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Development of Vegetable Alternative Materials for Mink Oil

밍크 오일의 식물성 대체원료 개발

  • Seok-Ju Lee (Samkwang-chem R&D center) ;
  • Min-Tae Kim (Samkwang-chem R&D center) ;
  • So Min Lee (Department of Biological Science, Ajou University) ;
  • So Young Jung (Department of Applied Biotechnology, Ajou University ) ;
  • Sofia Brito (Department of Applied Biotechnology, Ajou University ) ;
  • Hyojin Heo (Department of Applied Biotechnology, Ajou University ) ;
  • Byungsun Cha (Department of Biological Science, Ajou University) ;
  • Sang Hun Lee (Department of Biological Science, Ajou University) ;
  • Lei Lei (Department of Biological Science, Ajou University) ;
  • Ha Hyeon Jo (Department of Biological Science, Ajou University) ;
  • You-Yeon Chun (Department of Biological Science, Ajou University) ;
  • Ye Ji Kim (Department of Biological Science, Ajou University) ;
  • Mi-Gi Lee (GBSA, Gyeonggido Business and Science Accelerator) ;
  • Byeong-Mun Kwak (Department of Biological Science, Ajou University) ;
  • Bum-Ho Bin (Department of Applied Biotechnology, Ajou University)
  • 이석주 (삼광켐 R&D center) ;
  • 김민태 (삼광켐 R&D center) ;
  • 이소민 (아주대학교 생명과학과) ;
  • 정소영 (아주대학교 응용생명공학과) ;
  • ;
  • 허효진 (아주대학교 응용생명공학과) ;
  • 차병선 (아주대학교 생명과학과) ;
  • 이상훈 (아주대학교 생명과학과) ;
  • ;
  • 조하현 (아주대학교 생명과학과) ;
  • 천유연 (아주대학교 생명과학과) ;
  • 김예지 (아주대학교 생명과학과) ;
  • 이미기 (경기도경제과학진흥원) ;
  • 곽병문 (아주대학교 생명과학과) ;
  • 빈범호 (아주대학교 응용생명공학과)
  • Received : 2022.10.13
  • Accepted : 2023.02.23
  • Published : 2023.03.30

Abstract

This study focused on the development of a vegetable recombinated oil to mimic the animal-derived mink oil. Various vegetable oils and fatty acid substrates were mixed and an immobilized enzyme was utilized in the reaction to synthesize a plant-derived mink oil through deacidification and purification processes. The chemical composition and thermal properties of the recombined oil were confirmed using gas chromatography and differential scanning calorimetry. Our results show a high similarity between mink oil and our synthesized plant-derived mink oil, revealing the potential of utilizing vegetable alternatives for the substitution of animal raw materials, which have been gradually discontinued as cosmetic ingredients.

본 연구는 식물성 유지와 진균 유래 효소를 이용하여, 밍크 오일과 유사한 식물성 재조합 오일의 개발에 관한 것이다. 식물성 유지와 지방산을 혼합하여 고정화 효소를 이용하여 유지의 지방산을 재조합하고, 탈산 및 정제과정을 통해 재조합 유지를 제조하였다. 합성된 재조합 유지는 gas chromatography 및 differential scanning calorimetry를 이용하여 화학적 조성 및 열적 물성 등에 대하여 비교 평가하였다. 본 연구는 밍크 오일과 식물성 재조합 오일의 높은 유사성을 보여주며, 화장품 원료로 점차 활용되지 못하고 있는 동물성 원료의 대체 소재로서 활용 가능성이 기대된다.

Keywords

Acknowledgement

This research was supported by a grant from the National Research Foundation of Korea (NRF) funded by the Korean government (MSIT) (No. 2019005607 to B. H.B. and NRF-2021R1I1A1A01053991 to B. M. K), the Ajou University Research Fund (to B. H. B.), a grant provided by the Korea Initiative for fostering University of Research and Innovation Program of the National Research Foundation (NRF) funded by the Korean government (MSIT) (No. NRF2021M3H1A104892211; to B. H. B. and B. M. K.), the Gyeonggido Business & Science Accelerator (GBSA) grant and the project (to B. H. B and B. M. K) and a grant provided by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (NRF 2021R1A6A1A10044950; to B. H. B and B. M. K).

References

  1. A. V. Dyshuk , N. V. Kondratiuk, and O. I. Petukhova, Omega-acid mink fat as an aspect of commodity evaluation in the strategy for creating new health products, Oles Honchar Dnipro National University, 166 (2018). 
  2. Anonymou s, Final amended report on the safety assessment of mink oil, Int J Toxicol, 24(3), 57 (2005). 
  3. R. K. Bernstein, MD Dr. Bernstein's Diabetes solution, Little, Brown and company, New York (2007). 
  4. B. S. Modjtahedi, S. P. Modjtahedi, A. M. Mansury, and H. I. Maibach, Mosquito bite therapy: evidenced-based, Exog. Dermatol., 3(6), 332 (2004). 
  5. 許浚, Donguibogam: Principles and Practice of Eastern Medicine (東醫寶鑑), 雜病篇卷之八, 諸瘡 (1613). 
  6. 錦里散人, 宜彙, 卷之三, 諸瘡, 火爛傷 (1871). 
  7. L. Cristiano and M. Guagni, Zooceuticals and cosmetic ingredients derived from animals, Cosmetics, 9(1),, 13 (2022). 
  8. C. Barros and R. B. G. Barros, Natural and organic cosmetics : definition and concepts, Journal of Cosmetology & Trichology, 6, 2 (2020). 
  9. K. Fischer, Testing bans and marketing bans under the cosmetics directive, European Food and Feed Law Review, 4(3), 172 (2009). 
  10. N. Abedin, R. Bashar, A. N. Jimmy, and N. A. Khan, Unraveling consumer decisions towards animal ingredients in personal-care items, American Journal of Marketing Research, 6(2), 19 (2020). 
  11. E. Weimann, M. B. B. Silva, G. M. Murata, J. R. Bortolon, A. Dermargos, R. Curi, and E. Hatanaka, Topical anti-inflammatory activity of palmitoleic acid improves wound healing, PLoS One., 13(10), e0205338 (2018).