg 또는 3) tetracycline 500 mg을 하루 두 번 복용하는 것으로 구성하였다. 23S ribosomal RNA (rRNA)나 gyrase A에 대한 내성 관련 돌연변이 여부는 direct sequencing을 통한 중합효소연쇄반응(polymerase chain reaction, PCR) 검사를 이용하였고, 제균 성공 여부는 요소호기검사를 통해 확인하였다. 일차 결과 지표는 치료 방법에 따른 제균율로 정하였다. Trial 1에서는 tetracycline 대신 doxycycline 100 mg을 사용하였는데, 제균 성공률이 유전자형 내성을 기반한 치료군에서는 17명(81%), 경험적 치료군에서는 12명(60%)으로 나타났다(P=0.181). 하지만, 다른 순차 치료군들과 비교하였을 때, doxycycline을 포함한 순차 치료군의 제균율이 현저히 낮은 것으로 나타나서(15/26, 57.7%) doxycycline을 포함한 순차 치료법은 종결하기로 하고, trial 2부터는 doxycycline 대신 tetracycline으로 교체하여 연구를 지속하였다. Trial 2의 intention-to-treat (ITT) 분석 결과, 유전자형 내성을 기반한 치료군에서는 160/205명(78%), 경험적 치료군에서는 148/205명(72.2%)으로 두 그룹 간의 통계적인 제균율의 차이는 보여주지 못하였다(P=0.170). 부작용 및 환자 순응도에서도 양 군 간의 의미 있는 차이는 없었다. 따라서, 두 종류 이상 H. pylori 제균 치료에 실패한 환자들이라고 할지라도 기존의 제균 치료력을 바탕으로 적절한 경험적 치료를 시행하는 것은 유전자형 내성을 기반한 치료 정도의 효과는 있으며 접근성, 비용, 환자들의 선호도 등의 여러 가지 부가적인 사항들을 고려할 때, 제균 치료력을 고려한 경험적 치료는 간단한 수준의 유전자형 내성을 기반한 치료의 대안으로 받아들여질 수 있을 것으로 제안하였다.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.38 no.6
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• pp.895-906
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• 2018

The improvement project for school zone in Korea is occurring mostly in kindergartens and elementary schools in which children are mainly active, and is being promoted as part of measures to prevent children's traffic accidents. However, since the study on the essential installation facilities and proper level of safety facilities for School zone is lacking, this study relatively evaluated the efficiency of safety facility installation using DEA (Data Envelope Analysis) and suggested improvement plan. We built the facilities and incident data for 28 school zones in Hwaseong City. Six major facilities (Raised intersection, Raised crosswalk, Protective fence, Skid Proof, Speed hump, Speed cameras) that have proven to be effective in the preceding research were analyzed as input factors. As a result of the analysis, only 12 out of 28 showed efficiency and 16 out of efficiency. Effective groups of school zones were found to have fewer installed Protective fences, Skid Proof, and Speed cameras installations than school zones classified as ineffective groups. Protective fences were found to be efficient even if only 47% of the total extension of the school zone was installed, and the number of slip prevention facilities was 8.7 per square km. The number of subjects to be compared is 28, so this study is limited to use as a relative efficiency evaluation index, and it can be grouped into nationwide units and efficiency evaluation can be done for each group.