• Journal of Service Research and Studies
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• v.14 no.2
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• pp.48-68
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• 2024

Due to the global pandemic aftermath of the coronavirus, the importance of health care is being emphasized more socially. Due to the influence of these changes, domestic pharmaceutical companies have introduced regular drug delivery services, that is, drug and health functional food subscription services. Currently, this market is continuously growing. However, these regular services are causing new environmental problems in which the number of waste drugs increases due to the presence of unused drugs. Therefore, this study proposes a service that not only promotes health management through regular medication adherence to reduce the amount of pharmaceutical waste but also aims to improve awareness and practices regarding proper medication disposal. As a preliminary survey for service design, a preliminary survey was conducted on 51 adults to confirm their perception of drug use habits and waste drug collection. Based on the Honey Comb model, a guideline for service design was created, and a prototype was produced by specifying the service using the preliminary survey results and service design methodology. In order to verify the effectiveness of the prototype, a first user task survey was conducted to identify the problems of the prototype, and after improving this, a second usability test was conducted on 49 adults to confirm the versatility of the service. Usability verification was conducted using SPSS Mac version 29.0. For the evaluation results of the questionnaire, Spearmann Correlation Analysis was conducted to confirm the relationship between frequency analysis and evaluation items. This study presents specific solutions to the problem of waste drugs due to the spread of drug subscription services.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2000.04a
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• pp.20-25
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• 2000

아세트아미노펜(파라세타몰)은 p-aminophenol 유도체로서 (그림 1) 두통, 치통, 신경통 등의 통증에 널리 사용되는 해열진통제인데 아스피린과 같은 정도의 해열 진통 효과를 나타내며, 이것은 중추신경계의 체온조절 중추에 작용하여 피부혈관을 확장함으로써 열의 확산을 증가시키는 해열작용과 시상 및 대뇌피질에의 통각역치를 높여 진통작용을 하는 것으로 추정 된다. 아세트아미노펜은 백색의 결정 또는 결성성 가루로 물에 조금 녹고 메탄올 또는 에탄올에 잘 녹으며 수산화나트륨 시액에 녹고 에텔에는 매우 녹기 어렵다 (표1). 대한약전에서는 정제가, 미국약전에는 캅셀제, 좌제, 경구현탁액제, 발포성 건조시럽, 정제 등이 수재되어 있고, 세계 각국에서 OTC 제품으로 1정당 160mg의 츄잉정까지 판매되고 있다. 그러나, 시판되고 있는 정제등은 붕해되어 용출되는데 오랜시간이 소요되어 대한약전에는 약 30분간에 80%이상의 용출기준이 설정되어 있으며, 독특한 쓴맛 때문에 microencapsulation 한 제피세립을 사용하고 있으나 역시 1 정당 300mg 이상의 확산정이나 속용정은 존재하지 않는다. 이것을 개선하기 위하여 붕해속도가 빠르고 특히 진통효과가 빠르며 물없이 구강내에서 간편히 녹여 복용하거나 또는 씹어서 또는 물과 함께 복용할 수 도 있는 $\ulcorner$알카펜$\lrcorner$ 속용정을 개발하게 되었다 (그림2).

• Radiation Oncology Journal
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• v.13 no.4
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• pp.321-330
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• 1995

Purpose : To evaluate whether the early pulmonary irradiation can prevent or decrease the pulmonary damage and contribute to improve ultimate survival in paraquat lung. Materials and Methods : From Jun. 1987 to Aug. 1993, thirty patients with paraquat poisoning were evaluated. Fourteen of these patients were received pulmonary irradiation(RT). All of the patients were managed with aggressive supportive treatment such as gastric lavage, forced diuresis, antioxidant agents and antifibrosis agents. Ingested amounts of paraquat were estimated into three groups(A : minimal 50cc). Pulmonary irradiation was started within 24 hours after admission(from day 1 to day 11 after ingestion of paraquat). Both whole lungs were irradiated with AP/PA parallel opposing fields using Co-60 teletherapy machine. A total of 10Gy(2Gy/fr. x 5days) was delivered without correction of lung density. Results : In group A, all patients were alive regardless of pulmonary irradiation and in group C, all of the patients were died due to multi-organ failure, especially pulmonary fibrosis regardless of pulmonary irradiation. However, in group B, six of 7 patients($86{\%}$) with no RT were died due to respiratory failure, but 4 of 8 patients with RT were alive and 4 of 5 patients who were received pulmonary irradiation within 4 days after ingestion of paraquat were all alive though radiological pulmonary change. One patient who refused RT after 2Gy died due to pulmonary fibrosis. All 3 patients who were received pulmonary irradiation after 4 days after ingestion were died due to pulmonary fibrosis in spite of recovery from renal and hepatic toxicity Conclusion : It is difficult to find out the effect of pulmonary irradiation on the course of the paraquat lung because the precise plasma and urine paraquat concentration were not available between control and irradiation groups. But early pulmonary irradiation within 4 days after paraquat poisoning with aggresive supportive treatment appears to decrease Pulmonary toxicity and contribute survival in patients with mouthful ingestion of paraquat who are destined to have reversible renal and hepatic damage but irreversible pulmonary toxicity.

• 보건세계
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• v.46 no.8 s.516
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• pp.28-29
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• 1999

최근 한국보건사회연구원이 국민의 의약품 사용실태를 조사한 결과에 의하면 1천명중 33명이 매일 항생제를 복용한다. 이는 OECD 회원국가의 평균치 21명보다 월등히 높은 비율로, 약물남용이 우려할 만한 수준임을 보여준다. 이 조사는 또 97년도 의료보험 환자중 병$\cdot$의원에서 58.9$\%$가 항생제를 처방받았다고 밝혔다. 폐렴구균의 70$\~$80$\%$가 항생제 남용으로 페니실린에 내성을 보였는데 이는 아시아 최고수준이다. 약물남용은 항생제 뿐 아니다. 많은 사람들이 의사처방 없이 자가처방으로 약을 구입하며, 자가처방의 절반은 감기약을 구입하는데 이 경우 부적절한 처방이 문제된다. 더구나 감기약은 1가지만으로도 남용할 경우 부작용이 많은데 `판피린과 콘택 600을 주세요` 라는 식으로 물약과 알약을 동시에 주문한다. 이와 같은 약의 중복사용은 약물의 남용효과를 더욱 크게 한다.

• Journal of Aquaculture
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• v.11 no.1
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• pp.11-17
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• 1998

Variations of hepatocyte in the larval liver of grouper, Epinephelus akaara wre examined to understand the effect of starvation during the first feeding period, 3 to 5 days after hatching. Total length of the fed larvae increased from the 5th day after hatching, although no significant difference between the fed and starved larvae was found untill the 4th day after hatching. Survival rate of the starved larvae decreased from the 4th day after hatching, and almost all of the larvae died by the 5th day after hatching. Nuclear size of hepatocyte in the starved larvae starterd to decrease from the 4th day after hatching. The sizes by 4th and 5th days after hatching in the starved larvae were 1.4 to 1.9 times smaller than those in the fed ones. Hepatocytes in the starved larvae showed irregular morphology in which the nuclei were irregularly shrunk and highly compacted from the 4th day, while hepatocyte nuclei in the fed ones maintained their uniform features during the whole experimental period. These results implied that the initial larval food should be supplied at least within the 4th day after hatching. Also, it suggested that the size of hepatocyte nucleus might be and indicator of starvation for wild and cultured grouper larvae.

• Journal of the Korean Society of Food Science and Nutrition
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• v.17 no.4
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• pp.290-304
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• 1988

To evaluate the food habits of middle school students a survey was made by the method of questionaire on 820 middle school students consisted of 370 boys and 450 girls in Taegu city area. The results obtained are summarized as follows; Cookies, fruits, fruit juice and ice cream are their favorite eatings between meals in the decreasing order, And the eatings between meals are more frequent In girls and in the students from financially better homes and from the parents of higher education. More than half of the students have regular or irregular intake of additional vitamin tablets while about 22 percents of them skip their breakfast almost everyday. About 24% of the students hardly pay attention to the relationship between their nutritional condition and their meals. More than seventy percents of the students are taking the instant foods as one of their favorite dishes. The food intake score showed large variation($0{\sim}14$). In general the girls marked higher score than the boys. The students from financially better homes and the students from the parents of higher education marked higher scores. From the 5 scale preference test it was shown that fruits the most favored eatings of the students while the fish and crab scored the lowest mark.

• Proceedings of the Korea Information Processing Society Conference
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• 2020.11a
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• pp.889-892
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• 2020

현재 식품의약품안전처에서 공공데이터 포털에 제공하는 정보에 의하면 국내에는 20,000종 이상의 약이 유통되고 있다. 식약처와 여러 제약회사에서 기본적인 약 정보를 제공하고는 있지만 정확한 처방전이나 설명서가 없는 경우에 무분별한 약 복용의 위험성을 안고 있다. 일부 약 검색을 지원하는 사이트가 있으나 세부 사항을 사용자가 일일이 선택하고 입력해야 정확한 정보를 얻을 수 있다. 본 논문에서는 사용자의 스마트폰을 이용하여 알약을 촬영하면 해당 약을 인식하고 상세 정보를 알려주는 딥러닝 모델을 설계하였다. CNN 신경망을 사용하여 약의 모양, 색상, 마크, 분할선 등을 기준으로 분류하고 인식된 약의 세부 정보는 공공데이터로부터 받아온다.

• Journal of the Korean Society of Radiology
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• v.10 no.1
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• pp.29-37
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• 2016

This study aims to improve the satisfaction level of the patient who undergoes CT contrast examination by developing and applying pretreatment process system, which not only can reduce the side effects caused by the test but also can help carry out the test smoothly. The subjects were 214 patients who booked CT contrast examination from January 2014 to February 2014 but could not carry out their test on schedule. We analyzed the reasons for the delay and conducted follow-up survey on them. We analyzed the usefulness of pretreatment process system by contemplating and developing pretreatment process system and applying it to the patients for whom follow-up survey was conducted from January 2015 to February 2015. The number of outpatients who came to the hospital form January to February 2014 was 2,846 and the number of patients who could not undergo the test was 214, accounting for 7.52% of the total. The specific reason for the delay includes 214 cases of unknown creatinine 98 with 120 minutes of average delay time, 40 cases of creatinine over 1.3(19%) with 30minutes of average delay time, 34 cases of past contrast media side effect 6% with 40 minutes of average delay time and 25 cases of lack of pretreatment such as fasting, etc. 11% with 120minutes of average delay time. The number of CT scan has been increasing ever since the development of CT and the frequency of using the contrast media is expected to increase. If we can employ pretreatment process system in order to effectively control the side effect of contrast media and help the CT contrast examination to be smoothly conducted on schedule, I'm sure we could improve the quality of our medical service and increase our patients' satisfaction who come to our CT scan room.

• 보건세계
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• v.40 no.11 s.447
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• pp.15-17
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• 1993

결핵의 성공적인 치료는 적절한 약제의 사용에 달려 있다. 치료실패의 주요 원인은 불규칙한 약제복용이나 조기중단 그리고 부적절한 치료처방이지만 약제의 부작용으로 인하여 성공적인 치료에 지장을 일으키기도 한다. 결핵 치료에서는 최소한 2가지 이상의 약을 동시에 사용 하므로 부작용 발생시 그것이 어떤 약제와 관련된 것인지를 명확히 밝혀내어 적절히 처리할 수 있어야 한다. 물론 그러기 위해서는 사용하는 약제들의 부작용을 정확히 알아야만 할 것이다. 먼저 약제의 부작용에는 어떠한 종류들이 있는지 살펴보고, 그 다음에는 각각의 결핵약제에서 흔히 접하는 부작용들과 그에 대한 처리방법을 알아보도록 한다.

• RED RIBBON
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• s.69
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• pp.6-7
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• 2006

임신은 HIV의 치료를 연기하는 이유가 되지 않으나 HIV감염 임신 여성은 임신 중, 진통 중, 분만 시, 모유 수유 시 어느 시기라도 바이러스를 태아에 전파할 수 있다. 만약 예방약을 복용하지 않고 모유수유를 한다면 아이에게 감염될 기회는 20-45%가 될 것이다. 모유수유를 하지 않고 치료한다면 전파의 위험성을 2% 이하로 낮출 수 있으며 지도부딘 한 가지 약제의 투여로도 위험성을 반 이상 줄일 수 있다. 그러므로 가임기의 HIV감염인은 임신하기 전부터 감염내과 의사와 산부인과 의사의 긴밀한 협조가 필요하다