• Korean Journal of Clinical Laboratory Science
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• v.52 no.1
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• pp.1-17
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• 2020

Three-dimensional microscopic approaches in histopathology display multiplex properties that present puzzling questions for specimens as related to their comprehensive volumetric information. This information includes spatial distribution of molecules, three-dimensional co-localization, structural formation and whole data set that cannot be determined by two-dimensional section slides due to the inevitable loss of spatial information. Advancement of optical instruments such as two-photon microscopy and high performance objectives with motorized correction collars have narrowed the gap between optical theories and the actual reality of deep tissue imaging. However, the benefits gained by a prolonged working distance, two-photon laser and optimized beam alignment are inevitably diminished because of the light scattering phenomenon that is deeply related to the refractive index mismatch between each cellular component and the surrounding medium. From the first approaches with simple crude refractive index matching techniques to the recent cutting-edge integrated tissue clearing methods, an achievement of transparency without morphological denaturation and eradication of natural and fixation-induced nonspecific autofluorescence out of real signal are key factors to determine the perfection of tissue clearing and the immunofluorescent staining for high contrast images. When performing integrated laboratory workflow of tissue for processing frozen and formalin-fixed tissues, clear lipid-exchanged acrylamide-hybridized rigid imaging/immunostaining/in situ hybridization-compatible tissue hydrogel (CLARITY), an equipment-based tissue clearing method, is compatible with routine procedures in a histopathology laboratory.

• Journal of Korean Society of Forest Science
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• v.104 no.4
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• pp.536-542
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• 2015

This study was examined for the growth response of tree diameter and volume to thinning treatments from different thinning intensities using three long-term thinning trials for Japanese Evergreen Oak (Quercus acuta Thunb.) stands in Wando island, Korea. After thinning in 1999, annual tree growth of diameter and volume was highest in heavy thinned stands for individual tree and this growth pattern of thinning response showed similar tendency to the individual tree growth response in light thinned stands. By increasing diameter growth, the value of H/D ratio (HDR) as an indicator of stem form was properly decreased and improved up to 80%. Although there is significant growth response of basal area in both heavily and lightly thinned stands, the growth potential both of heavily and lightly thinned stands in total stand volume is not likely to reach at the level of unthinned stands because of basal area growth loss associated with both light and heavy thinnings.

• Journal of the Korean Magnetics Society
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• v.22 no.2
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• pp.49-57
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• 2012

From among the NDT (Non-Destructive Testing) methods, the MFL (Magnetic Flux Leakage) PIG (Pipeline Inspection Gauge) is especially suitable for testing pipelines because the pipeline has high magnetic permeability. MFL PIG showed high performance in detecting the metal loss and corrosions. However, MFL PIG is difficult to detect the crack which occured by exterior-interior pressure difference in pipelines and the shape of crack is very long and narrow. Therefore, the new PIG is needed to be researched and developed for detecting the cracks. The CMFL (Circumferential MF) PIG performs magnetic fields circumferentially and can maximize the magnetic flux leakage at the cracks. In this paper, CMFL PIG is designed and the distribution of the magnetic fields is analyzed by using 3 dimensional nonlinear finite element method (FEM). By Simulating and Measuring the magnetic leakage field, it is possible to detect of axial cracks in the pipeline.

• Korean Journal of Food Science and Technology
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• v.47 no.2
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• pp.267-271
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• 2015

This study aimed to determine the optimal freezing temperature for preserving mulberries. Mulberries were frozen at -20, -45, and $-70^{\circ}C$ immediately after harvesting. After 24 h, frozen mulberries were stored at $-20^{\circ}C$ for two months and then thawed at $4^{\circ}C$ and room temperature. Frozen and thawed mulberries did not differ significantly in color and pH from fresh mulberries. However, the content of anthocyanidin and sugar, and the hardness of mulberry significantly decreased after feeze-thawing. Drip loss of the thawed berries increased as the freezing temperature decreased. A comparison among cross-section images of mulberries frozen at different temperatures did not show any significant differences. However, after thawing at $4^{\circ}C$ or room temperature, the total number of aerobic bacteria found in mulberry decreased more than ten times. Consequently, the freezing temperature showed no significant effect on the overall quality of the mulberry.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.3
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• pp.476-482
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• 2019

Regulatory protocols such as the Convention on Climate Change and the regulation of greenhouse gas emissions act as catalysts for the development of high-efficiency energy equipment and the efficient use of energy. Among the fields where energy consumption is high, the electric heating equipment is not efficient. The electric boiler mainly uses a method of circulating water by contacting the heater. When the existing electric boiler is used, the water minerals are contacted with the high-temperature heater to be carbonized and adsorbed, thereby promoting the corrosion of the heater and lowering the efficiency of the heater. For this reason, an electric induction boiler, which has high energy efficiency and is applied to an induction heating system that can uniformly heat the object to be heated rather than conduction or convection heating, is in the limelight. This method induces a boiler pipe And it is recognized as an alternative that can solve the problem that occurs when heating is performed by direct heating. Despite the fact that research on induction heating has been conducted for a relatively long period of time, there have been few studies on the electrothermal technology using induction heating. Therefore, in this paper, to improve the heat efficiency of electric induction boiler, the influence of the cross sectional area, number of windings and winding layers is analyzed by finite element method through parametric study method. The method of finding the design point which maximizes the total loss is proposed by the alternating winding design method which can maximize the heat generation by analyzing copper and iron losses.

• Journal of Korean Tunnelling and Underground Space Association
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• v.23 no.5
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• pp.359-370
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• 2021

Duct slabs, which are used to build ventilation facilities in underground spaces with transverse ventilation system, need to secure fire resistance according to longitudinal and heavy vehicle traffic of tunnels. This study measured the temperature change at the construction joint of the precast fireproof duct slab which integrates fire resistance material and duct slab under the RWS fire scenario. As a result, it was confirmed that if there is no reinforcement of the construction joint, damage will occur in concrete inside the construction joint, leading to damage to the fireproofing layer. On the other hand, when one side of the construction joint was reinforced with fireproofing materials, it showed more than three times the fire resistance performance compared to when there was no reinforcement. At this time, cross-sectional losses of concrete and fireproofing layer were shown in blocks without reinforcement, but no damage was seen in the reinforced blocks.

• Tunnel and Underground Space
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• v.31 no.6
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• pp.520-533
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• 2021

It is necessary to increase the blasting efficiency in order to minimize the economic loss caused when the excavation cross section is reduced due to the stability problem of underground mining development, and for this, a new blasting design is proposed. In this study, the blasting efficiency of the general design in the field, the suggestion designI, which added two columns to production blasting, and the suggestion design II, which added one column to create asymmetry, is compared. Advance rate and fragmentation were selected as the evaluation index of the blasting efficiency. In the case of advance rate, compared to the normal, the suggestionI improved by 6.07% and the suggestionII improved by 4.65%. In the case of fragmentation, based on P80, compared to the normal, the suggestionI reduced about 58% and the suggestionII was about 47%. Accoording to the evaluation index, the suggestion designI shows better blasting efficiency than the suggestion designII. But considering the additional work time and cost required for the suggestion designI due to the insignificant difference in the evaluation index results, the asymmetry V-cut, the suggestion designII, is judged to be a more suitable blasting design for the site.

• Tunnel and Underground Space
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• v.31 no.6
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• pp.469-479
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• 2021

As a material for preventing spalling of concrete, the effectiveness of PP fiber has already been confirmed. However, it is necessary to consider the maximum temperature that occurs during a fire, and to solve the mixing problem and the strength reduction problem that occur depending on the mixing amount. In this study, the fire resistance performance of tunnel segment linings according to the PP fiber content and air volume under the RABT fire scenario was investigated. As a result, no spalling or cross-sectional loss occurred in all test specimens, and when the PP fiber content was small, the maximum temperature was relatively high and the maximum temperature arrival time was also fast. On the other hand, no trend was found for the maximum temperature and arrival time according to the difference in air volume. In the internal temperature distribution results for the PP fiber mixing amount of 0.75, 1.0, 1.5, and 2.0 kg/m³, the results of 0.75 and 1.0 kg/m³ showed similar temperature distribution, and the results of 1.5 and 2.0 kg/m³ were similar. It was confirmed that the internal temperature distribution tends to decrease at the same depth when the amount of PP fiber mixed is large, and it was confirmed that a remarkable difference occurred from the results of 1.0 kg/m³ and 1.5 kg/m³ of PP fiber mixed amounts.

• Tunnel and Underground Space
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• v.32 no.6
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• pp.363-372
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• 2022

Precast concrete is an effective method to increase the construction quality and construction speed by optimizing and making the manufacturing conditions similar. In order to more effectively produce a fireproof material-integrated precast duct slab, the purpose of this study was to determine whether the fire resistance performance of the fireproof layer is maintained when a method of increasing the curing rate using a hardening accelerator is used. As a result of performing a fire resistance performance test on specimens classified according to whether or not the hardening accelerator was included, increase of temperature inside the specimen was high in the specimens using the hardening accelerator, and the section loss of the fireproof layer occurred locally on the surface exposed to fire heating. In conclusion, it is judged that the fireproof layer in the case where the strength at 3th day of age is gained within 1 day curing age using a hardening accelerator does not guarantee sufficient fire resistance performance in the conditions used in this study.

• Geophysics and Geophysical Exploration
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• v.25 no.2
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• pp.59-70
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• 2022

Recent studies demonstrate that machine learning has expanded in the field of seismic interpretation. Many convolutional neural networks have been developed for seismic sequence identification, which is important for seismic interpretation. However, expense and time limitations indicate that there is insufficient data available to provide a sufficient dataset to train supervised machine learning programs to identify seismic sequences. In this study, patch division and data augmentation are applied to mitigate this lack of data. Furthermore, to obtain spatial information that could be lost during patch division, an artificial channel is added to the original data to indicate depth. Seismic sequence identification is performed using a U-Net network and the Netherlands F3 block dataset from the dGB Open Seismic Repository, which offers datasets for machine learning, and the predicted results are evaluated. The results show that patch-based U-Net seismic sequence identification is improved by data augmentation and the addition of an artificial channel.