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An Assessment of Post-Injection Transmission Measurement for Attenuation Correction With Rotating Pin Sources in Positron Emission Tomography (양전자방출단층촬영(PET)에서 회전 핀선원과 투과 및 방출 동시 영상 방법을 이용한 감쇠보정 방법 특성에 관한 고찰)

  • Lee, J.R.;Choi, Y.;Lee, K.H.;Kim, S.E.;Chi, D.Y.;Shin, S.A.;Kim, B.T.
    • The Korean Journal of Nuclear Medicine
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    • v.29 no.4
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    • pp.533-540
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    • 1995
  • Attenuation correction is important in producing quantitative positron emission tomography (PET) images. Conventionally, photon attenuation effects are corrected using transmission measurements performed before tracer administration. The pre-injection transmission measurement approach may require a time delay between transmission and emission scans for the tracer studies requiring a long uptake period, about 45 minutes for F-18 deoxyglucose study. The time delay will limit patient throughput and increase the likelihood of patient motion. A technique lot performing simultaneous transmission and emission scans (T+E method) after the tracer injection has been validated. The T+E method substracts the emission counts contaminating the transmission measurements to produce accurate attenuation correction coefficients. This method has been evaluated in experiments using a cylindrical phantom filled with background water (5750 cc) containing $0.4{\mu}Ci/cc$ of F-18 fluoride ion and one insert cylinder (276 cc) containing $4.3{\mu}Ci/cc$. GE $Advance^{TM}$ PET scanner and Ge-68 rotating pin sources for transmission scanning were used for this investigation. Post-injection transmission scan and emission scan were peformed alternatively over time. The error in emission images corrected using post-infection transmission scan to emission images corrected transmission scan was 2.6% at the concentration of $1.0{\mu}Ci/cc$. No obvious differences in image quality and noise were apparent between the two images. The attenuation correction can be accomplished with post-injection transmission measurement using rotating pin sources and this method can significantly shorten the time between transmission and omission scans and thereby reduce the likelihood of patient motion and increase scanning throughput in PET.

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Performance of Waste-air Treating System Composed of Two Alternatively-operating UV/photocatalytic Reactors and Evaluation of Its Characteristics (교대로 운전되는 두 개의 UV/광촉매반응기로 구성된 폐가스 처리시스템의 성능 및 특성 평가)

  • Lee, Eun Ju;Lim, Kwang-Hee
    • Korean Chemical Engineering Research
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    • v.59 no.4
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    • pp.574-583
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    • 2021
  • Waste air containing ethanol (100 ppmv) and hydrogen sulfide (10 ppmv) was continuously treated by waste air-treating system composed of two annular photocatalytic reactors (effective volume: 1.5 L) packed with porous SiO2 media carrying TiO2-anatase photocatalyst, one of which was alternately operated for 32 d/run while the other was regenerated by 100 ℃ hot air with 15 W UV(-A)-light on. As its elimination-behavior of ethanol, the removal efficiencies of ethanol at 1st, 2nd and 3rd operation of the photocatalytic reactor system(A), turned out to be ca. 60, 55 and 54%, respectively, at their steady state condition. Unlike the elimination-behavior of ethanol, its hydrogen sulfide-elimination behavior showed repeated decrease of hydrogen sulfide removal efficiency by its resultant arrival at a lower level of steady state condition. Nevertheless, the removal efficiencies of hydrogen sulfide at 1st, 2nd and 3rd operation of the photocatalytic reactor system, turned out to be ca. 80, 75 and 73%, respectively, at their final steady state condition, higher by ca. 20, 20 and 19% than those of ethanol, respectively. Therefore, assuming that adsorption on porous SiO2-photocatalyst carrier was regarded to belong to a reversible deactivation and that decreased % of removal efficiency due to the reversible deactivation of photocatalyst including the adsorption was independent of the number of its use upon regeneration, the increments of the decreased % of removal efficiency of ethanol and hydrogen sulfide, due to an irreversible deactivation of photocatalyst, for the 3rd use of regenerated photocatalyst, compared with the 2nd use of regenerated photocatalyst, were ca. 1 and 2%, respectively, which was insignificant or the less than those of ca. 5 and 5%, respectively, for the 2nd use of regenerated photocatalyst compared with the 1st use of virgin photocatalyst. This trend of the photocatalytic reactor system was observed to be similar to that of the other alternately-operating photocatalytic reactor system.

Development of microarrayer for manufacturing DNA chip used in genome project (유전자 검색을 위한 DNA 칩 제작용 microarrayer의 개발)

  • Lee, Hyun-Dong;Kim, Ki-Dae;Kim, Chan-Soo;Lim, Yong-Pyo;Park, Jung-Kyu
    • Korean Journal of Agricultural Science
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    • v.30 no.1
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    • pp.76-88
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    • 2003
  • This study exploits the robot system which is necessary in gene study, bio-technology industry. As well, it can achieve the job of DNA chip manufacturing whose use rate has been increased recently. The robot consists of DNA spotting device for spotting DNA on the silylated slide and well plate, bed for fixing well-plate, washing & drying device of washing and drying the pin part of DNA spotting device, distillation-water vessel, and discharge vessel of wash water. We made the term of sticking DNA to the pin on well plate to be 15 seconds. The spot size of DNA was set to be 0.28 mm on the average by bringing the slide into contact with pin for 1 second. At this rate, if DNA is spotted in the minimum space possible of about 0.32mm, it can stick about 8,100 DNA spots on the well plate. Analyzing the procedure: Movement starts. Pin washes, dries, and smears DNA on the well plate. Spots DNA onto 12 chips takes 2 minutes and 50 seconds.

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Fabrication of Honeycomb Adsorbents by Using the Ceramic Paper and Adsorption Characteristics of VOC (세라믹섬유지를 사용한 허니컴 흡착소자 제조 및 VOC 흡착특성)

  • Yoo, Yoon-Jong;Cho, Churl-Hee;Kim, Hong-Soo;Ahn, Young-Soo;Han, Moon-Hee;Jang, Gun-Eik
    • Journal of the Korean Ceramic Society
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    • v.39 no.11
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    • pp.1035-1041
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    • 2002
  • The adhesion characteristics of adsorbent during impregnation of Y-type and ZSM-5type zeolites into ceramic paper were analyzed, as the amount of silica sol in slurry for impregnation was varied. 31 wt% of zeolite particle, which is useful for VOC adsorption, was evenly dispersed and adhered on ceramic paper and original crystal structure of the zeolite remained unchanged even after binder application and heat treatment. Surface area of the impregnated ceramic paper was decreased compared with that of zeolite powder. And it was found to be attributed to the reduction of volume of mesopore while the volume of micropore under $20{\AA}$ was unchanged. Zeolite-impregnated honeycomb cylinder, whose diameter and length were 10 cm and 40 cm, respectively, was subjected to adsorption/desorption test with respect to toluene, MEK, cyclohexanone. All of the VOC's were removed by adsorption with efficiency higher than 97% and from the static adsorption test, $42 Nm^3/h$ of 300 ppmv-VOC-laden air was calculated be treated continuously, when the honeycomb was used in an adsorptive rotor system.

Determination of Dose Correction Factor for Energy and Directional Dependence of the MOSFET Dosimeter in an Anthropomorphic Phantom (인형 모의피폭체내 MOSFET 선량계의 에너지 및 방향 의존도를 고려하기 위한 선량보정인자 결정)

  • Cho, Sung-Koo;Choi, Sang-Hyoun;Na, Seong-Ho;Kim, Chan-Hyeong
    • Journal of Radiation Protection and Research
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    • v.31 no.2
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    • pp.97-104
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    • 2006
  • In recent years, the MOSFET dosimeter has been widely used in various medical applications such as dose verification in radiation therapeutic and diagnostic applications. The MOSFET dosimeter is, however, mainly made of silicon and shows some energy dependence for low energy Photons. Therefore, the MOSFET dosimeter tends to overestimate the dose for low energy scattered photons in a phantom. This study determines the correction factors to compensate these dependences of the MOSFET dosimeter in ATOM phantom. For this, we first constructed a computational model of the ATOM phantom based on the 3D CT image data of the phantom. The voxel phantom was then implemented in a Monte Carlo simulation code and used to calculate the energy spectrum of the photon field at each of the MOSFET dosimeter locations in the phantom. Finally, the correction factors were calculated based on the energy spectrum of the photon field at the dosimeter locations and the pre-determined energy and directional dependence of the MOSFET dosimeter. Our result for $^{60}Co$ and $^{137}Cs$ photon fields shows that the correction factors are distributed within the range of 0.89 and 0.97 considering all the MOSFET dosimeter locations in the phantom.

Performance Evaluation of Underground Pipe with In-Situ Recycled Controlled Low Strength Materials (현장발생토사 재활용 유동성채움재를 이용한 지하매설관의 거동평가)

  • Lee Kwan-Ho;Song Chang-Seob
    • International Journal of Highway Engineering
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    • v.8 no.2 s.28
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    • pp.1-12
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    • 2006
  • An existing Steel pipe, Cast iron pipe and Concrete pipe is can not escaped from aging, specially Metal tube is causing many problems that the quality of water worse is concerned about many rust and mike efficient use of preservation of water. The use of Glassfiber Reinforced Plastic Pipe(GRP PIPE) should be one of the possible scheme to get over these problems. The GRP PIPE has an excellent resistance power and the life is lasting from 50 to 100 years roughly. It's to be useful as a result of high durability and a good construction work also it is a light weight therefore can be expected to short the time of construction and man power. In this research, to executed the small-scaled model test, in-situ model test using CLSM of in-situ soil and to evaluated the stress - strain of the pipe also try to estimated how useful is. From the model test in laboratory, the vertical and horizontal deformation of the GRP PIPE measured in six instance using 200mm and 300mm in diameters. The value of experimentation, theory, analysis got the same results of the test, but the vertical and horizontal deformation gauged in small and the earth pressure was almost zero using CLSM of in-situ soil..

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EFFECT OF DENTIN SURFACE WETNESS ON TENSILE BOND STRENGTH OF SELF ADHESIVE RESIN CEMENTS (상아질 표면 젖음성이 수종 자가접착레진시멘트의 인장접착강도에 미치는 영향)

  • Yoon, Sung-Young;Park, Se-Hee;Kim, Jin-Woo;Cho, Kyung-Mo
    • Restorative Dentistry and Endodontics
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    • v.34 no.2
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    • pp.113-119
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    • 2009
  • The purpose of this study was to compare the tensile bond strength of several self-adhesive resin cements bonded to dentin surfaces with different wet conditions. Three self-adhesive resin cements: Rely-X Unicem (3M ESPE, St. Paul, MN. USA). Embrace Wetbond (Pulpdent. Oakland. MA. USA). Maxcem (Kerr. Orange. CA. USA) were used. Extracted sixty human molars were used. Each self-adhesive resin cement was adhered to the dentin specimens (two rectangular sticks from each molar) in different wet conditions. Tensile bond strength were measured using universal testing machine (EZ Test. Shimadzu corporation. Kyoto. Japan) at a crosshead speed of 1.0mm/min. After the testing. bonding failures of specimens were observed by Operative microscope (OPMI pro, Carl Zeiss. Oberkochen, Germany). T-test was used to evaluate the effect of dentin surface wetness. One-way ANOVA test was used to evaluate the tensile bond strength of self-adhesive resin cements in the same condition. Scheffe's test was used for statistical analyzing at the 95% level of confidence. The result showed that wetness of dentin surface didn't affect tensile bond strength of self-adhesive resin cements and Maxcem showed the lowest tensile bond strength.

Development of the PC Based Color Fish Finder (퍼스널 컴퓨터를 이용한 칼라 어군탐지기의 개발에 관한 연구)

  • 신현옥
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.31 no.3
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    • pp.247-255
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    • 1995
  • This paper describes a personal computer(PC) based color fish finder to improve some problem of the commercial one. The commercial fish finder has no function of the echo data logging and replaying. The authors developed two types of the PC based color fish finder. One is a master type composed of a PC, a digital input-output board, and analog to digital converting (A/D) board and an ultrasonic transceiver unit, the other is a slave type composed of a PC and an A/D board. To test the performances of the master type experiments were carried out in air and in a water tank. It is found that the designed master type fish finder displays very well an eight-colored echogram by one dot resolution to the left side of the PC monitor. Also, the depth of echo signal was corresponds very well to the range from the transducer to a target. The sampling interval of echo signal is about 0.1m and the time of A/D conversion is 30 $\mu$sec. On the other hand, to test the performances of the slave type a raw data of echo signals from a data logger was supplied directly or via RF transceivers to the slave type one. From this experiment, it is confirmed the slave type is useful to replay the echo signal from the data logger or a telesounder.

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Arthroscopic Transosseous Suture Repair for Bankart Lesion with a Flexible Drill Device - An Experimental and Preliminary Clinical Report - (유연성 천공기를 이용한 Bankart 병변의 골관통식 봉합 - 동물 실험 및 예비 임상 결과 보고 -)

  • Park, Jin-Su;Won, Ye-Yeon;Yoo, Jung-Han;Park, Yong-Wook;Noh, Kyu-Chul;Chung, Kuk-Jin;Kim, Hong-Kyun;Hwang, Ji-Hyo;Lee, Young-Bum;Suh, Il-Woo
    • Clinics in Shoulder and Elbow
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    • v.13 no.1
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    • pp.72-78
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    • 2010
  • Purpose: Too develop a flexible drill device that can be inserted into the shoulder joint so that arthroscopic transosseous suture repair for Bankart lesion is possible. Materials and Methods: We created a device composed of a flexible drill unit and a guide pipe unit. The flexible drill unit was made of flexible multifilament wires (1.2 mm in diameter) that was twisted into one cord so that it can flex in any direction and a drill bit (1.2 mm in diameter) that is attached onto one end of the flexible wire. The guide pipe unit was a 150 mm long metal pipe (2.0 mm in inner diameter and 3.0 mm in outer diameter), with one end bent to 30 degrees. The flexible drill set was inserted into the shoulder joint through the posterior portal of the joint. The guide pipe component was placed onto the medial wall of the glenoid so that the pipe was placed 5 mm posterior to the margin of the anterior glenoid rim. The flexible drill was driven through the glenoid by the power drill so that holes were made in the glenoid. A non- absorbable suture was passed through the hole. Tying of a sliding knot tying was accomplished over the capsule and labrum after making a stitch through the capsule and labrum with a suture hook loaded with suture passer. The same procedures were done at the 2 and 4 O'Clock positions of the glenoid. Results: Five cases with Bankart lesion received arthroscopic transosseous repair with our flexible drill device. There were no intraoperative problems. Neither redislocation nor subluxation was reported at final follow-up. Conclusion: Arthroscopic transosseous suture repair without suture anchors and easy tying of a sliding knot are possible with a flexible drill set.

Protective Efficacy of Recombinant Proteins Adenylate Kinase, Nucleoside Diphosphate Kinase, and Heat-Shock Protein 70 against Mycobacterium tuberculosis Infection in Mice (유전자 재조합 단백질 Adenylate Kinase, Nucleoside Diphosphate Kinase와 Heat-Shock Protein 70의 결핵균에 대한 방어면역효능 분석)

  • Lee, Seung-Heon;Lee, Eun-Gae;Kim, Su-Yeon;Cho, Sang-Nae;Park, Young-Kil;Bai, Gill-Han
    • Tuberculosis and Respiratory Diseases
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    • v.58 no.2
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    • pp.142-152
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    • 2005
  • Background : Priming and boosting vaccination strategy has been widely explored for new vaccine development against tuberculosis. As an effort to identify other vaccine candidates, this study was initiated to evaluate protective efficacy of adenylate kinase (AK), nucleoside diphosphate kinase (NdK), and heat shock protein 70 (Hsp70) of Mycobacterium tuberculosis. Method : M. tuberculosis genes encoding AK, NdK, and Hsp70 proteins were amplified by PCR and cloned into E. coli expression vector, pQE30. Recombinant AK, NdK, and Hsp70 was purified through Ni-NTA resin. To evaluate immune responses, we performed enzyme-linked immunosorbent assay (ELISA) for IgG isotype and $IFN-{\gamma}$ after mice were immunized subcutaneously with recombinant proteins delivered in dimethyl dioctadecylammonium bromide (DDA). Immunized- and control groups were challenged by aerosol with M. tuberculosis. The spleens and lungs of mice were removed aseptically and cultured for CFU of M. tuberculosis. Result : Vaccination with recombinant proteins AK, NdK, and Hsp70 delivered in DDA elicited significant level of antibody and $IFN-{\gamma}$ responses to corresponding antigens but no protective immunity comparable to that achieved with Mycobacterium bovis BCG. Conclusion : Recombinant proteins AK, NdK, and Hsp70 do not effectively control growth of M. tuberculosis in mice when immunized with DDA as an adjuvant.