• Journal of Society of Preventive Korean Medicine
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• v.19 no.2
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• pp.123-133
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• 2015

The new formular for herbal medicine-safety classification in terms of evidence-based medicine was developed and applied to evaluate various herbal medicines in the previous study. This study is aimed to evaluate the frequently-used herbal medicines inducing toxic metabolites or reactive intermediates(RI), such as Ligusticum wallichii Franch, Angelica sinensis, Glycyrrhizae Radix, Rehmanniae Radix, based on 6 safety grades calculated from human equivalent dose(HED)-based MOS(margin of safety). HED-based MOS can be explained as the ratio of theoretical ALD(approximate lethal dose) of human as $LD_1$(lethal dose of 1%)/ clinical maximum dose as $ED_{99}$(Effective dose of 99%). The herbal medicine showing the ratio less than 1 belongs to Class 1, but the herbal medicine showing the ratio more than 500 belongs to Class 6 with the lowest toxicity. As a result, they were evaluated as class 2 for Angelica sinensis and Glycyrrhizae Radix, class 3 for Ligusticum wallichii Franch and Rehmanniae Radix. These resultant grades for 4 herbal medicines were lower than the grade expected under consideration that these herbal medicines are used very frequently in oriental clinics. These low grades would be due to their ingredients which is biotransformed to toxic metabolites.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.20 no.2
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• pp.131-144
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• 2010

IT developed countries since the late 1980s are used to develop IT security evaluation criteria to ensure safety and reliability of information protection products. Currently a variety of products used for the evaluation based on CC and it takes a long period of product evaluation is required to reduce the developers and users. In this paper refer to the published standard evaluation schedule for the EAL4 calculation model offers a trial period. In addition, based on this commitment by adjusting the number of evaluaters to evaluate the applicant in the evaluation period to minimize the position offers.

• Journal of the Korea institute for structural maintenance and inspection
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• v.18 no.2
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• pp.108-116
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• 2014

The proper stress history measurement should be conducted in order to examine the accurate cause of fatigue cracks or the fatigue safety in the steel bridge. Only one strain gauge is generally installed in the field for the stress history examination because of the field circumstances, economic feasibility, workability, and so on. However, this method may not consider the actual size of the specific structure, the gauge length, and the affect of stress concentration in the welded joint. In addition, it is difficult to apply for the stress analysis. Therefore, this study suggests improvements that are a great number of gauge installations, the gauge location adjustment, and the use of the minimum length gauge. It is drived the correlative equation of strain for the distance between the welding toe and the strain gauge installation, and compare correlative equation with equation of IIW. Also, this study could estimate the remaining life and fatigue damage of bridge in service by selecting the suitable stress category. In conclusion, it is possible to understand the member which is high in the fatigue cracks, and the quantitative relations between the welding toe and the strain gauge installation distances. The proposed approach in this study can make an more accurate fatigue damage and a remaining life prediction so that the improved method should be applied in measuring the strain of bridges from now on.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.8
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• pp.604-609
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• 2019

A variety of complaints about road signs have occurred for various reasons, such as new road facilities, new road signs such as road name signs, and an increase in nearby important facilities. In addition, there are many road signs that are in violation of road sign regulations. The basic principles of road signs, the connectivity of guide names, the location suitability, and a consistent road sign guidance system have not implemented. To solve these problems, various errors were investigated on major road signs on eight national highways, including direction signs, distance signs, boundary signs, and route signs. In addition, we classified the errors on road signs by grade to give them maintenance priority. We also analyzed the error status of signs for each route and grade. Based on the data, the problems of the road signs were derived, and an improvement plan is discussed. Based on this research, more systematic installation and management of road signs through cooperation between the government and local governments could increase the efficiency of road signs, as well as provide safer and more convenient road sign guidance systems for road users.

• Journal of Korean Society of Disaster and Security
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• v.14 no.4
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• pp.69-80
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• 2021

This study tried to suggest improvement measures by discovering problems or matters requiring improvement among the annual regional safety evaluation systems. Briefly introducing the structure and contents of the study, which is the introduction, describes the regional safety evaluation method newly applied by the Ministry of Public Administration and Security in 2020. Utilization plans were also introduced according to the local safety level that was finally evaluated by the local government. In this paper, various views of previous researchers related to regional safety are summarized and described. In addition, problems were drawn in the composition of the index of local safety, the method of calculating the index, and the application of the current index. Next, the problems of specific regional safety evaluation indicators were analyzed and solutions were presented. First, "Number of semi-basement households" is replaced with "Number of households receiving basic livelihood" of 「Social Vulnerability Index」 in the field of disaster risk factors is replaced with "the number of households receiving basic livelihood". In addition, the "Vinyl House Area" is evaluated by replacing "the number of households living in a Vinyl House, the number of container households, and the number of households in Jjok-bang villages" with data. Second, in the management and evaluation of habitual drought disaster areas, local governments with a water supply rate of 95% or higher in Counties, Cities, and Districts are treated as "missing". This is because drought disasters rarely occur in the metropolitan area and local governments that have undergone urbanization. Third, the activities of safety sheriffs, safety monitor volunteers, and disaster safety silver monitoring groups along with the local autonomous prevention foundation are added to the evaluation of the evaluation index of 「Regional Autonomous Prevention Foundation Activation」 in the field of response to disaster prevention measures. However, since the name of the local autonomous disaster prevention organization may be different for each local government, if it is an autonomous disaster prevention organization organized and active for disaster prevention, it would be appropriate to evaluate the results by summing up all of its activities. Fourth, among the Scorecard evaluation items, which is a safe city evaluation tool used by the United Nations Office for Disaster Risk Reduction(UNDRR), the item "preservation of natural buffers to strengthen the protection functions provided by natural ecosystems" is borrowed, which is closely related to natural disasters. The Scorecard evaluation is an assessment index that focuses on improving the disaster resilience of local governments while carrying out the campaign "Creating cities resilient to climate crises and disasters" emphasized by UNDRR. Finally, the names of "regional safety level" and "local safety index" are similar, so the term of local safety level is changed to "natural disaster safety level" or "natural calamity safety level". This is because only the general public can distinguish the local safety level from the local safety index.

• Korean Journal of Construction Engineering and Management
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• v.10 no.1
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• pp.114-125
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• 2009

In this study, a design value analysis technique that considered stochastic LCC and stochastic performance evaluation was proposed, and by introducing the concept of reliability analysis, a decision making that secured reliability was supported. The results of this study, which was carried out according to the above objectives and methods, are summarized as follows: 1) The design value analysis procedures and value state function, improved in order to carry out a reliable analysis when evaluating alternate proposals that were extracted after the function definition was complete, were formalized, and in order to secure consistency and efficiency for value evaluation procedures, an evaluation index scheme was proposed; 2) Database collection and analysis were done for a bridge's LCC analysis. As for the collection scope of data, literature of previous research done on a bridge's LCC analysis was used as the basis for analysis, and for securing reliability regarding analysis results and dealing with uncertainty of collected data, the MCS technique was applied; 3) Weights and evaluation ranks for performance evaluation of each of the alternate proposals, as well as LCC analysis model, analysis period, discount rate, user expense, safety inspection and safety diagnosis expense conditions for LCC analysis were proposed. Lastly, a feasibility study was done and conclusion was made about "OO grand bridge and connecting road construction work execution design" project centered on value analysis execution case.

• The Journal of Korean Medicine
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• v.35 no.1
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• pp.114-123
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• 2014

Objectives: Evidence-based medicine(EBM) advocates the use of up-to-date "best" scientific evidence from health care research as the basis for making medical decisions. EBM also has been applied to traditional Korean medicine(TKM), especially in the field of safety. Recently, the standard prescription for TKM by Korea Institute of Oriental Medicine was published based on toxic index from various toxicity tests. However, there are some limitations when the results from the study based on EBM are applied in clinics. To overcome these imitations, the term "evidence-based practical medicine" was developed and defined as clinically applicable results from the study based on EBM. And safety classification for TKM was suggested as an example of evidence-based practical medicine. Methods: For safety classification for TKM, the data for $LD_{50}$(50% lethal dose), which was transformed to theoretical $LD_1$(1% lethal dose), was analyzed as one of tools for EMB study and divided by maximum dose used in clinics. Results and Conclusions: As a result, human equivalent dose(HED)-based MOS(margin of safety) for korean traditional medicine was calculated and used for safety classification with 5 categories. These categories would be helpful for oriental medicine clinicians to decide the increase and decrease of dosage according to various factors such as patient's sensitivity, potential toxicity of herbal medicines, clinician's experience for better cure. Thus, this safety classification provides some evidences enough that evidence-based practical medicine should be not the same with EBM and defined differently from EBM.

• Journal of the Korean Institute of Gas
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• v.5 no.3 s.15
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• pp.15-22
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• 2001

Reliability evaluation of welded structures by mechanical testing of weld heat-affected zones (HAZs) has become general practice throughout the world. HAZs of steel welded Joints show a gradient of microstructure from the fusion line to the unaffected base metal. This study is concerned a correlation between the microstructural change and the fracture characteristics in HAZs of both seam and girth welds of API 5L X65 pipeline steel, which is generally used for natural gas transmission pipelines in Korea. The focus in this study is the investigation of macroscopic fracture behavior of the various regions within HAZ. Changes in microstructure and toughness were observed using actual HAZ specimens. To evaluate the macroscopic toughness of actual HAZ, Charpy V-notch impact test and CTOD test were performed.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.4
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• pp.2356-2363
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• 2015

This study deals the optimization design with the simulation based design of a coil spring inserted into the lock nut for preventing the screw thread from loosening at the bolted joint when the high-strength steel bolt with the property class of 10.9 is used and the screw torque of 640 to 800 (Nm) is applied. In this study, structural analysis of assembly composed of bolt, nut and coil spring is carried out to evaluate its safety factors on the basis of the equivalent stress with commercial finite element analysis software. And the design strategy to extract the design improvement from these simulation results is established. An iterative process performed with the proposed design strategy is also proposed for improving the performance of the existing design. At the proposed procedure, the feasible design parameters using response surface method are found, and then these parameters are verified to be optimal or not by comparing with the response values and the simulation results obtained from the feasible parameters.

• The Journal of the Korea Contents Association
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• v.19 no.12
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• pp.452-459
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• 2019

In order for an autonomous vehicle to be commercialized, it is necessary to conduct a safety test for every aspect. Considering the implementation of the autonomous vehicles technologies to the highest level, it is necessary to analyze the possible scenarios in the most complex environment as in the urban area. It should be confirmed whether autonomous vehicles can be operated with conventional traffic signal environment. It is also required to confirm the ability of autonomous vehicles in interacting with other vehicles, and coping with possible accidents on the road. In this study, the evaluation factors of autonomous vehicles in the road environment are selected by referring to the other evaluation protocols like ADAS. Study result would be reflected in establishing the autonomous vehicle evaluation method for different test environment along with various technology implementation level.