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http://dx.doi.org/10.5392/JKCA.2022.22.03.586

Physical Properties and Cytotoxicity of Dental Pit and Fissure Sealants Containing Cerium Oxide Nano Particles(CNPs)  

Jeong, Mi-Ae (강원대학교 치위생(학)과)
Kim, Dong-Ae (여주대학교 치위생(학)과)
Publication Information
The Journal of the Korea Contents Association / v.22, no.3, 2022 , pp. 586-592 More about this Journal
Abstract
In this study cerium nano particles(CNPs) with 0-4.0 wt% was incorporated to the conventional dental pit and fissure sealant(ConciseTM) to produce new pit and fissure sealant the physical properties and cytotoxicity. The physical properties were measured for polymerizing depth the degree of water absorption and solubility. The cytotoxicity of cell viability was analyzed by MTT assay using immortalized human oral keratinocyte(IHOK). As a result of this preceding study the polymerizing depth was decreased by the increasing of the amount of CNPs. The solubility degree of the sealant added CNPs with 2.0 wt% showed was the lower and the water absorption showed no significantly difference with the control groups(p>0.05). The cytotoxicity test results showed high survival rates in all experimental groups. Therefore, pit and fissure sealant by the addition of CNPs excellent cell viability be produced without weaken the physical property of the cell viability fissure sealant containing CNPs does not weaken physical properties and has no cytotoxic effects biocompatibility. Considering its properties effect of CNPs, further studies are required for distribution technology application.
Keywords
Physical Properties; Cerium Oxide Nano Particles(CNPs); Cytotoxicity; Dental Pit and Fissure Sealant;
Citations & Related Records
Times Cited By KSCI : 4  (Citation Analysis)
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