• Title/Summary/Keyword: 생체적합도

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The Effect of Crystallinity on the Photoluminescence of TiO2 Nanoparticles (결정성에 따른 TiO2 나노입자의 포토루미네선스 영향)

  • Han, Wooje;Park, Hyung-Ho
    • Journal of the Microelectronics and Packaging Society
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    • v.26 no.1
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    • pp.23-28
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    • 2019
  • The Titanium oxide ($TiO_2$) is an attractive ceramic material which shows non-toxic, high refractive index, catalytic activity and biocompatibility, and can be fabricated at a low cost due to its high chemical stability and large anisotropy. $TiO_2$ nanoparticles have been prepared by sol-gel method. The pH of solution can affect the $TiO_2$ crystallinity during the formation of nanoparticles. The prepared nanoparticles were characterized using Fourier transform infrared spectroscopy, scanning electron microscopy, X-ray diffraction, photoluminescence spectroscopy in order to investigate their structural and photoluminescence properties. Through these analysis, the size of $TiO_2$ nanoparticles were found to be smaller than 5 nm. As the crystallinity of the nanoparticles increased, the emission of PL in the 550 nm region increased. Therefore, luminescence characteristics can be improved by controlling the crystallinity of the $TiO_2$ nanoparticles.

Comparison between mechanical properties and biocompatibility of experimental 3D printing denture resins according to photoinitiators (광개시제에 따른 실험용 3D 프린팅 의치상 레진의 기계적 성질과 생체적합성 비교)

  • Park, Da Ryeong;Son, Ju lee
    • Journal of Technologic Dentistry
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    • v.42 no.4
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    • pp.355-361
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    • 2020
  • Purpose: In this study, we added two kinds of photoinitiators (CQ and TPO) to prepare two kinds of denture base resins (Bis-GMA series and UDMA series) for three-dimensional (3D) printing to compare and analyze their mechanical and biological properties and to find the optimal composition. Methods: Control specimens were made using the mold made of polyvinyl siloxane of the same size. Light curing was performed twice for 20 seconds on both the upper and lower surfaces with LED (light emitting diode) light-curing unit (n=10). Experimental 3D printing dental resins were prepared, to which two photoinitiators were added. Digital light processing type 3D printer (EMBER, Autodesk, CA, USA) was used for 3D printing. The specimen size was 64 mm×10 mm×3.3 mm according to ISO 20795-1. The final specimens were tested for flexural strength and flexural modulus, and MTT test was performed. Furthermore, one-way analysis of variance was performed, and the post-test was analyzed by Duncan's test at α=0.05. Results: The flexural strength of both Bis-GMA+CQ (97.12±6.47 MPa) and UDMA+TPO (97.40±3.75 MPa) was significantly higher (p<0.05) in the experimental group. The flexural modulus in the experimental group of UDMA+TPO (2.56±0.06 GPa) was the highest (p<0.05). MTT test revealed that all the experimental groups showed more than 70% cell activity. Conclusion: The composition of UDMA+TPO showed excellent results in flexural strength, flexural modulus, and biocompatibility.

Effect of Cobalt Contents on the Biocompatibility and Corrosion Properties of Fe-31Cr-27Ni-1.6Mo-1.5W-0.26N Alloy (Fe-31Cr-27Ni-1.6Mo-1.5W-0.26N계 초내식성 스테인리스강의 생체적합성 및 부식특성에 미치는 Co함량의 영향)

  • Jang, Soon Geun;Yoo, Young Ran;Nam, Hee Soo;Shim, Gyu Tae;Kim, Jung Gu;Kim, Young Sik
    • Korean Journal of Metals and Materials
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    • v.46 no.4
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    • pp.209-216
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    • 2008
  • Super austenitic stainless steels shows the high PRE (Pitting Resistance Equivalent) number and the good corrosion resistance. This work controlled the Co contents in Fe-31Cr-1.7Mo-27Ni-0.25N alloys to elucidate the effect of cobalt contents on the biocompatibility and corrosion resistance. Increasing Co contents, the hardness of the annealed alloys tends to be reduced. In aged alloys, cobalt decreased the increments of hardness by aging treatment. Cobalt decreased the critical pitting temperature (CPT) in 6% $FeCl_3$ + 1% HCl solution, but improved the anodic polarization behavior in Hanks' balanced salt solution and artificial saliva solution. Repassivation rate in artificial body solutions was improved by increasing cobalt contents, but didn't show the linear relationship to PRE number of the alloys. The experimental alloys showed the non-cytotoxicity because of its high corrosion resistance.

The Mechanical Properties and Biocompatibility of Functionally Graded Coatings(FGC) of Hydroxyapatite(HA) and Metallic Powders - Functionally Gradient Coatings of Thermal Spray in Air- (Hydroxyapatite (HA)와 금속 분말 경사 코팅의 기계적 특성 및 생체 적합성 - 대기 열용사 경사코팅 -)

  • Kim, Eun-Hye;Kim, Yu-Chan;Han, Seung-hee;Yang, Seok-Jo;Park, Jin-Woo;Seok, Hyun-Kwang
    • Korean Journal of Metals and Materials
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    • v.47 no.1
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    • pp.13-20
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    • 2009
  • This work presents functionally graded coatings (FGC) of hydroxyapatite (HA) and metallic powders on Ti-6Al-4V implants using plasma spray coating method. HA has been the most frequently used coating material due to its excellent compatibility with human bones. However, because of the abrupt changes in thermomechanical properties between HA and the metallic implant across an interface, and residual stress induced on cooling from coating temperture to room temperature, debonding at the interface occurs in use sometimes. In this work, FGC of HA and Ti or Ti-alloy powders is made to mitigate the abrupt property changes at the interface and the effect of FGC on residual stress release is investigated by evaluating the mechanical bond strength between the implant and the HA coating layers. Thermal annealing is done after coating in order to crystallize the HA coating layer which tends to have amorphous structure during thermal spray coating. The effects of types and compositional ratio of metallic powders in FGC and annealing conditions on the bond strength are also evaluated by strength tests and the microstructure analysis of coating layers and interfaces. Finally, biocompatibility of the coating layers are tested under ISO 10993-5.

Fabrication of Graphene-modified Indium Tin Oxide Electrode Using Electrochemical Deposition Method and Its Application to Enzyme Electrode (전기화학 증착법을 이용한 그래핀 개질 Indium Tin Oxide 전극 제작 및 효소 전극에 응용)

  • Wang, Xue;Shi, Ke;Kim, Chang-Joon
    • Korean Chemical Engineering Research
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    • v.60 no.1
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    • pp.62-69
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    • 2022
  • Graphene has a large surface area to volume ratio and good mechanical and electrical property and biocompatibility. This study described the electrochemical deposition and reduction of graphene oxide on the surface of indium tin oxide (ITO) glass slide and electrochemical characterization of graphen-modified ITO. Cyclic voltammetry was used for the deposition and reduction of graphene oxide. The surface of graphen-coated ITO was characterized using scanning electron microscopy and energy dispesive X-ray spectroscopy. The electrodes were evaluated by performing cyclic voltammetry and electrochemical impedance spectroscopy. The number of cycles and scan rate greatly influenced on the coverage and the degree of reduction of graphene oxide, thus affecting the electrochemical properties of electrodes. Modification of ITO with graphene generated higher current with lower charge transfer resistance at the electrode-electrolyte interface. Glucose oxidase was immobilized on the graphene-modified ITO and has been found to successfully generate electrons by oxidizing glucose.

Physical Properties and Cytotoxicity of Dental Pit and Fissure Sealants Containing Cerium Oxide Nano Particles(CNPs) (세륨옥사이드나노입자(Cerium Oxide Nano Particles; CNPs)를 첨가한 치면열구전색재의 물리적 특성 및 세포독성)

  • Jeong, Mi-Ae;Kim, Dong-Ae
    • The Journal of the Korea Contents Association
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    • v.22 no.3
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    • pp.586-592
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    • 2022
  • In this study cerium nano particles(CNPs) with 0-4.0 wt% was incorporated to the conventional dental pit and fissure sealant(ConciseTM) to produce new pit and fissure sealant the physical properties and cytotoxicity. The physical properties were measured for polymerizing depth the degree of water absorption and solubility. The cytotoxicity of cell viability was analyzed by MTT assay using immortalized human oral keratinocyte(IHOK). As a result of this preceding study the polymerizing depth was decreased by the increasing of the amount of CNPs. The solubility degree of the sealant added CNPs with 2.0 wt% showed was the lower and the water absorption showed no significantly difference with the control groups(p>0.05). The cytotoxicity test results showed high survival rates in all experimental groups. Therefore, pit and fissure sealant by the addition of CNPs excellent cell viability be produced without weaken the physical property of the cell viability fissure sealant containing CNPs does not weaken physical properties and has no cytotoxic effects biocompatibility. Considering its properties effect of CNPs, further studies are required for distribution technology application.

Osteolysis-Related Bioabsorbable Suture Anchor Fixation in a Medial Collateral Ligament Avulsion Fracture during Total Knee Arthroplasty (슬관절 인공관절 치환술 중 발생한 내측 측부 인대 견열 골절에 대해 생흡수성 봉합 나사못을 이용한 고정 후 발생한 골용해)

  • Huh, Jung-Wook;Park, Man-Jun;Hong, Seong-Hwak;Park, Joon-Hyung
    • Journal of the Korean Orthopaedic Association
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    • v.55 no.6
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    • pp.545-549
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    • 2020
  • Although rare, the treatment options for a medial collateral avulsion fracture during total knee arthroplasty (TKA) range from conservative management using a cast and orthosis to internal fixation using metal screws. Bioabsorbable suture anchors have been used to replace metal fixators with distinct advantages, such as biocompatibility, radiolucency, and unnecessary second removal surgery, but complications, such as osteolysis, have been reported. This paper reports a potential risk of an extensive osteolysis-related suture anchor fixation of a medial collateral ligament (MCL) avulsion fracture during TKA in conjunction with a literature review.

Manufacturing and in vitro Characterization of Composite Drug Delivery System (DDS) (복합재 약물전달 시스템의 제작 및 체외 환경 특성 평가)

  • Chu, Won-Shik;Jeong, Suk-Yong;Park, Jeong-Bin;Ahn, Sung-Hoon;Lee, Jae-Hoon;Chi, Sang-Chul
    • Composites Research
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    • v.21 no.3
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    • pp.18-23
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    • 2008
  • The Rapid Prototyping (RP) technology has advanced in many application areas. In this research, implantable Drug Delivery System (DDS) was fabricated by an RP system, Nano Composite Deposition System (NCDS). The DDS composite consists of 5-fluorouracil (5-FU), as drug particles, and PLGA85/15 as biodegradable polymer matrix. To have larger surface area, the DDS was fabricated in a scaffold shape, and its degradation was tested in vitro environment. Biocompatible Hydroxyapatite (HA) powders were added to the drug-polymer composite in order to control drug release. Test results showed a possibility of controlled release of scaffold DDS over 50 days.

User Authentication Protocol preserving Enhanced Anonymity and Untraceability for TMIS

  • Mi-Og Park
    • Journal of the Korea Society of Computer and Information
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    • v.28 no.10
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    • pp.93-101
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    • 2023
  • In this paper, as a result of analyzing the TMIS authentication protocol using ECC and biometric information proposed by Chen-Chen in 2023, there were security problems such as user impersonation attack, man-in-the-middle attack, and user anonymity. Therefore, this paper proposes an improved authentication protocol that provides user anonymity to solve these problems. As a result of analyzing the security of the protocol proposed in this paper, it was analyzed to be secure for various attacks such as offline password guessing attack, user impersonation attack, smart-card loss attack, insider attack, perfect forward attack. It has also been shown to provided user privacy by guaranteeing user anonymity and untraceability, which must be guaranteed in TMIS. In addition, there was no significant increase in computational complexity, so the efficiency of execution time was achieved. Therefore, the proposed protocol in this paper is a suitable user authentication protocol for TMIS.

Effect of Mulching Material on Growth and Yield of Cucumis melo L. cv. Reticulatus (멀칭재료가 멜론 생육 및 수량에 미치는 영향)

  • Kyu Hoi Lee;Min-Jeong Lee;Ju Hyoung Kim;Young Ho Kim
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2020.12a
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    • pp.67-67
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    • 2020
  • 멜론(Cucumis melo L. cv. Reticulatus)은 다른 과채류에 비해 재배기간이 짧고 수확 시 노동력이 덜 필요로 하는 작물로 고품질 멜론 생산 시 판로 및 가격이 높게 형성되어 농가소득 향상에 적합한 작물이다. 멜론의 국내 시장규모는 1,000억원 정도이며, 일본의 멜론 시장은 4조원으로 40배 정도 큰 시장을 형성하고 있으므로, 수출을 위한 고품질 재배기술 개발이 필요하다. 따라서, 본 연구는 충청북도농업기술원 시험연구포장에서 고온기 근권 환경 최적화를 위한 멀칭 방법을 구명하기 위해 수행하였다. 멜론은 얼스마운틴 PMR 품종을 4월 29일에 120 × 50 cm 로 정식하였으며, 멀칭 처리는 녹색비닐, 검정부직포, 종이멀칭지를 난괴법 3반복으로 각각 피복하였다. 멀칭자재별 생육특성 중 초장은 녹색비닐과 종이멀칭 피복처리에서 각각 148.1 cm, 144.8cm 로 우수하였으며, 엽폭 및 엽장은 유의성 있는 차이가 나타나지 않았다. 생체중은 종이멀칭지로 피복한 처리에서 716.7 g plant-1 로 가장 우수하게 나타났다. 과특성 중 과직경은 녹색비닐과 종이멀칭 피복처리에서 각각 16.1 cm로 우수하였으며, 과중은 종이멀칭지로 피복한 처리에서 2,235 g plant-1 로 가장 우수하게 나타났다. 이처럼 멀칭재료에 따른 생육특성 차이를 확인하였으며, 이러한 적정 멀칭자재 선발을 통해 여름철 고온기 근권 환경 최적화를 통한 멜론 수량 및 품질향상에 기여할 것으로 판단된다.

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