• Title/Summary/Keyword: 생물이동경로

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High dose of QX-314 produces anti-nociceptive effect without capsaicin in rats with inflammatory TMJ pain

  • Yang, Kui-Ye;Kim, Min-Su;Kim, Eun-Kyung;Kong, Mi-Sun;Ahn, Jong-Soo;Lee, Jong-Hun;Ju, Jin-Sook;Ahn, Dong-Kuk
    • International Journal of Oral Biology
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    • v.38 no.4
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    • pp.135-140
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    • 2013
  • The present study investigated the effects of QX-314 on inflammatory pain of the temporomandibular joint (TMJ). Experiments were carried out on male Sprague-Dawley rats weighing 220-280 g. Under anesthesia, the TMJ of each animal was injected with $50{\mu}L$ of formalin (5%). The number of noxious behavioral responses, including rubbing or scratching of the facial region including the TMJ area, was recorded over 9 sequential 5 min intervals for each animal. Although 2.5% QX-314 did not affect formalin-induced nociceptive behavior, administration of 5% QX-314 with formalin significantly decreased the number of scratches produced by the formalin injection. Co-administration of capsaicin, a TRPV1 agonist, with 2.5% QX-314 produced significant anti-nociceptive effects whereas 2.5% QX-314 alone did not. However, the co-administration of capsaicin did not enhance the anti-nociceptive effects in the 5% QX-314-treated rats. Moreover, the co-administration of capsazepine, a TRPV1 antagonist, did not attenuate anti-nociceptive effects in the 5% QX-314-treated rats. These findings suggest that TRPV1 is effective in the transport of low but not high doses of QX-314. Moreover, a high dose of QX-314, which is not mediated by peripheral TRPV1 activity, may be viable therapeutic strategy for inflammatory pain in the TMJ.

Abundance and Occupancy of Forest Mammals at Mijiang Area in the Lower Tumen River (두만강 하류 밀강 지역의 산림성 포유류 풍부도와 점유율)

  • Hai-Long Li;Chang-Yong Choi
    • Korean Journal of Environment and Ecology
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    • v.37 no.6
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    • pp.429-438
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    • 2023
  • The forest in the lower Tumen River serves as an important ecosystem spanning the territories of North Korea, Russia, and China, and it provides habitat and movement corridors for diverse mammals, including the endangered Amur tiger (Panthera tigris) and Amur leopard (Panthera pardus). This study focuses on the Mijiang area, situated as a potential ecological corridor connecting North Korea and China in the lower Tumen River, playing a crucial role in conserving and restoring the biodiversity of the Korean Peninsula. This study aimed to identify mammal species and estimate their relative abundance, occupancy, and distribution based on the 48 camera traps installed in the Mijiang area from May 2019 to May 2021. The results confirmed the presence of 18 mammal species in the Mijiang area, including large carnivores like tigers and leopards. Among the dominant mammals, four species of ungulates showed high occupancy and detection rates, particularly the Roe deer (Capreolus pygargus) and Wild boar (Sus scrofa). The roe deer was distributed across all areas with a predicted high occupancy rate of 0.97, influenced by altitude, urban residential areas, and patch density. Wild boars showed a predicted occupancy rate of 0.73 and were distributed throughout the entire area, with factors such as wetland ratio, grazing intensity, and spatial heterogeneity in aspects of the landscape influencing their occupancy and detection rates. Sika deer (Cervus nippon) exhibited a predicted occupancy rate of 0.48, confined to specific areas, influenced by slope, habitat fragmentation diversity affecting detection rates, and the ratio of open forests impacting occupancy. Water deer (Hydropotes inermis) displayed a very low occupancy rate of 0.06 along the Tumen River Basin, with higher occupancy in lower altitude areas and increased detection in locations with high spatial heterogeneity in aspects. This study confirmed that the Mijiang area serves as a habitat supporting diverse mammals in the lower Tumen River while also playing a crucial role in facilitating animal movement and habitat connectivity. Additionally, the occupancy prediction model developed in this study is expected to contribute to predicting mammal distribution within the disrupted Tumen River basin due to human interference and identifying and protecting potential ecological corridors in this transboundary region.

Microbial Diversity in Three-Stage Methane Production Process Using Food Waste (음식물 쓰레기를 이용한 3단계 메탄생산 공정의 미생물 다양성)

  • Nam, Ji-Hyun;Kim, Si-Wouk;Lee, Dong-Hun
    • Korean Journal of Microbiology
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    • v.48 no.2
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    • pp.125-133
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    • 2012
  • Anaerobic digestion is an alternative method to digest food wastes and to produce methane that can be used as a renewable energy source. We investigated bacterial and archaeal community structures in a three-stage methane production process using food wastes with concomitant wastewater treatment. The three-stage methane process is composed of semianaerobic hydrolysis/acidogenic, anaerobic acidogenic, and strictly anaerobic methane production steps in which food wastes are converted methane and carbon dioxide. The microbial diversity was determined by the nucleotide sequences of 16S rRNA gene library and quantitative real-time PCR. The major eubacterial population of the three-stage methane process was belonging to VFA-oxidizing bacteria. The archaeal community consisted mainly of two species of hydrogenotrophic methanogen (Methanoculleus). Family Picrophilaceae (Order Thermoplasmatales) was also observed as a minor population. The predominance of hydrogenotrophic methanogen suggests that the main degradation pathway of this process is different from the classical methane production systems that have the pathway based on acetogenesis. The domination of hydrogenotrophic methanogen (Methanoculleus) may be caused by mesophilic digestion, neutral pH, high concentration of ammonia, short HRT, and interaction with VFA-oxidizing bacteria (Tepidanaerobacter etc.).

The Analysis of Chemistry's Image in Daily newspaper on '2006, the Year of Chemstry' (2006년 '화학의 해'의 언론매체 속 화학 이미지 분석)

  • Shin, Sunyoung;Cho, Mijoo;Park, Jongseok
    • Journal of Science Education
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    • v.32 no.1
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    • pp.47-60
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    • 2008
  • The Ministry of Science and Technology has been planning various events and carrying them out as the effort for promotion and popularization of science. The ministry has made followings: i)Science culture year, 2004 ii) Physics year, 2006 iii)Chemistry year, 2007 iv)Biology year, 2008. Especially, in 2006 the ministry held various exhibitions and contests about chemistry. The science play "Oxygen" had been presented in the whole country, 2006. From 2006 to 2007 the moving science museum had been displayed many times in the whole country. The national broadcast media KBS made a special program and televised several times to commemorate the year of chemistry. Like that in 2006 the chemistry approached to general people. In these surroundings, we wondered how chemistry was expressed in daily newspaper and how the general public accepted chemistry in the year of chemistry, 2006. So we selected four daily newspaper and researched descriptions about chemistry then analyzed the image of chemistry in that descriptions. When we research, we first selected 5 words of high frequency. On the internet research engine we used these 5 words and searched descriptions. We read and sorted descriptions which were more connected to chemistry. Finally we analyzed the images of descriptions(affirmative or negative) and character. The chemistry's image on newspaper descriptions influences people greatly. Because that is the easiest channel.

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Corridor and Network Analyses of Forest Bird Habitats in a Metropolitan Area of South Korea (수도권 지역 산림성 조류 서식지의 통로와 연결망 분석)

  • Kang, Wanmo;Park, Chan-Ryul
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.17 no.3
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    • pp.191-201
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    • 2015
  • Measuring and mapping connectivity among habitats is a key component of sustainable urban planning and design process. In this study, we examined how functional corridors connect forest bird habitats in a metropolitan area of Korea using graph theory-based techniques. High-quality forest habitat was defined as a function of forest cover, presence of residential areas, and road networks. We then constructed a network of high-quality forest habitats using the FunConn (functional connectivity) tools, and computed metrics ($T_i$) of patch importance based on the minimum ($Q_1$) and the 25th percentile ($Q_{25}$) rank least-cost distance values. We investigated the relative influence of two values of patch importance on forest bird species richness. As a result, the patch importance index based on the $Q_{25}$ effective distance threshold was most positively correlated with species richness (P < 0.001) after controlling for the area effect. Thus, using the $Q_{25}$ effective distance threshold, we mapped not only the locations of important habitat patches and functional corridors, but also the network backbone of forest bird habitats. The network developed in this study can help guide urban planning for biodiversity conservation.

Tidal Flat Aspects of Yellow Sea Area and Conservation for Migratory Birds (서해안 갯벌 현황과 철새에 대한 보전 방안)

  • 이시완;제종길;이한수
    • Korean Journal of Environment and Ecology
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    • v.17 no.3
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    • pp.295-303
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    • 2003
  • The tidal flat area of south and west coast consists of 2.4% of total land area of Korea. About 83% of tidal flat is located at the west coast, and the remaining tidal flat is located at the south coast. This tidal flat is also divided for administrative regions which are Gyeonggi Province(35.1%), Chungnam Province(12.7%) Jeonbuk Province(4.7%), Jeonnam Province(44.0%) and Gyeongnam Province(3.5%). The tidal flat of west coast of Korea is one of the most important stopover site for shorebirds on the East Asia-Australia Flyway. The tidal flat is used for feeding and resting place by migratory shorebirds. Generally, waterbirds including migratory shorebirds are considered as key species to show the superiority of wetland. By the criteria of Lamsar Convention in the basis of waterbird, at least 14 coastal wetlands in Korea have to be internationally important wetlands. The factors to affect the distribution of shorebirds at the certain tidal flat are closely related with 1) the distribution of benthic invertebrates, potential prey of shorebirds 2) the availability of roosting site 3) the size of tidal flat 4) the intensity of human disturbance. In this paper, we summarized the regional status of tidal flat of Korea and its conservation methods related with migratory waterbirds.

Measurement of and Changes in L-carnitine Levels in Developing Cucumber Cotyledon (오이 떡잎의 발달 과정에서 carnitine의 검출과 변화)

  • Cha, Hyeon Jeong;Kim, Dae-Jae
    • Journal of Life Science
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    • v.29 no.4
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    • pp.421-427
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    • 2019
  • Mobilization of storage lipids is critical for the germination of oil seeds, as they supply carbon and energy until photosynthesis commences in cotyledons. In this study, we determined the levels of plant carnitine and associated changes in these levels from seed germination to cotyledon senescence. We also examined changes in the content of unsaturated fatty acids throughout seedling development. Carnitine levels peaked on day 3 at 14.5 nM in cotyledons and decreased sharply to 7.2 nM on day 4. On development day 3 carnitine levels were maintained at around 3 nM until day 7. The unsaturated fatty acid content dropped by half at the same time as carnitine peaked (day-3), and storage lipids were almost depleted by day 5. Thereafter, carnitine was hardly detected until the second stage of cotyledon senescence, at which stage the carnitine content was 6.8 nM, similar to that on day 4 at the time of fatty acid depletion in the cotyledons. Unsaturated fatty acids levels remained constant in green cotyledons but slightly increased in the senescing cotyledons. The latter can be explained by intracellular breakdown of membrane lipids. This is the first such discovery in developing cotyledons and may offer clues regarding other roles of the acetyl unit transport system in plants. The expression of BOU was closely associated with carnitine metabolism during seed germination and cotyledon development. The results provide support for the possibility of carbon re-routing during the glyoxylate cycle in the supply of energy for early germination and development.

Tephrostratigraphy and Paleoenvironments of Marine Core in the Kita-Yamato Trough, East Sea/Japan Sea (동해 키타-야마토 해곡에서 채취된 시추코아의 테프라층서와 고환경)

  • Chun Jong-Hwa;Cheong Daekyo;Han Sang-Joon;Huh Sik;Yoo Hai-Soo
    • Economic and Environmental Geology
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    • v.39 no.1 s.176
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    • pp.83-93
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    • 2006
  • The Kita-Yamato Trough is characterized by a SW-NE trending narrow graben between the Yamato Bank and the Kita-Yamato Bank in the central East Sea/Japan Sea (ES/JS). Core 20EEZ-1 was obtained in the flat summit of a small ridge from the southwest Kita-Yamato Trough. The sedimentation was mainly controlled by the supply of hemipelgic sediments and substantial tephras from explosive volcanic eruptions of the Quaternary volcanoes. The aim of this study is to reconstruct the tephrostratigraphy from the marine sediments collected from the Kita-Yamato Trough and to provide the atmosphere and ocean conditions during the explosive volcanic eruptions. According to the detailed tephrostratigraphy and lithofacies records, the core sediments were deposited during the last marine isotope stage (MIS) 7. The core consists of four lithofacies, idetified as, oxidized mud (OM), crudely laminated mud (CLM) and bioturbated mud (BM), interbedded with coarse-grained tephra (TP). The major element geochemistry and stratigraphic positions of seven tephra layers suggest that they originated from the Aira caldera in Kyushu area among the Japanese islands (AT tephra; 29.24 ka), unknown submarine volcano in the south Korea Plateau (SKP-I; MIS 3, SKP-II; MIS 4, SKP-IV; boundary between MIS 6 and MIS 5e, SKP-V; MIS 6, respectively), and the Baegdusan volcano in the Korean Peninsula (B-KY1; ca. 130 ka, B-KY2; ca. 196 ka). The absence of tephras originated trom Ulleung Island in core 20EEZ-l suggest that the tephras had not been transported into the Kita-Yamato Trough by atmosphere conditions during the eruptions. On the other hand, the B-KYI and the B-KY2 tephras derived from the Baegdusan volcano were founded in the Kita-Yamato Trough by a presence of prevailing westerly winds during the eruptions. Furthermore, the SKP tephras were characterized by the transport across the air-water interface, causing quickly thrust of raising eruption plumes from subaqueous explosive eruptions. Surface currents may play an important role in controlling the distribution patterns of the SKP tephras to distal areas. The tephrostratigraphic study in the Kita-Yamato Trough provides the important chronostratigraphic marker horizons and the detailed atmosphere and ocean conditions during the explosive eruptions.

Improvements in the Marine Environmental Survey on Impact of Seawater Qualities and Ecosystems due to Marine Sand Mining (바다모래 채취 시 해수 수질 및 생태계 영향에 대한 해양환경조사 개선 방안)

  • Kim, Yeong-Tae;Kim, Gui-Young;Jeon, Kyeong-Am;Eom, Ki-Hyuk;Kim, In-Chul;Choi, Bo-Ram;Kim, Hee-Jung;Kim, Jin-Min
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.20 no.2
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    • pp.143-156
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    • 2014
  • We reviewed investigation status on turbidity plume in the statement of marine environmental survey(2008 to 2012) associated with marine sand extraction projects. The survey statement from seven marine sand extraction sites (extraction area of Southern EEZ, extraction area of Western EEZ, relocation zone in the Western EEZ, sea area under jurisdiction of Taean-gun, sea area under jurisdiction of Ansan City, and two discrete sea areas under jurisdiction of Ongjin-gun) in the nearshore and offshore of Korea showed that in situ observations were carried out for the dispersion and transport of suspended sediments on two areas (One is a extraction area in the EEZs, the other is an area of coastal sites). However, sampling station and range have not been selected considering physical, geographical factors (tide, wave, stratification, water depth, etc.) and weather conditions (wind direction and velocity, fetch, duration, etc). Especially turbidity plumes originating from three sources, which include suspended sediments in overflow(or overspill) discharged from spillways and reject chutes of dredging vessel, and resuspended sediments from draghead at the seabed, may be transported to a far greater distance outside the boundary of the extraction site and have undesirable impacts on the marine environment and ecosystem. We address that behaviour of environmental pollutants such as suspended solids, nutrients, and metals should be extensively monitored and diagnosed during the dispersion and transport of the plume. Finally we suggest the necessity to supplement the current system of the sea area utilization consultation and establish the combined guidelines on marine sand extraction to collect basic data, to monitor cumulative effects, and to minimize environmental damages incurred by the aftermath of sand extraction.

OECD High Production Volume Chemicals Program: Ecological Risk Assessment of Copper Cyanide (대량생산화학물질 초기위해성평가: 시안화구리의 초기 생태위해성평가)

  • Baek, Yong-Wook;Kim, Eun-Ju;Yoo, Sun-Kyoung;Ro, Hee-Young;Kim, Hyun-Mi;Eom, Ig-Chun;Kim, Pil-Je
    • Korean Journal of Ecology and Environment
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    • v.44 no.3
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    • pp.272-279
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    • 2011
  • Copper cyanide is a chemical produced in large quantities with 2,500 tonnes being produced in 2006. It is mainly used for electroplating copper, particularly alkali-Cu plate and brass plating. The purpose of this study is to reassess the physicochemical properties and environmental fate of copper cyanide based on reliable data and and to conduct an ecotoxicity test according to the OECD test guidelines as an initial environmental risk assessment (need to state where this was done). Metal containing inorganic substances are not subject to degradation, biodegradation or hydrolysis. Aquatic toxicity tests of copper cyanide were conducted according to OECD test guideline 201, 202 and 203 for green algae, daphnia, and fish, respectively. The following acute toxicity test results were obtained for aquatic species: 0.089 mg $L^{-1}$ (Algae, 72 Hr-$EC_{50}$); 0.21 mg $L^{-1}$ (flea, 48 Hr-$LC_{50}$); 0.62 mg $L^{-1}$ (Fish, 96 Hr-$ErC_{50}$). The chemical possesses properties indicating a hazard for the aquatic environment (acute toxicity in fish, daphnia and algae below 1.0 mg $L^{-1}$). As a result of this study, copper cyanide has become a candidate for detailed risk assessment. Countries that produce this chemical in significant quantities are recommended to perform specific assessments.