• Title/Summary/Keyword: 생명

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Estimation of Variance Component on Swine Economic Traits using Multivariate Maternal Animal Model (다변량 모체효과 모형을 이용한 돼지 경제형질의 분산성분 추정)

  • Park, Jong-Won;Kim, Byeong-Woo;Kim, Si-Dong;Jang, Hyeon-Ki;Jeon, Jin-Tae;Kong, Il-Keun;Lee, Jung-Gyu
    • Journal of agriculture & life science
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    • v.44 no.2
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    • pp.29-38
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    • 2010
  • This study looked into estimation of variance component over swine's economic traits by multiple animal model and maternal effect model using on-farm test data of total 31,455 swine of Duroc, Landrace and Yorkshire species that were born between 2000 and 2008. Heritability by estimated additive genetic effect showed higher than one by maternal genetic effect using multivariate maternal animal model in each trait examined by each breed and most heritability when considering only additive genetic effect in multiple traits animal model was estimated to be higher than one by estimated additive genetic effect in multivariate maternal animal model. In correlation between breeding value by estimated maternal genetic effect and phenotypic value using multivariate maternal animal model, rank correlation and simple correlation of breeding value and phenotypic value by maternal genetic effect also showed low positive correlation or strong negative correlation, which can be considered that if correlation with phenotype were increased properly considering maternal genetic effect in each trait by each breed, even better improvement could be promoted.

Uptake and Carry-over of Procymidone Residues to Non-target Succeeding Crop from Applied on Preceding Crop (연작으로 인한 토양잔류 Procymidone의 비의도적 후작물 흡수이행)

  • Kwak, Se-Yeon;Lee, Sang-Hyeob;Sarker, Aniruddha;Kim, Hyo-Young;Shin, Byung-Gon;Kim, Jang-Eok
    • Korean Journal of Environmental Agriculture
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    • v.40 no.3
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    • pp.203-210
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    • 2021
  • BACKGROUND: Pesticides can persist in soil due to multiannual uses. To decrease the concerns for potential carry-over of such residues from treated soil during preceding crop cultivation to non-target crops grown in rotation, an uptake study of procymidone was conducted under the actual cultivation conditions in Korea. METHODS AND RESULTS: Procymidone was sprayed twice by foliar application with recommended and double dose according to the safe use guidelines for Korean cabbage up to 14 days before harvest. Arable land was kept fallow for 4 days after harvesting Korean cabbage, and spinach was cultivated as a succeeding crop. Initial residues in soil were 5.670-14.175 mg/kg that were degraded to 3.098-4.555 mg/kg until harvest of Korean cabbage, and then persisted at 1.026-1.300 mg/kg by spinach harvest. Procymidone residues in edible part of succeeding crops from soil uptake were in range of 0.020-0.048 mg/kg for recommended dose and 0.055-0.116 mg/kg for double dose. Root concentration factor (RCF) values of procymidone at different concentration ranged from 0.053 to 0.123, and translocation factor (TF) ranged from 0.176 to 0.768 for spinach. The value of TF was higher than RCF, indicating that the capability of translocation to shoot was relatively higher than that of root uptake and accumulation. CONCLUSION: Procymidone applied on Korean cabbage can be carried-over to spinach and detected at a level similar to MRL (0.05T mg/kg). Therefore, this study suggests a follow-up study for establishment of plant back interval (PBI) of succeeding crops reflecting the actual agricultural conditions as this study.

Anti-tumor Effects of Codonopsis Lanceolata Extracts on Human Lung and Ovarian Cancer (산지별 더덕 추출물의 폐암 및 난소암에 대한 항암 효능)

  • Cho, Young-Rak;Kim, Soo Hyeon;Yoon, Hyun Jae;Hong, Sam Yeol;Ko, Hee-Young;Park, Eun-Hee;Kim, Myoung-Dong;Seo, Dong-Wan
    • Food Engineering Progress
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    • v.15 no.1
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    • pp.1-5
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    • 2011
  • Codonopsis lanceolata L. (Campanulaceae) has long been used in traditional Korean medicine to treat bronchitis, cough, and inflammatory diseases, however, the efficacy of anti-tumor activities remains to be defined. In this study the effects of Codonopsis lanceolata (C. lanceolata) on proliferation, migration and adhesion in lung (A549, H1299) and ovarian cancer (SKOV-3) cells were investigated. To assess and compare the pharmacological effects and production places of C. lanceolata, the ethanolic extracts of C. lanceolata from different places in Korea (Hongseong, Yecheon, Yeongwol, Yanggu, Gangjin, and Hoengseong) were prepared. The extract from Hoengseong county did have only marginal anti-proliferative activity in all the cell lines tested, however, other extracts had little or no effect on cell proliferation. The extracts from Hongseong, Gangjin or Hoengseong county had partial anti-migratory activity in lung cancer cells, but not in ovarian cancer cells. In addition, the extract from Hoengseong county had partial anti-adhesive activity in ovarian cancer cells, however, other extracts did not affect cell adhesion in both lung and ovarian cancer cells. Taken together, these findings provide the first description of anti-tumor efficacy of C. lanceolata from different production places in Korea, and suggest that C. lanceolata from Hoengseong county may have therapeutic potential in lung and ovarian cancers.

Effects of Biomedical Ethics Education on Moral sensitivity, Critical thinking and Biomedical ethics Awareness of Nursing Students (생명의료 윤리교육이 간호학생의 도덕적 민감성, 비판적 사고성향, 생명의료 윤리의식에 미치는 효과)

  • Kim, Kyung-Ah;Jeong, Gye-Seon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.2
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    • pp.240-249
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    • 2019
  • The purpose of this study was to find the effect of systemic biomedical ethics education program on moral sensitivity, critical thinking disposition and consciousness of biomedical ethics nursing student. This study is a quasi-experimental research design and repeated measured ANOVA was used to analyzed the collected data statistically on this study. Data was collected from 1st September to 31 of December 2014. Nursing students and nurses in A and S cities participated in this study as subjects. 32 nursing students were assigned to an experimental group, and 33 nursing students were assigned to control group A, 26 nurses were assigned control group B, total subjects were 91. There are significant different in consciousness of biomedical ethics(F=3.432, p=.037). In the category of consciousness of biomedical ethics, there are significant different in 'right to life of fetus'(F=4.476, p=.014) and 'prenatal diagnosis of fetus'(F=6.207, p=.003), and 'right to life of newborn(F=6.207, p=.003) between experimental group and two control groups. The biomedical ethics education influenced the positive effect on moral sensitivity, critical thinking disposition and consciousness of biomedical ethics of nursing students, and shown the significant effect to enhance the consciousness of biomedical ethics for nursing students.

Comparison of the Migration and Absorption of Calcium and Magnesium in Apple Leaves Sprayed with Plant Nutrients Prepared by Wet Nano-grinding Technology (습식 나노화 공정기술 적용 식물 영양제를 살포한 사과의 칼슘과 마그네슘 이동 및 흡수율 비교)

  • Park, Jae-Ryoung;Kim, Eun-Gyeong;Lee, Seung Hyun;Chung, Il Kyung;Kim, Kyung-Min
    • Journal of Life Science
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    • v.29 no.7
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    • pp.769-773
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    • 2019
  • In this study, the migration route and the absorption rate of calcium and magnesium in apple leaves were compared and analyzed using plant nutrients prepared by wet nano-grinding technology. The plant nutrients were sprayed onto the leaves to confirm the component content and the movement route of the nanoized calcium and magnesium. At 2, 4, and 8 weeks after the plant nutrient treatment, the apple leaves were divided into petiole, lamina, and side, and SEM and EDS were used to measure the calcium and magnesium contents. The calcium and magnesium contents of the petiole increased from the 4th week after plant nutrient application to 1,115% at the 8th week. The calcium and magnesium contents of the lamina decreased after spraying but increased after 4 weeks. The calcium and magnesium contents increased in the side of the leaves compared to the control, reaching 673% after 4 weeks. The calcium and magnesium contents increased with increasing duration in all plots when compared with the control unsprayed leaves, suggesting that the usually poorly soluble calcium and magnesium were transferred from the petioles to the lamina. The results of this study indicate that improved calcium and magnesium absorption could be obtained in crops other than apples using plant nutrients produced through wet nano-processing technology. This technology is also expected to be applicable to natural products and bioindustries.

Evaluation of the Biological Activity Affected by Extracting Solvents of Rosemary (Rosmarinus officinalis L.) (로즈마리(Rosmarinus officinalis L.) 극성별 용매 추출물의 생리활성 검증)

  • Li, Ke;Yang, Kyeong Hee;Guo, Lu;Cui, Zhengwei;Son, Beung Gu;Kang, Jum Soon;Lee, Yong Jae;Park, Young Hoon;Je, Beong Il;Choi, Young Whan
    • Journal of Life Science
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    • v.29 no.1
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    • pp.69-75
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    • 2019
  • Rosemary (Rosmarinus officinalis L.) is widely used as a food material. Although various physiological activities of rosemary have been reported, there have been no studies on the physiological activity of solvent extracts with different polarities. Rosemary extracts were obtained by extraction of dried powder using 0%, 25%, 50%, 70%, and 95% ethanol (EtOH) in distilled water, methanol, ethyl acetate, and hexane. As these ratios of EtOH are generally chosen by default and scarcely optimized, we investigated the impact of the composition of EtOH in distilled water on extract-related characteristics, such as DPPH free radical scavenging and ${\alpha}$-glucosidase inhibition, on the differentiation of 3T3-L1 adipocytes and inhibition of tyrosinase. Adipogenesis inhibition was highest at 70% EtOH. DPPH scavenging activity and inhibition of tyrosinase activity were reduced with 50% EtOH in water. However, inhibition of ${\alpha}$-glucosidase activity was higher in 50% EtOH in water. The best solvents in terms of DPPH scavenging activity, inhibition of tyrosinase and ${\alpha}$-glucosidase, and differentiation of adipocytes obtained with different concentrations of EtOH, although a lower similar activities were found with 50% ethanol. Considering the extraction solvents, a ratio of EtOH in water gives different content and constituents of compounds. These differences will give activities inhibition of adipogenesis, tyrosinase, ${\alpha}$-glucosidase activity, and DPPH scavenging activity.

Ethical Issues in the Forth Industrial Revolution and the Enhancement of Bioethics Education in Korean Universities (4차 산업혁명 시대의 윤리적 이슈와 대학의 생명윤리교육 방향 제고)

  • KIM, Sookyung;LEE, Kyunghwa;KIM, Sanghee
    • Korean Journal of Medical Ethics
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    • v.21 no.4
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    • pp.330-343
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    • 2018
  • This article explores some of the ethical issues associated with the fourth industrial revolution and suggests new directions for bioethics education in Korean universities. Some countries have recently developed guidelines and regulations based on the legal and ethical considerations of the benefits and social risks of new technologies associated with the fourth industrial revolution. Foreign universities have also created courses (both classroom and online) that deal with these issues and help to ensure that these new technologies are developed in an ethically appropriate fashion. In South Korea too there have been attempts to enhance bioethics education to meet the changing demands of society. However, bioethics education in Korea remains focused on traditional bioethical topics and largely neglects the ethical issues related to emerging technologies. Furthermore, Korean universities offer no online courses in bioethics and the classroom courses that do exist are generally treated as electives. In order to improve bioethics education in Korean universities, we suggest that (a) new course should be developed for interprofessional education; (b) courses in bioethics should be treated as required subjects gradually; (c) online courses should be prepared, and (d) universities should continually revise course contents in response to the development of new technologies.

Antioxidant and Whitening Effect of Crocus chrysanthus (Herb.) Herb. Bulb Extracts (골든크로쿠스비늘줄기 추출물의 항산화 및 미백 효과)

  • Kyung Wan Yoo;So Min Lee;So Young Jung;Hyojin Heo;Byungsun Cha;Sofia Brito;Lei Lei;Sang Hun Lee;You-Yeon Chun;Ha Hyeon Jo;Ye Ji Kim;Mi-Gi Lee;Byeong-Mun Kwak;Bum-Ho Bin
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.49 no.1
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    • pp.39-46
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    • 2023
  • In this study, Crocus chrysanthus (Herb.) Herb. bulb extracts were extracted by purified water and ethanol, and their antioxidant and tyrosinase inhibitory activity were measured to see the possibility as a cosmetic material. The yield of the extracts was 1.8% to 6.0%, and the yield decreased as the ethanol concentration increased. DPPH free radical (1,1-diphenyl-2-picrylhydrazyl) scavenging activity was high at 91.97% at 625 ㎍/mL of 70% ethanol extract. The total phenol content was also measured at 447 mg/g, higher than other extraction methods. The whitening effect was confirmed through in vitro tyrosinase inhibitory activity. As the ethanol concentration of the extracts increased, the tyrosinase inhibitory activity increased, and 70% and 94.5% ethanol extracts showed high inhibitory activity. Therefore, the Crocus chrysanthus (Herb.) Herb. bulb extracts confirmed its potential as a cosmetic material through antioxidant and whitening effects.

Development of Vegetable Alternative Materials for Mink Oil (밍크 오일의 식물성 대체원료 개발)

  • Seok-Ju Lee;Min-Tae Kim;So Min Lee;So Young Jung;Sofia Brito;Hyojin Heo;Byungsun Cha;Sang Hun Lee;Lei Lei;Ha Hyeon Jo;You-Yeon Chun;Ye Ji Kim;Mi-Gi Lee;Byeong-Mun Kwak;Bum-Ho Bin
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.49 no.1
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    • pp.1-8
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    • 2023
  • This study focused on the development of a vegetable recombinated oil to mimic the animal-derived mink oil. Various vegetable oils and fatty acid substrates were mixed and an immobilized enzyme was utilized in the reaction to synthesize a plant-derived mink oil through deacidification and purification processes. The chemical composition and thermal properties of the recombined oil were confirmed using gas chromatography and differential scanning calorimetry. Our results show a high similarity between mink oil and our synthesized plant-derived mink oil, revealing the potential of utilizing vegetable alternatives for the substitution of animal raw materials, which have been gradually discontinued as cosmetic ingredients.

Korean representation of biotechnology : For college students and lay adults (생명공학에 대한 한국인들의 표상: 대학생들과 일반 성인들을 중심으로)

  • Kyo-Heon Kim
    • Korean Journal of Culture and Social Issue
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    • v.8 no.1
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    • pp.165-187
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    • 2002
  • This study examines Korean representation of the biotechnology and psychological factors which can influence lay people's perception and attitude about biotechnology. Korean college students(N=433) and lay adults(N=90) whom had college education participated in the study. Participants of the study 1 were asked to list words which comes to mind when associate with the biotechnology in broad sense, and several specific applications in health, medicines, agriculture and research. Participants of the study 2 were asked to list possible benefits and costs of biotechnology and their specific applications. In study 3, Participants responded the questionnaires about perceptions and attitudes of biotechnology. Korean people associated the biotechnology with its costs or risks and benefits. Korean college students mainly got the informations of the biotechnology from TV, newspapers, or internet. They trusted the scientist group and NGO group on their judgements about the assessment of risk and benefit of the biotechnology. College students showed the positive attitude with the applications in medicines and negative attitude with the applications in agriculture and public using of individual's genetic information. The radicalism, sensitivity in behavioral activation system, and trust/cynicism were to be found as a significant influencing factor for interest/knowledge and behavioral intention in related with biotechnology. Finally, more extensive knowledge of biotechnology did not lead to greater acceptance of it.

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