• Clinical and Experimental Pediatrics
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• v.46 no.3
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• pp.277-283
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• 2003

Purpose : Craniopharyngiomas are often accompanied by severe endocrine disorders. Although there is universal growth hormone deficiency(GHD), the resulting growth pattern is very heterogeneous. We report the growth and endocrine outcome of 44 children with craniopharyngioma, with emphasis on initial symptoms, growth before and during growth hormone(GH) treatment and spontaneous growth in spite of GHD. Methods : We performed a retrospective study of 44 children treated at our centre between 1984 and 2002. Results : About 30% of patients had symptoms suggesting endocrine disorder at diagnosis. After surgery, multiple endocrinopathies were almost universal. Before GH therapy, height velocity was $8.00{\pm}2.71cm/yr$ in the normal growth group(n=11) and $1.79{\pm}1.10cm/yr$ in the subnormal growth group(n=7) during the first year and during the second year, $6.76{\pm}2.49cm/yr$ and $2.29{\pm}1.33cm/yr$, respectively. There was no difference of body mass index(BMI) change between before and after surgery in the two groups. Height standard deviation score(SDS) was $-1.46{\pm}0.74$ in the normal growth group and $-0.43{\pm}0.97$ in the subnormal growth group. Before GH treatment height SDS was $-1.31{\pm}1.25$ and BMI was $20.46{\pm}3.60$. During GH treatment, height SDS increased to $-0.60{\pm}1.37$ in the first, and to $-0.41{\pm}1.54$ in the second year(P<0.05), but BMI did not change significantly. Conclusion : The endocrine morbidity could develop in most children with craniopharyngioma before and after the operation and should be managed properly. Although all treated patients benefit from GH therapy, further studies are necessary to find out the possible mechanism of growth regulation in normally growing children, despite GH deficient.

• Journal of Yeungnam Medical Science
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• v.21 no.1
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• pp.23-39
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• 2004

Background: It is important to provide health education to students to ensure a healthy life. Using the internet for health education may be a way to overcome the practical barriers to health education such as time and content. This study was conducted to investigate the demands for health education using the internet. Subjects and methods: Six hundreds and twenty-four and male female students in middle and high schools, who lived on Gyeongju-si and Seongju-gun in Gyeongsangbuk-do province, were interviewed by means of structured questionnaires, from March 5 to March 28, 2003. Results: More than 90% of the subjects had their own computers, and nearly 38% of those possessing their own computers had accessed internet sites related to health and medicine. Middle school students and in particular, female students were more desirous for health education through e-mail. Regarding content, the three major topics which the respondents wanted to learn about were healthy lifestyles, growth and development, and disease prevention. In terms of the interval for providing educational materials, over half of the students wanted information once a week. Most of the students wanted to have the quantity of the material be one page. In addition, there were numerous additional topics requested by the students such as sleep and health, contraception and family planning, safety education, cancer prevention, emotional instability of juveniles, the utilization of medical care facilities, stress management, etc. Conclusion: The students had a desire for health education through the use of e-mail, and methods and materials should be developed for appropriate health education using the internet.

• Economic and Environmental Geology
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• v.54 no.2
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• pp.233-245
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• 2021

Many studies on the microstructures in rocks have been conducted using experimental methods with various equipment as well as natural rock studies to see the development of microstructures and understand their mechanisms. Grain boundary migration of mineral aggregates in rocks could cause grain growth or grain size changes during metamorphism or deformation as one of the main recrystallization mechanisms. This study suggests improved ways regarding the analog material experiments with reformed equipment to see sequential observations of these grain boundary migration. It can be more efficient than the existing techniques and carry out an appropriate microstructure analysis. This reformed equipment was implemented to enable optical manipulation by mounting polarizing plates capable of rotating operation on a stereoscopic microscope and a deformation rig capable of experimenting with analog materials. The equipment can automatically control the temperature and strain rate of the deformation rig by microcontrollers and programming and can take digital photomicrographs with constant time intervals during the experiment to observe any microstructure changes. The composite images synthesized using images by rotated polarizing plates enable us to see more accurate grain boundaries. As a rock analog material, norcamphor(C7H10O) was used, which has similar birefringence to quartz. Static grain growth and simple shear deformation experiments were performed using the norcamphor to verify the effectiveness of the equipment. The static grain growth experiments showed the characteristics of typical grain growth behavior. The number of grains decreases and the average grain size increases over time. These case experiments also showed a clear difference between the growth curves with three temperature conditions. The result of the simple shear deformation experiment under the medium temperature-low strain rate showed no significant change in the average grain size but presented the increased elongation of grain shapes in the direction of about 53° regarding the direction perpendicular to the shearing direction as the shear strain increases over time. These microstructures are interpreted as both the plastic deformation and the internal recovery process in grains are balanced by the deformation under the given experimental conditions. These experiments using the reformed equipment represent the ability to sequentially observe changing the microstructure during experiments as desired in the tests with the analog material during the entire process.

• Korean Journal of Ichthyology
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• v.18 no.4
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• pp.311-318
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• 2006

Ultrastructure of germ cells, the cyst epithelial cells and interstitial cells during spermatogenesis of the stone flounder, Kareius bicoloratus (Pleuronectidae) sampled on the west coast of Korea were investigated by electron microscopic observations. In the primary spermatocyte, the synaptonemal complexes appear in the zygotene stage of the prophase during maturation division. In the growing testis, especially, the interstitial cells (Leydig cells) appear near the primary, secondary spermatocytes and spermatids. Well-developed interstitial cells (steroid hormone secreting cells) which are located in the interlobular space in growing testis have three morphological characteristics of a vesicular nucleus, mitochondria with tubular cristae and smooth endoplasmic reticulum. During spermatogenesis, the primary and secondary spermatocytes attach to the cyst epithelial cell (Sertoli cell) having an elongated ovoid or triangular nucleus and several mitochondria in the cytoplasm. In the growing testis, lipid droplets, the mitochondrial rosettes and glycogen particles appear in the cytoplasm of the cyst epithelial cells near the secondary spermatocytes and spermatids. Particularly, the mitochondria, endoplasmic reticulum, little lipid droplets and the large amount of glycogen particles are present in the cytoplasm of the cyst epithelial cell in the late growing testis. In the late stage of spermiogenesis, the proximal centriole is joined to the nuclear envelope, the distal centriole forms the basal body of the flagellum and gives rise to the axial filament of the flagellum. No acrosome of the sperm is formed as seen in other teleost fish. The head of the spermatozoon is approximately $3{\mu}m$ in length and its tail is about $30{\mu}m$ in length. The axoneme of the tail flagellum of the spermatozoon consists of nine outer doublet microtubules at the periphery and two centrial singlet microtubules at the center. The spermatozoon of this species has two axonemal lateral fins. Especially, the cyst epithelial cells which located near groups of gametes in the various stages, show three functions: nutrition, phagocytosis and steroidogenesis. Especially, the nuclei of cyst epithelial cells in the recovery stage of the testicular developmental stages appear to be irregular in shape after spermiation. Of three functions of the cyst epithelial cell, several characteristics of phagocytosis are showed in the cytoplasm of the cyst epithelial cells in the recovery stage of the testicular developmental stages. At this stage, therefore, it is assumed that the cyst epithelial cells are involved in degeneration and resorption of undischarged germ cells after spermiation.

• Journal of the Economic Geographical Society of Korea
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• v.20 no.1
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• pp.70-83
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• 2017

Traditionally, economic growth has been uneven over the space. It has also been true for the recovery from social and economic crisis in old industrial areas of the advanced economies. Even if many of such old industrial areas were seriously affected by de-industrialization, some areas have been showing progress, while others have not been so. While interpreting this phenomenon used to be a key issue in economics, main stream liberal economic theorists' explanation was uneven distribution of economic resources, such as raw materials, labour and money. However, some revolutionary economic theorists have brought in the concept of "history" in explaining the phenomenon. Path dependence theorists, for example, interpretate the emergence of different growth paths with the concept of historical accidents. This contrasts to the recent argument of the group of scholars suggesting the concept of "regional resilience," who argue that uneven growth and different growth paths are originated from different regional resilience. This paper introduces the backgrounds, characteristics and utilities of the two theories: path dependence theory and the concept of regional resilience.

• Archives of design research
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• v.16 no.3
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• pp.421-430
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• 2003

During the past years private brand sales in supermarkets grew more rapidly then manufacturer brands. Store brand products account for more than one-fifth of total volume sales in the United States and are outpacing national brand growth. The most compelling reason for this increased presence in the market is their price differential with national brands. A general tendency of store brand sales in Korea also is on the increase over the years. On the other hand there is something yet to learn in the field of private label. The research has resulted in consumers changing their perception of store brand products from one of low quality to one of premium quality. Reduced price is not the only answer for store brand to be survive. The new marketing approach should include better packaging improved quality and specific advertising and promotional programs designed to increase customer awareness and sales of store brand products.

• Journal of the Economic Geographical Society of Korea
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• v.14 no.2
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• pp.225-239
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• 2011

The main purpose of this paper is to analysis the growth process of new emerging Korean society in Georgia, the USA by investigating changes in the regional distribution of Korean business located in metro Atlanta region. More specifically, it aims to identify the characteristics of spatial distribution of Korean business in metro Atalanta through their locational trends since 1980s. To this end, it has explored the history of Korean migration into Georgia and the locational trends of Korean firms in metro Atlanta by industries. As a result, the main location of Korean firms has expanded into the northeastern regions of Atlanta due to the development of transportation, new regional development, education environment and changes in residential distribution by ethnic. Also, the main Korean business has transformed from retails and restaurant to real estate and finance because of changes in market strategies, institutions and Korean local migration.

• Journal of Gifted/Talented Education
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• v.11 no.3
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• pp.245-270
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• 2001

Math and Science Olympians participated in a study of the role of environmental influences in their talent development. The questions they got was about family and school factors contribute / or hinder to the development of their scientific talents, and the parents' child rearing styles. The questionnaires were originally developed by Campbell(1996) for cross-cultural studies. The major findings were as follows: ⑴ The professional job of the Olympians'father, the high SES, Their parents'discovering their child's talents were positive factors, ⑵ Their family support and learning environment were reported strong and positive, especially books and reading atmosphere, ⑶ The Olympians participated in the accelerated and enriched educational programs, ⑷ The quality of the class and the rigidity of the curriculum were hindering factors, ⑸ Their parents'rearing style were permissive, affective, and supportive.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.9
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• pp.454-464
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• 2018

The OECD estimates that a high concentration of intangible capital is in the richest countries of the world. Studies show that intangibles have a positive relation with economic growth. However, different types of intangibles can have different impacts on economic performance. Therefore, this paper attempts to distinguish the differences within the intangibles in influencing economic growth by analyzing three different characteristics of the intangibles. Three main types of intangibles (computerized information, innovative property and economic competencies) are analyzed based on the degree of tacitness, the process of creation and diffusion, and the level of embedded value-added. This research uses Polanyi's classification of tacitness of knowledge, the Nonaka-Takeuchi Model and the "smiling curve" to find that not only investing more in intangible capital but also developing more "tacit" type of intangibles are important for economic growth.

• Journal of Korean Society for Geospatial Information Science
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• v.17 no.3
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• pp.41-48
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• 2009

This study investigated the characteristics of spatial expansion/centralization and the spatial structural change of urban. The data used in analysis were urban population, employment, building floor area, and land price. The analysis was performed for the data of 1995, 2000, and 2005 during 10 years after 1995. The method of research was as follows; The movement of mean center and standard distance/standard deviation ellipse was estimated to investigate the urban growth change. The result of Moran's I analysis showed a clustered pattern, not a dispersed pattern, however; the effect was not significant. The town area requires the well-ordered urban planning such as land use. The contours map demonstrates that a monopole structure was generally transformed into a multicentralization structure. The development of mutural connection axis among central street roads was fragile.