• Journal of Nutrition and Health
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• v.38 no.7
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• pp.495-502
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• 2005

This study was performed to investigate effects of dietary folic acid supplementation on plasma homocysteine levels, thiobarbituric acid reactive substance s (TBARS) level s and liver SAM/SAH ratio in hyperhomocysteinaemia-induced pregnant rats. Forty-two female Sprague-Dawley rats were divided three groups (C: control diet, HFD: $0.3\%$ homocystine and 0 mg folic acid diet, HFS: $0.3\%$ homocystine and 8 mg/kg folic acid diet) according to homocystine and folic acid levels in the diet. They were fed experimental diets for 5 weeks prior to the mating and also during the entire period of pregnancy till gestational day 20. Dietary folic acid supplementation caused a significant decrease in plasma homocysteine levels which had been increased by a homocystine-diet, with a concomitant increase in plasma and liver folate levels. Liver TBARS levels in homocysteine-folic acid-deficient group (HFD) were higher than those in control group. Dietary folic acid supplementation increased hepatic SAM/SAM ratio in homocysteine-folic acid- sopplemetantion group (HFS) when compared to the HFD (p < 0.05). These data suggest that folate depletion and elevated plasma homocysteine may promote oxidative stress in rat livers and influence the remethylation cycle of the homocysteine metabolism detrimentally. In conclusion, dietary folic acid supplementation was found to be effective for lowering plasma homocysteine levels, relieving oxidative stress, and improving the methylation status in the body.

• Journal of KIISE:Information Networking
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• v.27 no.4
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• pp.498-506
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• 2000

네트워크 관리 시스템은 네트워크를 모니터링하고 감독하여 잘 유지하고 활용성을 높이는 것을 목적으로 하는 시스템이다. 네트워크 관리 시스템 자체의 생존성이 보장되지 않으면 네트워크를 안정한 상태로 유지하는 것은 매우 어렵다. 본 논문에서는 네트워크 관리 시스테 자체의 생존성을 높일수 있도록 매니저들간의 세션을 형성하고 SNA를 통해 고장이 발생한 매니저의 관리 작업을 세션 내의 다른 매니저들이 대행해 주도록 하여 네트워크가 항상 관리될수 있도록 하는 방법을 제안하였다. 제안한 방법은 하나의 관리 스테이션에 집중되던 부하를 하위의 매니저들에게 분산시키고 SNMP 메시지를 전송하기 위해 백본을 통과하는 트래픽을 줄일 수 있다. 제안한 방법의 우수성을 보이기 위해 노드의 오류에 관한 생존성 함수를 도출하였고 그에 따른 분석결과를 도시하였다

• 대한예방의학회:학술대회논문집
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• 2005.10a
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• pp.468-468
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• 2005

• 대한예방의학회:학술대회논문집
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• 2002.10a
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• pp.394-395
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• 2002

• Journal of Nutrition and Health
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• v.34 no.4
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• pp.393-400
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• 2001

We examined the relationship between plasma folate and total homocysteine(Hcy) levels and the distribution of plasma folate and Hcy levels from 204 Korean adults(113 men and 91 women aged between 20yr and 69yr). Plasma folate levels were significantly lower in men(12.2nmol/L) than in women(14.6nmol/L) after controlling for smoking and drinking(p<0.05). Plasma Hcy levels were significantly higher in men(13.9$\mu$mol/L) than in women(11.8$\mu$mol/L) after controlling and drinking. Plasma Hcy levels were more more strongly correlated with plasma folate in women(${\gamma}$=-0.321, p<0.05) than in men(${\gamma}$=-0.202, p<0.05), but the difference between men and women was no longer statistically significant controlling for plasma folate concentration. Prevalence of mild homocysteinemia(plama Hcy>15$\mu$mol/L) was greatest among subjects with lowest folate status. These results indicate a strong association between plasma Hcy concentration and folate status and the poor folate status is the strong causative factor of mild homocysteinemia. (Korean J Nutrition 34(4) : 393~400, 2001)

• Proceedings of the Korean Society of Crop Science Conference
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• 2006.04a
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• pp.448-449
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• 2006

• Journal of Nutrition and Health
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• v.31 no.6
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• pp.1006-1013
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• 1998

The present study was conducted to investigate the effect of different levels of ethanol ingestion on 131ate metabolism and plasma homocysteine concentration in Sprague-Dawley male rats receiving 0, 10, 30% of their caloric intake as ethanol for S weeks. Diets containing 10% ethanol had no effect on plasma and red blood cell(rbc) 131a1e. However, in rats fed a 30% ethanol diet, rbc folate increased and plasma 131ate decreased significantly, In the rats maintained first on a 30% ethanol diet for S weeks and then on a control diet for 2 weeks, the levels of plasma and rbc f31ate were normalized by withdrawal of ethanol. Urinary fo1ate excretion increased markedly in rats fed 10% and 30% ethanol diets and decreased to 51% of controls by withdrawal of ethanol. Plasma homocysteine concentration increased significantly in rats fed a 30% ethanol diet. The results suggest that chronic ingestion of ethanol increased urinary 131ate excretion markedly, which may decrease plasma 131ate and deplete liver folate.

• 전기의세계
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• v.39 no.8
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• pp.38-47
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• 1990

아직도 공급전력의 상당부분을 차지하고 있는 화력발전소는 대규모인데다가 아주 복잡한 시스테인데, 이러한 시스템을 다양한 상황변황에 따라 성능을 충분히 발휘하면서 또한 안전하게 운전하기 위해서는 고도의 운전기술이 요구된다. 현재 주야간 수요격차의 확대와 원자력공급비율의 증가등에 의해 화력발전소는 설비의 노후화가 날로 심해져가고 있고 연일 계속되는 기동정지 등 과도한 운용이 행해지고 있으며, 이러한 상황하에서 전력공급의 책무를 다할 수 있는 동시에 출력 조정능력, 안전도, 열관리 경제운전등에 관하여 더욱 성능을 향상시키는 것이 화력발전소의 운전을 담당하는 자의 올바른 사명이라고 할 수 있을 것이다. 이를 위해서는, 운전, 보수, 관리, 설비면에서 종합적인 대책이 필요하다. 운전면에서의 대책으로는 운전기술의 고도화가 중요하며, 이를 성취하는데 있어서는 발전소운전에 관한 지식의 질적, 양적확충과, 판단의 신속성 및 신뢰도의 향상, 그리고 숙련된 오퍼레이터의 기술의 전승등이 중요한 과제라고 보여지는 바, 기대되는 기술의 수준이 높아져 가고 있기 때문에 그러한 과제들을 해결하기 위해서는 교육훈련의 내실화, 운전수칙의 정비등 종래의 대응책에 덧붙여서 새로운 대응책이 요망되는 것이다.

• Environmental Analysis Health and Toxicology
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• v.16 no.1
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• pp.17-20
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• 2001

The alkaline comet assay, employing a single-cell gel electrophoresis(SCGE), is a rapid, simple and sensitive technique for visualizing and measuring DNA damage leading to strand breakage in individual mammalian cells. The protecting effect of pretreatment with vitamin C and cysteine on the DNA damage of gamma ray was investigated in mice splenic lymphocytes. Vitamin C and cysteine were administered orally for five consecutive days before irradiation. Four week old ICR male mice were irradiated wish 3.5Gy of γ-radiation and were sacrificed 3 days later. Spleens were taken for DNA damage examination by Comet assay and the tail moments of DNA single -strand breaks in tole splenic lymphocytes were evaluated. The results show that pretreatment with vitamin C and cysteine were effective in protecting against DNA damage by gamma ray. Administration of antioxidants like vitamin C and cysteine to mice before irradiation was effective in reducing the tail moment of splenic lymphocytes DNA.

• Journal of the Korean Society of Food Science and Nutrition
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• v.35 no.5
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• pp.557-564
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• 2006

This research was planned and executed to evaluate how the composition of Yak-sun (oriental diet therapy) can effect health conditions of people who are suffering from diet-related diseases like obesity and hyper lipidemia by taking Yak-sun in a form of nutritional supplement with our daily meals. We produced Yak-sun tea with $Ky\hat{a}lmy\hat{a}ngja$, Kamguk, $K\hat{u}m\hat{u}nhwa$, Ch'onkung and observed nutritional composition and evaluated how this tea effects on serum lipids and homocystein concentration by clinical practices. With this observation, we found out that this tea has significant effect on increasing of HDL-cholesterol, decreasing of LDL-cholesterol and homocysteine concentration, and we think that scientific and objective evaluation was done on the components of Yak-sun tea prescription. We concluded that we could apply the components not only in a form of tea, but also in other forms of various food. The information we received from this conclusion will be a basic information on how we can apply oriental medicinal resources into other food and will also be a stepping stone for medicinal herbs to step foot in the field of functional food research, which already draws sizable attention world-wide.