• Title/Summary/Keyword: 승인제

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Swelling Behavior of Low Toxic Absorbent Based on Biopolymer (생물고분자로 이루어진 저독성 흡수제의 팽윤거동)

  • Jung, Jin Hee;Kim, Jin;Lee, Ki-Young
    • Polymer(Korea)
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    • v.37 no.4
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    • pp.478-485
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    • 2013
  • In this study, hydrogels with fast swelling and high absorbent properties were prepared using biopolymers approved as a food additive and their swelling properties were characterized. To improve the swelling properties of conventional hydrogels, we formed gas bubbles using a foaming agent in the process of preparing hydrogels and characterized in terms of equilibrium swelling ratio, swelling kinetics and cytotoxicity. In particular, alginate hydrogels observed by a digital microscope have an open-pore channels structure with the sizes of hundreds micrometers. Also, the cell viability of all hydrogels were found to be much higher than that of poly(acrylic acid).

Partial discharge Measurement on 362 kV GIS of Power Plant Switchyard (화력발전소 S/Y 362 kV GIS 부분방전 정밀측정)

  • Han, Ki-Seon;Yoon, Jin-Yul;Han, Sang-Ok
    • Proceedings of the KIEE Conference
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    • 2007.04b
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    • pp.143-145
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    • 2007
  • 화력발전소 S/Y(switchyard)의 362 kV GIS에 대한 부분방전 정밀측정을 수행하였다. 2005년 부터 화력발전소 S/Y GIS의 고장예방을 위해 설치 운전승인 UHF 부분방전 상시감시시스템에서 상당히 큰 부분 방전신호가 지속적으로 감지되었다. 상시감시시스템에서 방전신호의 원인을 부유전극으로 추정하였으며, 이에 해당 사업소에서 감지된 방전신호의 노이즈 여부 및 방전 발생위치 추정을 위한 기술지원을 요청하였다. 이에 따라 전력연구원은 방전신호를 정밀 측정한 후 PRPD(phase resolved partial discharge) 분석을 통해 부유전극이 GIS 내부에 존재함을 확인하였으며, TOA(time of arrival)법에 의해 제 1 발전기 step-up 변압기부터 인근 가스절연모선 사이에 결함이 존재하는 것으로 추정하였다. 전력연구원의 측정결과를 바탕으로 발전소측에서 해당 개소를 분해 점검한 결과 가스절연모선의 중앙도체를 지지하는 supporting insulator 금구류의 접촉불량에 의한 부유전극 결함을 발견하고 보수하였다. 보수후 상시감시시스템에서 방전신호가 검출되지 않음에 따라 방전원인이 제거되었음을 확인하였다.

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Brief Review on the Processes for RNA-Platform Vaccine Production (RNA 플랫폼 백신 제조공정 고찰 연구)

  • Roh, Hyungmin;Oh, Kyeongseok
    • Journal of the Korea Convergence Society
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    • v.12 no.8
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    • pp.179-186
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    • 2021
  • Among the Covid-19 vaccine platforms, mRNA-platform vaccines are summarized qualitatively in this paper. Manufacturing mRNA vaccines consist of serial processes; the preparation process of DNA template, the transcription of mRNA, nanoemulsion process, and the fill and finish unit combined with formulation stages. It is noticeable that major players are collaborated for producing mRNA vaccines. In particular, the nanoemulsion process is recognized to the key process requiring formulated lipid materials to protect modified mRNA until they arrive in intracellular cytosol. It is known that the nanoemulsion process adapts well-designed microfluidic devices. We expect that the nanoemulsion process will stimulate pharmaceutical industries to develop diverse applications.

Efficiacy of CT Colonography in the Detection of Colorectal Polypoid Lesions (대장의 폴립양 병변의 발견에 있어 CT 대장조영술의 유용성)

  • Kim, Yun-Gyeong;Lee, Ji-Eun;Lee, Jeong-Gyeong;Baek, Seung-Yeon;Song, Hyeon-Ju;Jeong, Seong-Ae
    • Journal of Korea Association of Health Promotion
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    • v.4 no.1
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    • pp.49-59
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    • 2006
  • "본 논문은 대한영상의학회지 2005년 제52권 제1호에 실렸던 논문으로 대한영상의학회의 승인을 득하고 본 협회지에 게재함. Purpose: We wished to compare CT colonography with conventional colonoscopy for the detection of colorectal poiypoid lesions, and we wanted to evaluate the role of IV contrast-enhanced CT colonography for the differentiation between benign polypoid lesions and malignant polypoid lesions. Materials and Methods: Thirty-four consecutive patients underwent CT colonography prior to conventional colonoscopy, Precontrast prone-position CT images and post contrast supine position CT images were obtained and the virtual colonoscopic images were reconstructed, Axial, sagittal and presence, size and morphologic features of colorectal polypoid lesions, and thor these findings were compared with the colonoscopic findings. The degree of enhancement of colorecralpolypoid lesions was measured by subtracting the attenuation valves obtained with precontrastand postcontrast CT images for the differentiation of benignity and malignancy of the colorectal polypoid lesions. Results. Among 75 colorectal polypoid lesions identified on conventional colonoscopy, 49neoplasms were found on CT coloaographv, and the overall detection rate was 65,3%.Detection rate of lesions smaller than l0mm was 52.1%(24/46), and the detection rate for lesions equal to or larger than 10mm was 86.2%(25/29), Morphologic features of the sessile type lesions on CT colonography were well correlated with those noted on colonoscopy, but the stalks were not identified in 6 of 13 polyps on CT colonography. There was no statistical correlation between benignity and malignancy and the degree of contrast enhancement on CT colonography, Conclusion CT colonography is a useful modality for the detection of colorectal polypoid lesionsequal to or polyps. However, CT colonography cannot differentiate benignity from malignancy.

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Privacy Model based on RBAC for U-Healthcare Service Environment (u-헬스케어 환경에서 환자의 무결성을 보장하는 RFID 보안 프로토콜)

  • Rhee, Bong-Keun;Jeong, Yoon-Su;Lee, Sang-Ho
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.16 no.3
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    • pp.605-614
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    • 2012
  • Nowadays u-healthcare which is very sensitive to the character of user's information among other ubiquitous computing field is popular in medical field. u-healthcare deals extremely personal information including personal health/medical information so it is exposed to various weaknees and threats in the part of security and privacy. In this paper, RFID based patient's information protecting protocol that prevents to damage the information using his or her mobile unit illegally by others is proposed. The protocol separates the authority of hospital(doctor, nurse, pharmacy) to access to patient's information by level of access authority of hospital which is registered to management server and makes the hospital do the minimum task. Specially, the management server which plays the role of gateway makes access permission key periodically not to be accessed by others about unauthorized information except authorized information and improves patient's certification and management.

Trend Analysis on the Use of E-Government Services in Korea (우리나라 전자정부서비스 이용 실태 추세 분석)

  • Kwon, Hyuk-Sung;Kim, Joon-Han
    • Informatization Policy
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    • v.23 no.3
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    • pp.3-25
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    • 2016
  • The Korean government has done annual fact-finding surveys on the use of e-government since 2007, but put little effort to analyse and draw implications. We analyzed the trend of the use of e-government in Korea using the survey results of 2012~2015. While the awareness and the user uptake of e-government in Korea have increased steadily, the relative portion and frequency of the use stagnates and falls back. Korean citizens still utilize in-person channel more than e-government channels, and the speed of the transfer from the former to the latter is not fast enough. While more than 95% of the Korean people intend to use the e-government as the main channel in the future, their actual rate of use was 43.2%. We suggest following measures to overcome the troubling situation and increase the uptake of e-government services in Korea through: the expansion of mobile e-government services, strengthening of seamless services, elevation of the level of customization, increasing frequency of using the current e-government services, and raise of the awareness level and the improvement of Korean E-Government Portal.

The Development of an Environmental-Friendly Foam Extinguisher Using a Natural Surfactant (천연계면활성제를 이용한 친환경적 포소화약제 개발)

  • Kim, Jeong-Hun;Lee, Jung-Yun;Kim, Hong;Kim, Eung-Sik;Lee, Myoung-Bo;Kim, Dong-Hyun;Jung, Ki-Chang
    • Fire Science and Engineering
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    • v.21 no.1 s.65
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    • pp.69-73
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    • 2007
  • In this research, an environmental-friendly foam extinguisher was newly developed using a natural surfactant as its composition. Two criteria were applied to verify its extinguishing performance and environmental attraction. One is unit 2 model by "Standards of Model Approval and Inspection Technology for Portable Fire Extinguishers" presented in Korea Fire Equipment Inspection Corporation. The other is Terrestrial Plants, Growth Test and Fish, Acute Toxicity Test presented in Korea Institute of Toxicology(Korea Research Institute of Chemical Technology). Test results showed that the extinguishing performance was 5 unit of general fire Class A, the $LC_{50}$ by germination was 75(g/kg) and the $EC_{50}$ by growth was 62(g/kg) through Terrestrial Plants, Growth Test, and also the toxicity was 6658 ppm in Fish, Acute Toxicity Test. The numerical values were highly evaluated than other fire extinguishing agents being commercialized in domestic. The results also showed suitably in basic physical properties and anti-corrosion properties for making use of fire extinguishing agent.

U-Healthcare user's privacy protection protocol with Implantable medical Device of State Information (상태정보에 따른 체내삽입형 장치를 부착한 유-헬스케어 환자의 프라이버시 보호 프로토콜)

  • Jeong, Yoon-Su;Lee, Sang-Ho
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.37 no.4C
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    • pp.297-306
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    • 2012
  • IT technology of U-healthcare system is being grafted onto medical services and the use of U-healthcare system are extending steadily. However, in case of patients using Implantable Medical Device (IMD) in U-healthcare system, patients' privacy protection and safe access to system recently has emerged as a major issue. This paper proposes a patients' privacy protection protocol to prevent any illegal accesses from third parties as state value and action value are synchronized after patients' information virtualization. The proposed protocol can limit the access range of patients' information according to authentication information of hospitals, doctors, nurses, and pharmacies registered in the U-healthcare server. Additionally, this protocol can increase management efficiency for patients' privacy by synchronizing state values and action values only for approved information and, by instituting this process, third parties cannot easily access patients' information.

A Study of the Implication of Clinical Trial Registration Information and its Application to Industry: Focused on 「COVID-19」 Registered in ICTRP (임상 시험등록정보의 산업적 활용과 시사점: ICTRP에 등록된 COVID-19 사례 중심으로)

  • Lee, Hwajung;Kim, Kyungmi
    • Journal of the Society of Disaster Information
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    • v.17 no.4
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    • pp.778-785
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    • 2021
  • Purpose: The study is to analyze the current status of international clinical trial information services related to COVID-19 and to find out the impact of disclosing activities of clinical trial registration on the medical and pharmaceutical industry. Method: To achieve the purpose of the study, this study analyzed the current status of 780 registered clinical trials for COVID-19 during March of 2020 by using regression analysis. Result: The analysis of clinical trial research registration information showed and proved its usefulness for the development of related new drugs, treatments, vaccines, predictive and prognostic diagnostic kits and treatments related to the COVID-19 (Corona 19) in the world. Conclusion: The study concludes and urges all medical and pharmaceutical companies to register their trials on CRIS and recommends utilizing this registered data to develop advanced drug to benefits all patients related to COVID-19.

Development of glufosinate-tolerant GMO detection markers for food safety management (식품안전관리를 위한 제초제 glufosinate 특이적 GM 작물 검출마커 개발)

  • Song, Minji;Qin, Yang;Cho, Younsung;Park, TaeSung;Lim, Myung-Ho
    • Korean Journal of Food Science and Technology
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    • v.52 no.1
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    • pp.40-45
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    • 2020
  • Over 500 genetically modified organisms (GMOs) have been developed since 1996, of which nearly 44% have glufosinate herbicide-tolerant traits. Identification of specific markers that can be used to identify herbicide-tolerant traits is challenging as the DNA sequences of the gene(s) of a trait are highly variable depending on the origin of the gene(s), plant species, and developers. To develop specific PCR marker(s) for the detection of the glufosinate-tolerance trait, DNA sequences of several pat or bar genes were compared and a diverse combination of PCR primer sets were examined using certified reference materials or transgenic plants. Based on both the qualitative and quantitative PCR tests, a primer set specific for pat and non-specific for bar was developed. Additionally, a set of markers that can detect both pat and bar was developed, and the quantitative PCR data indicated that the primer pairs were sensitive enough to detect 0.1% of the mixed seed content rate.