• Communications of Mathematical Education
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• v.13 no.2
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• pp.701-715
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• 2002

창의성과 지능, 뇌 기능 분화의 관계와 수학 창의성과 지능과의 관계에 대해서는 많은 연구가 이루어지고 있으나 뇌 기능 분화와 수학 창의성, 수학 창의적 문제 해결력과의 관계를 규명은 미흡한 상태이고, Balka(1974)의 연구에서는 수학 창의성과 일반 창의성은 관계가 없다는 연구결과가 있다. 이러한 사실을 바탕으로 생각할 때 뇌 기능 분화와 창의성간의 상관관계의 연구에서 얻어진 결과가 수학 창의성과 관계가 있는지 살펴볼 필요가 있다. 본 연구에서 남녀에 따른 뇌기능 분화의 차이와 좌뇌, 우뇌와 전뇌의 수행 수준이 수학 창의적 문제해결력과는 어떠한 관계가 있는지 알아보기 위해 대구광역시 내에 있는 초등학교 5학년의 40명을 대상으로 뇌 기능 분화 검사, 창의성 검사를 실시하여 서로의 관계를 분석했다. 연구 결과 뇌의 기능 분화 발달은 좌뇌는 남자가 우뇌는 여자가 높았으나 통계적으로 의미가 없었고, 전뇌 집단이 수학 창의적 문제해결력이 가장 높았으므로 전뇌를 고루 발달시킬 수 있는 교수전략에 관한 연구들이 계속 되어져야 할 것이다.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.206-206
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• 1994

1차년도에 F9 EC cell의 분화유도 시스템을 확립한뒤 계속적으로 해양생물로 부터 분리한 여러가지 물질을 처리하여 세포의 형태 변화 및 분화 관련 유전자 즉 laminin Bl, type IV collagen, RAR-$\beta$ 의 발현을 조사하였다. 그 결과 다수의 물질이 F9 세포를 분화시키는데 효과가 있는 것으로 나타났으며, 효과있는 물질들에 대한 구조분석이 계속적으로 실시되고 있다. 뿐만 아니라 분화효과가 있는 물질중에서 그 구조적으로 특이한 성질을 가진 물질에 대하여 이 물질이 암세호의 분화에 미치는 기작에 대해 조사하였다. 구체적인 실험내용을 요약하면 다음과 같다. 1. F9 EC cell에 스크리링할 물질의 처리 후 형태 변화 관찰 2. 분화 maker 유전자의 발현 조사 3, 작용 기작에 대한 조사

• Journal of Life Science
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• v.24 no.10
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• pp.1085-1091
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• 2014

The purpose of this study was to determine the effect of selenate on adipocyte differentiation and to identify genes involved in the modulation of adipogenesis in 3T3-L1 cells. To test the effect of selenate on adipocyte differentiation, adipogenesis was induced in cells using various concentrations ($0-100{\mu}M$) of selenate. Various phases of adipogenesis were induced: postconfluent (PC), early phase (EP, d0-d2), postmitotic growth arrest (PM, d2-d4), and all period (AP). The PC cells exposed to selenate for 24 h displayed dose-dependent inhibition of intracellular lipid droplet accumulation on day 6 of adipogenesis. Two days of selenate treatment at EP or AP inhibited adipogenesis, with an approximately 20-80% reduction in lipid accumulation compared to that of a control (p<0.05). When preadipocytes were exposed to selenate during the PM period, the antiadipogenic effect of selenate was attenuated. Two types of selenoprotein genes (Seps1 and Sepp1) were up-regulated by the selenate treatment during mitotic clonal expansion, whereas these genes were down-regulated during PM growth arrest (p<0.05). The findings demonstrate the antiadipogenic function of selenate and the possible involvement of Sepp1 and Seps1 genes in selenate-inhibited adipogenesis in 3T3-L1 cells.

• Journal of the Korean earth science society
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• v.44 no.2
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• pp.148-160
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• 2023

The Pliny Letter, the first historical record of volcanic eruptions and disasters on Earth, was studied to better understand the Vesuvius' eruption patterns in 79 AD. The two-day eruption, which began at 1 a.m. on August 24th 79 AD, produced large amounts of volcanic ash and pumice, which were carried by the wind and fell on nearby cities. Furthermore, during the eruption, fast-moving pyroclastic flows flowed down the volcano's sides, and several phenomena such as earthquakes and tsunamis occurred. Cities near Mount Vesuvius were buried and destroyed by volcanic ash and pyroclastic flows. Previous studies were collected, analyzed, and investigated and the scope of damage was chosen from Pompeii, Herculaneum, Stabiae, and Oplontis. The sedimentary stratigraphy and thickness vary according to location and distance from Vesuvius in each region. Within the depositional layers, the remains of residents who died during the eruption were also discovered, and 1,150 remains have been discovered in Pompeii, 306 in Herculaneum, 111 in Stabiae, and 54 in Oplontis, but the exact number of people who killed is unknown. The eruption that exhibited the pattern seen in AD 79 was named the Plinian eruption after Pliny and classified as a new type of eruption as a result of Pliny's detailed description of the eruption.

• Journal of Life Science
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• v.33 no.9
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• pp.693-702
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• 2023

The present study examined the rate of cell growth and differentiation potential into adipocytes in A549 lung adenocarcinoma cells exposed to each adipogenic medium containing glucose metabolism hormones, such as thyroxine (T4) thyroid hormone and glucocorticoid (GC) adrenal steroid hormone, as well as pioglitazone (PGZ), a PPARγ agonist. Following each adipogenic treatment for 2 weeks, the rate of cell growth was significantly (p<0.05) inhibited, and the level of telomerase activity was significantly (p<0.05) decreased in the PGZ-based adipogenic medium containing both T4 and GC hormone compared with those containing each T4 or GC hormone. Moreover, the adiposome-like vesicles were highly reacted with Oil-Red O staining solution, and the levels of transcripts expressed in the differentiating adipocytes for adipogenesis, including adinopectin, leptin, and resistin, were significantly (p<0.05) increased in the PGZ-based adipogenic medium containing both T4 and GC hormone compared with those of the adipogenic medium containing each T4 or GC hormone, implying that adipocytic differentiation has fully occurred in the A549 cancer cells. Based on present observations, the PGZ-based adipogenic medium containing both T4 and GC efficiently induces inhibition of cell growth and cellular differentiation into adipocytes in A549 cancer cells rather than in the adipogenic medium containing only T4 or GC hormone. Adipogenic treatment could provide potential probability in cancer chemotherapy.

• The Journal of the Petrological Society of Korea
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• v.20 no.4
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• pp.243-250
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• 2011

This study considers the historical eruption record in 1702 from the volcanological point of view, which is presumed to have occurred from Mt. Baegdusan volcano. The minium volume of erupted materials is estimated to be $1.2km^3$ when calculated with an empirical formula using an isopach line obtained from two points 140 km away from the vent. The 1702 eruption was a paroxysmal one with VEI of 5. The historical record described a deposition of wind-modified fallout ash by movement of hot ash cloud. To prepare for the future eruption, we have to analyze historical literatures and understand characteristics of volcano.

• Korean Journal of Childcare and Education
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• v.7 no.3
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• pp.125-141
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• 2011

This study investigates the mediation effects of trait anxiety in the relationships between reports by middle school adolescents in regards to self-differentiation and parents' marital conflicts. The participants were 252 middle school adolescents attended middle schools in Daegu or Gyeongbuk Province. The collected data were analyzed by Pearson's correlation, single and hierarchical multiple regressions, using SPSS 19.0. The results are as follows. (1) Parents' marital conflicts and trait anxiety were negatively associated with self-differentiation of middle school adolescents. (2) Trait anxiety was positively associated with parents' marital conflicts. (3) Trait anxiety exerted indirect effects on self-differentiation mediated by parents' marital conflicts.

• Journal of radiological science and technology
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• v.25 no.2
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• pp.77-82
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• 2002

It is well known that X-irradiation affects on maturing process of differentiated chondrocytes. Nevertheless, It has been remained elusively whether X-irradiation affects the process of differentiation of mesenchymal cells which differentiate into chondrocyte, fibroblast, or muscle cells. In this study, we examined the effect of X-irradiation (with 1 to 10 Gy) on chondrogenesis using the mesenchymal cells of chick limb bud. Our results show that X-irradiation dose-dependently inhibited chondrogenesis. This result suggests that immature chondroblast-like mesenchymal cells are sensitive to X-irradiation. Moreover, X-irradiation affects not only maturing process of chondrocytes, but also inhibits the chondrogenesis. Taken together, we demonstrate that the whole process of differentiation of mature chondrocytes from mesenchymal cells is affected by X-irradiation and undifferentiated cells were more affected by X-irradiation than mature cells.

• Journal of Convergence for Information Technology
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• v.12 no.3
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• pp.126-131
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• 2022

Obesity is known as a metabolic disease caused by abnormal differentiation of fat tissue due to an imbalance between energy intake and consumption.. The purpose of this study was to confirm the changes in the genes associated with pancreatic lipase activity and pre-adipocyte cell differentiation by treatment of red onion extract treatment. The effect of red onion extract treatment on pre-adipocyte differentiation was evaluated using 3T3-L1 adipocytes, and the activity of related genes was confirmed through Real-Time PCR. As a result of the experiment, the red onion extract inhibit pancreatic lipidase activity by concentration dependent manner. In addition, it was found to inhibit adipocyte differentiation and inhibit the activity of genes(C/EBP-α, C/EBP-β, PPAR-γ) associated with adipocyte differentiation. Through the results of this experiment, it is suggested that the red onion extract can be developed as a high potential material with anti-obesity efficacy by suppressing adipocytic differentiation by controlling genes related to adipocyte differentiation.

• 한국노년학
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• v.29 no.4
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• pp.1629-1644
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• 2009

This study was to examine the relationship between self-differentiation and mental health of elderly couples. This study also tries to investigate the effect of self-differentiation on mental health. Data were collected using self-administered questionnaire method with 271 elderly couples over 55 years old who lived in Chollabuk-Do province. The results showed that first, there was no significant difference in the level of total self-differentiation between husbands and wives. While the level of mental health(depression, somatization) were higher for wives than for husbands. Second, both husbands' and wives' mental health were negatively correlated with self-differentiation. Finally, results of multiple regression analyses showed that both husbands' and wives' mental health were negatively influenced by self-differentiation. Specifically, the variable significant affecting the husbands' mental health was the emotional reactivity of self-differentiation and the variable significant wives' mental health was the emotional cut-off of self-differentiation. These findings confirmed the concept of self-differentiation in applying to mental health of elderly couples.