• Journal of fish pathology
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• v.34 no.2
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• pp.233-241
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• 2021

Polydeoxyribonucleotide (PDRN) is known to accelerate wound healing process by acting on specific adenosine receptors. Differently from the PDRN substances obtained so far from piscine tissues, unique PDRN was prepared recently from Porphyra, a seaweed species. In this study, effects of the Porphyra PDRN was evaluated by inducing artificial skin wounds in Nile tilapia Oreochromis niloticus. The wound recovered almost completely in 2 weeks without any treatment, however only a partial recovery was done after one week. Facilitated healing was observed by PDRN fed for 5 days before wound induction at 10 or 20 mg/kg, against the partially recovered 1-week old wound. The healing effects were identified not only by visual observation, wound area measurement, but also by colorimetric estimations. These novel wound healing effects suggest beneficial therapeutic utility of Porphyra-derived PDRN for wound treatments in fishes occurring from various causes.

• Journal of Korean Society of Forest Science
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• v.105 no.4
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• pp.505-509
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• 2016

This study was conducted to examine the effectiveness of various dressing materials applied to tree wounds in Korea. Significantly higher wound closure rates than those of controls were found when thiophanatemethyl paste (Topsin Paste$^{(R)}$) was applied to Ginkgo biloba, Zelkova serrata, and Prunus yedoensis; lanolin to Z. serrata and P. yedoensis; and tebuconazole paste (Silvacur$^{(R)}$) to P. yedoensis. However, significantly lower wound closure rates than those of controls were found when petroleum jelly (Vaseline$^{(R)}$) was applied to G. biloba, Z. serrata, and P. yedoensis. It was noted that the wounds of Z. serrata and P. yedoensis treated with petroleum jelly expanded due to the death of cambium located at the edge of the wounds. Wound closure rates applied with adhesive - non-toxic to human body (Okong bond$^{(R)}$) were also significantly lower than those of controls in Z. serrata. Pinus densiflora showed no reaction to any experimental wound dressing because of resin secreted from the exposed cambium.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.4
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• pp.242-249
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• 2019

This study examined the wounds and healing of the character as a woman in Samuel Beckett's play, Happy Days, through a microscopic approach by focusing on her inner I, and to study how she tries to heal her wounds. Winnie in Happy Days spends hard times not recognizing her internal wounds and pains. By facing her wounds and pains, however, she starts the process of self-healing, mainly through communicating and sharing her sorrows with her past inner child. Winnie's positive and optimistic character appears to change Willie's behaviors, which may be a positive sign that her wounds and pains will possibly be healed. In conclusion, Winnie has a chance to face her inner wounds and pains while interacting and communicating with her husband Willie, and she is slowly heading for healing her wounded inner I.

• Journal of Korean Society of Forest Science
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• v.111 no.2
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• pp.242-250
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• 2022

Here we aimed to date the year and season of the resin collection from Korean red pines at Worak mountain and investigate the natural healing ability of the wounds using the tree-ring analysis technique. We determined the dating of the resin collection based on the synchronization between the ring-width time series from the wound surface of the experimental trees and the local master chronology, which is the mean time series from the sound surface on the opposite side of the wounds. For the dating of resin collection, we selected thirteen Korean red pines with resin wounds. For the investigation on the annual healing ability of the wounds, we sampled three dead trees out of 13 trees as disks. Through the comparison of the individual ring-width time series from the wounds with the local master chronology, it was verified that the resin collection was undertaken between the spring of 1962 and the autumn of 1975. The mean healing length of the wounds was 15.8 cm over the preceding 42 years, making their annual mean healing 0.38 cm. Through our study we successfully verified the healing ability of the wounded Korean red pines for the resin collection as well as the undocumented resin collection history.

• Journal of Korean Library and Information Science Society
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• v.40 no.1
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• pp.405-431
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• 2009

The purpose of this study was to analyze the experience of dysfunctional family's sons and daughters in bibliotherapy program. To do this, this study collected its data through writings, speaking and term papers of 6 undergraduate students experiencing bibliotherapy program. The collected data were analyzed by phenomenological methods. As a result, the participants experienced 1) recognition of trauma and problems, 2) sympathy and identification, 3) self insight and self understanding, 4) expressing their will to recover trauma and finding solutions, 5) affirmative change, maturity and healing. And also they went through thinking and feeling dynamically in the bibliotherapy program. These results show that the bibliotherapy program helps dysfunctional family's sons and daughters solve their problems and trauma.

• Horticultural Science & Technology
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• v.18 no.6
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• pp.797-801
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• 2000

The present study was conducted to improve the efficiency of transformation mediated by Agrobacterium tumefaciens in hot pepper. Both regeneration ratio and transformation frequency after the cocultivation with A. tumefaciens were affected by inoculation time and artificial wounding. Transformation frequency was increased over 50% by combining artificial wounding with 120 s of inoculation treatment. Confirmation for the transformation of regenerated shoots was carried out by histochemical ${\beta}$-glucuronidase assay and polymerase chain reaction analysis using npt II primer.

• Applied Microscopy
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• v.37 no.4
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• pp.209-217
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• 2007

The system of wound healing is very complex biological processing that includes inflammatory, reepithelialization, and matrix construction. For identification of the transitional pathway of the keratinocytes, we have employed immunohistochemical analysis using cytokeratin antibody after wounding. Epithelium in skin of the frog(Bombina orientalis) was examined with transmission electron microscopy. Cytokeratin was expressed in normal basal and gland cavity cells. At 3-hour basal layer cells were strong positive, however cells of the upper layer were negative reaction. Day1 and 2 after post-wounding, regenerating epithelial cell layer was positive reaction, especially basal layer cells were strong positive. At day 10 after wounding, the degree of positive reaction to basal cells of regenerating epithelial tissue was equal to day 7 wound tissue. At day of 19th, basal and spinous layer cells were strong positive reaction. Regenerating epithelial cells were positive but some basal cells were strong positive at day 27. From this result, we identified that the migration of the keratinocytes in amphibian skin wounds is initiated from basal layer fells and the keratinocytes migrate into basal and middle of the wound area.

• Korean Journal of Culture and Social Issue
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• v.18 no.4
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• pp.505-532
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• 2012

The purpose of this study was to examine the relationship among the growth period wounds, inferiority complex and personality disorder of teenaged students, which affected their mental health. The subjects in this study were 2,110 secondary students. After a survey was conducted, the collected data were analyzed. Whether there would be any differences among the adolescents in those factors were analyzed, and multiple regression analysis and path analysis were carried out. As a result, there were relatively more significant problems with the growth period wounds, inferiority complex, personality disorder and mental health of the students who were girls, who were high schoolers, whose household economy was more vulnerable and whose academic standing was lower. The growth period wound that exerted the largest significant influence on inferiority complex was happiness, followed by wound of security and wound of recognition, and the growth period wound that had the greatest significant impact on personality disorder was happiness, followed by wound of security, wound of confidence, wound of love and wound of equity. The growth period wound that exercised the biggest influence on mental health was happiness, followed by wound of security, wound of confidence, wound of love and wound of equity. As for the influence of the variables related to mental health, the indirect effects of the growth period wounds through personality disorder and inferiority complex were greater than their direct effects. The findings of the study suggest that growth period wounds are likely to lead to inferiority complex and personality disorder and ultimately to the injury of mental health, and indicate the importance of healthy family environments and of educational environments in the growth period.and mental health was analyzed, there was a statistically significant positive(+) correlation among all the variables. Third, the wound factors related to happiness and stability were identified as the factors that affected inferiority complex among the growth period wound factors. Personality disorder was found to be under the influence of the wound factors related to happiness, stability, love, confidence and a sense of equality in the growth period, and mental health was found to be affected by the wound factors related to happiness, stability, confidence, love and a sense of equality. Fourth, the growth period wounds had a direct impact on mental health, and inferiority complex played a significant mediating role at that time. Every subfactor of personality disorder also produced significant mediating effects except the wound factor of pride. The above-mentioned findings suggest that every possible effort should be made to let secondary students get hurt less to promote their mental health and resolve their mental health problems, and that professional counseling intervention and institutional assistance are required to help them to remove their inferiority complex and personality disorder.

• RED RIBBON
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• s.67
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• pp.30-31
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• 2005

아프지 않은 사람이 환자의 고통을 미뤄 짐작할 수는 있으나 완전히 이해하기는 어렵다. 차별 또한 이와 마찬가지이다. 피해 당사자가 아닐 경우 사소한 문제로 보이지만 당사자들 입장에서는 커다란 상처가 될 수 있다. 감염인 · 환자들에게는 병원 또한 그들에게 상처를 주는 장소라고 한다. 병원들이 조금만 신경을 쓰면 충분히 바뀔 수 있는 차별 환경들을 지난 호에 이어 연속적으로 살펴보고자 한다.

• Biomedical Science Letters
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• v.6 no.2
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• pp.119-129
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• 2000

The skin is an organ that has many important roles, including protection against infection, regulation of temperature and fluid loss, and sensory function. Injury to the skin, wound repair normally involves: (1) balanced activity of inflammation, (2) the re-epithelial phase and (3) the matrix formation of remodeling phase. Thus, skin wound healing is a finely controlled biological process involving a series of complex cellular interactions. Laser therapy is being implemented with increasing frequency in medicine. Low intensity laser is one that is capable of producing an energy density so low that any biologic alterations are the result of direct irradiation effect, not thermal events. This study was designed to evaluate the efficacy of low intensity laser therapy on skin wound healing in rabbits. A total of 10 male rabbits (New Zealand White Rabbit), age 8 weeks were used. Skin wound were surgically created dorso-lateral on the flank of 10 rabbits (2$\times$2 cm/damage areas). The experimental animals were treated with 5Hz (830 nm wave length) low-intensity laser (MILTA-01 Model) daily for 10 min (1.6 J/$cm^2$) for 12 days. Control animals were sham treated with the laser head. Laser irradiation animals showed a complete remodeling of the epithelial layer, a positive repair of connective tissues, and enhanced the wound closure rate over time as compared to the control animals. Especially, laser irradiation groups improved fibroblast activity, cellular content, granulation tissue formation, and collagen deposition which is resulted in improving the tensile strength of the wound. These findings suggest that laser photostimulation could accelerate healing of open wound in rabbits, and may be benefit in the treatment of open wound, including decubitis ulcers.