• Proceedings of the Korea Water Resources Association Conference
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• 2018.05a
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• pp.43-43
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• 2018

수생태계는 다른 여러 생태계 중에서 가장 위험에 처해있으며, 기후변화로 인한 수온, 수문 수질의 변화는 수생태계와 담수 생물다양성에 가장 큰 영향을 미치는 요인 중 하나이다. 본 연구에서는 생물 생태학적으로 변화하는 세계적인 물 관리 패러다임에 따라 한강유역에서의 미래 수생태계 평가를 수행하였다. 본 연구의 목적은 수생태 건강성 관측자료와 수질자료, SWAT 모형을 이용하여 미래 기후변화에 따른 한강유역의 수생태를 평가하는 것이다. 본 연구에서 선정한 수생태계 건강성 조사자료로 국립환경과학원에서 8년간(2008년~2015년) 봄과 가을 2차례에 걸쳐 모니터링 한 부착돌말류(TDI), 저서형 대형무척추동물(BMI), 어류(FAI)에 대한 수생태 등급자료 및 해당 지점에 대한 수온 및 수질자료를 이용하였다. 수집한 결과를 DB(T-N, $NH_4N$, $NO_3N$, T-P, PO4P)에 대한 수생태 등급의 상관성을 분석하고 수온 수질인자에 따른 수생태 등급을 나타내어 미래 기후변화에 따른 수생태 건강성 평가 및 예측을 실시하고자 하였다. Soil and Water Assessment Tool (SWAT) 모형은 유역의 신뢰성 있는 유역 수문, 수질 모의 및 기후변화 영향평가를 위하여 활용되었다. SWAT 모형을 이용하여 한강유역의 다목적댐(3개), 발전용댐(1개), 다기능보(3개) 운영을 고려하였고, 237개의 표준유역으로 분할한 뒤 수문 및 수질 모의를 수행하였다. 모형의 적용성 평가를 위해 댐 및 보의 유입량, 증발산량, 토양수분, 지하수위, SS, T-N, T-P에 대하여 보정(2005~2009) 및 검증(2010~2015)을 수행하였다. 기후변화에 따른 수문, 수질 및 수생태 평가를 위해 기상청의 HadGEM3-RA RCP 4.5와 8.5 시나리오를 적용하였으며, 기준년(1975-2005)년에 대해 2020s(2010-2039), 2050s(2040-2069), 2080s(2070-2099)의 수생태를 평가하였다.

• The Korean Journal of Applied Statistics
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• v.24 no.4
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• pp.623-631
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• 2011

A major goal of time-course microarray data analysis is the detection of groups of genes that manifest similar expression patterns over time. The corresponding numerous cluster algorithms for clustering time-course microarray data have been developed. In this study, we proposed a clustering method based on the primary pharmacokinetic parameters in the pharmacokinetics study for assessment of pharmaceutical equivalents between two drug products. A real data and a simulation data was used to demonstrate the usefulness of the proposed method.

• Journal of the Korean Society for Marine Environment & Energy
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• v.17 no.2
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• pp.153-165
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• 2014

Carbon dioxide capture and storage (CCS) technology is recognizing one of method responding the climate change with reduction of carbon dioxide in atmosphere. In Korea, due to its geological characteristics, sub-seabed geological $CO_2$ storage is regarded as more practical approach than on-land storage under the goal of its deployment. However, concerns on potential $CO_2$ leakage and relevant acidification issue in the marine environment can be an important subject in recently increasing sub-seabed geological $CO_2$ storage sites. In the present study effect data from literatures were collected in order to conduct an effect assessment of elevated $CO_2$ levels in marine environments using a species sensitivity distribution (SSD) various marine organisms such as microbe, crustacean, echinoderm, mollusc and fish. Results from literatures using domestic species were compared to those from foreign literatures to evaluate the reliability of the effect levels of each biological group and end-point. Ecological effect guidelines through estimating level of pH variation (${\delta}pH$) to adversely affect 5 and 50% of tested organisms, HC5 and HC50, were determined using SSD of marine organisms exposed to the $CO_2$-induced acidification. Estimated HC5 as ${\delta}pH$ of 0.137 can be used as only interim quality guideline possibly with adequate assessment factor. In the future, the current interim guideline as HC5 of ${\delta}pH$ in this study will look forward to compensate with supplement of ecotoxicological data reflecting various trophic levels and indigenous species.

• Journal of Wetlands Research
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• v.11 no.3
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• pp.1-8
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• 2009

The groundwater dependent ecosystem associated with a natural stream is the area where mixing and exchange of surface water and groundwater occurs due to large chemical and hydraulic gradients. Surface-groundwater interactions play an important role in biogeochemical processes in groundwater dependent ecosystems and make this area a hydro-ecological hot spot. The objective of this study is to characterize the groundwater dependent ecosystem in a natural stream where nitrate contamination of stream water is observed by means of hydrogeological, chemical, and biological methods. In this study, vertical flow exchange(hyporheic flow) rates between stream and groundwater were estimated based on vertical hydraulic gradients measured at mini-piezometers of various depths. To investigate the biological natural attenuation potential, biological analyses using polymerase chain reaction(PCR)-cloning methods were performed in this study. Results show that the veritical hyporheic water fluxes affect nitrate concentrations and bacterial densities in groundwater dependent ecosystems to some degree. Also, denitrifying bacteria were identified in hyporheic soils, which may support the biodegradation potential of the groundwater dependent ecosystems under certain conditions.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.17 no.1
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• pp.59-73
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• 2019

A decontamination technology for radioactive liquid wastes was newly developed and hypothetically applied to the liquid waste management system (LWMS) of the nuclear power plant (NPP) to evaluate its decontamination efficacy for the purpose of the fundamental reduction of spent resins. The basic principle of the developed technology is to convert major radionuclide ions in the liquid wastes into inorganic crystal minerals via chemical or biological techniques. In a laboratory batch experiment, the biological method selectively removed more than 80% of cesium within 24 hours, and the chemical method removed more than 95% of cesium. Other major nuclides (Co, Ni, Fe, Cr, Mn, Eu), which are commonly present in nuclear radioactive liquid wastes, were effectively scavenged by more than 99%. We have designed a module including the new technology that could be hypothetically installed between the reverse osmosis (R/O) package and the organic ion-exchange resin in the LWMS of the APR1400 reactor. From a technical evaluation for the virtual installation, we found that more than 90% of major radionuclides in the radioactive liquid wastes were selectively removed, resulting in a large volume reduction of spent resins. This means that if the new technology is commercialized in the future, it could possibly provide drastic cost reduction and significant extension of the life of resins in the management of spent resins, consequently leading to delay the saturation time of the Wolsong repository.

• Proceedings of the Korea Water Resources Association Conference
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• 2010.05a
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• pp.1706-1709
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• 2010

Sewerage Treatment Plants(STPs) are complexes systems in which a range of physical, chemical and biological processes occur. Since Activated Sludge Model(ASM) No.1 was published, a number of new mathematical models for simulating biological processes have been developed. However, these models have disadvantages in cost and simplicity due to the laboriousness and tediousness of their procedures. One of the major difficulties of these mathematical model based tools is that the field-operators mostly don't have the time or the computer-science skills to handle there models, so it mainly remains on experts or special engineers. In order to solve these situations and help the field-operators, the $KM^2BM$(K-water & More-M Mass Balance Model) based on the dynamic-mass balance model was developed. This paper presents $KM^2BM$ as a simulation tools for STPs design and optimization. This model considers the most important microbial behavioral processes taking place in a STPs to maximize potential applicability without increasing neither model parameter estimation nor wastewater characterization efforts.

• Korean Journal of Ichthyology
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• v.29 no.1
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• pp.41-51
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• 2017

To understand the application in farm for the fish aquaculture, we investigated biological and pathological traits on red sea bream Pagrus major which were reared in each copper-alloy net cage and the synthetic fiber net cage for 9 months. Two groups of cage were made and set in Yokji-eup, Tongyoung, Gyeongsangnam-do in size of 25 m in diameter and 10 m of depth. Survival rate of the red sea bream in the rearing copper-alloy net cage and synthetic fiber cage showed 99.75% and 99.70% respectively, there was no significant difference. Daily weight growth rate in each net was shown to 2.13 g/day and 1.65 g/day. Health analysis by blood composition analysis showed a favorable result in the copper-alloy net cage rather than in the synthetic fiber net. Bioaccumulation of heavy metal such as Cu and Zn especially in gonad was higher than other organ. Bioaccumulation of Cu and Zn in the muscle was lower compared to the permitted standard for food safety. Pathogenic infection test discovered Microcotyle tai for parasite, V. alginolyticus and other five species for bacteria. But there was a little bit difference of bacteria infection in copper-alloy net cage and copper-alloy net cage is expected to be has antibacterial effect. Thus, copper-alloy net cage can be applied to farm considering its system stability, recycling, antibiosis and food safety.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2018.06a
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• pp.22-22
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• 2018

의료기기는 사용목적과 사용 시 인체에 미치는 잠재적 위해성의 정도에 따라 4개의 등급으로 분류하며, 두 가지 이상의 등급에 해당되는 제품의 경우에는 가장 높은 등급으로 분류하게 된다. 의료기기 품목허가를 위해서는 기술문서를 작성하여야 하며, 이를 위해서는 기술문서 심사를 신청하는 절차를 이해하여야 한다. 의료기기 기술문서란 의료기기의 성능과 안전성 등 품질에 관한 자료로서 해당 품목의 원자재, 구조, 사용목적, 사용방법, 작용원리, 사용 시 주의사항, 시험규격 등이 포함되는 문서를 말하며, '의료기기 허가 신청서'와 '첨부자료(임상시험자료 포함)'로 구성되어 있다. 의료기기 품목허가 시 제출되는 기술문서를 통하여 해당 의료기기의 안전성 및 성능이 충분히 입증되어야 하며, 인체 삽입되는 표면처리 임플란트를 포함한 인체 접촉 의료기기의 안전성의 경우 '의료기기의 생물학적 안전에 관한 공통 기준규격'에 따라 평가 후 제조 수입품목 허가를 진행해야 한다. 또한 성능의 경우는 해당 규격 또는 자사의 기준 및 시험방법에 따른 성능에 관한 자료, 물리 화학적 특성에 관한 자료를 통하여 평가되어야 하며, 기허가 인증된 제품에 한 번도 사용되지 않은 원재료 또는 적용부위 및 적용방법이 달라 안전성 및 유효성 확인이 필요한 경우 임상시험에 관한 자료가 요구될 수 있다. 본 발표에서는 이러한 인체 삽입용 표면처리 임플란트의 전반적인 인허가 절차에 대해서 안내하고자 한다.

• Journal of Environmental Impact Assessment
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• v.11 no.4
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• pp.259-269
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• 2002

보전전략은 규모가 큰 지역을 설정하여야 하는 데 그 이유는 광역보전지역은 다양한 생물지리학적인 분포를 포함할 수 있기 때문이다. 이런 관점에서 본 보고서는 우리 나라의 다섯 개의 중요한 생태계에 대하여 기술하였다. 다섯 개의 생태계는 산림생태계, 담수생태계, 연안 및 해양 생태계와 도서생태계 그리고 비무장지대생태계이다. 각각의 생태계 보전전략에 대해 물리적인 측면과 생물지리적 측면에서 기술되었으며 생태계 보전방안은 생태계의 기능과 가치뿐만 아니라 자연시스템을 유지하고 복원하는 데 매우 유리하다. 생태계 보전을 위해 1) 지역주민에게 인센티브를 제공하고, 2) 연구와 교육 및 홍보의 기능을 강화하며, 3) 지역정보와 기술을 상호 교환하고, 4) 국제협력 증진을 도모, 5) 보전지역을 조성하기 위한 예산확보를 제안하였다.

• Korean Journal of Psychosomatic Medicine
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• v.9 no.2
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• pp.182-193
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• 2001

The purpose of this study is to evaluate correlation of adolescent eating attitude and psychological factors which might influence the eating attitude such as depression, aggression and impulsiveness. The author also tried to identify relationship between adolescent eating attitude and biological factors such as serum cholesterol level and triglyceride level. Two hundred and forty one female high school students without physical disorder were selected as study subjects. For the study, Eating Attitude Test-26KA (EAT -26KA), Beck Depression Inventory (BDI) -Korean version, Barrat Impulsiveness scale (BIS) -Korean version, and Buss-DurKee Hostility Inventory (BDHI) -Korean version were used. Serum cholesterol level and triglyceride level were also investigated. For the purpose of identifying factors which could influence eating attitude of adolescence, stepwise multiple linear regression analysis was done. Total score of BDHI could be most significant factor to explain eating attitude, and BDI, serum cholesterol/triglyceride level be second, third position respectively. But, BIS was not significant predicting parameter. The contributing portion of these factors to explain eating behavior was 25.9%.