• Journal of the Korean Applied Science and Technology
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• v.38 no.4
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• pp.915-921
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• 2021

In this study, we designed pantothenic acid (PA) loaded solid lipid nanoparticles (SLNs) for enhanced skin penetration of PA that is used for moisturizing agent in cosmetics with hydrophilic property. SLNs were prepared using various lipids and surfactants. PA loaded SLNs were fabricated using double emulsion method. The fabricated PA loaded SLNs assessed particle size, polydispersity index, zeta potential, loading capacity. Skin penetration study was conducted using artificial skin tissue originated from human epidermis as one of the reconstructed human epidermis models. The mean particle size and zeta potential of SLNs ranged from 192.15 nm to 369.87 nm and -21.39 mV to -40.55 mV, respectively. The loading efficiency and loading amount of PA loaded SLNs were ranged from 44.36% to 57.16% and 12.60% to 16.36%, respectively. The results of penetration demonstrated that all SLNs improved PA skin penetration. In addition, the amount of PA from SLNs were approximately 3.8 - 8.8 times higher than that from PA solution. Therefore, the fabricated SLNs demonstrated the enhancment of skin penetration of PA. Particularly, the SLN, which used glyceryl behenate and Span 60, showed optimal skin penetration of PA.

• Journal of The Korean Society For Urban Railway
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• v.6 no.4
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• pp.319-326
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• 2018

The safety interval to prevent collision between trains in a train control system is based on the braking distance according to the emergency braking of the train. The evaluation of the braking performance is based on the longitudinal train dynamics or the commissioning test in the test track, but since the conditions such as the weakening of the adhesion coefficient between the wheel and rail can not all be considered, these conventional methods are not sufficient to design of the train control systems. Therefore, in this study, the Monte Carlo Method (MCM) which can consider various environments is used to analyze braking performance and limitations. The braking model is based on the air braking used in the emergency braking and is modeled to take into account the braking pressure, efficiency, friction coefficient, adhesion condition, and vehicle mass distribution. It is confirmed that braking performance can be improved by controlling the quality of braking device. In addition, the change of the braking performance was confirmed according to the vehicle constituting the train. The results of this study are expected to be used as basic information for designing safety clearance for the train control systems and as a basis for improving the braking performance of railway vehicles.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.2
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• pp.617-624
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• 2021

Concrete-filled steel tubular columns can improve the strength and deformation capacity of structures, thereby enabling the development of efficient structures. The Korean design standard (KDS41) regarding concrete-filled steel tubular structures, established by the architectural institute of Korea in 2005, was revised in 2009 and 2016. The objective was to understand the compressive strengths and deformation capacity of stub columns for concrete-filled square steel tubes under uniaxial compression and validate the KDS41's standard code for necessary corrections. Experiments were conducted on 26 specimens with parameters, such as the width-thickness ratio of cold-formed square tubes. The following values of the stub columns for concrete-filled square steel tubes were obtained: compressive strengths, relationship between the axial load and axial displacement, and failure modes. An analysis of these results enabled an understanding of the concrete-filled effect and the influence of the wide-thickness ratio. The compressive strengths of filled concrete saw a 9% increase compared to a state of uniaxial stress, which must be noted in a future edition of KDS41. After benchmarking the results regarding square steel tubes generated by cold forming to the guidelines provided by the KDS41, the KDS41's value of 2.26 for the limiting width-to-thickness ratio for the compact section was found to be inflated. With a safety concern, this paper proposes a more conservative value of 1.35.

• Journal of IKEEE
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• v.26 no.3
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• pp.515-519
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• 2022

In this paper, we propose the development of a high-sensitivity entry-level nuclide analysis module. The proposed measurement sensor module consists of an electronic driving circuit for nuclide analysis resolution, prototype production with nuclide analysis function, and GUI development applied to prototypes. The electronic part driving circuit for nuclide analysis resolution is divided into nuclide analysis resolution process by the electronic part driving circuit block diagram, MCU circuit design used for radiation measurement, and PC program design for Spectrum acquisition. Prototyping with nuclide analysis function is made by adding a 128×128 pixel OLED display, three buttons for operation, a Li-ion battery, and a USB-C type port for charging the battery. The GUI development department applied to the prototype develops the screen composition such as the current time, elapsed measurement time, total count, and nuclide Spectrum. To evaluate the performance of the proposed measurement sensor module, an expert witness test was conducted. As a result of the test, it was confirmed that the calculated result by applying the resolution formula to the Spectrum (FWHM@662keV) obtained using the Cs-137 standard source in the nuclide analysis device had a resolution of 17.77%. Therefore, it was confirmed that the nuclide analysis resolution method proposed in this paper produces improved performance while being cheaper than the existing commercial nuclide analysis module.

• Journal of the Korea institute for structural maintenance and inspection
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• v.26 no.6
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• pp.47-53
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• 2022

As the limit state design method is applied as a method of designing concrete structures, the ultimate state is considered in the analysis or design. In fact, when the reinforced concrete member bears tensile force, the force is transmitted from the rebar to the concrete, and the structure bears the tensile force to the ultimate state even after yield. Therefore, the accurate evaluation of behavior after yield, it is necessary to study the tension stiffening effect after yield of the flexural member. In this study, a 4-point bending test was conducted on the RC simple beam having a rectangular cross section of the double reinforcement, and the behavior of the member was analyzed in detail using the image analysis method. Using the analysis results, the estimation formula for the tension stiffening effect after yield was proposed, and the applicability of this was verified through the experimental results of existing study. The difference between the ultimate strain and the yield strain representing the ductile behavior of the member is similar to the experimental results. The prediction of the proposed formula is relatively accurate.

• Journal of the Korean Society of Propulsion Engineers
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• v.26 no.4
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• pp.54-63
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• 2022

A 3-tonf class liquid rocket engine that powers the upper stage of a small launcher and lifts 500 kg payload to 500 km SSO is designed. The small launcher is to utilize the flight-proven technology of the 75-tonf class engine for the first stage. A combination of liquid oxygen and liquid methane has been selected as their cryogenic states can provide an extra boost in specific impulse as well as enable a weight saving via the common dome arrangement. An expander cycle is chosen among others as the low-pressure operation makes it robust and reliable while a specific impulse of over 360 seconds is achievable with the nozzle extension ratio of 120. Key components such as combustion chamber and turbopump are designed for additive manufacturing to a target cost. The engine system provides an evaporated methane for the autogenous pressurization system and the reaction control of the stage. This upper stage propulsion system can be extended to various missions including deep space exploration.

• Composites Research
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• v.20 no.3
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• pp.8-16
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• 2007

Bending collapse of light-weight square tubes used for vehicle structure components is a dominant failure mode in oblique collision and rollover of vehicles. In this paper bending performances of aluminum-GFRP hybrid tube beams were evaluated in relation with bending deformation behavior and energy absorption characteristics. Aluminum/GFRP hybrid tube beams fabricated by inserting adhesive film between prepreg and metal layer were used in the bending test. Failure mechanisms of hybrid tubes under a bending load were experimentally investigated to analyze the bending performance as a function of ply orientation and composite layer thickness. Ultimate bending moments and energy absorption capacity of hybrid tube beams were obtained from the measured load-displacement corves. It was found that aluminum/GFRP hybrid tubes could be converted to rather stable collapse mode showing excellent energy absorption capacity in comparison to the pure aluminum tube beams. In particular, the hybrid tube beam with $[0^{\circ}/90^{\circ}]s$ composite layer showed a large improvement by about 78% in energy absorption capacity and by 29% in specific energy absorption.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.29 no.5A
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• pp.511-518
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• 2009

This study was intended to compare and evaluate the adhesion of High flowing Self-compacting Concrete (HSCC), Conventional Concrete (CC) and deformed bar based on concrete strength 3 (30, 50 and 70 MPa), among the factors affecting the bond strength between concrete and rebar, after fabricating the specimen by modifying the rebar position at Horizontal reinforcement at bottom position (HB), horizontal reinforcement at top position (HT) and vertical reinforcement type (V). As a result of measuring bond strength of HB/HT rebar to evaluate the factor of the rebar at top position, the bond strength of HB/HT rebar at 50 and 70 MPa was 1.3 or less and at 30 MPa, HSCC and CC appeared to be 1.2 and 2,1, respectively. Thus, when designing the anchorage length according to the concrete structure design standard (2007) at HSCC 30, 50 and 70 MPa, it would be desirable to reduce the correction factor of anchorage length of the horizontal reinforcement at top position, which is suggested for the reinforcement at top position, to less than 1.3 of CC.

• Annual Conference of KIPS
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• 2007.05a
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• pp.540-543
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• 2007

최근의 그리드 컴퓨팅 시스템 환경은 단일 환경에서 작게는 2~4CPU, 많게는 수백 CPU 이상의 시스템으로 구축되고 있고, 더욱이 지역적으로도 멀리 떨어져 있다. 따라서 이를 운용하는 기업에서는 시스템의 사용 현황을 신속하게 분석할 필요가 있다. 그러나 이렇게 혼재된 이 기종 및 컴퓨팅 환경하에서의 각 지역별 시스템 사용현황을 효과적으로 분석 한다는 것은 매우 어려운 일이다. 기존에 사용되어 온 그리드 컴퓨팅 시스템 환경에서의 사용율 관리 방법들은 Queueing 시스템이 가지고 있는 Accounting 분석 명령어로 text 형태의 Accounting raw data 의 결과를 추출하여 가공 처리하므로 데이터 증가 시 반응 속도가 현격하게 느려지는 상황이 발생한다. 또한 원격지 그리드 컴퓨팅 시스템 군의 사용율 분석은 데이터 분석 시 매번 원격지접근 절차를 사용하여 그리드 컴퓨팅 시스템 군에 접근한 후 해당 로컬 시스템 분석을 해야 하고 각 원격지시스템군별로 추출 된 데이터를 통합 관리해야 하는 문제점을 가지고 있다. 따라서 이러한 문제점을 해결하고자 하는 것이 본 논문에서 제안하는 3-tier 구조의 GSA(Grid System Account)이다. 제안한 GSA 는 각 원격지 별 데이터를 객체화하여 Database 에 저장 함으로써 데이터 분석 시 효과적으로 처리할 수 있으며, 다수의 원격지 그리드 컴퓨팅 시스템 군에 대한 복합적인 분석이 필요할 때 효율적으로 대처할 수 있다. 본 논문에서는 GSA 의 설계방법을 제안하고 구현하여 실 성능을 시험함으로써 보다 효율적인 그리드 컴퓨팅 시스템의 사용율 분석 관리가 가능함을 보였다.포는 감수성을 보이지 않았다. 따라서 위의 결과로부터 SLT-I에 감수성을 보이지 않은 Raw264.7세포를 대상으로 Gb3 발현 정도와 SLT-I의 세포독성의 관계를 규명하고자 Gb3의 발현을 증가시킨 후 SLT-I의 세포독성을 재차 평가하였다. 이 결과 $TNF-{\alpha}$의 처리에 의하여 6 hrs에 Gb3의 발현이 정점(43.5%)에 이르렀으며 36 hrs에 정상 수준(25.0%)으로 환원되었다. 그러나, Gb3의 발현이 증가함에도 불구하고 SLT-I의 세포독성에는 변화가 관찰되지 않았다. 따라서, SLT-I에 의한 세포독성은 세포의 종류에 따라서 다르며 또한, Gb3의 발현정도에만 의존적이지는 않을 것으로 생각된다. 이와 같은 결과는 E. coli 0157의 감염증 병인 연구에 있어 SLT-I과 Gb3의 발현의 상관관계에 대한 보다 심도 있는 연구가 필요함을 시사한다.만 분할률, 배반포 형성률 및 배반포의 세포수를 증가시키는 것으로 사료된다.수의 유출입 지점에 온도센서를 부착하여 냉각수의 온도를 측정하고 냉각수의 공급량과 대기의 온도 등을 측정하여 대사열의 발생을 추정할 수 있었다. 동시에 이를 이용하여 유가배양시 기질을 공급하는 공정변수로 사용하였다 [8]. 생물학적인 폐수처리장치인 활성 슬러지법에서 미생물의 활성을 측정하는 방법은 아직 그다지 개발되어있지 않다. 본 연구에서는 슬러지의 주 구성원이 미생물인 점에 착안하여 침전시 슬러지층과 상등액의 온도차를 측정하여 대사열량의 발생량을 측정하고 슬러지의 활성을 측정할 수 있는 방법을 개발하였다.enin과 Rhaponticin의 작용(作用)에 의(依)한 것이며, 이

• Journal of the Korean Geotechnical Society
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• v.29 no.4
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• pp.23-32
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• 2013

In order to evaluate the bearing capacity behaviour of a monopod suction bucket foundation for an offshore wind tower at the western sea of Korea, a centrifuge load test and numerical analyses were performed. The monopod bucket foundation was designed to be installed in a silty sand layer. The model soil was prepared to simulate a target site by using soil samples having similar properties and controlling relative density. In-flight miniature cone penetration test and bender element array were used to confirm that the model soil had represented the target site conditions. The load - rotation curve of the centrifuge load test was analysed. A series of numerical analyses were performed to validate the experimental conditions. Self-weight of the model, distance to the boundary and elastic modulus of the soil layer were varied to study their effects on the load - rotation curves.