• Journal of Life Science
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• v.18 no.1
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• pp.1-8
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• 2008

The purpose of this study was to determine the possible additive effects of endurance exercise training (EXER) and selenium (SELE) on the improvements of glucose and lactate transport capacities in diabetic Goto-kakizaki rats. Animals either remained sedentary control (SED) or performed EXER or received SELE [$5{\mu}mol$ kg body wt (-1) day (-1)], or underwent both EXER and SELE (COMBI), which lasted for 6 wk. Compared with sedentary control, EXER alone or the SELE alone group, or the combined treatment group had significant reduction in glucose response measured at 90 min and 120 min during an intraperitoneal glucose tolerance test (IPGTT) and body weight after 6week treatment. EXER alone, or combined group individually had significantly higher glycogen contents in liver compared with SED or SELE groups. EXER alone increased glycogen content in soleus and plantaris compared with SED, and this parameter was increased to greatest extent in the combined treatment groups compared with SED or SELE groups. EXER alone, SELE alone or COMBI, caused significant decreases in the plasma lactates, serum glucose, insulin, total cholesterol and HOMA-IR along with a significant increase in high-density lipoprotein cholesterol compared with SED. In addition, EXER or COMBI individually had significantly lower serum triacylglycerol compared with SED or SELE. With respect to protein expression related to glucose and lactate transport capacities, EXER alone, SELE alone, or COMBI increased in MCT1 and MCT4 protein level in soleus and plantaris. Furthermore, EXER alone, SELE alone or COMBI caused significant increases in mt MCT1 protein level in soleus and plantaris. The findings of the current study suggest that endurance exercise training and selenium treatment may provide therapeutic values to type II diabetic patients with peripheral insulin resistance and hyperlactatecemia by improving glucose and lactate transport capacities, leading to improvements in plasma lactate, serum glucose, insulin and lipid profiles (TC, TG, HDL).

• Journal of Life Science
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• v.32 no.6
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• pp.455-462
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• 2022

This study examined changes in the body composition of Protaetia brevitarsis larvae fed sulfur and selenium. Among the general chemical components, an increase in protein was observed in the sulfur-fed group, whereas an increase in fatty acid was found in the groups fed selenium and sulfur/selenium. The structural amino acid showed some tendency to be increased compared to the control group, but this was especially true in the sulfur-fed group. The free amino acid were increased in the groups fed selenium and sulfur/selenium, with GABA, Glu, and Pro, in particular, being increased in the group fed sulfur/selenium. Among the essential amino acids, Met, Trp, and Val tended to be increased in selenium and sulfur/selenium groups. Saturated and polyunsaturated fatty acids showed a tendency to increase in the group fed sulfur/selenium, but monounsaturated fatty acid tended to be decreased in the group. In particular, no oleic acid was detected in the sulfur/selenium group, whereas palmitic acid, palmitoleic acid, and linoleic acid were increased. From observations of these body composition changes associated with the feeding of sulfur and selenium, it is estimated that the group fed sulfur/selenium would likely undergo a pronounced change in body composition. Therefore, we suggest that it is possible to manufacture a food that has enhanced functionality by appropriately adjusting the diet of Protaetia brevitarsis larvae.

• Journal of Yeungnam Medical Science
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• v.9 no.1
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• pp.29-43
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• 1992

A case-control study was conducted to investigate the association between the risk of cancer and selenium concentration in blood and toenails. Seventy three patients and two hundreds eighty three controls were, selected at the Yeungnam University Hospital between May and September in 1991. The selected cases were patients who had been hospitalized for stomach or colon cancer at the Depertment of General Surgery. The controls were people who visited to check physical examination at the Automated Mediscreening Center. The selenium concentration in whole blood and toenails were measured by atomic absorption spectrophotometer equipped with graphite furnace atomizer. The following information was ascertained for all cancer patients and controls : sex, age, body mass index, blood pressure, total serum cholesterol, and history of smoking and drinking. The mean selenium concentration in blood and toenail for all cancer patients were $143.6{\pm}10.8{\mu}g/l$ and $1.04{\pm}0.62{\mu}g/g$ and for the controls, $167.0{\pm}14.5{\mu}g/l$ and $1.15{\pm}0.55{\mu}g/g$, respectively. The difference in blood and toenail selenium concentrations of the two cancer sites was not statistically significant. Metastasis did not influence the concentration of selenium in blood and toenails. In the multiple logistic regression analysis, the blood selenium concentration($_aOR$: 0.888, 95% CI : 0.860-0.918), age, BMI and total serum cholesterol were significant variables for risk of cancer, but the selelenium concentration in toenail was not shown to be a significant variable in this regression analysis. The coefficient for blood selenium concentration adjusted for age, sex, diastolic blood pressure, total serum cholesterol, body mass index and smoking was -0.1184(p<0.01). These findings suggest that low selenium concentration is associated with gastrointestinal cancers. Further epidemiologic studies including important variables such as other antioxidant micronutrients will be necessary.

• Journal of Bio-Environment Control
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• v.6 no.4
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• pp.264-269
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• 1997

This study was conducted to evaluate appropriate selenate ion concentration for the production of high functional vegetables. Sodium selenate was treated 0, 2, 4, 6 and 8mg/$\ell$ using herb nutrient solution developed by European R & D Vegetable Center in Belgium. Low level of Na2se04 concentration increased the growth of wormwood, but high selenate concentration decreased the growth. Total chlorophyll content was increased by sodium selenate. The higher selenate ion concentration in the nutrient solution, the more total chlorophyll content was. The vitamin C content in wormwood was high at 2 and 4mg/$\ell$ treatment, showing good growth, at higher concentration, however, the vitamin C content decreased. At 4mg/$\ell$ selenate ion concentration, essential oil content of wormwood was best. But higher selenate ion concentration decreased essential oil content. The uptake of Se by the plant increased with the increase of selenate ion concentration.

• Journal of Nutrition and Health
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• v.37 no.9
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• pp.838-843
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• 2004

• KOREAN ASSOCIATION OF OCCUPATIONAL HEALTH NURSES
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• v.18 no.2
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• pp.17-24
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• 2011

갑상선 호르몬은 2가지 형태, 즉 L-thyroxine(tetraiodothyronine, T4)과 L-triiodothyronine(T3)으로서 갑상선(thyroid gland)에서 합성된다. 요오드는 갑상선 호르몬의 핵심요소이며 음식물에 포함된 요오드는 섭취 후 소장에서 흡수되어 혈류를 통해 갑상선으로 운반되고, 갑상선에서 농축, 산화되어 thyroglobulin이라는 단백질의 구성 아미노산 중 tyrosine에 삽입됨으로써 T4와 T3를 생성하게 된다. 갑상선 호르몬의 합성에는 요오드 이외에도 셀레니움이 필수적이다. 요오드와 셀레니움은 미량원소로서 부족하면, 갑상선 호르몬 결핍 또는 갑상선 비대를 초래할 수 있다.

• Journal of Bio-Environment Control
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• v.7 no.1
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• pp.63-70
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• 1998

This study was carried out to investigate the interaction of selenate and sulfate ion in nutrient solution supplyed with selenate ion. At early growth stage, the growth of Mongolian wormwood was best at 3mM sulfate ion and 2mg/$\ell$Na$_2$SeO$_4$ treatment. As they were grown and matured, at the later growth stage, the effect of antagonism between selenate and sulfate ion on the growth of each plant decreased. At supplying with selenate ion in nutrient solution, the uptake of selenate by plant had negative correlation with sulfate ion concentration in nutrient solution. The higher sulfate ion concentration, the less selenium uptake. However, the effect of antagonistic interaction of selenate and sulfate ion on the selenium uptake increased with plant age. Whereas, the uptake of sulfate ion had positive correlation with sulfate ion concentration in nutrient solution at supplying with selenate ion in nutrient solution. The uptake of sulfate ion increased with increase of sulfate ion concentration in nutrient solution. The effect of this interaction with selenate and sulfate ion increased with growth and maturity of plant. However, at 3mM sulfate ion concentration in nutrient solution, sulfate ion concentration in plant tissue decreased markedly.

• Journal of the Korean Ceramic Society
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• v.11 no.2
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• pp.38-49
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• 1974

운모기판에 증착한 비정형 셀레니움 박막의 결정성장의 형태와 그 변태속도에 대하여 연구하였다 열처리된 박막에서 비정질성분은 CS2에 용해되나 결정질은 아무 변화없이 남아 있으므로 쉽게 현미경을 이용하여 그 모양을 조사할 수 있다. 결정은 (30$^{\circ}$~10$0^{\circ}C$ 온도 범위에서) 박막과 운모기관의 경계면을 따라서 원형상(구상 결정의 이차원 적 모양) 중심으로 부터 일정 속도로 자란다. 또한 필라멘트 형태의 결정이 원형상 결정의 비 규칙적인 부분에서 박막을 뚫고 위로 자란다. 이들 필라멘트형 결정은 자유표면에 도달하여 새로이 자유표면을 따라서 원형상으로 자라게 된다. 경계에 있는 원형상 결정의 두께는 약 500$\AA$정도이고 이것이 비정질 세레니움 박막에서 보이는 "어두어 지는" 현상의 원인이 되고 있음이 밝혀졌다. 원형상 결정은 아주 조그마한 결정 "도메인"으로 구성되어 있으며 이들 "도메인"의 축 방향은 경계면과 나란하고 반경방향에 수직으로 되어 있다. 고온처리에서 얻어지는 규칙적인 결정은 이들 "도메인"이 모여서 "라멜라"를 형성하여 중심부에서부터 뻗어나가고 이들 "라멜라"간의 공간은 불규칙적으로 나열된 "도메인"으로 연결되어 있으며, 고분자 결정에 비하여 훨씬 두껍다. 반경 방향으로의 결정성장 속도는 아주 순도가 높은 박막에서는 시간에 따라 일정하고 주어진 온도에서 재현성이 아주 좋다. 이 실험에서 측정된 성장속도는 지금까지 발표된 어느 실험에서 관측된 것보다 빠르고 또 자유표면에서 자라는 속도에 비해서 약 백 여배나 빠르다. 결장 성장의 온도 의존은 u=6$\times$1015 exp[-32.7(kcal/mol)/RT] cm/sec로 표시할 수 있다.

• Proceedings of the Korean Environmental Sciences Society Conference
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• 2008.11a
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• pp.297-299
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• 2008

시화호 주변 해역에 서식하는 진주담치 내의 위생세균 및 비소(As), 카드뮴(Cd), 크롬(Cr), 철(Fe), 수은(Hg), 망간(Mn), 니켈(Ni), 납(Pb), 셀렌니움(Se) 및 아연(Zn)등의 미량원소들을 분석한 결과를 요약하면 다음과 같다. 본 연구해역의 전 조사정점에서 위생세균이 다소 높은 농도를 보이는 것은 아마도 조사시기가 하계로써 담수유입에 따른 영향으로 보여진다. 미량금속의 농도는 우리나라 식품위생기준 이내의 양호한 농도분포를 보였으며, 비소(As), 크롬(Cr), 니켈(Ni) 및 납의 경우 시화호 및 시화호 외측해역에서 유의한 농도차이(p<0.05)를 나타내지 않았으나 카드뮴 및 망간의 농도의 경우 시화호내에서 다소 높은 농도를 보였다(p<0.05). 반면에 구리, 수은, 셀렌니움 및 아연 등의 농도는 시화호에서 보다 시화호 외측해역에서 다소 높은 농도를 보였다(p<0.05). 또한 각성분간에 상관관계를 살펴보면 비필수원소중 수은과 카드물의 경우 셀레니움과 좋은 정의 상관성를 보이는 것으로 보아 이들 비필수원소의 셀레니움이 진주담치의 황산화성물질로 작용하는 것으로 보여 진다.

• Horticultural Science & Technology
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• v.19 no.4
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• pp.465-470
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• 2001

This study was carried out to investigate the effect of application dosage and methods of selenium (Se) on mineral contents in garlic. The content of Se was higher in upland than paddy fields. Application of higher dosage of Se salt increased higher content of Se in leaf sheath and bulb of garlic. Se was detected also in the non-treated plot but its amount was negligible. Absorption of Se in garlic was higher when Se was applied in the form of sodium selenate. Foliar application of sodium selenate enriched Se content in garlic as compared with the soil dressing. However, Se content in garlic fluctuated depending on growing conditions. Se content of garlic grown on the artificial soil (vermiculite and commercial soil) in the plastic house was higher than the garlic grown in the paddy field. The growth of garlic was not affected by types, dosage and application methods of selenium. Mineral contents in garlic such as Mg, S and K were higher in the selenium treatment than control. However, this trend was not evident according to dosages of selenium fertilizers.