• 대한한의정보학회지
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• 제21권2호
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• pp.11-23
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• 2015

Objectives : Through a comparative study between Sasang constitutional medicine and Syndrome identification and treatment medicine about the theory of diagnosis, the theory of herbal medicine, the theory of prescription, the theory of acupuncture and constitutional medicine to put forward a complementary perfect solution which has good clinical utility. Methods : We compared and sorted out the textbook of Korean Sasang constitutional medicine which named Sasang medicine, and also the textbook of Chinese TCM which was including Basic theory of TCM, Diagnostics of TCM, Science of Chinese materia medica, Pharmacology of traditional Chinese medical formulae, Science of acupuncture and moxibustion, Constitution of TCM, and also related papers. Results : (1) Through a comparative study between Sasang constitutional medicine and Syndrome identification and treatment medicine about diagnosis, herbal medicine, prescription and acupuncture, Sasang constitutional medicine is a medical system which gives priority to balance of organs, when Syndrome identification and treatment medicine is a medical system that gives priority to improve symptom. (2) The prescriptions of Sasang constitutional medicine are used for the treatment of basic pathogenesis in the chronic stage of the disease, which can recover vital qi, when Syndrome identification and treatment medicine are used for the treatment of stage pathogenesis in the acute stage of the disease, which can get rid of pathogenic factors. (3) There are two kind of complementary perfect solution between Sasang constitutional medicine and Syndrome identification and treatment medicine. One perfect complementary medicine is that Sasang constitutional medicine plays a major role when Syndrome identification and treatment medicine plays a supporting role. The other one is that Syndrome identification and treatment medicine plays a major role when Sasang constitutional medicine plays a supporting role. It determined by the usual symptoms and the symptoms now, vital qi and pathogenic factors, symptom and the root cause, acute stage and chronic stage, and the state of pathogenesis. Conclusion : A new perfect complementary medicine can be created which is based on the setting that Sasang constitutional medicine primarily treat the usual symptoms, vital qi, the root cause, chronic stage and basic pathogenesis when Syndrome identification and treatment medicine primarily treat the symptoms now, pathogenic factors, symptom, acute stage and stage pathogenesis.

• 대한본초학회지
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• 제35권1호
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• pp.45-55
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• 2020

Objectives : The purpose of this study is to determine whether Rhus verniciflua Stokes with Latin name Lacca Sinica Exsiccata, and Eucommia ulmoides Oliver with Latin name Eucommiae Cortex Extract Combination (ILF-RE) improves laboratory test results in participants with liver function disorder. Methods : This study was conducted at Woosuk university Korean medicine hospital where participants with high serum alanine transaminase (ALT) levels from 45 to 135 U/L were enrolled. Subjects received ILF-RE 3.6 g (1.2 g/day as ILF-RE) or placebo 3.6 g for 12 weeks. It was confirmed that urushiol was not detected in ILF-RE. The primary outcomes were the decrement degree of serum ALT and gamma-glutamyl transferase (GGT) levels between two groups. The secondary outcomes were the decrement degree of serum aspartate transaminase (AST), alkaline phosphatase (ALP), lactate dehydrogenase (LD), total bilirubin, total cholesterol, triglyceride (TG) and fatty liver index (FLI) levels between two groups. Adverse events, skin prick tests, laboratory tests, and vital signs were observed and analyzed to confirm the safety of ILF-RE.1) Results : In the ILF-RE group, the liver function index ALT, GGT, lipid metabolism index TG, and fatty liver index FLI were significantly decreased compared to the placebo group. There was no significant difference in ILF-RE group in terms of adverse events, severe adverse events, skin prick test, laboratory test, and vital signs compared with placebo group. Conclusions : ILF-RE was found to be effective in improving liver function. In addition, no clinically significant adverse events or body changes were observed during this study.

• 농촌의학ㆍ지역보건
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• 제48권1호
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• pp.41-49
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• 2023

2022년 11월부터 2023년 2월까지 동국대학교 경주병원 이비인후과 외래를 내원한 환자 중에서 소음성 난청을 가진 어선원의 의무기록을 후향적으로 검토하여 소음성 난청을 가진 총 10명의 19개 귀의 청각학적 특성을 분석하였다. 모두 60세 이상의 남자였고 소음에 노출된 기간은 평균적으로 38.9 ± 10.8년으로 장기간 소음에 노출되었으나 난청기간은 평균적으로 13.4 ± 4.3년으로 소음노출에 비해서 늦게 난청을 인지하였다. 고음역 평균역치가 저음역 평균역치보다 높지만, 8 kHz에서 하강하는 청력도를 보였고 고음역 평균 청력역치가 75 dB 초과인 경우는 10.5%이나 저음역 평균 청력역치가 40 dB 초과인 경우가 57.9%를 차지하였다. 순음청력검사상 평균 청력역치는 52.2 ± 7.1 dB, 어음청취역치는 34.0 ± 11.1 dB, 어음명료도검사는 81.5 ± 11.4%, 청성뇌간반응검사의 청력역치는 56.8 ± 6.7 dB, 청성지속반응검사의 청력역치는 63.7 ± 7.6 dB였다. 향후 다기관 연구에서는 어선의 소음의 크기 및 근로시간 등 근로환경에 대한 조사를 같이 시행하여 소음노출을 확인 후 어선원 소음성 난청 청각학적 특성을 분석해야 할 것이다.

• 대한한의학원전학회지
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• 제26권3호
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• pp.19-32
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• 2013

Objective : Chu Cheng(褚澄) was known as the author of Zayaofang(雜藥方) and Chushiyishu(褚氏遺書). His mentions in the medicine have been sufficiently told in his posterity. However, there have been no studies on Chu Cheng and his work like Chushiyishu in Korea. Here, I seek to investigate Chu Cheng and his ideas in the medicine. Method : I investigate Chushiyishu, known as written by Chu Cheng and his scattered portions. Result & Conclusion : His nom de plume(字) is Yandao(彦道). It was supposed that he was born before the year of 420, the era of Dong Jin(東晉) and died in 483. He wrote Zayaofang and Chushiyishu. However, the former was lost. The latter consists of 10 pieces of medical theories. The contents carved on the stone plate was discovered for the first time before 934 at a place presumed as his grave. Then, it was stored as the inner and outer coffins in the tomb of Xiao Guang(蕭廣) in 935 and written on the paper by Buddhist monk Shi Yikan(釋義堪) in 1127. Then, Liu Jixian(劉繼先) carved on the wood for publication and finally, the work was released in 1201. But, it deeply looks that the book was written by other follower. Chu Cheng was a doctor excellent in the inspection and pulse method and his medical ideas prioritized Huo(火) in Mingmen(命門) and Spleen(脾). He expressed his opinions on the four phases of life, sexes and birth defects through Yangjing(陽精) and Yinxue(陰血). In addition, he explained the human pathology through Qixue(氣血). Unsmooth flow of Qi causes diseases by congestion. The entity circulating Yinxue is Yang and protested using urine to treat the hemoptysis(咳血) instead of medicine with cold features. It was frequently mentioned by his predecessors with the fact that Chu Cheng used different medications on housewives from widows and Buddhist nun monks. In addition, Chu Cheng proposed various opinions on cure, diagnosis, treatment, drug usage, pulse positions and hermaphrodites(半陰陽).

• 한국의사학회지
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• 제30권2호
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• pp.83-100
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• 2017

Research purpose : Review of the systematized medical theory of Huangdi within the first series of conversations including questions and answers between Leigong and Huangdi. Conclusions : 1. "Huang-di-Nei-Jing" records the 5 theories of Huangdi's system of thinking (黃帝學派). Among these, the contents of the questions and answers with Leigong led to the establishment of the first of Huangdi's treatises. 2. In the questions and answers exchanged between Leigong and Huangdi, the Suwen (素問) Chapter deals with the areas of Yinyang, Zangfu, Cause and Mechanism of diseases, as well as medical ethics. Moreover, the "Lingshu (靈樞)" Chapter discusses distribution of meridian system, routes of circulation of energies, symptoms, acupuncture therapy and diagnosis, etc. 3. Characteristics of the medicine of Leigong and Huangdi can be summarized as follows: Firstly, 12 meridian systems of the "Jingmai (經脈)" section describes the meridian system that ceaselessly circulates in the shape of loops with the inner and outer aspects linked with each other. Secondly, regarding the methods of diagnosis, the "Yinyangleilun (陰陽類論)" section describes the method of diagnosis through palpation of pulse. In addition, the "Wuse (五色)" section describes visual diagnosis that uses five colors. The Wuhang combination of spleen, liver, kidney of "Shicongronglun (示從容論)" section also includes the Wuhang theory of "Jinwenshangshu (今文尙書)". The "Wuse" section discusses areas of the face and five colors, while the "Yinyangleilun" discusses the 'Yinyancixiongmaifa (陰陽雌雄脈法)', the "Jingmai" discusses the 'Yinyancunkoumaifa (人迎寸口脈法)', and the "Zhengsishilun" and "Fangchengshuailun" discuss 'chifuzhenfa (尺膚診法)'. Thirdly, Huangdi's school of thinking did not neglect bencao (本草) and tangye (湯液), which are discussed in the "Jiejingweilun" and "Shicongronglun" sections.

• 척추신경추나의학회지
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• 제3권2호
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• pp.69-76
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• 2008

Objectives : The purpose of this study is to investigate the relationship among low back pain, lumbar lordosis, obesity and Sasang constitution. Methods : The researcher discriminated the Sasang constitutions of those observed-the inpatient-who were treated from March to May 2008 for low back pain. X-ray were taken in lateral decubitus and the lumbar lordotic angles(LLA) were measured. BMI were measured. This results were statistically analyzed using SPSS 12.0. Results : 1. Among the 31 subjects, distributional rate of Soyangin, Taeumin, and Soeumin were 48.4%, 29.0% and 22.6%. 2. The result showed a significant difference with the Sasang constitution from $\ll$Dongy Suse Bowqn$\gg$. 3. The result showed a difference with the Sasang constitution from the existing result from OSCC II. 4. There was no significant relations between each constitutions and lumbar lordotic angle. 5. There was significant relations between each constitutions and BMI. Conclusions : In this study, The rate of Soyangin, among the low back pain patients, was higher. And the average of BMI was higher in Taeumin.

• 한방안이비인후피부과학회지
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• 제18권2호
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• pp.1-9
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• 2005

Objectives: The objective of this study is to investigate the correlation between genetic studies on atopic dermatitis. sasang constitution, and sasang constitional study on atopic dermatitis. Methods: We retrieved data on PubMed for the papers of genetic study on atopic dermatitis. And for the papers on genetic study of sasang constitution and sasang constitional study of atopic dermatitis, we referred to papers have reported on domestic medical journal and domestic korean medicine journal. And we investigated correlations among the studies. Results: 1. There are two studies on genetic study on atopic dermatitis. One has been performed to find out genes related to atopic dermatitis by case-control study. The other has been to investigate the correlation between atopic dermatitis and the genes their functions were well-known. 2. Gene study on sasang constitution was performed to observe the distribution of the genes which is related with characteristics of sasang constitution, but there was no significant maldistribution of the genes. 3. There was no correlation between genetic study on atopic dermatitis and genetic study on sasang constitution. Conclusion & Discussion: In the Sasang constitutional study of atopic dermatitis, it seems that further studies on genes related to characteristics of skin, character affecting on behavior, and neurobiological difference among Sasang constitution are required as well as studies on distribution of genes related atopic dermatitis.

• Journal of Genetic Medicine
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• 제4권2호
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• pp.200-203
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• 2007

C형 Niemann-Pick병은 NPC1 및 NPC2 유전자의 돌연변이로 인해 발생하는 질환으로 상염색체 열성으로 유전되며 신생아 간염과 간비비대, 이후 안구의 수직운동 마비, 조화운동불능, 구음장애, 근육긴장이상, 경련 등 서서히 진행하는 신경학적 이상을 보이게 된다. 환아는 7개월 된 여아로 출생 후부터 황달과 간비비대가 지속되어 리소솜성 축적질환을 의심하였고 시행한 골수검사상 거품형태의 조직구가 관찰되어 Niemann-Pick병을 진단하였다. 신생아 황달, 간비비대 등 환아의 임상양상을 고려했을 때 C형 Nimann-Pick병이 의심되었고 확진을 위해 시행한 NPC1 유전자 검사에서 c.451_452del (p.Ser151TrpfsX18) 및 새로운 돌연변이인 c.1757+3_6del의 이형접합체임을 확인하여 질환을 확진 하였다.

• Parasites, Hosts and Diseases
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• 제30권3호
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• pp.231-234
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• 1992

조경사업 인부로 일하던 58세 만성 알폴성 환자가 2년 전부터 심와부 불쾌감, 오심, 무른변을 자주 보는 등의 증상을 느꺼오던 중 3개일 전부터 증상이 심해지면서 4 kg의 체중 감소가 있어 내원하였다. 입원 후 시행한 내시 경정사상 십이지 장궤양이 관찰되었고, 대 변검사에서는 분선충(Strongyloides stertoralis)의 rhabditoid 유충이 발견되어, 십이지장궤양 및 분선충증으로 진단되었다. 대변 배양검사에서는 분선충의 filari(orts 유충이 화인되었다. 환자는 분선충증에 대하여 albendazole을 14일간 투여받은 후 하루 4∼5회씩 있던 무른 대변이 정상 대변으로 돌아왔고, 대변 검사 및 대변 배양검사에서 분선충이 더 이상 관찰되지 않았다. 십이지장궤양에 대해서는 colloidal bismuth sulfate로 6주간 치료받은 후, 역시 내시경상 완치되었음이 확인되었고, 건강한 상태로 퇴원하였다. 이 증례는 분선충증이 십이지장궤양과 인과관계가 있을 것임을 시사하는 흥미있는 1례로 생각되었다.

• Parasites, Hosts and Diseases
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• 제32권1호
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• pp.1-6
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• 1994

1992년 6월부터 1993년 10월까지 전주도축장에 출하되는 2세 이상의 한우 1,074두의 복강으로부터 Setaria속 선충류 2종을 검출하여 그 형태를 관찰 감염상황을 조사한 결과를 요약하면 다음과 같다. 이들 사상충은 S. digitata와 S. marshalli었으며 성충의 두부와 미부의 형태적 특징을 광학 및 주사전자현미경으로 관찰하여 분류할 수 있었으며 특히. S. marshalli는 국내 미기록종이다. 또한 전북지방 한우의 Setaria속 감염율은 34.2%이었으며, 이 중에서 S. digitata 25.1%, S. marshalli 2.9%, 중복감염 6.2%로 나타났다. 한편, 검출된 Setaria의 충체총수는 1,254마리이었으며, 그 중 S. digitata 암컷 66.8% 수컷 19.1%. S. marshalli 암컷 9.2%, 수컷 5.0%로 나타났다. 그리고, 그 크기에 있어서 S. digitata 암컷 $7368.09{\;}{\pm}{\;}1229.39{\;}\mu\textrm{m},{\;}수컷{\;}4769.30{\;}{\pm}{\;}389.62{\;}\mu\textrm{m}$ S. marshalli 암컷 $9150.00{\;}{\pm}{\;}1449.59{\;}\mu\textrm{m},{\;}수컷{\;}5068.56{\;}{\pm}{\;}261.07{\;}\mu\textrm{m}$이었다.