• Korean Journal of Microbiology
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• v.31 no.2
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• pp.166-174
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• 1993

Streptomyces coeUc%r (Muller) cells were treated with $100 \mu$M hydrogen peroxide for I hour and proteins synthesized during hydrogen peroxide stress were labeled with L-[$^{35}S$]-methionine. Total cellular proteins were extracted and analyzed by two-dimensional polyacrylamide gel electrophoresis. In exponential growth phase, synthesis of about 100 proteins was increased by hydrogen peroxide treatment. These proteins were named as Pin (£eroxide-inducib]e) proteins and classified into 4 subgroups according to their induction time after hydrogen peroxide treatment. About 60 of them were found to be induced within 20 minutes and maintained throughout I hour of treatment. In stationary growth phase. synthesis of 62 proteins was increased by hydrogen peroxide and 21 of them were the same Pins found in exponential growth phase. Proteins from the mutants which are resistant to hydrogen peroxide were obtained in exponential growth phase and compared with those from the wild type on two-dimensional gel. The three mutants, N7, N9. and N24, were found to have higher constitutive leve]s of ]5, 17, and 15 Pin proteins respectively, than the wild type. 9 of these Pin proteins (D74.7a, E76.0c, E23.3. F50.7, F47.2a. F25.5, G39.6b, G24.0, H39.6a) increased in two of the three mutants and 3 proteins (F39.7, H6I.7. 120.8) increased in all of the three mutants. These proteins might play important roles in the response of S. coelic%r to hydrogen peroxide.

• Cartoon and Animation Studies
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• s.51
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• pp.225-254
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• 2018

For the domestic web-toon industry, a new industrial environment has been created by the growth various domestic and international factors, such as technology development, the increase of platforms, charged web-toon, and globalization. Although the role of the agency has not been emphasized at the formation and introduction time of the web-toon, the role growth of the agency has been regularized with the expanding of the web-toon industry. The expending web-toon industry is due to the introduction of smart-phone, by which people can consume the web-toon without any limit of time and place, so the web-toon industry has been growing rapidly. Thereafter the production of the second contents using the web-toon IP has been actively carried out and the activity area of the web-toon artist has been diversified, so the necessity of the specialized web-toon agency has begun to be brought in earnest. In this study, the web-toon industry has been, firstly, classified as transition period of cartoon industry, foothold formation period of web-toon, introduction period of web-toon industry, expansion period, and maturity period according to the industrial life cycle theory. As a result, the web-toon agency has been emerged from the expansion period of web-toon industry, and the role of agency, to prevent web-toon industry entering into declining period from its maturity period, has been researched in this study.

• Journal of Nutrition and Health
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• v.48 no.2
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• pp.149-156
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• 2015

Purpose: This study examined the effects of combined intervention of isoflavones and exercise on bone mineral density, bone mineral content, and biochemical bone markers. Methods: Forty rats were divided into four groups; Control, Isoflavones (IF), Isoflavones + Running (IFR), and Isoflavones + Swimming (IFS). All of the rats in this study were fed an experimental diet and deionized water ad libitum for nine weeks. Bone mineral density (BMD) and bone mineral content (BMC) were estimated using PIXImus (GE Lunar Co, Wisconsin.) in spine and femur nine weeks after feeding or training. Results: The combined intervention did not affect weight gain, mean food intake, or food efficiency ratio. The serum concentrations of ALP and osteocalcin were not significantly different by combined intervention. The urinary DPD crosslinks values were not significantly different by combined intervention. There were no significant differences in serum PTH, calcitonin, and estradiol among all groups. Spine BMD, spine BMC and femur BMC were not significantly different by combined intervention. However, femur BMD was significantly higher in the IFR group than in the control group. Compared with the control group, spine BMD, spine BMC, and femur BMD per weight were markedly increased in the isoflavones supplementation and combined intervention group. In addition, femur BMC per weight was significantly higher in the IFS group than in the control group. Compared with the isoflavones supplemented group, BMD and BMC were not significantly different by combined intervention. Conclusion: It can be concluded that isoflavones supplementation or combined intervention of isoflavone and exercise had a beneficial effect on spine and femur peak bone mass in growing female rats.

• Journal of the korean academy of Pediatric Dentistry
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• v.47 no.3
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• pp.235-247
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• 2020

The purpose of this study was to evaluate the skeletal and dentoalveolar effects and optimal timing for treatment of class II malocclusion with functional appliances in children and adolescents. A group of 30 patients with class II malocclusion were divided into 3 groups according to their use of functional appliance: Twin block, Activator, Fränkel appliance. The group was also divided into 2 groups according to the cervical vertebrae maturation method. Lateral cephalometric radiographs were analyzed pretreatment (T0) and posttreatment (T1). Among the functional appliances, treatment with Twin block and Activator showed significant increase in the length of the mandible (Co-Gn) and the lower anterior facial height (ANS to Me), whereas the overjet and overbite were significantly reduced. Treatment with Fränkel appliance showed significant improvement in the relationship of maxilla and mandible. In addition, if the functional appliance was used during the period of pubertal growth peak, there was a significant increase in mandibular length, improvement in the relationship of maxilla and mandible, labial inclination of lower incisors and decrease in overjet compared to the treatment before pubertal growth peak. Therefore, this study indicates that using functional appliances for patients with class II malocclusion is effective and the optimal timing for using functional appliances is during pubertal growth peak.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.15 no.1
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• pp.225-235
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• 2020

The Korean government is attempting to promote technology-based start-ups and venture firms that can lead to new national growth engines being developed. Although government support policies focus on improving survival rates, strategic tools for sustainability management based on a continuing company's assumption are also relevant. Previous studies indicate corporate social responsibility (CSR) as an important strategic tool for the management of corporate sustainability. This research is an exploratory study that seeks to empirically analyze the applicability of such CSR to venture firms. Existing previous studies have been carried out by large companies and surveys, and there are limitations that do not reflect the characteristics of companies. To complement the shortcomings of previous studies and propose practical consequences, this study conducted an empirical analysis using raw data from government approval statistics to identify the growth stages of venture firms. Using the 2018 Survey of Korea Venture Firms, we identified the growth stages of domestic venture firms and used the data envelopment analysis (DEA) to investigate the effect of CSR activities on managerial efficiency. The analysis found that CSR during start-up and early growth cycles did not affect managerial performance. The organization that conducted enthusiastic CSR activities performed better than those that did not perform CSR activities since the rapid growth era. Ultimately, the scale efficiency of venture business was the highest from the rapid growth era when the CSR was not done. This study is a pioneering study that found that after the period of high growth, venture firms' CSR activities can affect managerial performance. Therefore, it is important to advise applicable policies and business decision-makers that CSR practices can be a tactical resource for improving performance of management.

• Journal of Nutrition and Health
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• v.35 no.4
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• pp.409-413
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• 2002

The purpose of this study was to determine to which differences in the source of protein (soy vs casein) and of isoflavones in soy protein are responsible for differential effects of bone mineral density and bone mineral content. Thirty 21-d-old Sprague-Dawley young rats were divided into 3 groups: the control group was find a casein-based diet, the soy concentrate group was fed soy protein with totally reduced isoflavones content (isoflavone 0.07 mg/g protein), and soy isolate group was fed with a higher isoflavone content (isoflavone 3.4 mg/g protein) than normal. The animal was scanned to determine the BMD and BMC using dual energy X-ray absorptiometry (DEXA, Lunar Corporation, Madison, WI). The soy concentrate group had significantly higher total body calcium/weight and total mineral content/weight than the casein group. The soy isolate group had significantly greater total bone mineral density/weight, spine bone mineral density/weight, and femoral bone mineral density (in g/$\textrm{cm}^2$ than the control and soy concentrate group. The findings of this study suggest that soy protein and isoflavones in soy protein are beneficial for bone-formation in growing male rats. Therefore exposure to these soy protein and isoflavones early in life may have long-term health benefits for bone diseases such as osteoporosis.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.13 no.6
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• pp.177-189
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• 2018

Business environment is always full of challenges. Despite various strategic efforts, there are so many failure cases of misfit. With the weaker resource base and institutional foundation, startup firms find it more difficult to find the right spot in the stiff competition. In the middle of evolutionary process, the startup firms need proper strategies meeting the differential challenges along the multiple stages of growth. Following the idea of product life cycle, this study applies the four stages of growth-startup, initial growth, accelerated growth, matured, and decliing. The next step for the startup manager is meeting each stage of growth with proper strategic efforts, including strategy, structure, decision-making pattern, and control method. When the knowledge factor is introduced, there is a potential for higher performance. Based on the 'Detailed Survey on Startup Ventures in 2017,' this study explores the impact of the government subsidy program on the firm competitiveness and performance-along the four stages of growth. In each stage, the strategy factors showed differential impact.

• Informatization Policy
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• v.26 no.2
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• pp.24-45
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• 2019

This paper analyzes the size of direct and indirect impact of the information and communication technology(ICT) producing sector to the Korean economic growth We first divide the entire economy into the ICT producing sector and the ICT using sector, and estimate the contributions to the economic growth by each sector. We also try to answer the question on what the possible causes of the ICT producing sector's contribution are to growth. In oder to find the answer, we focus on the change in the relative prices of ICT products produced in the ICT producing sector and examine the long-term relations among the relative prices of ICT products, the ratio of ICT products used in the ICT using sector as an intermediate input, and the output of the entire economy. We find that the overall economic growth has been weakened but the ICT sector's contribution to the growth has increased. Specifically, the indirect contribution of the ICT producing sector, through the ICT using sector, to economic growth was greater than the direct contribution of the ICT producing sector itself. We also find a stable, long-term negative relation between the relative prices of ICT products produced in the ICT producing sector and the ratio of ICT products as an intermediate input in the ICT using sector. In addition, the decrease in the relative prices of ICT products produced in the ICT producing sector increases the use of ICT products in the ICT using sector and the output of the entire economy. These findings can be interpreted that the price decrease in the ICT products improves the production efficiency in other sectors and helps directly and indirectly, accelerating growth of the entire economy.

• 건강소식
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• v.37 no.1
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• pp.32-33
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• 2013

새해를 맞아 흔히 세우는 계획의 주제로는 무엇이 있을까? 저축, 금연, 여행, 자격증, 학습 등 그 종류도 다양하다. 하지만 이런 많은 계획을 세우기에 앞서 꼭 챙겨야 할 것이 있다. 바로 모든 계획의 밑바탕이 되는 '건강 계획'이다. 성장기인 10대부터 청장년층을 넘어 노년기까지, 우리가족의 연령대별 건강계획을 세워보자.

• Aerospace Industry
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• v.67
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• pp.14-15
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• 1999

아시아의 경제위기로 고전하고 있는 대형항공기 분야와는 달리 비즈니스 제트기 시장은 현재 호황을 기록하고 있다. 현재 우리나라 항공산업은 주로 보잉과 에어버스를 중심으로 부품을 납품하고 있다. 향후 안정적인 부품 공급과 확대를 위해서 수요시장의 다양화를 추구하는 것도 하나의 방법이 될 것이다. 본지에서는 최근 호황을 누리고 있는 비즈니스 제트기 시장의 동향을 게재하였다.