• Title/Summary/Keyword: 비대칭계수

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The Discriminating Nature of Dopamine Transporter Image in Parkinsonism: The Competency of Dopaminergic Transporter Imaging in Differential Diagnosis of Parkinsonism: $^{123}I-FP-CIT$ SPECT Study (도파민운반체 영상의 파킨슨증 감별진단 성능: $^{123}I-FP-CIT$ SPECT 연구)

  • Kim, Bom-Sahn;Jang, Sung-June;Eo, Jae-Seon;Park, Eun-Kyung;Kim, Yu-Kyeong;Kim, Jong-Min;Lee, Won-Woo;Kim, Sang-Eun
    • Nuclear Medicine and Molecular Imaging
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    • v.41 no.4
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    • pp.272-279
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    • 2007
  • Purpose: The aim of this study was to evaluate the discriminating nature of $^{123}I-FP-CIT$ SPECT in patients with parkinsonism. Methods: $^{123}I-FP-CIT$ SPECT images acquired from the 18 normal controls; NC ($60.4{\pm}10.0$ yr) and 237 patients with parkinsonism ($65.9{\pm}9.2$ yr) were analyzed. From spatialIy normalized images, regional counts of the caudate, putamen, and occipital lobe were obtained using region of interest method. Binding potential (BP) was calculated with the ratio of specific to nonspecific binding activity at equilibrium. Additionally, the BP ratio of putamen to caudate (PCR) and asymmetric Index (ASI) were measured. Results: BPs of NC $3.37{\pm}0.57,\; 3.10{\pm}0.41,\; 3.23{\pm}0.48$ for caudate, putamen, whole striatum, respectively) had no significant difference with those of essential tremor; ET ($3.31{\pm}0.64,\; 3.06{\pm}0.61,\; 3.14{\pm}0.63$) and Alzheimer's disease; AD (3.33 $\pm$0.60, 3.29$\pm$0.79, 3.31$\pm$0.70), but were higher than those of Parkinson's disease; PD (1.92$\pm$0.74, 1.39$\pm$0.68, 1.64$\pm$0.68), multiple system atrophy; MSA (2.36$\pm$1.07, 2.16$\pm$0.91, 2.26$\pm$0.96), and dementia with Lewy body; DLB (1.95$\pm$0.72, 1.64$\pm$0.65, 1.79$\pm$0.66)(p<0.005). PD had statisticalIy lower values of PER and higher values of ASI than those of NC (p<0.005). And PD had significantIy lower value of PCR, higher ASI and lower BP in the putamen and whole striatum than MSA (p<0.05). Conclusion: Dopamine transporter image of $^{123}I-FP-CIT$ SPECT was a good value in differential diagnosis of parkinsonism.

Sensitivity of Aerosol Optical Parameters on the Atmospheric Radiative Heating Rate (에어로졸 광학변수가 대기복사가열률 산정에 미치는 민감도 분석)

  • Kim, Sang-Woo;Choi, In-Jin;Yoon, Soon-Chang;Kim, Yumi
    • Atmosphere
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    • v.23 no.1
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    • pp.85-92
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    • 2013
  • We estimate atmospheric radiative heating effect of aerosols, based on AErosol RObotic NETwork (AERONET) and lidar observations and radiative transfer calculations. The column radiation model (CRM) is modified to ingest the AERONET measured variables (aerosol optical depth, single scattering albedo, and asymmetric parameter) and subsequently calculate the optical parameters at the 19 bands from the data obtained at four wavelengths. The aerosol radiative forcing at the surface and the top of the atmosphere, and atmospheric absorption on pollution (April 15, 2001) and dust (April 17~18, 2001) days are 3~4 times greater than those on clear-sky days (April 14 and 16, 2001). The atmospheric radiative heating rate (${\Delta}H$) and heating rate by aerosols (${\Delta}H_{aerosol}$) are estimated to be about $3\;K\;day^{-1}$ and $1{\sim}3\;K\;day^{-1}$ for pollution and dust aerosol layers. The sensitivity test showed that a 10% uncertainty in the single scattering albedo results in 30% uncertainties in aerosol radiative forcing at the surface and at the top of the atmosphere and 60% uncertainties in atmospheric forcing, thereby translated to about 35% uncertainties in ${\Delta}H$. This result suggests that atmospheric radiative heating is largely determined by the amount of light-absorbing aerosols.

Characterization and Preparation of Polyimide Copolymer Membranes by Non-Solvent Induced Phase Separation Method (비용매 유도 상전이법을 이용한 공중합체 폴리이미드 분리막의 제조 및 특성평가)

  • Lee, Jung Moo;Park, Jeong Ho;Kim, Deuk Ju;Lee, Myung Gun;Nam, Sang Yong
    • Membrane Journal
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    • v.25 no.4
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    • pp.343-351
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    • 2015
  • In this study, we synthesis polyimide with high gas selectivity using 2,2-bis(3,4-carboxylphenyl) hexafluoropropane, 2,4,6-Trimethyl-1,3-phenylenediamine (DAM) and 4,4-Methylenedianiline (p-MDA), and then the asymmetric membrane was fabricated by non-solvent phase separation method. To confirm the property change of the membrane using different solvent, we measured and compared the viscosity of the polymer solution, cloud point and non-solvent phase separation coefficient. The morphology and gas separation property of membrane prepared by phase separation method was confirmed using Field Emission Scanning Electron Microsope and the single gas permeation measurement apparatus. The single gas ($CH_4$, $N_2$, $O_2$, $CO_2$) permeation property and selectivity value of the membrane prepared with NMP was higher than the membrane prepared with DMAc. We confirmed that the gas selectivity of the membrane increased and the permeation property decreased with increasing of the solvent evaporation time.

Characteristics of Flux Decline in Forward Osmosis Process for Asymmetric Cellulose Membrane (정삼투 공정에 있어 비대칭 셀룰로오즈 막의 투과유속 감소특성)

  • Lee, Keun-Woo;Han, Myeong-Jin;Nam, Suk-Tae
    • Korean Chemical Engineering Research
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    • v.52 no.3
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    • pp.328-334
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    • 2014
  • This study examined the effect of concentration polarization on permeate flux in forward osmosis (FO) membrane process for saline and sucrose solution. The reduction in permeate flux during the FO membrane process is largely due to the formation of concentration polarization on membrane surfaces. The flux reduction due to internal concentration polarization formed on the porous support layer was larger than that due to the external concentration polarization on the active membrane surface. Water permeate flux through the FO membrane increased nonlinearly with the increase in osmotic pressure. The water permeability coefficient was $1.8081{\times}10^{-7}m/s{\cdot}atm$ for draw solution on active layer (DS-AL) mode and $1.0957{\times}10^{-7}m/s{\cdot}atm$ for draw solution on support layer (DS-SL) mode in NaCl solution system. The corresponding membrane resistance was $5.5306{\times}10^6$ and $9.1266{\times}10^6s{\cdot}atm/m$, respectively. With respect to the sucrose solution, the permeate flux for DS-AL mode was 1.33~1.90 times higher than that for DS-SL mode. The corresponding variation in the permeation flux (J) due to osmotic pressure (${\pi}$) would be expressed as $J=-0.0177+0.4506{\pi}-0.0032{\pi}^2$ for the forward and $J=0.0948+0.3292{\pi}-0.0037{\pi}^2$ for the latter.

Volatility of Export Volume and Export Value of Gwangyang Port (광양항의 수출물동량과 수출액의 변동성)

  • Mo, Soo-Won;Lee, Kwang-Bae
    • Journal of Korea Port Economic Association
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    • v.31 no.1
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    • pp.1-14
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    • 2015
  • The standard GARCH model imposing symmetry on the conditional variance, tends to fail in capturing some important features of the data. This paper, hence, introduces the models capturing asymmetric effect. They are the EGARCH model and the GJR model. We provide the systematic comparison of volatility models focusing on the asymmetric effect of news on volatility. Specifically, three diagnostic tests are provided: the sign bias test, the negative size bias test, and the positive size bias test. This paper shows that there is significant evidence of GARCH-type process in the data, as shown by the test for the Ljung-Box Q statistic on the squared residual data. The estimated unconditional density function for squared residual is clearly skewed to the left and markedly leptokurtic when compared with the standard normal distribution. The observation of volatility clustering is also clearly reinforced by the plot of the squared value of residuals of export volume and values. The unconditional variance of both export volumes and export value indicates that large shocks of either sign tend to be followed by large shocks, and small shocks of either sign tend to follow small shocks. The estimated export volume news impact curve for the GARCH also suggests that $h_t$ is overestimated for large negative and positive shocks. The conditional variance equation of the GARCH model for export volumes contains two parameters ${\alpha}$ and ${\beta}$ that are insignificant, indicating that the GARCH model is a poor characterization of the conditional variance of export volumes. The conditional variance equation of the EGARCH model for export value, however, shows a positive sign of parameter ${\delta}$, which is contrary to our expectation, while the GJR model exhibits that parameters ${\alpha}$ and ${\beta}$ are insignificant, and ${\delta}$ is marginally significant. That indicates that the asymmetric volatility models are poor characterization of the conditional variance of export value. It is concluded that the asymmetric EGARCH and GJR model are appropriate in explaining the volatility of export volume, while the symmetric standard GARCH model is good for capturing the volatility.

Computations of Wave Energy by Stream Function Wave Theory (흐름함수파이론에 의한 파랑 에너지의 계산)

  • Lee, Jung Lyul;Pyun, Chong Kun
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.6 no.2
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    • pp.67-75
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    • 1986
  • This paper introduces the nonlinear Stream Function Wave Theory for design waves efficiently to compute the wave energy and energy transport quantities and to analyze the effects of nonlinearities on them. The Stream Function Wave Theory was developed by Dean for case of the observed waves with assymmetric wave profiles and of the design waves with symmetric theoretical wave profiles. Dalrymple later improved the computational procedure by adding two Lagrangian constraints so that more efficient convergence of the iterative numerical method to a specified wave height and to a zero mean free surface displacement resulted. And the Stream Function coefficients are computed numerically by the improved Marquardt algorithm developed for this study. As the result of this study the effects of nonlinearities on the wave quantities of the average potential energy density, the average kinetic energy density result in overestimation by linear wave theory compared to the Stream Function Wave Theory and increase monotonically with decreasing $L^*/L_O$ and with increasing $H/H_B$. The effects of nonlinearities on the group velocity and the wavelength quantities result in underestimation by linear wave theory and increase monotonically with increasing $H/H_B$. Finally the effect of nonlinearity on the average total energy flux results in overestimation for shallow water waves and underestimation for deep water waves by linear wave theory.

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A Meta-Analysis on the Effect of Entrepreneurship on the Entrepreneurial Intention: Mediating Effect of Entrepreneur Education (기업가정신이 창업의지에 미치는 영향에 관한 메타분석: 창업교육의 매개효과)

  • Yoon, Byeong seon;Kim, Chun Kyu
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.15 no.3
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    • pp.207-221
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    • 2020
  • This study conducted a meta-analysis on the effects of innovation, risk-taking, and enterprising on entrepreneurship. From 2013 to 2020, 392 papers, which were judged as quantitative research from doctoral and master thesis, and academic journals published in Korea were selected as research subjects. 28 duplicates of thesis and thesis are excluded. A total of 52 papers were finally selected, excluding 312 papers that were insufficient to be used as research data because there were no statistical values such as correlation coefficients. For the 52 selected papers, the homogeneity of the variables was first verified. As a result of the homogeneity test, the innovativeness, risk-taking, initiative, and entrepreneurship education all showed great effects on heterogeneity, and the average effect size was analyzed by random effect model. The average effect size analyzed was 0.38 ~ 0.49, and all four variables showed moderate average effect size. As a result of analyzing the average effect size by forest plot, all showed proper results. From the results of funnel plot analysis of entrepreneurship education, published errors were confirmed asymmetric. Research data on entrepreneurship education shows that it cannot represent the whole. It is a structural equation model with entrepreneurship and entrepreneurial intention as a parameter. Iinnovation and risk-taking have an impact on entrepreneurship by taking entrepreneurship education as a parameter. Initiative had an effect on the entrepreneurial intention a business, regardless of entrepreneurship education. In a number of studies, university entrepreneurship education has had an impact on the entrepreneurial intention. It should be changed to entrepreneurship education that combines theory and practice. Entrepreneurship education should be transformed into continuous and field-oriented education.

Market Discipline by Depositors : the Case of Mutual Savings Banks in Korea (상호저축은행과 예금자에 의한 시장규율)

  • Park, Jung-Hee
    • The Korean Journal of Financial Management
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    • v.26 no.1
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    • pp.95-125
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    • 2009
  • This paper examines the disciplinary effect of deposits using the semiannual accounting data of mutual savings banks(henceforth 'MSBs') in Korea for the period of 2003 through 2007. I find overall strong evidence in favor of the existence of market discipline in the industry. MSBs with higher BIS ratio and lower NPL ratio turn out to have higher increase rate of deposits than MSBs with lower such ratios. The coefficient of NPL ratio becomes greater with time, suggesting that the effect is cumulative. It turns out that depositors respond more sensitively to NPL ratio than BIS ratio in a period of MSB failure. On the other hand, MSBs turn out to act very positively responding to the depositors' discipline. They increase BIS ratio or decrease NPL ratio following the previous decrease in deposits. Government authorities need to make more efforts to develop a suitable incentive system (e.g. penalties on a false disclosure) to improve the efficiency of disclosure by MSBs. Moreover, they need to acknowledge the importance of NPL ratio as a market disciplinary tool which has been becoming more important, especially in times of MSB failure.

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Detection of Irradiated Milk Formulas using Electron Spin Resonance (전자스핀공명법(ESR)을 이용한 방사선조사 조제유류의 판별)

  • Woon, Jae-Ho;Park, Byeong-Ryong;Choi, Byung-Kook;Kim, Na-Young;Jeong, Hong-Jeom;Cheong, Ki-Soo;Kim, Hee-Sun;Kim, Chang-Seob
    • Journal of Dairy Science and Biotechnology
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    • v.28 no.2
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    • pp.13-18
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    • 2010
  • Electron Spin Resonance (ESR) spectroscopy has been used to detect the presence of radiation-induced free radicals in biological samples since the mid 1950s and to irradiate foods containing cellulose, crystalline sugar, and bone. Therefore, we analyzed the ESR spectrum of irradiated infant formula and its ingredients in this study. Samples were irradiated with 2 different radiation sources of $^{60}Co$ gamma rays and electron beams (EBs), and the absorbed doses were 0, 1, 3, 5, and 7 kGy. ESR measurements were performed under normal atmospheric conditions using a JEOL JES-FA100 spectrometer equipped with an X-band bridge. Irradiated infant formula showed anunsymmetrical spectrum ($g_1$=2.0050, $g_2$=2.0006); in contrast, non-irradiated samples showed asymmetrical spectrum. The ingredients of irradiated samples showed a multi-component ESR signal in glucose and lactose and a singlet-type spectrum in milk powder (g=2.0050). $R^2$ of the dose-response curve showed a fine linearity of over 0.95 across the entire sample. We also compared the spectra of identical samples irradiated with $^{60}Co$ gamma rays and EBs, because EBs can be used for food irradiation in foreign countries, although this is not permitted in Korea. However, we could not find any significant differences according to the types of radiation source. Thus, ESR spectroscopy can be used to detect irradiated infant formula and several types of primary ingredients in this formula.

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Option Pricing and Sensitivity Evaluation Methodology: Improvement of Speed and Accuracy (옵션 가치 및 민감도 평가 방법: 속도와 정확도 개선에 대한 고찰)

  • Choi, Young-Soo;Oh, Se-Jin;Lee, Won-Chang
    • Communications for Statistical Applications and Methods
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    • v.15 no.4
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    • pp.563-585
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    • 2008
  • This paper presents how to improve the efficiency and accuracy in the pricing and sensitivity evaluation for derivatives, since the need for the evaluation of complicated derivatives is increased. The Monte Carlo(MC) simulation using the quasi random number instead of pseudo random number can improve the elapsed time and accuracy for the valuation of European-type derivatives. However, the quasi MC simulation method has its limit for applying it in the multi-dimensional case such as American-type and path-dependent options due to the increased correlation between dimensions as the dimension of random numbers is increased. In order to complement this problem, we develop a modified method in which correlation values are controlled to be below a pre-specified value. Thus, this method is applicable for the pricing of either derivatives ill which underlying assets or risk factors are several or derivatives having path-dependent or early redemption property. Furthermore, we illustrate that it is important to take an appropriate grid interval for the use of finite difference method(FDM) by applying the FDM to one example of non-symmetrical butterfly spreads.