• Title/Summary/Keyword: 스트레스

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Antioxidant properties of brownish natural dyeing agents from medicinal plant (갈색계 천연색소 추출물의 항산화 특성)

  • Kim, Yeon-Soon;Kwon, O-Jun;Suh, Hwa-Jin;Park, Shin
    • Food Science and Preservation
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    • v.23 no.3
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    • pp.387-392
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    • 2016
  • The antioxidant activities of brownish natural dyeing agents, extracted from seven kinds of plants, were tested. Total polyphenol content, DPPH and ABTS radical scavenging activities, and singlet oxygen quenching effect were determined for hot water extracts and floral waters of plants. DPPH and ABTS radical scavenging activites increased with increasing amounts of the extracts from Uncaria gambir R. and Terminalia chebula R. displayed remarkable scavenging effects at concentrations below 0.1 mg/mL, in comparison with the positive control, ascorbic acid. However, antioxidant effects of the floral water, obtained from steam distillation of tested plants, were inefficient at concentration below 0.2 mg/mL. In particular, the natural dyeing agent effectively suppressed singlet oxygen induced by photosensitizer in in vitro assay systems. The concentrations ($IC_{50}$) required to exert 50% of singlet oxygen were 120 and $190{\mu}g/mL$ for hot water extracts from Uncaria gambir R. and Phellinus linteus, respectively. Among all the tested samples, the Uncaria gambir R. and Phellinus linteus extracts contained higher amount of total phenolic contents. The results suggest that naturally occurring dyeing agents are beneficial as natural antioxidants, encouraging further extensive studies.

Protective effect of STAR of STAR series on CCl4 induced acute hepatotoxicity by regulation of reactive oxygen species (활성산소종의 조절을 통한 음료 '별의별간'의 급성간독성 보호효과)

  • Chang, Bo Yoon;Oh, Jun Seok;Han, Ji Hye;Kim, Da Eun;Hong, Jae Heoi;Kim, Sung Yeon
    • Food Science and Preservation
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    • v.23 no.2
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    • pp.275-282
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    • 2016
  • STAR of STAR (SS 01-04) is a series of drinks that consist of various extracts obtained from Coriolus versicolor, Artemisia capillaris Thunb., Hovenia dulcis, Acanthopanax sessiliflorus, Lycium chinense, Citrus reticulata, Saururus chinensis, Pueraria lobata, Pyrus pyrifolia, and Oenanthe javanica. A purpose of this study was to investigate the hepatoprotective effect of SS 01-04. Antioxidant activity of the drinks was evaluated by conducting a hydroxyl radical-scavenging assay. Cytotoxicity and hepatoprotective potential were determined using HepG2 cells in vitro, while protective effects against acute hepatotoxicity was evaluated in vivo. The antioxidant activity of the SS 01-04 at concentration of 100 and 250 mg/mL was similar to that of $50{\mu}M$ vitamin C. tert-Butyl hydroperoxide (tBHP)-induced production of reactive oxygen species (ROS) was blocked by SS 01, 03 and 04 in a dose-dependent manner. Treatment with SS 04 significantly lowered the serum levels of alanine aminotransferase and aspartate aminotransferase in an animal model of carbon tetrachloride $(CCl_4)-induced$ hepatotoxicity (p<0.05). In addition, SS04 increased glutathione level while decreased malondialdehyde level in the liver considerably (p<0.05). It also inhibited the $CCl_4-induced$ increase in the levels of triglyceride and cholesterol in serum and the liver. These findings indicated that SS 01-04 possessed antioxidant activity and protect against ROS. In particular, SS 04 is potentially highly beneficial in treating liver damage as it scavenges reactive free radicals and boosts the endogenous antioxidant system.

The Perceptions and Purchase Intentions of Health Food Consumers (건강기능식품에 대한 인식 및 구매의도 연구)

  • Lee, Jeung-Yun;Chae, Soo-Kyu;Kim, Kyu-Dong
    • Food Science and Preservation
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    • v.18 no.1
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    • pp.103-110
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    • 2011
  • We investigated consumer perceptions of and purchase intentions for health foods. Data were collected from 454 adults over the age of 20 years living in Seoul and Gyeonggi province, from May 10 to June 5, 2010. Those that "hardly ever drink" (41.4%) were most prevalent in terms of drinking activity, whereas 80.8% of respondents did not smoke. Also, those who responded "hardly ever exercise" ranked highest; although 43.8% in fact exercised frequently. Of all respondents, 44.5% admitted to suffering slightly from stress. A total of 59.5% of respondents opined "I am healthy but I do worry about health", and "exercise" topped the list of approved (37.2% of respondents) health care methods. We also found that 83.5% of respondents claimed to have tried health foods, whereas in the case of having no taking experience, 60% had not purchased such foods because, in their view, this was unnecessary. The extent of concerns about health foods scored 3.09, and the level of purchase intentions for health food was high, with a score of 3.40. Therefore, all of government, producers, distributors, and academic researchers must provide consumers with accurate and complete information, and need to collaborate in the development of consumer education programs on health foods. This will enhance consumer interest in such foods, and empower logical choices.

Study on Vessel Traffic Risk Assessment according to Waterway Patterns in a Southwest Offshore Wind Farm (서남해 해상풍력발전단지 내 항로형태에 따른 선박통항 위험도 평가에 관한 연구)

  • Jang, Da-Un;Kim, Deug-Bong;Jeong, Jae-Yong
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.25 no.6
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    • pp.635-641
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    • 2019
  • Domestic southwest offshore wind farms have problems such as the reduction in fishing rights by prohibiting vessel traffic, which delays their development. As such, there is a need to develop offshore windfarms in Europe to permit the passage of vessels and fishing operations in specific offshore windfarm areas. In this study, we used the environmental stress (ES model) and the IALA Waterway Risk Assessment Program (IWRAP) to determine the ratio of risk to the route type (cross pattern, grid pattern) and traffic volume (present, 3 times, 5 times and 10 times) to derive the risk factors of specific vessels for offshore windfarms. As a result, ship operators' risk related to offshore windfarms did not rise in both route types and there was no significant difference in the annual probability of collision in the present traffic volume. In conditions that increased traffic volume by 3 times, 5 times and 10 times, the risk ratio increased as ship operator risk and collision probability increased at the crossing points. Furthermore, when the traffic volume of the ship increased, the risk could be more effectively distributed in the grid route compared to the cross route. The results of this study are expected to apply to the operation type, route operation method, safety measures, etc. in offshore wind farms.

A Review of Research Trends on Trauma in Maritime Police Officers and Police Officers in Korea (해양경찰·경찰 공무원의 외상(trauma)관련 국내 연구 동향)

  • Park, Kyung Ryun
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.26 no.4
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    • pp.327-335
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    • 2020
  • The purpose of this study was to analyze research trends on trauma in maritime police officers and police officers in Korea and suggest future research directions. We collected 57 studies related to trauma in maritime police and police from Korean Citation Index listed journals and analyzed basic information, subjects, research methods, measurements and related variables. The results showed that studies have been conducted sporadically from 2010 and only six out of the 57 studies were conducted for maritime police officers. Police administration (59.6 %) was the most common area of researchers' major, followed by psychology (19.3 %), medicine and nursing (10.5 %), social welfare (8.8 %) and education(1.8 %). Five out of the six maritime police studies were conducted in the police administration field. Most of the studies adopted the quantitative research method (78.9 %). Only three studies adopted the qualitative method, all of which targeted police officers. The IES-R-K was the most used PTSD scale, followed by the PDS and the PCL-5. Trauma-related variables were commonly conducted in the order of traumatic event experience, resilience, stress-coping methods and social support. Finally, the implications of the findings of our study and the suggestions for further research were discussed.

Cutting Propagation of Eleutherococcus senticosus MAXIM (가시오가피의 거목번식방법(揷木繁殖方法))

  • Park, Ho-Ki;Park, Moon-Soo;Kim, Tai-Soo;Choi, In-Leok;Jang, Yeong-Sun;Kim, Gue-Seong
    • Korean Journal of Medicinal Crop Science
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    • v.2 no.2
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    • pp.133-139
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    • 1994
  • Eleutherococcus senticocus MAXIM containing compounds for a cordial and lumbago is a native plant in this country. However it is generally difficult to propagate them by seed. This study was carried out to improve propagation efficacy by cutting method using Eleutherococcus senticosus MAXIM collected Mt. Odae for three years$('90{\sim}'92)$. Rooting was delayed by 3 to 12 days but callus formation and rooting percentage was high by 75%, 30% respectively in the treatment of Rooton-F powder, a chemical for rooting promotion, compared with non-treatment. Rooting percentage and rooting characters were not differenced by treatment for remove rooting inhibition compounds and soil-media mixured by 1:1 of vermiculite and perlite was suitable for elevating rooting ratio. A. chiisanensis and A. sieboldianum were rooted well in any time to be cut, while rooting activity of E. senticosus was different by time to be cut. Rooting ratio of E. senticosus was 26%, 36% and 60% when cutten March 20, July 20 and september 20, respectively.

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Defensive roles of Sdu1, a PPPDE superfamily member with ubiquitin C-terminal hydrolase activity, against thermal stress in Schizosaccharomyces pombe (카르복시 말단 유비퀴틴 가수분해 효소 활성 보유 PPPDE superfamily member인 Schizosaccharomyces pombe Sdu1의 열 스트레스에 대한 방어적 역할)

  • Han, Hee;Heo, Tae Young;Ryu, In Wang;Kim, Kyunghoon;Lim, Chang-Jin
    • Korean Journal of Microbiology
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    • v.51 no.4
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    • pp.319-328
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    • 2015
  • The $sdu1^+$ gene encodes Sdu1, a PPPDE superfamily member of deubiquitinating enzymes (DUBs) in Schizosaccharomyces pombe. Sdu1 was previously shown to contain an actual ubiquitin C-terminal hydrolase (UCH) activity using the recombinant plasmid pYSTP which harbors the $sdu1^+$ gene. This work was designed to assess a thermotolerant role of Sdu1 against high incubation temperatures. In the temperature-shift experiments, the S. pombe cells harboring pYSTP grew much better after the shifts to $37^{\circ}C$ and $42^{\circ}C$, when compared with the vector control cells. After being shifted to $37^{\circ}C$ and $42^{\circ}C$ for 6 h, the S. pombe cells harboring pYSTP contained lower reactive oxygen species (ROS) levels, compared with the vector control cells. The nitric oxide (NO) levels of the S. pombe cells harboring pYSTP were slightly lower than those of the vector control cells in the absence or presence of the temperature shifting. The total glutathione (GSH) levels of the S. pombe cells harboring pYSTP were significantly higher than those of the vector control cells. Total superoxide dismutase (SOD) and GSH peroxidase activities were also higher in the S. pombe cells harboring pYSTP after the temperature shifts than in the vector control cells. In brief, the S. pombe Sdu1 plays a thermotolerant role against high incubation temperature through the down-regulation of ROS and NO and the up-regulation of total GSH content, total SOD and GSH peroxidase activities.

PWM-PFC Step-Up Converter For Novel Loss-Less Snubber (새로운 무손실 스너버에 의한 PWM-PFC 스텝-업 컨버터)

  • Kwak Dong-Kurl;Lee Bong-Seob;Jung Do-Young
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.43 no.1 s.307
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    • pp.45-52
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    • 2006
  • In this paper, authors propose a step-up converter of pulse width modulation (PWM) and power factor correction (PFC) by using a novel loss-less snubber. The proposed converter for a discontinuous conduction mode (DCM) eliminates the complicated circuit control requirement and reduces the size of components. The input current waveform in the proposed converter is got to be a sinusoidal form of discontinuous pulse in proportion to magnitude of ac input voltage under the constant duty cycle switching. Thereupon, the input power factor is nearly unity and the control method is simple. In the general DCM converters, the switching devices are fumed-on with the zero current switching (ZCS), and the switching devices must be switched-off at a maximum reactor current. To achieve a soft switching (ZCS and ZVS) of the switching turn-off, the proposed converter is constructed by using a new loss-less snubber which is operated with a partial resonant circuit. The result is that the switching loss is very low and the efficiency of converter is high. Some simulative results on computer and experimental results are included to confirm the validity of the analytical results.

The Clinical Study On Posttraumatic Stress Disorder Patients due to a Serise of Traffic Accidents;SCL-90-R (교통사고 후 외상성 스트레스 장애 후유증 환자에 대한 고찰;SCL-90-R 중심으로)

  • Ko, Kyoung-Mo;Choi, Sung-Hun;Kim, Jae-Su;Park, Seo-Young;Lee, Yun-Kyu;Lee, Yoon-Kyoung;Lee, Kyung-Min;Lee, Bong-Hyo;Lim, Seong-Chul;Choi, Hong-Sik;Lee, Eun-Kyung;Jung, Tae-Young;Seo, Jung-Chul
    • Journal of Acupuncture Research
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    • v.24 no.6
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    • pp.63-68
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    • 2007
  • Objectives : The purpose of this study was designed to estimate the effects of Oriental medical treatment on posttraumatic stress disorder patient due to a series of traffic accidents by using SCL-90-R. Methods : We studied 20 patients who were admitted to Daegu Haany University Oriental Hospital from October2006 to May 2007. Results : 4 symptoms of SCL-90-R, somatization, obsessive-compulsive, depression and anxiety were significantly different when comparing after-treatment with before-treatment. But, 5 symptoms of SCL-90-R, interpersonal sensitivity, hostility, phobic anxiety, paranoid ideation and psychoticism showed no difference between after-treatment with, before-treatment measurements. The total impact or SCL-90-R was significant comparing after-treatment with before-treatment measurements. Conclusions : We concluded that there was a significant effectof Oriental medical treatment on posttraumatic stress disorder patients caused by a seriesof traffic accident. However, the findings of this study need to be confirmed in more patients with further studies.

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Liriopis Tuber improves stress-induced memorial impairments in rats (구속 스트레스로 유발된 기억 손상에 대한 맥문동(麥門冬)의 신경보호 효능)

  • Kang, Young-Gun;Lee, Tae-Hee
    • The Korea Journal of Herbology
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    • v.21 no.2
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    • pp.63-75
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    • 2006
  • Objectives : We investigated the effects of Liriopis Tuber on the nervous protection. Methods : We measured the reaction behavior with EPM(Elevated Plus Maxe) and MWM(Morris Water Maze) after applying restraint stress to rats. Also, the degrees of AchE generation were measured with immunohistochemical method in the regions of hippocampus, and the degree of TH generation in the regions of VTA and LC, respectively. Results : 1. As the results of measuring how long EPM which reflects anxiety reaction stayed in the open arm, there was the trend which can suppress anxiety reaction in the MMD+stress group(Liriopis Tuber+stress) but no statistical significance. The counting results how many EPM passed between opened and closed arm showed suppression trend against a physical activity in the saline+stress group but there was no statistical significance. 2. According to the result of MWM, the saline+stress group showed the learning retardation which means increased time arriving at goal compared to ti1e normal group at the second and third day of measurement. On the contrary, a learning retardation was significantly decreased in the MMD+stress group. Among the probe trial test a memory loss occurred in the saline+stress group, meanwhile memory ability was notably increased in the saline-stress group. 3. The degree of TH generation was investigated at the VTA and LC respectively after test animals treated with drug. In the saline+stress group, TH-immunoreactive cells were significantly increased, and these stress-induced TH increases were suppressed in the saline+stress group at the VTA region. However, the saline+stress group did not show any significant difference. 4. the degree of AchE generation was investigated at the CA3 of hippocampus. The saline+stress group showed that AchE-immunoreactive cells were significantly decreased. Those stress-induced reductions of AchE cells were meaningfully recovered in the saline+stress group. Although the cells showed recovery trend in the region of CA1 of hippocampus, statistical significance was not observed. Conclusion : The results of our study indicate that Liriopis Tuber can improve spatial memory ability of rats applied a restraint stress. This improvement of the spatial memory ability is considered to have an efficacy of nervous protection that Liriopis Tuber suppresses the generation of AchE in the hippocampus region and enhances the generation of TH in the VTA.

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