• Proceedings of the KSMRM Conference
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• 2001.11a
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• pp.114-114
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• 2001

목적： 열적인 방법으로 시술을 할 때 발생한 생체 조직의 온도 변화는 생체조직의 전기임피던스 변화를 야기하는데 이 전기임피던스 변화가 자기공명영상의 위상에 어떠한 영향을 미치는지를 분석하고자 하였다. 대상 및 방법： 생체조직의 전기임피던스는 조직부위에 따라 다르나 온도계수가 평균적으로 -2%/$^{\circ}C$에 이를 만큼 온도에 민감한 특성을 가지고 있다. 이러한 특성을 감안하여 유한요소법을 이용하여 자기공명영상의 위상을 계산하여 보았다. 그 결과를 토대로 0.3Tesla 자기공명영상시스템으로 팬텀을 촬영하여 자기공명영상의 위상을 구하였다.

• Proceedings of the KSMRM Conference
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• 2002.11a
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• pp.100-100
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• 2002

목적： 인체에 전류를 주입하면 체내 생체조직의 임피던스 분포에 따라서 전류밀도 분포가 결정된다. 이러한 전류밀도 분포를 MRI를 이용하여 고해상도로 얻어내면 인체 내부의 임피던스 영상을 구성할 수 있다. 이는 기존의 전기 임피던스 단층 촬영법이 갖는 여러 한계를 극복할 수 있으며 이로부터 생체의 기능에 대한 다양한 정보를 추출할 수 있게 된다. 본 논문은 3차원 팬텀 내부의 전류밀도 분포를 영상화하고 이것으로부터 인체내부의 임피던스 영상을 얻어내는 실험 결과를 기술한다.

• Journal of IKEEE
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• v.25 no.3
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• pp.445-450
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• 2021

Bio-impedance measurement is a measurement device that can be used to obtain biometric information and diagnose skin diseases using convenience, low cost, and low cost devices. In this study, the bio-impedance was measured using a direct dry gold electrode and a simulation study through animal bio modeling to obtain biometric information in a biometric form. Impedance was measured by inserting electrodes into subcutaneous areas of animal tissue and applying frequencies of 100 uA, 1-100 kHz using a two-electrode method. As a result of the measurement, the resistance of the electrodes is measured high at 5 mm electrodes compared to 7.5 mm and 10 mm electrodes based on 5 mm electrodes. Based on the 5 mm electrode, an average difference of 1.49% was found for the 7.5 mm electrode in the total frequency range, and the impedance difference was confirmed to be 2.624% for the 10 mm electrode. In the future, the research results are expected to be valuable in designing and manufacturing electrodes for bio-inserted electrocardiogram sensors.

• Journal of Platform Technology
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• v.9 no.2
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• pp.38-45
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• 2021

A frequently used bioimpedance analytical method in Korea is the segmental multi-frequency BIA (SMF-BIA) method, but it is not directly determined at a segmented impedance. This study was to compare SMF-BIA determinations with direct segmented determinations for accuracy and appropriateness of segment parameters. This study is to compare the segment parameters, accuracy and appropriateness of the multi-frequency segmental bioimpedance analysis. To this end, 108 elderly individuals were measured. Segmented bioelectrical measurements obtained from a SMF-BIA (Inbody S10) at 50 kHz and measured with a phase sensitive single frequency device (SF-BIA, bia-101, RJL / akern systems) were compared. The significant difference (%) was demonstrated between single - and multiple frequency determinations of the right upper limb (R = 35.5 ± 6.2%, P < 0.001; Xc = 2.7 ± 7.6%, P < 0.01), left upper limb difference (R= 33. 9 ± 6.0%, P < 0.001; Xc = 2.8 ± 8.3%, P < 0.01), right lower limb difference (R = 18.6 ± 4.3%, P < 0.001; Xc = 25.8 ± 10.0%, P < 0.001), left lower limb difference (R = 18.0 ± 4.7%, P < 0.001; Xc = 31.8%). Of the results determined with the two BIA methods, the impedance measurements of the limbs and whole body showed a high correlation (RA: R = 0. 950, LA: R = 0. 949, RL: R = 0.899, LL: R = 0.88), and in the agreement test, the impedance values of the upper limbs and whole body also showed strong agreement (ICC > 0.9), but in the Xc, the correlation was weak. In conclusion, it was found that although bioimpedance devices had significantly different characteristics and inconsistent cross sectionally, there was a high population level agreement in the upper and lower extremities in determining segmental resistance value changes. But a large error was found on the trunk. Further studies were needed for reducing the error.

• Proceedings of the KSMRM Conference
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• 2003.10a
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• pp.17-17
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• 2003

목적： 생체 조직에서의 전기임피던스 분포는 생리적 기능에 대하여 풍부한 정보를 가지고 있다. 이러한 전기임피던스 분포는 전기임피던스단층촬영법(EIT)으로 구할 수 있으나 공간해상도가 열악하여 그 사용이 보편화되지 못하고 있다. 기존의 EIT의 한계점을 극복하기 위하여 EIT와 MRI 기술을 결합한 자기공명임피던스단층촬영법(MREIT： Magnetic Resonance Electrical Impedance Tomography)이 최근 제안되었다. MREIT는 영상복원 과정에서 x, y, z 3방향의 자속밀도 벡터를 필요로 하므로 MRI용 자석 내에서 물체를 3차원으로 회전하여 자속밀도 벡터를 구해야 한다. 이러한 3차원 회전은 MREIT가 실제 임상에 적용되는데 있어서 한계점으로 지적되고 있다. 본 논문에서는 물체 회전을 하지 않고 전기임피던스 분포를 얻을 수 있는 새로운 MREIT 방법을 제안하였다. 새로운 MREIT 방법의 원리에 대해서 소개하고 0.3T의 주자장세기를 갖는 연구용 MRI 시스템에서 얻은 MREIT영상을 소개하고자 한다.

• Journal of the Korea Convergence Society
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• v.8 no.2
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• pp.121-126
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• 2017

In this study, we measured the bioelectrical impedance of whole body in various frequency bands by non-invasive method by four electrode method using a portable small impedance measurement system developed to understand the bioimpedance characteristics of intracellular fluid and extracellular fluid components through a skin equivalent model. The measurements were performed on 10 male subjects (mean age $24{\pm}3.0$, body mass index(BMI) $20.3kg/m^2$) for four weeks and the bioimpedances were measured at multi-frequencies (1 kHz, 5 kHz, 50 kHz, 70 kHz, 100 kHz and 500 kHz). Experimental results show that the impedance is the highest in the low frequency range of 1 kHz and the lowest in the high frequency range of 500 MHz. Especially, it was confirmed through experiments that the impedance is rapidly lowered above 50 kHz band. In addition, it was confirmed that similar characteristics to the measured values of the bioimpedance measuring system were obtained in the simulations for understanding the impedance characteristics of the intracellular fluid and the extracellular fluid through the skin equivalent circuit model.

• Journal of IKEEE
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• v.23 no.4
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• pp.1122-1127
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• 2019

In this study, the bio-impedance of the human body is able to obtain a lot of information by monitoring the pathological and physiological conditions of clinical and biological tissues. The four electrode method system for biometrics measured the potential difference between two electrodes and the other two electrodes were used as electrodes for current flow. The newly developed dry gold electrode measured impedance from 1 Hz to 50 kHz and produced reproducible results. To verify the impedance measurement of the dry electrode, the pitting was performed using an equivalent circuit model of the bioelectrode skin, and the effectiveness was demonstrated through modeling. Fixed electrode types have a constant position of the electrodes attached during the measurement, so that a stable measurement can be obtained, thereby minimizing the error.

• Journal of Korea Society of Industrial Information Systems
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• v.19 no.4
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• pp.9-16
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• 2014

Electrode contact resistance is a crucial factor in physiological measurements and can be an accuracy limiting factor to perform electrical impedance measurements. The electrical bio-impedance values can be calculated by the conductivity and permittivity of underlying tissue using implant electrode in human skin. In this study we focus on detecting physiological changes in the human skin layers such as the sebum layer, stratum corneum layer, epidermis layer, dermis layer, subcutaneous fat and muscle. The aim of this paper is to obtain optimal design for implantable electrode at subcutaneous fat layer through the simulation by finite element methods(FEM). This is achieved by evaluating FEM simulations geometrically for different electrodes in length(50 mm, 70 mm), in shape(rectangle, round square, sexangle column), in material(gold) and in depth(22.325 mm) based on the information coming from the subcutaneous fat layer. In bio-impedance measurement experiments, according to electrode shapes and applied voltage, we have ascertained that there was the highest difference of bio-impedance in subcutaneous fat layer. The methodology of simulation can be extended to account for different electrode designs as well as more physical phenomena that are relevant to electrical impedance measurements of skin and their interpretation.

• Journal of Gastric Cancer
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• v.7 no.4
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• pp.228-236
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• 2007

Purpose: We have evaluated changes of body composition for patients that underwent a radical gastrectomy for stomach cancer by the use of available bioelectrical impedance analysis during the first year following surgery. We plan to utilize these findings in nutritional and physiological studies. Materials and Methods: We evaluated clinical changes in body composition in patients using the bioelectrical impedance method (Inbody 4.0, Biospace, Korea), between November 2003 to November 2004. A total of 98 patients agreed to enroll in this study among all of the patients that underwent a radical gastrectomy. Results: The average weight decreased by 6.7%, and 9.4%, within the first and 6 months after surgery, respectively (P<0.01). The fat free mass (FFM) dropped by 4.9% within the first month and there were no more changes after this period (P<0.01). The fat mass (FM) and visceral fat area (VFA) decreased 24.3% and 14.1% within the first 6 months (P<0.01), respectively. The reduction effects for female patients were greater than for male patients for weight, FFM and VFA (P<0.05). The edema index was higher in patients with stage III-IV disease than in patients with stage I-II disease (P<0.05). There were significant differences for Billroth I and Billrothl II patients as compared to patients that underwent an esophagojejunostomy for a reduction of the FM, as measured in the in the 12th month after surgery (27.6%, 22.1%, and 41.2%, respectively; P<0.05). Conclusion: Since nutritional supplementation and an improvement in body weight loss after a radical gastrectomy is significantly related with quality of life, nutritional and physiological studies should be greatly considered. In this study, bioelectrical impedance analysis was very useful in analyzing the diminution of body composition and we hope this study on the nutritional and physiological aspects related to a radical gastrectomy will be useful for later studies.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.11
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• pp.5403-5408
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• 2012

In this paper, we introduce the multiple frequency bio-electrical impedance analysis method for body composition analysis. And then we implement the multiple frequency bio-electrical impedance analysis system. Overall system consists of: multiple frequency alternating current signal generator contained alternating current signal, phase signal detector, voltage signal detector, micro controller, in-out device(key-pad LCD), conductivity electrodes, system power. We explain the architecture of the system and required theory to implement the system. In order to investigate the clinical significance of the body composition data, compare to the data measured by the expert body composition analyzer which provide high reproduction and precision. Finally, experimental results which are the correlation between the measured data show the very high reproduction performance of the body composition analysis in the proposed system.